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A new coumarin derivative, 7-O-methylparamicoumarin A (1), has been isolated from the roots of Chionanthus retusus, together with seven known compounds. The structure of new compound 1 was determined through spectroscopic and MS analyses. Among the isolates, luteolin (3), quercetin (4), and apigenin (5) exhibited cytotoxicities with IC50 values of 13.69 ± 1.10, 10.41 ± 0.79, and 12.25 ± 0.91 μM, respectively, against DLD-1 cell line. Luteolin (3), quercetin (4), and apigenin (5) also exhibited cytotoxicities with IC50 values of 15.35 ± 1.24, 13.52 ± 0.87, and 19.48 ± 1.26 μM, respectively, against CCRF-CEM cell line. In addition, kaempferol (2), apigenin (5), 3,3′,5,5′,7-pentahydroxyflavanone (6), and oleuropein (8) showed potent inhibition with IC50 values of 24.84 ± 1.95, 27.18 ± 1.82, 25.18 ± 2.07, and 28.14 ± 1.66 μM, respectively, against LPS-induced NO generation. [ABSTRACT FROM AUTHOR]

A new cis-caffeoyl coumarin glycoside, cichorigenin-5-O-(4′-cis-caffeoyl)-β-D-glucopyranoside (1), wasisolated from the stem barks of Fraxinus depauperata, together with two known coumarins, cichorigenin (2) and esculin (3). The chemical structures of compounds 1-3 were elucidated through spectroscopic and chemical analysis, as well as by comparison with the literature. Compounds 2 and 3 are reported from this species for the first time. [ABSTRACT FROM AUTHOR]

Phytochemical investigation of the stem of Syringa pinnatifolia Hemsl led to the isolation of 13 lignans (4-12, 14-17) and four phenolic compounds (1-3, 13), in which a new lignan (14) was isolated from this plant and compounds 5 and 6 were found for the first time in the genus Syringa. Lignans are major compounds in this plant, which may be used as chemotaxonomic markers for the genus Syringa. [ABSTRACT FROM AUTHOR]

An investigation of ethyl acetate extracts from Syringa pinnatifolia has led to the isolation of one new lignan (1) together with three known compounds (2-4). The structures of compounds 1-4 were identified by UV, IR, ESI-MS, and 1D NMR and 2D NMR. 2,2-Diphenyl-1-picryhydrazyl (DPPH) was used to evaluate the antioxidant activity of the compounds for the radical scavenging capacity. All of the compounds showed strong antioxidant activity. [ABSTRACT FROM AUTHOR]

Two new iridoid type monoterpenoids, named syringopicrogenin D ( 1) and syringopicrogenin E ( 2), were isolated from the EtOH extract of the fresh leaves of Syringa oblate Lindl. The structures of 1 and 2 were elucidated by analyzing spectroscopic data and comparing their NMR data with those of the previously reported compound 1a. [ABSTRACT FROM AUTHOR]

A new natural compound, esculetin-5-O-β-D-glucopyranoside (1), along with two known flavonoids, quercetin (2) and kaempferol-3-β-D-glucopyranoside (3), was purified from the heartwood of Fraxinus velutina. Their chemical structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR, and MS techniques. [ABSTRACT FROM AUTHOR]

The article presents a study on triterpenoids and steroids from Forsythia suspensa Vahl, a deciduous shrub of the Oleaceae family. The leaves of plant were collected in October 2009 from the Dongyangpo production base, Jingxing County, Hebei Province by researcher Jianhua Wang, Pharmacognosy Laboratory, School of Pharmaceutical Sciences, Hebei Medical University.