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Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Regional water scarcity is among the most urgent challenges of global climate change. Atmospheric water harvesting is a promising method to mitigate these challenges, and the atmospheric water generator (AWG) is already an established technology. Although this method can produce over 10,000 L of water per day, the water's quality has not been studied in depth. Air pollutants, especially volatile organic compounds (VOCs), are potential contaminants of water produced from air. We evaluated the chemical and physical parameters of different VOCs that might influence their ability to be transferred from air to AWG water. Our findings strongly suggest that the ability to form hydrogen bonds is a key factor in this transfer. Henry's law constant, polarity, and intrinsic solubility were the main predictors of a VOC's transfer to AWG water. Hence, aliphatic or aromatic compounds (such as benzene or octane) were not found at significant concentrations in AWG water (e.g. above WHO guidelines), whereas ammonia and alcohol compounds were. This should be taken into consideration when analyzing potential contaminants in harvested atmospheric water. The condensation process itself was also found to enhance the transfer of VOCs into water droplets, and higher relative humidity (%RH) also increased VOC transfer. Gas-phase infrared spectrum analysis of VOCs at different %RH revealed possible interactions between water vapor and specific VOCs in the air. However, our main conclusion from this study is that VOC transfer from the air into AWG water occurs predominantly via dissolution in the condensed droplets, and strongly depends on their chemical properties of polarity and hydrogen-bond formation., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Urban Black Carbon (BC) emissions from light-duty gasoline vehicles (LDGVs) are challenging to quantify in real-world settings. This study employed a Portable Emission Measurement System (PEMS) to assess BC emissions from five LDGVs on urban roads. We also developed five machine learning (ML) models based on On-Board Diagnostics (OBD) data to predict BC emissions. Among these, the Random Forest (RF) model consistently demonstrates the best ability to predict BC emissions across all tested LDGVs, with R 2 values exceeding 0.6. Integrating OBD-based ML models within vehicles could enable real-time BC monitoring and aid emission reduction strategies. We observed a strong correlation between BC emissions and engine parameters, such as engine speed and load (R 2 values between 0.5 and 0.9). Furthermore, China VI standard-compliant LDGVs showed minor differences in BC emissions across urban road types. Vehicles equipped with gasoline direct injection (GDI) engines registered BC emission factors (EFs) of 0.141 ± 0.038 mg/km, an increase of 23.7% compared to their port fuel injection (PFI) counterparts, which averaged 0.114 ± 0.049 mg/km., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

β-caryophyllonic acid (BCA), as an important precursor of aqueous secondary organic aerosols (aqSOA), has adverse effects on the atmospheric environment and human health. However, the key atmospheric chemical reaction process in which BCA participates in the formation of aqueous secondary organic aerosols is still unclear. In this study, the reaction mechanism and kinetics of BCA with ·OH and O 3 were investigated by quantum chemical calculations. The initiation reactions between BCA and ·OH include addition and H-abstraction reaction pathways, subsequent intermediates will also react with O 2 , ultimately undergo a cracking reaction to generate small molecular substances. The reaction of BCA with O 3 can generate primary ozone oxides and the Criegee Intermediates oIM3, subsequent main reaction products include keto-BCA, as well as other small molecule aqSOA precursors. The entire reaction process increases the O/C ratio of aqSOA in the aqueous phase and generates products of small molecules such as 4-formylpropionic acid, which plays an important role in the formation of aqSOA. At 298K, the transformation rate constants of BCA initiated by ·OH and O 3 are 1.47 × 10 10  M -1  s -1 and 3.16 × 10 5  M -1  s -1 , respectively, the atmospheric lifetimes of BCA reacting with ·OH range from 0.86 h-5.40 h, while the lifetimes of BCA reacting with O 3 range from 0.44 h-10.04 years. This suggests that BCA primarily reacts with ·OH. However, under higher O 3 concentrations, its ozonolysis becomes significant, promoting the formation of aqSOA. According to the risk assessment, the toxicity of most transformation products (TPs) gradually decreased, but the residual developmental toxicity could not be ignored. In this paper, the atmospheric liquid phase oxidation mechanisms of sesquiterpene unsaturated derived acid were studied from the microscopic level, which has guiding significance for the formation and transformation of aqSOA in atmosphere., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Particulate matter from motor vehicle exhaust is a type of important atmospheric particulates, which can absorb sunlight affecting its photochemical behavior. However, the photochemical activity of water-soluble organic compounds (WSOC) in motor vehicle exhaust particulate matter has not been explored. Here, we applied WSOC in particulate matter from motor vehicle exhaust to investigate the photogenerating ability of its reactive oxygen species (ROS) and its effect based on model phenol photodegradation with the comparison between WSOC in diesel particulate matter and in gasoline particulate matter. The WSOC in diesel particulate matter indicates higher abililty to generate ROS. The main active substance produced by WSOC in the presence of light is 3 WSOC*, the secondary substance is 1 O 2 , and small amounts of ·OH and O 2 · - are also produced. Less active material was produced as WSOC photoaging time increases. Furthermore, the WSOC in diesel particulate matter is more sensitive to light exposure compared to WSOC in gasoline particulate matter. The effects of common atmospheric ionic components on model phenol photodegradation were also explored. Whether WSOC of diesel particulate matter or WSOC of gasoline particulate matter, ammonium nitrate, ammonium sulfate, and ferric chloride promote degradation of model phenol, and copper sulfate inhibited model phenol degradation. However, a different trend emerged with the addition of sodium chloride, which promoted the degradation of model phenol in WSOC of diesel particulate matter and inhibited the degradation in WSOC of gasoline particulate matter., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Passive air samplers were used to monitor polychlorodibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and dioxin-like polychlorobiphenyls (dl-PCBs) between 2020 and 2022 in four residential areas around Bien Hoa hot spot (BHS) including Trung Dung (TD), Tan Phong (TP), Quang Vinh (QV), and Buu Long (BL). The total toxic equivalents of PCDD/Fs and dl-PCBs (∑TEQs) were highest in the TD area, from 284 to 642 fg TEQ/PUF day. Next was the QV area, where ∑TEQs ranged from 229 to 569 fg TEQ/PUF day. Then, ∑TEQs varied from 205 to 503 fg TEQ/PUF day in the TP area. The lowest ∑TEQs were between 179 and 385 fg TEQ/PUF day in the BL area. The temporal, spatial, and seasonal variations in concentrations of PCDD/Fs and dl-PCBs were related to the prevailing wind direction and the distance from each area to the dioxin hot spot. The average ∑TEQs for all four areas surrounding BHS in the dry season (423 fg TEQ/PUF day) were 1.4 times higher than in the rainy season (303 fg TEQ/PUF day). Health risk assessments from airborne dioxin exposure were estimated using the average daily doses through inhalation (ADDI). The ADDI for residents surrounding BHS ranged from 14.6 to 208 fg TEQ/kg BW/day. The ADDI values by areas were as follows: 23.2-208 fg TEQ/kg BW/day in the TD, 18.7-184 fg TEQ/kg BW/day in the QV, 16.7-163 fg TEQ/kg BW/day in the TP, and 14.6-125 fg TEQ/kg BW/day in the BL. These ADDI values remained within and below the 10% threshold of the WHO-recommended tolerable daily intake (100-400 fg TEQ/kg BW/day). It is necessary to control the excavation activities inside the BHS and cover the temporary storage sites of dioxin-contaminated materials to minimize the emissions of PCDD/Fs and dl-PCB into the ambient air., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Exposure to air pollutants like sulfur dioxide (SO 2 ), nitrogen oxides (NO x ), and ozone (O 3 ) is associated with adverse health effects, particularly with exacerbations of asthma symptoms and new asthma cases in both children and adults. While fixed-site monitoring (FSM) stations are commonly used in air pollutant exposure studies, they may not fully capture personal exposures due to limitations such as inadequate consideration of daily routines and indoor/outdoor concentration variations. In this study, to enhance the accuracy of personal exposure calculated by using FSM data, individual's daily activity routine, encompassing both indoor and outdoor environments, were incorporated by using indoor-to-outdoor concentration ratios. Three methodologies were compared to assess the accuracy of exposure calculations: (i) direct exposure determination employing passive samplers (PS), (ii) personal exposure calculated using FSM data alone, and (iii) personal exposure calculated using FSM data refined by integrating local average individual daily activity routines and indoor-to-outdoor ratios. The results demonstrate that the refined method (iii) yields substantial improvements in estimated exposure levels, reducing the average error from 1.4% to 0.4% for NO 2 , from 72.1% to 12.7% for SO 2 , and from 323.4% to 24.9% for O 3 ., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Neyval Costa Reis Junior reports financial support was provided by ArcelorMittal Tubarão. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

A two-stage model integrating a spatiotemporal linear mixed effect (STLME) and a geographic weight regression (GWR) model is proposed to improve the meteorological variables-based aerosol optical depth (AOD) retrieval method (Elterman retrieval model-ERM). The proposed model is referred to as the STG-ERM model. The STG-ERM model is applied over the Beijing-Tianjin-Hebei (BTH) region in China for the years 2019 and 2020. The results show that data coverage increased by 39.0% in 2019 and 40.5% in 2020. Cross-validation of the retrieval results versus multi-angle implementation of atmospheric correction (MAIAC) AOD shows the substantial improvement of the STG-ERM model over earlier meteorological models for AOD estimation, with a determination coefficient (R 2 ) of daily AOD of 0.86, root mean squared prediction error (RMSE) and the relative prediction error (RPE) of 0.10 and 36.14% in 2019 and R 2 of 0.86, RMSE of 0.12 and RPE of 37.86% in 2020. The fused annual mean AOD indicates strong spatial variation with high value in south plain and low value in northwestern mountainous areas of the BTH region. The overall spatial seasonal mean AOD ranges from 0.441 to 0.586, demonstrating strongly seasonal variation. The coverage of STG-ERM retrieved AOD, as determined in this exercise by leaving out part of the meteorological data, affects the accuracy of fused AOD. The coverage of the meteorological data has smaller impact on the fused AOD in the districts with low annual mean AOD of less than 0.35 than that in the districts with high annual mean AOD of greater than 0.6. If available, continuous daily meteorological data with high spatiotemporal resolution can improve the model performance and the accuracy of fused AOD. The STG-ERM model may serve as a valuable approach to provide data to fill gaps in satellite-retrieved AOD products., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Recently, Sustainable Aviation Fuel (SAF) blends and novel combustion technologies have been introduced to reduce aircraft engine emissions. However, there is limited knowledge about the impact of combustion technology and fuel composition on toxicity of primary Particulate Matter (PM) emissions, comparable to regulated non-volatile PM (nvPM). In this study, primary PM was collected on filters using a standardised approach, from both a Rich-Quench-Lean (RQL) combustion rig and a bespoke liquid fuelled Combustion Aerosol Standard (CAST) Generator burning 12 aviation fuels including conventional Jet-A, SAFs, and blends thereof. The fuels varied in aromatics (0-25.2%), sulphur (0-3000 ppm) and hydrogen (13.43-15.31%) contents. Toxicity of the collected primary PM was studied in vitro utilising Air-Liquid Interface (ALI) exposure of lung epithelial cells (Calu-3) in monoculture and co-culture with macrophages (differentiated THP-1 cells). Cells were exposed to PM extracted from filters and nebulised from suspensions using a cloud-based ALI exposure system. Toxicity readout parameters were analysed 24 h after exposure. Results showed presence of genotoxicity and changes in gene expression at dose levels which did not induce cytotoxicity. DNA damage was detected through Comet assay in cells exposed to CAST generated samples. Real-Time PCR performed to investigate the expression profile of genes involved in oxidative stress and DNA repair pathways showed different behaviours after exposure to the various PM samples. No differences were found in pro-inflammatory interleukin-8 secretion. This study indicates that primary PM toxicity is driven by wider factors than fuel composition, highlighting that further work is needed to substantiate the full toxicity of aircraft exhaust PM inclusive of secondary PM emanating from numerous engine technologies across the power range burning conventional Jet-A and SAF., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

The presence of organic compounds on the particulate matter (PM) or aerosols can arise from the condensation of gaseous organic compounds on the existing aerosols, or from organic precursors to form secondary organic aerosols (SOA) through photochemistry. The objective of this study is to characterize organic constituents on aerosols relevant to their emission sources and the key compounds revealing the evolution of aerosols with the use of a novel analytical technique. A time-of-flight mass spectrometry (TOFMS) coupled with comprehensive two-dimensional gas chromatography (GC×GC) was developed using a flow type of modulator instead of a thermal type as a prelude to field applications without the need for cryogen. The methodology of GC×GC-TOFMS is discussed in this study in detail. Since the coarse PM (PM 10-2.5 ) may exhibit with a relatively high OC content compared to PM 2.5 , the GC×GC results have been obtained by analyzing PM 10 samples collected in parallel with OC/EC analysis of PM 2.5 samples at the Lulin Atmospheric Background Station (LABS, 23.47°N, 120.87°E, 2862 m ASL) as the high-mountain background site in East Asia. We found that the organic analytes were in a majority in the range of 12-30 carbon numbers falling in the category of semi-volatile organic compounds (SVOCs) with 43 compounds of alcohol, aldehyde, ketone, and ester varieties if excluding alkanes. Intriguingly, trace amounts of plasticizers and phosphorus flame retardants such as phthalates (PAEs) and triphenyl phosphate (TPP) were also found, likely originating from regions involved in open burning of household solid waste in Southeast Asia or e-waste recycling in southern China and along the long-range transport route. Compounds such as these are unique to the specific sources, demonstrating the wide spread of these hazardous compounds in the environment., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Jia-Lin Wang reports financial support was provided by Ministry of Science and Technology, Taiwan. Chang-Feng Ou-Yang reports statistical analysis was provided by NOAA Air Resources Laboratory. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Within the scope of this study, two equivalent PM 2.5 samplers were designed and developed to eliminate sampling artifacts in the results of atmospheric particulate organic carbon (OC) and particulate polycyclic aromatic hydrocarbons (PAH) caused by volatile organic compounds (VOCs) and gas phase PAH compounds, respectively. A mass loss of less than 10% due to the denuders was observed. Study results showed that if an impregnated denuder is not used, the results of atmospheric particle OC concentrations will be reported with higher values due to positive errors of 53.2 ± 7.23% (median: 52.00%) on average. It was observed that the total error (net error) was still positive, but decreased to an average of 35.1 ± 16.8% (median: 31.0%) after including the negative errors quantified from the backup filter into the calculation. In cases where denuders were not used in the sampling, it was observed that the results with positive errors of 41.0 ± 14.6% (median: 33.8%) on average would be obtained for the total PAHs. Ozone-induced negative interference was the highest in Acenapthylene (28%), followed by Fluoranthane (20%), Phenanthrene (18%), and 15% for Np and Benzo[g,h,i]perylene compounds, relative to their medians. Negative errors of 10% or less were found in all other individual PAH compounds., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Background: There are a few reports on the associations between fine particulate matter (PM 2.5 )-bound heavy metals and lung function., Objectives: To evaluate the associations of single and mixed PM 2.5 -bound heavy metals with lung function., Methods: This study included 316 observations of 224 Chinese adults from the Wuhan-Zhuhai cohort over two study periods, and measured participants' personal PM 2.5 -bound heavy metals and lung function. Three linear mixed models, including the single constituent model, the PM 2.5 -adjusted constituent model, and the constituent residual model were used to evaluate the association between single metal and lung function. Mixed exposure models including Bayesian kernel machine regression (BKMR) model, weighted quantile sum (WQS) model, and Explainable Machine Learning model were used to assess the relationship between PM 2.5 -bound heavy metal mixtures and lung function., Results: In the single exposure analyses, significant negative associations of PM 2.5 -bound lead, antimony, and cadmium with peak expiratory flow (PEF) were observed. In the mixed exposure analyses, significant decreases in forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC), maximal mid-expiratory flow (MMF), and forced expiratory flow at 75% of the pulmonary volume (FEF75) were associated with the increased PM 2.5 -bound heavy metal mixture. The BKMR models suggested negative associations of PM 2.5 -bound lead and antimony with lung function. In addition, PM 2.5 -bound copper was positively associated with FEV1/FVC, MMF, and FEF75. The Explainable Machine Learning models suggested that FEV1/FVC, MMF, and FEF75 decreased with the elevated PM 2.5 -bound lead, manganese, and vanadium, and increased with the elevated PM 2.5 -bound copper., Conclusions: The negative relationships were detected between PM 2.5 -bound heavy metal mixture and FEV1/FVC, MMF, as well as FEF75. Among the PM 2.5 -bound heavy metal mixture, PM 2.5 -bound lead, antimony, manganese, and vanadium were negatively associated with FEV1/FVC, MMF, and FEF75, while PM 2.5 -bound copper was positively associated with FEV1/FVC, MMF, and FEF75., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Ore mineralizations in bedrock and their exploitation may have a negative impact on air quality of surrounding urban areas and, subsequently, on human health. This study uses lichens as bioindicators of atmospheric pollution to evaluate the spatial distribution of potentially toxic elements (PTEs) in the towns close to the massive sulfide deposits of the Iberian Pyrite Belt (IPB) in SW Spain. Altogether 89 native lichen samples of Xanthoria parietina were collected from the mining towns, control towns out of the reach of the mining activity, as well as from distal sampling sites. The samples were analyzed for 29 elements after acid digestion. The concentrations for Co, Ni, Cu, Zn, As, Rb, Mo, Cd, Sn, Sb, Cs, Ba, W, Tl, Pb, S, and Fe are significantly higher in the mining towns in comparison to the control towns. The ore mineral-associated PTEs, including Cu, Zn, As, Ba, and Pb, exhibit extreme concentrations in the urban areas close to the mining activity, and particularly in the small settlement of La Dehesa next to the mineral processing plant and the tailings pond. The distal samples confirm the decrease in the concentrations of all PTEs, and these samples present similar values as in the control areas. The results, point at increased bioaccumulation of PTEs in the lichen thalli of the adjacent urban areas, suggesting that the air quality of the adjacent urban areas is locally impacted by the massive polymetallic sulfide deposits which is enhanced by the mining activity. Therefore, monitoring the urban air quality is recommended., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Annika Parviainen reports financial support was provided by University of Granada. Annika Parviainen reports financial support was provided by Government of Andalusia. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) cause significant environmental concerns. Atmospheric PCDD/Fs permeate water bodies and other ecosystems through wet and dry deposition. In an urban site, dry deposition flux samples of gaseous phase PCDD/Fs were collected by a water surface sampler (WSS) operated between June 2022 and June 2023. There is a conspicuous absence of literature on the direct measurement of dry deposition flux levels in the gaseous phase of PCDD/Fs. In the study, PCDD/Fs in the gas phase reaching the WSS dissolved in the water according to Henry's Law. The PCDD/Fs in the water were transferred to an XAD-2 resin column, sorbing the dissolved PCDD/Fs. The average monthly gas phase dry deposition flux was 34.07 ± 9.35 pg/m 2 -day (7.35 ± 2.16 pg I-TEQ/m 2 -day). The highest flux was measured in March (49.53 pg/m 2 -day), and the lowest was in August (18.64 pg/m 2 -day). These values indicated the direct flux from air to water. The atmospheric concentration of the gas-phase ranged from 68.38 to 126.88 fg/m 3 (13.22-25.01 fg I-TEQ/m 3 ). Dry deposition fluxes and concentrations of atmospheric PCDD/Fs were bigger in the colder months than in the warmer months. This was probably due to a significant increase in residential heating during the colder months, decreased photochemical reactions, and lower mixing heights. Regarding congeners in the dry deposition flux and concentration values in I-TEQ units, 2,3,7,8-TCDD compound predominated with the proportions of 31.61 ± 7.76% and 29.09 ± 12.34%, respectively. Concurrently measured dry deposition flux (F g ) and ambient air concentration (C g ) of PCDD/Fs were considered in the determination of mass transfer coefficient (MTC = F g /C g ) calculation for each PCDD/F congener. The average MTC for targeted 17 PCDD/Fs was 0.45 ± 0.15 cm/s, and it fluctuated between 0.89 ± 0.30 cm/s for 2,3,7,8-TCDF and 0.2 ± 0.16 cm/s for OCDD., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Background: Current knowledge suggests that the gene region containing MUC5B and TOLLIP plays a role in airway defence and airway inflammation, and hence respiratory disease. It is also known that exposure to air pollution increases susceptibility to respiratory disease. We aimed to study whether the effect of air pollutants on the immune response and respiratory symptoms in infants may be modified by polymorphisms in MUC5B and TOLLIP genes., Methods: 359 healthy term infants from the prospective Basel-Bern Infant Lung Development (BILD) birth cohort were included in the study. The main outcome was the score of weekly assessed respiratory symptoms in the first year of life. Using the candidate gene approach, we selected 10 single nucleotide polymorphisms (SNPs) from the MUC5B and TOLLIP regions. Nitrogen dioxide (NO 2 ) and particulate matter ≤10 μm in aerodynamic diameter (PM 10 ) exposure was estimated on a weekly basis. We used generalised additive mixed models adjusted for known covariates. To validate our results in vitro, cells from a lung epithelial cell line were downregulated in TOLLIP expression and exposed to diesel particulate matter (DPM) and polyinosinic-polycytidylic acid., Results: Significant interaction was observed between modelled air pollution (weekly NO 2 exposure) and 5 SNPs within MUC5B and TOLLIP genes regarding respiratory symptoms as outcome: E.g., infants carrying minor alleles of rs5744034, rs3793965 and rs3750920 (all TOLLIP) had an increased risk of respiratory symptoms with increasing NO 2 exposure. In vitro experiments showed that cells downregulated for TOLLIP react differently to environmental pollutant exposure with DPM and viral stimulation., Conclusion: Our findings suggest that the effect of air pollution on respiratory symptoms in infancy may be influenced by the genotype of specific SNPs from the MUC5B and TOLLIP regions. For validation of the findings, we provided in vitro evidence for the interaction of TOLLIP with air pollution., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Urs Frey reports financial support was provided by Swiss National Science Foundation. Celine Ruettimann reports a relationship with Freie Akademische Gesellschaft Basel that includes: funding grants. Philipp Latzin reports a relationship with Vertex that includes: board membership, funding grants, and speaking and lecture fees. Philipp Latzin reports a relationship with Vifor Pharma Switzerland SA that includes: speaking and lecture fees. Philipp Latzin reports a relationship with OM Pharma Ltd that includes: board membership, funding grants, and speaking and lecture fees. Philipp Latzin reports a relationship with Polyphor Ltd that includes: board membership. Philipp Latzin reports a relationship with Santhera Pharmaceuticals Schweiz AG that includes: board membership. Philipp Latzin reports a relationship with Allecra Therapeutics that includes: board membership. Philipp Latzin reports a relationship with Sanofi that includes: board membership. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Nitroaromatic compounds (NACs) in ambient particles are of great concern due to their adverse effects on human health and climate. However, investigations on the characteristics and potential sources of NACs in Southwest China are still scarce. In this study, a field sampling campaign was carried out in the winter of 2022 at a suburban site in Mianyang, Southwest China. A direct injection liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to rapidly determine 10 NACs in fine particulate matter (PM 2.5 ) extracts. The method was sensitive for the quantification of the NACs, with a limit of quantification (LOQ) in the range of 0.092-0.52 ng mL -1 . Then, the developed method was applied to determine the concentrations of nitrophenols (NPs), nitrocatechols (NCs), nitrosalicylic acids (NSAs), and nitronaphthol in PM 2.5 in Mianyang. The average concentration of total NACs was 78.2 ± 31.2 ng m -3 , with daily concentrations ranging from 20.7 to 127.9 ng m -3 . Among the measured NACs, 4-nitrocatechol was the most abundant, accounting for 57.8% of the NACs in winter. The five NPs compounds together contributed to 14% of the NACs, which was lower than in other Chinese cities due to the warm climate in winter in Southwest China. NSAs and nitronaphthol each accounted for less than 5% of the NACs. Three major sources of NACs were identified based on the principal component analysis, including vehicle emissions, biomass burning, and secondary formation. The significant correlation between individual NACs and NO 2 supported their secondary formation sources. The good correlation between NPs and cloud amount further suggested that gas-phase oxidation was the possible NPs formation mechanism. Our findings revealed the important role of nitrocatechols in NACs in Southwest China, implying that more measures should be taken to control biomass burning and aromatic volatile organic compounds emissions to reduce the level of NACs., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

PM 2.5 is a main atmospheric pollutant with various sources and complex chemical compositions, which are influenced by various factors, such as anthropogenic emissions (AE) and meteorological conditions (MC). MC have a significant impacts on variations in atmospheric pollutant; therefore, emission reduction policies and ambient air quality are non-linearly correlated, which hinders the accurate assessment of the effectiveness of control measures. In this study, we conducted online observations of PM 2.5 and its chemical composition in Hohhot, China, from December 1, 2019, to February 29, 2020, to investigate how the chemical compositions of PM 2.5 respond to the variations in AE and MC. Moreover, the random forest (RF) model was used to quantify the contributions of AE and MC to PM 2.5 and its chemical composition during severe hazes and the COVID-19 pandemic lockdown period. During the clean period, MC reduced PM 2.5 concentrations by 124%, while MC incresed PM 2.5 concentrations by 49% during severe pollution episode. Inorganic aerosols (SO 4 2- , NO 3 - , and NH 4 + ) showed the strongest response to MC. MC significantly contributed to PM 2.5 (36%), SO 4 2- (32%), NO 3 - (29%), NH 4 + (28%), OC (22%), and SOC (17%) levels during pollution episodes. From the pre-lockdown to lockdown period, AE (MC) contributed 52% (48%), 81% (19%), 48% (52%), 68% (32%), 59% (41%), and 288% (-188%) to the PM 2.5 , SO 4 2- , NO 3 - , NH 4 + , OC, and SOC reductions, respectively. The variations in MC (especially the increase in relative humidity) rapidly generated meteorologically sensitive species (SO 4 2- , NO 3 - , and NH 4 + ), which led to severe winter pollution. This study provides a reference for assessing the net benefits of emission reduction measures for PM 2.5 and its chemical compositions., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

A comprehensive chemical characterization (water-soluble ions, organic and elemental carbon, water- and methanol-soluble organic carbon, levoglucosan, and major and trace metals) of PM 10 samples collected in a rural area located in the southeast of the Iberian Peninsula was performed. Additionally, the oxidative potential of the samples, used as an indicator of aerosol toxicity, was determined by the ascorbic acid (OP AA ) and dithiothreitol (OP DTT ) assays. The average concentration of PM 10 during the study period, spanning from late winter to early spring, was 20.2 ± 10.8 μg m -3 . Nitrate, carbonate and calcium (accounting for 20% of the average PM 10 mass concentration) and organic matter (with a contribution of 28%) were the main chemical components of PM 10 . Average concentrations of traffic tracers such as elemental carbon, copper and zinc (0.31 μg m -3 , 3 ng m -3 , and 9 ng m -3 , respectively) were low compared with those obtained at an urban site in the same region, due to the almost total absence of traffic in the surrounding of the sampling site. Regarding levoglucosan and K + , which can be considered as tracers of biomass burning, their concentrations (0.12 μg m -3 and 55 ng m -3 , respectively) were in the lower range of values reported for other rural areas in Europe, suggesting a moderate contribution form this source to PM 10 levels. The results of the Pearson's correlation analysis showed that volume-normalised OP AA and OP DTT levels (average values of 0.11 and 0.32 nmol min -1  m -3 , respectively) were sensitive to different PM 10 chemical components. Whereas OP AA was not strongly correlated with any of the species measured, good correlation coefficients of OP DTT with water-soluble organic carbon (r = 0.81) and K + (r = 0.73) were obtained, which points to biomass burning as an important driver of the DTT activity., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Over the past decades, air pollution has caused severe environmental and public health problems. According to the World Health Organization (WHO), fine particulate matter (PM 2.5 ), a key component reflecting air quality, is the fourth leading cause of death worldwide after cardiovascular disease, smoking, and diet. Various research efforts have aimed to develop PM 2.5 forecasting models that can be integrated into a solution to mitigate the adverse effects of air pollution. However, PM 2.5 forecasting is challenging because air pollution data are non-stationary and influenced by multiple random effects. This paper proposes an effective multivariate multi-step ensemble machine learning model for predicting continuous 24-h PM 2.5 concentrations, considering meteorological conditions, the rolling mean of PM 2.5 time series, and temporal features. PM 2.5 is strongly correlated with space and time. Therefore, forecasting results from one location are insufficient to represent the level of air pollution for an entire city. In this study, we established six real-time air quality monitoring sites in different regions, including traffic, residential, and industrial areas in Ho Chi Minh City (HCMC), and generated forecasting results for each station. Various statistical methods are incorporated to evaluate the performance of the model. The experimental results confirm that the model performs well, substantially improving its forecasting accuracy compared to existing PM 2.5 forecasting models developed for HCMC. In addition, we analyze to determine the contribution of different feature groups to model performance. The model can serve as a reference for citizens scheduling local travel and for healthcare providers to provide early warnings., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)

Short-term ambient fine particulate matter (PM 2.5 ) exposure has been related to an increased risk of myocardial infarction (MI) death, but which PM 2.5 constituents are associated with MI death and to what extent remain unclear. We aimed to explore the associations of short-term exposure to PM 2.5 constituents with MI death and evaluate excess mortality. We conducted a time-stratified case-crossover study on 237,492 MI decedents in Jiangsu province, China during 2015-2021. Utilizing a validated PM 2.5 constituents grid dataset at 1 km spatial resolution, we estimated black carbon (BC), organic carbon (OC), sulfate (SO 4 2- ), nitrate (NO 3 - ), ammonium (NH 4 + ), and chloride (Cl - ) exposure by extracting daily concentrations grounding on the home address of each subject. We employed conditional logistic regression models to evaluate the exposure-response relationship between PM 2.5 constituents and MI death. Overall, per interquartile range (IQR) increase of BC (lag 06-day; IQR: 1.75 μg/m 3 ) and SO 4 2- (lag 04-day; IQR: 5.06 μg/m 3 ) exposures were significantly associated with a 3.91% and 2.94% increase in odds of MI death, respectively, and no significant departure from linearity was identified in the exposure-response curves for BC and SO 4 2- . If BC and SO 4 2- exposures were reduced to theoretical minimal risk exposure concentration (0.89 μg/m 3 and 1.51 μg/m 3 ), an estimate of 4.55% and 4.80% MI deaths would be avoided, respectively. We did not find robust associations of OC, NO 3 - , NH 4 + , and Cl - exposures with MI death. Individuals aged ≥80 years were more vulnerable to PM 2.5 constituent exposures in MI death (p for difference <0.05). In conclusion, short-term exposure to PM 2.5 -bound BC and SO 4 2- was significantly associated with increased odds of MI death and resulted in extensive excess mortality, notably in older adults. Our findings emphasized the necessity of reducing toxic PM 2.5 constituent exposures to prevent deaths from MI and warranted further studies on the relative contribution of specific constituents., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Airborne Organic Pollutants (AOPs) reach remote oceanic regions after long range atmospheric transport and deposition, incorporating into natural microbial communities. This study investigated the effects of AOPs on natural microbial communities of the Mediterranean Sea, the Atlantic Ocean and the Bellingshausen Sea, by assessing the impact of both non-polar and polar AOPs on cell abundances, chlorophyll a concentrations and cell viabilities of different microbial groups. Our results indicate that almost all groups, except flagellates in the Bellingshausen Sea, were significantly affected by AOPs. While no significant differences in chlorophyll a concentrations were observed between non-polar and polar AOPs, significant variations in cell abundances were noted. Cell death occurred at AOP concentrations as low as five times the oceanic field levels, likely due to their high chemical activity. Cyanobacteria in temperate waters exhibited the highest sensitivity to AOPs, whereas medium and larger diatoms in the Bellingshausen Sea were more affected than smaller diatoms or flagellates, contrary to the expected size-related sensitivity trend. Additionally, microorganisms in temperate waters were more sensitive to the polar fraction of AOPs compared to the non-polar fraction, which showed an inverse sensitivity pattern. This differential sensitivity is attributed to variations in the ratio of polar to non-polar AOPs in the respective environments. Our findings underscore the varying impacts of AOPs on marine microbial communities across different oceanic regions., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Rapid urbanization and industrialization have intensified air pollution, posing severe health risks and necessitating accurate PM 2.5 predictions for effective urban air quality management. This study distinguishes itself by utilizing high-resolution ERA5 reanalysis data for a grid-based spatial analysis of Istanbul, Türkiye, a densely populated city with diverse pollutant sources. It assesses the predictive accuracy of advanced machine learning (ML) models-Multiple Linear Regression (MLR), Extreme Gradient Boosting (XGBoost), Light Gradient Boosting (LGB), Random Forest (RF), and Nonlinear Autoregressive with Exogenous Inputs (NARX). Notably, it introduces genetic algorithm optimization for the NARX model to enhance its performance. The models were trained on hourly PM 2.5 concentrations from twenty monitoring stations across 2020-2021. Istanbul was divided into seven regions based on ERA5 grid distributions to examine PM 2.5 spatial variability. Seventeen input variables from ERA5, including meteorological, land cover, and vegetation parameters, were analyzed using the Neighborhood Component Analysis (NCA) method to identify the most predictive variables. Comparative analysis showed that while all models provided valuable insights (RF > LGB > XGB > MLR), the NARX model outperformed them, particularly with the complex dataset used. The NARX model achieved a high R-value (0.89), low RMSE (5.24 μg/m³), and low MAE (2.94 μg/m³). It performed best in autumn and winter, with the highest accuracy in Region-1 (R-value 0.94) and the lowest in Region-5 (R-value 0.75). This study's success in a complex urban setting with limited monitoring underscores the robustness of the NARX model and the methodology's potential for global application in similar urban contexts. By addressing temporal and spatial variability in air quality predictions, this research sets a new benchmark and highlights the importance of advanced data analysis techniques for developing targeted pollution control strategies and public health policies., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

A significant concern in our society is the potential impact on both health and the environment of air pollutants released during the incineration of waste. Therefore, it is crucial to conduct thorough control and monitoring measures. In this context, the objective of this research was to study the evolution of particulate matter (PM 2.5 ) and associated trace elements during the period before and after the installation of an Energy Recovery Plant (ERP). For that, a descriptive and temporal analysis of PM 2.5 concentration and composition were performed on two similar areas (impact/control) using the Before-After/Control-Impact (BACI) design and two periods (before from January 01, 2018 to February 06, 2020 and after from December 10, 2020 to September 30, 2022). Results showed a decrease in the levels of PM 2.5 and associated trace elements is observed in the impact zone (IZ) and in the control zone (CZ) throughout the study period. In the case of PM 2.5 , the most notable decrease occurred in the period of the start-up of the ERP, a period that coincides with the confinement and restrictions of COVID, with a subsequent increase in both zones, without reaching the levels observed in the period prior to the start-up of the ERP. Selenium is the only trace element that increases significantly in the IZ. In conclusion, a decrease is observed for all pollutants except selenium in both zones, although less pronounced in the IZ. Since selenium already showed an upward trend in the phase prior to the start of the ERP, it is necessary to investigate its evolution and find out the possible cause., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Jesus Ibarluzea reports financial support was provided by Gipuzkoa Provincial Council. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Background: Regular monitoring of the air pollutant nitrogen dioxide (NO 2 ), an indicator for traffic-related emissions, is a priority in urban environments. The health impacts associated with NO 2 exposure are the result of a combination of factors, including concentration, duration of exposure, and interactions with other pollutants. WHO has established air quality guidelines based on epidemiological studies., Objective: This study develops a new concept "Health Impact Pathways (HIPs)" using adversity as a probabilistic indicator of health effects. For this purpose, it integrates available toxicological and epidemiological information, using Adverse Outcome Pathways (AOPs), in order to understand chemical-biological interactions and their consequences on health., Methods: Literature review and meta-analysis of toxicological data supported by expert judgment were performed to establish: a) adversity pathways, b) quantitative criteria for scoring the observed toxicological effects (adversity indicators), c) NO 2 exposure - adversity relationship for both long-term (1-36 months) and shortterm (1-7 days). The NO 2 daily concentrations from January 2001 to December 2022, were obtained from Madrid city Air Quality network monitoring database. Adversity levels were compared with relative risk levels for all-cause and respiratory mortality estimated using linear equations from WHO 2021 guidelines., Results: Non-linear relations were obtained for all long- and short-term NO 2 related adversity indicators; for long-term effects, the best fitting was obtained with a modified Haber's law model with an exponential coefficient for the exposure time of 0.25. Estimations are presented for a set of case studies for Madrid city, covering temporal and spatial variability. A clear improvement trend along the two decades was observed, as well as high inter- and intra-station variability; the adversity indicators provided integrated information on the temporal and spatial evolution of population level risk., Discussion: The proposed HIP conceptual approach offers promising advances for integrating experimental and epidemiological data. The next step is linking the concentration-adversity relationship with population health impacts through probability estimations, the preliminary estimations confirm the need for assessing independently different population groups., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Instituto de Salud Carlos III. Published by Elsevier Ltd.. All rights reserved.)

The impact of thermally driven mountain-valley breezes (MVB) on the atmospheric environment remains poorly understood, especially in ozone (O 3 )-polluted regions with complex underlying topography. To address this knowledge gap, we focused on the western Sichuan Basin (SCB), situated immediately east of the Tibetan Plateau (TP), which is considered susceptible to MVB coupled with severe O 3 pollution in southwest China. We revealed the MVB driving diurnal O 3 variations and meteorological mechanisms using surface observations and ERA5 reanalysis data. Local MVB days accounted for up to 47% of cases in the summers of 2015-2022. Driven by the MVB, the near-surface O 3 concentrations increased by 8.8%, with 12.7% and 50.0% deterioration in the O 3 light and moderate exceedance rates, respectively, on the western SCB edge. The daytime upslope valley breeze with 20% higher wind speed drove the westward transport of rich O 3 and precursors from the upwind-polluted inner SCB towards its western edge, and the O 3 photochemical production, followed by intensifying solar radiation and air temperature, gave rise to 14.8% of surface O 3 concentrations over the western SCB edge. The nighttime downward mountain breeze with a 20% increase in wind speed could transport the rich O 3 in the mountainous area to the basin edge, causing O 3 levels to increase by 2.8%. In summary, we quantitatively assessed the impacts of MVB on changes in O 3 concentrations and air quality along with its meteorological mechanisms, facilitating a comprehensive understanding of meteorological drivers in the atmospheric environment., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Lignin-based carbon material can be utilized as carbonaceous adsorbents for the removal of toxic gaseous organic pollutants, while the poor heat-resistance limited its widely application. Here in, B-N co-doped lignin carbon (BN-C) with high thermal stability was synthesized, and the optimized BN-C (1:2) exhibited notably improved heat resistance with the decomposition temperature up to 505 °C, and excellent adsorption capacity for o-dichlorobenzene (o-DCB) (1510.0 mg/g) and toluene (947.3 mg/g), together with good cyclic stability over 10 cycles for o-dichlorobenzene. The existence of abundant hexagonal boron nitride (h-BN) with good thermal conductivity contributed to the superior heat-resistance of BN-C (1:2), and the high specific surface area (1764.5 m 2 /g), enriched hydroxyl functional groups and improved graphitization degree contributed to its enhanced adsorption performance. More importantly, BN-C (1:2) supported Ru could effectively remove o-DCB and toluene at wide temperature range (50-300 °C). The present work guided the development of heat-resistant lignin-derived adsorbent-catalyst for gaseous aromatic pollutants removal, which benefits both environmental protection and resource utilization., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Atmospheric pollution has been demonstrated to be associated with ocular surface diseases characterized by corneal epithelial damage, including impaired barrier function and squamous metaplasia. However, the specific mechanisms underlying the impact of atmospheric pollution on corneal damage are still unknow. To address this gap in knowledge, we conducted a study using a whole-body exposure system to investigate the detrimental effects of traffic-related air pollution, specifically diesel exhaust (DE), on corneal epithelium in C57BL/6 mice over a 28-day period. Following DE exposure, the pathological alterations in corneal epithelium, including significant increase in corneal thickness and epithelial stratification, were observed in mice. Additionally, exposure to DE was also shown to disrupt the barrier functions of corneal epithelium, leading to excessive proliferation of basal cells and even causing squamous metaplasia in corneal epithelium. Further studies have found that the activation of yes-associated protein (YAP), characterized by nuclear translocation, may play a significant role in DE-induced corneal squamous metaplasia. In vitro assays confirmed that DE exposure triggered the YAP/β-catenin pathway, resulting in squamous metaplasia and destruction of barrier functions. These findings provide the preliminary evidence that YAP activation is one of the mechanisms of the damage to corneal epithelium caused by traffic-related air pollution. These findings contribute to the knowledge base for promoting eye health in the context of atmospheric pollution., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

The present study examines indoor air pollution in health facilities, focusing on compounds from various sources, such as industrial products, healthcare activities and building materials. It assesses chemical and microbiological concentrations in two public hospitals, two public healthcare centres, and one public health laboratory in Spain. Measurements included indoor air quality, microbiological contaminants, ambient parameters and non-target analysis across ten different locations. Outdoor air quality was also assessed in the surroundings of the hospitals. The results showed that around 350 substances were tentatively identified at a high confidence level, with over 50 % of compounds classified as of high toxicological risk. Three indoor and 26 outdoor compounds were fully confirmed with standards. These confirmed substances were linked to medical, industrial and agricultural activities. Indoor Air Quality (IAQ) results revealed that CO, CO 2 , formaldehyde (HCHO), O 3 and total volatile organic compounds (TVOCs) showed average values above the recommended guideline levels in at least one of the evaluated locations. Moreover, maximum concentrations detected for CO, HCHO, O 3 and TVOCs in hospitals surpassed those previously reported in the literature. SARS-CoV-2 was detected in three air environments, corresponding to COVID-19 patient areas. Fungi and bacteria concentrations were acceptable in all assessed locations, identifying different fungi genera, such as Penicillium, Cladosporium, Aspergillus, Alternaria and Botrytis., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Ammonia (NH 3 ) plays an important role in the formation of atmospheric particulate matter, but the contribution of traffic-related emissions remains unclear, particularly in megacities with a large number of vehicles. Taking the opportunity of the stringent COVID-19 lockdowns implemented in Beijing and Shanghai in 2022, this study aims to estimate the traffic-related NH 3 emissions in these two megacities based on satellite observations. Differences between urban and suburban areas during the lockdown and non-lockdown periods are compared. It was found that despite different dominating sources, the overall NH 3 concentrations in urban and suburban areas were at a similar level, and the lockdown resulted in a more prominent decrease in urban areas, where traffic activities were most heavily affected. The traffic-related contribution to the total emission was estimated to be ∼30% in megacities, and ∼40% in urban areas, which are about 2-10 times higher than that in previous studies. The findings indicate that the traffic-related NH 3 emissions have been significantly underestimated in previous studies and may play a more critical role in the formation of air pollution in megacities, especially in winter, when agricultural emissions are relatively low. This study highlights the importance of traffic-related NH 3 emissions in Chinese megacities and the need to reassess the emissions and their impacts on air quality., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Anthropogenic reactive nitrogen (N) deposition has increased significantly since the industrial revolution. Northern China has become a global hotspot for N deposition. However, few studies have been conducted to quantify the historical changes of atmospheric N deposition fluxes and source contributions in Northern China. By investigating N contents and δ 15 N values of mosses at Mount Tai (Northern China) in 1984 and 2021, we reconstructed fluxes and source contributions of wet inorganic N deposition and evaluated their historical changes. Compared with 1984, moss N contents (from 1.7 ± 0.3% to 2.1 ± 0.4%) showed a significant increase in 2021, which was mainly attributed to a significant increase in nitrate N deposition fluxes at Mount Tai. Moss δ 15 N values (from -5.9 ± 0.9‰ to -5.2 ± 2.4‰) showed a slight increase from 1984 to 2021 at Mount Tai. The importance of combustion-related NH 3 (including vehicle exhaust, coal combustion, and biomass burning) in 2021 (51.2%) were higher than those in 1984 (43.9%), while the importance of volatilization NH 3 sources (including waste and fertilizers) in 2021 (48.8%) were lower than those in 1984 (56.1%). It was fossil-fuel NO x (from vehicle exhaust and coal combustion) (54.1%) rather than non-fossil fuel NO x (from biomass burning and microbial N cycles) (45.9%) dominated NO x emissions in both 1984 and 2021. Our results revealed significant contributions of combustion-related NH 3 and fossil-fuel NO x sources emissions to the elevation of N deposition at Mount Tai in Northern China, which are beneficial for mitigating N emissions and conducting ecological benefit assessments in Northern China., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Biotrickling filter (BTF) is often used for purification of waste gas from swine houses, with vital information still needed regarding interaction effects among multiple gas pollutants removal and also the formation of byproducts especially nitrous oxide (N 2 O, a strong greenhouse gas) due to the relative high NH 3 concentration level compared to other gases. In this study, gas removal and N 2 O production were compared between two BTFs, where the inlet gas of BTF-1 contained NH 3 and H 2 S while p-cresol was additionally supplied to BTF-2. At inlet load (IL) between 3.67 and 18.91 g m -3 h -1 , removal efficiencies of NH 3 exceeded 95% for both BTFs. As alternative strategy, adding thiosulfate improved H 2 S removal. Interestingly, presence of p-cresol to some extent promoted H 2 S removal at IL of 0.56 g m -3 h -1 possibly due to effect on pH value of circulating solution. Similar to NH 3 , removal efficiencies of p-cresol were higher than 95% at an average IL of 2.98 g m -3 h -1 . Gas residence time, pH of circulating solution and inlet loading were identified as key factors affecting BTF performance, but the response of individual gas compound to these factors was not consistent. Overall, p-cresol enhanced N 2 O generation although the effects were not always significant. High-throughput sequencing results showed that Proteobacteria accounted for the largest proportion of relative abundance and BTF-2 had much richer microbial diversity compared to BTF-1. Thermomonas, Comamonas, Rhodanobacter and other bacterial genus capable of denitrification were detected in both BTFs, and their corresponding abundances in BTF-2 (10.9%, 8.7% and 5.2%) were all greater than those in BTF-1 (0.4%, 0.3% and 2.0%), indicating that more denitrification may occur within BTF-2 and higher N 2 O could have been generated. This study provided evidence that organic gas components, served as carbon source, may increase the N 2 O production from BTF when treating waste gases containing NH 3 ., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier Ltd.)

The heterogeneity and complexity of solvent-extracted organic matter associated with PM 2.5 (SEOM-PM 2.5 ) is well known; however, there is scarce information on its biological effects in human cells. This work aimed to evaluate the effect of SEOM-PM 2.5 collected in northern Mexico City during the cold-dry season (November 2017) on NL-20 cells, a human bronchial epithelial cell line. The SEOM obtained accounted for 15.5% of the PM 2.5 mass and contained 21 polycyclic aromatic hydrocarbons (PAHs). The cell viability decreased following exposure to SEOM-PM 2.5 , and there were noticeable morphological changes such as increased cell size and the presence of cytoplasmic vesicles in cells treated with 5-40 μg/mL SEOM-PM 2.5 . Exposure to 5 μg/mL SEOM-PM 2.5 led to several alterations compared with the control cells, including the induction of double-stranded DNA breaks based (p < 0.001); nuclear fragmentation and an increased mitotic index (p < 0.05); 53BP1 staining, a marker of DNA repair by non-homologous end-joining (p < 0.001); increased BiP protein expression; and reduced ATF6, IRE1α, and PERK gene expression. Conversely, when exposed to 40 μg/mL SEOM-PM 2.5 , the cells showed an increase in reactive oxygen species formation (p < 0.001), BiP protein expression (p < 0.05), and PERK gene expression (p < 0.05), indicating endoplasmic reticulum stress. Our data suggest concentration-dependent toxicological effects of SEOM-PM 2.5 on NL-20 cells, including genotoxicity, genomic instability, and endoplasmic reticulum stress., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Long-term exposure to high-level ambient PM 2.5 was associated with increased risks of brain disorders, while the associations remain uncertain when the exposure is lower than current air quality standards in numerous countries. This study aimed to assess the effects of PM 2.5 exposure on the brain system in the population with annual mean concentrations ≤15 μg/m 3 . We analyzed data from 260,922 participants without preexisting brain diseases at baseline in the UK Biobank. The geographical distribution of PM 2.5 in 2010 was estimated by a land use regression model and linked with individual residential address. We investigated associations of ambient PM 2.5 with incident neurological (dementia, Parkinson's diseases [PD], epilepsy, and migraine) and psychiatric (major depressive disorder [MDD] and anxiety disorder) diseases through Cox proportional hazard models. We further estimated the links with brain imaging phenotypes by neuroimaging analysis. Results showed that in the population with PM 2.5 concentrations ≤15 μg/m 3 , each interquartile range (IQR, 1.28 μg/m 3 ) increment in PM 2.5 was related to incidence risks of dementia, epilepsy, migraine, MDD, and anxiety disorder with hazard ratios of 1.08 (95% confidence interval [CI]: 1.03, 1.13), 1.12 (1.05, 1.20), 1.07 (1.00, 1.13), 1.06 (1.03, 1.09), and 1.05 (1.02, 1.08), respectively. We did not observe a significant association with PD. The association with dementia was stronger among the population with poor cardiovascular health (measured by Life's Essential 8) than the counterpart (P for interaction = 0.037). Likewise, per IQR increase was associated with specific brain imaging phenotypes, including volumes of total brain (β = -0.036; 95% CI: -0.050, -0.022), white matter (-0.030; -0.046, -0.014), grey matter (-0.030; -0.042, -0.017), respectively. The findings suggest long-term exposure to ambient PM 2.5 at low-level still has an adverse impact on the neuro-psychiatric systems. The brain-relevant epidemiological assessment suggests that each country should update the standard for ambient PM 2.5 following the World Health Organization Air Quality Guidelines 2021., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Arsenic (As) levels in particulate matter (PM) are routinely monitored in cities of developed countries. Despite advances in the knowledge of its inorganic species in PM in urban areas, organic species are often overlooked with no information on their behaviour in urban parks - areas with increased potential for As biomethylation. Therefore, the aim of this study was to characterize As distribution, bioaccessibility, seasonal variation and speciation (As III , As V , MMA, DMA and TMAO) in PM x -PM 10 of an urban park. Two sites with different distance from the road were selected for winter and summer sampling. From the PM samples, we gravimetrically determined PM 10 concentrations in the air and via ICP-MS the total As content there. To assess the portion of bioaccessible As, water extractable As content was analysed. Simultaneously, the As species in PM 10 water extracts were analysed via coupling of HPLC with ICP-MS method. There was no seasonal difference in PM 10 concentration in the park, probably due to the increased summer PM load related to recreational activities in the park and park design. Spatial distribution of total As in PM 10 and As fractional distribution in PM x suggested that As mostly didn't originate from traffic although highest As content was observed in the fine fraction (PM 2.5 ) related to combustion processes. However, significant winter increase of As (determined by As III and As V ) despite the unchanged concentration of PM 10 indicated a decisive influence of household heating-related combustion and possibly influence of reduced vegetation density. As present in the PM 10 was mostly in bioaccessible form. Seasonal influence of As biomethylation was clearly demonstrated on the TMAO specie during the summer campaign. Except the significant summer TMAO increase, the results also indicated the biomethylation influence on DMA. Therefore, an increased risk of exposure to organic As species in urban parks can be expected during summer., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Elevated ozone (eO 3 ) concentrations pose a threat to insect populations by potentially altering their behaviour and physiology. This study investigates the effects of eO 3 concentrations on the mountain pine beetle which is a major tree-killing species of conifers in northwestern North America. We are particularly interested in understanding the effects of eO 3 concentrations on beetle behaviour and physiology and possible transgenerational impacts on bark beetle broods. We conducted O 3 -enrichment experiments in a controlled laboratory setting using different O 3 concentrations (100-200 ppb; projected for 2050-2100) and assessed various beetle responses, including CO 2 respiration, mating behaviour, survival probability, locomotion, and attraction behaviour. Transgenerational impacts on the first and second generations were also analyzed by studying brood morphology, mating behaviour, survival, and pheromone production. We found that beetles exposed to eO 3 concentrations had shorter oviposition galleries and reduced brood production. Beetle pheromones were also degraded by eO 3 exposure. However, exposure to eO 3 also prompted various adaptive responses in beetles. Despite reduced respiration, eO 3 improved locomotor activity and the olfactory response of beetles. Surprisingly, beetle survival probability was also improved both in the parents and their broods. We also observed transgenerational plasticity in the broods of eO 3 -exposed parents, suggesting potential stress resistance mechanisms. This was evident by similar mating success, oviposition gallery length, and brood numbers produced in both control and eO 3 concentration treatments. This study demonstrates the sensitivity of mountain pine beetles to increased O 3 concentrations, contributing crucial insights into the ecological implications of eO 3 concentrations on their populations. Overall, the outcome of this study contributes to informed climate change mitigation strategies and adaptive management practices for the development of resilient forests in response to emerging forest insect pests worldwide., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

The COVID-19 pandemic has reinforced an interest in the relationship between air pollution and respiratory viral infections, indicating that their burden can be increased under poor air quality. This paper reviews the pathways through which air pollutants can enhance susceptibility to such infections and aggravate their clinical course and outcome. It also summarizes the research exploring the links between various viral infections and exposure to solid and gaseous pollution in Poland, a region characterized by poor air quality, especially during a heating season. The majority of studies focused on concentrations of particulate matter (PM; 86.7%); the other pollutants, i.e., BaP, benzene, CO, NO x , O 3 , and SO 2, were studied less often and sometimes only in the context of a particular infection type. Most research concerned COVID-19, showing that elevated levels of PM and NO 2 correlated with higher morbidity and mortality, while increased PM 2.5 and benzo[a]pyrene levels were related to worse clinical course and outcome in hospitalized, regardless of age and dominant SARS-CoV-2 variant. PM 10 and PM 2.5 levels were also associated with the incidence of influenza-like illness and, along with NO 2 concentrations, with a higher rate of children's hospitalizations due to lower respiratory tract RSV infections. Higher levels of air pollutants also increased hospitalization due to bronchitis (PM, NO x , and O 3 ) and emergency department admission due to viral croup (PM 10 , PM 2.5 , NO x , CO, and benzene). Although the conducted studies imply only correlations and have other limitations, as discussed in the present paper, it appears that improving air quality through reducing combustion processes in energy production in Poland should be perceived as a part of multilayered protection measures against respiratory viral infections, decreasing the healthcare costs of COVID-19, lower tract RSV infections, influenza, and other respiratory viral diseases prevalent between autumn and early spring, in addition to other health and climate benefits., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Background: The individual and combined effects of PM 2.5 constituents on cardiometabolic risk factors are sparsely investigated. Besides, the key cardiometabolic risk factor that PM 2.5 constituents targeted and the biological mechanisms remain unclear., Method: A multistage, stratified cluster sampling survey was conducted in two typically air-polluted Chinese cities. The PM 2.5 and its constituents including sulfate, nitrate, ammonium, organic matter, and black carbon were predicted using a machine learning model. Twenty biomarkers in three category were simultaneously adopted as cardiometabolic risk factors. We explored the individual and mixture association of long-term PM 2.5 constituents with these markers using generalized additive model and quantile-based g-computation, respectively. To minimize potential confounding effects, we accounted for covariates including demographic, lifestyle, meteorological, temporal trends, and disease-related information. We further used ROC curve and mediation analysis to identify the key subclinical indicators and explore whether inflammatory mediators mediate such association, respectively., Result: PM 2.5 constituents was positively correlated with HOMA-B, TC, TG, LDL-C and LCI, and negatively correlated with PP and RC. Further, PM 2.5 constituent mixture was positive associated with DBP, MAP, HbA1c, HOMA-B, AC, CRI-1 and CRI-2, and negative associated with PP and HDL-C. The ROC analysis further reveals that multiple cardiometabolic risk factors can collectively discriminate exposure to PM 2.5 constituents (AUC>0.9), among which PP and CRI-2 as individual indicators exhibit better identifiable performance for nitrate and ammonium (AUC>0.75). We also found that multiple blood lipid indicators may be affected by PM 2.5 and its constituents, possibly mediated through complement C3 or hsCRP., Conclusion: Our study suggested associations of individual and combined PM 2.5 constituents exposure with cardiometabolic risk factors. PP and CRI-2 were the targeted markers of long-term exposure to nitrate and ammonium. Inflammation may serve as a mediating factor between PM 2.5 constituents and dyslipidemia, which enhance current understanding of potential pathways for PM 2.5 -induced preclinical cardiovascular responses., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier Ltd.)

Volatile organic compounds (VOCs) are crucial air pollutants in indoor environments, emitted from building materials, furniture, consumer products, cleaning products, smoking, fuel combustion, cooking, and other sources. VOCs are also emitted from human beings via breath and whole-body skin. Some VOCs cause dermal/ocular irritation as well as gastrointestinal, neurological, cardiovascular, and/or carcinogenic damage to human health. Because people spend most of their time indoors, active control of indoor VOCs has garnered attention. Phytoremediation and microbial remediation, based on plant and microorganism activities, are deemed sustainable, cost-effective, and public-friendly technologies for mitigating indoor VOCs. This study presents the major sources of VOCs in indoor environments and their compositions. Various herbaceous and woody plants used to mitigate indoor VOCs are summarized and their VOCs removal performance is compared. Moreover, this paper reviews the current state of active phytoremediation and microbial remediation for the control of indoor VOCs, and discusses future directions., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Kyung-Suk Cho reports financial support was provided by National Research Foundation of Korea. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Exposure to fine particulate matter (PM 2.5 ) is a significant concern for respiratory health. However, the sources, trigger points, and effect size of specific associations between PM 2.5 components, particularly polycyclic aromatic hydrocarbons (PAHs) and the airway inflammatory marker fractional exhaled nitric oxide (FeNO) have not been fully explored. In this study, 69 healthy college students were enrolled and followed up 16 times from 2014 to 2018. Individual FeNO was measured and ambient air PM 2.5 samples were collected for 7 consecutive days before each follow-up. PAHs were quantified using Gas Chromatography-Mass Spectrometry. Linear mixed-effect regression models were employed to evaluate the associations between PM 2.5 -bound PAHs and FeNO. Additionally, PMF (Positive Matrix Factorization) was utilized to identify sources of PM 2.5 -bound PAHs and assess their impact on FeNO. Throughout the study, the average (SD) of ΣPAHs concentrations was 78.50 (128.9) ng/m 3 . PM 2.5 and PM 2.5 -bound PAHs were significantly associated with FeNO at various lag days. Single-day lag analyses revealed maximum effects of PM 2.5 on FeNO, with an increase of 7.71% (95% CI: 4.67%, 10.83%) per interquartile range (IQR) (48.10 μg/m 3 ) increase of PM 2.5 at lag2, and ΣPAHs showed a maximum elevation in FeNO of 6.40% (95% CI: 2.33%, 10.63%) at lag4 per IQR (57.39 ng/m 3 ) increase. Individual PAHs exhibited diversity peak effects on FeNO at lag3 (6 of 17), lag4 (9 of 17) in the single-day model, and lag0-5 (8 of 17) (from lag0-1 to lag0-6) in the cumulative model. Source apportionment indicated coal combustion as the primary contributor (accounting for 30.7%). However, a maximum effect on FeNO (an increase of 21.57% (95% CI: 13.58%, 30.13%) per IQR increase) was observed with traffic emissions at lag4. The findings imply that strategic regulation of particular sources of PAHs, like traffic emissions, during specific periods could significantly contribute to safeguarding public health., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Burning incenses and scented candles may provide harmful chemicals. Although many studies have evaluated volatile organic chemicals emitted by their use and related health risks, extension of our understanding for guiding appropriate use under various use conditions is necessary. In this study, emission characteristics of commercial incenses and scented candles were evaluated in a laboratory chamber using real-time measurement and the time-weighted average exposure concentrations of monoaromatic compounds and monoterpenes were assessed using passive samplers while volunteers living in a studio apartment use them. After burning incense, the average levels of benzene increased from 1.4 to 100 μg m -3 . The presence of a wood core in commercial incense products was the main cause of high benzene emission by burning them although the increase in benzene was also influenced by factors such as the brand of the products, the number of incense sticks burned, the duration of each burning session, and ventilation period. Electrical warming of scented candles increased the levels of monoterpenes by factors of 16-30 on average. Considering the emission characteristics found in this study, exposure to benzene and monoterpenes could be mitigated by cautious use of those products in residential areas., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

In the electrical industry, there are many hazardous gases that pollute the environment and even jeopardize human health, so timely detection and effective control of these hazardous gases is of great significance. In this work, the gas-sensitive properties of Pd-modified g-C 3 N 4 interface for each hazardous gas molecule were investigated from a microscopic viewpoint, taking the hazardous gases (CO, NO x ) that may be generated in the power industry as the detection target. Then, the performance of Pd-modifiedg-C 3 N 4 was evaluated for practical applications as a gas sensor material. Novelly, an unconventional means was designed to briefly predict the effect of humidity on the adsorption properties of this sensor material. The final results found that Pd-modified g-C 3 N 4 is most suitable as a potential gas-sensitizing material for NO 2 gas sensors, followed by CO. Interestingly, Pd-modified g-C 3 N 4 is less suitable as a potential gas-sensitizing material for NO gas sensors, but has the potential to be used as a NO cleaner (adsorbent). Unconventional simulation explorations of humidity effects show that in practical applications Pd-modified g-C 3 N 4 remains a promising material for gas sensing in specific humidity environments. This work reveals the origin of the excellent properties of Pd-modified g-C 3 N 4 as a gas sensor material and provides new ideas for the detection and treatment of these three hazardous gases., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Pengfei Jia reports financial support was provided by Open Research Fund Program of Data Recovery Key Laboratory of Sichuan Province; Changyou Ma reports financial support was provided by Neijiang basic research and applied basic research project; Pengfei Jia reports financial support was provided by National Natural Science Foundation of China; Pengfei Jia reports financial support was provided by Sichuan Province Science and Technology Support Program; Dachang Chen reports financial support was provided by Natural Science Foundation of Hubei Province. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Background: Little is known about the relationship between long-term joint exposure to mixtures of air pollutants and the prevalence of chronic obstructive pulmonary disease (COPD). We aimed to assess the joint impact of long-term exposure to ambient air pollution on the prevalence of COPD in Korea, especially in areas with high levels of air pollution., Methods: We included 22,387 participants who underwent spirometry tests in 2010-2019. The community multiscale air quality model was used to estimate the levels of ambient air pollution at residential addresses. The average exposure over the 5 years before the examination date was used to calculate the concentrations of air pollution. Forced expiratory volume in 1 s and forced vital capacity were used to define restrictive lung disease, COPD, and moderate-to-severe COPD. Quantile-based g-computation models were used to assess the joint impact of air pollution on COPD prevalence., Results: A total of 2535 cases of restrictive lung disease, 2787 cases of COPD, and 1399 cases of moderate-to-severe COPD were identified. In the individual pollutant model, long-term exposure was significantly associated with both restrictive lung disease and COPD. In the mixture pollutant model, the odds ratios (ORs, 95% confidence intervals) for restrictive lung disease increased with each quartile increment in the 1- to 5-year average mixtures: 1.14 (1.02-1.28, 1 year), 1.25 (1.11-1.41, 2 years), 1.26 (1.11-1.42, 3 years), 1.32 (1.16-1.51, 4 years), and 1.37 (1.19-1.58, 5 years), respectively. The increase in ORs of restrictive lung disease accelerated over time. By contrast, the ORs of COPD showed a decreasing trend over time., Conclusions: Long-term exposure to air pollutants, both individually and jointly, was associated with an increased risk of developing COPD, particularly restrictive lung disease. Our findings highlight the importance of comprehensively assessing exposure to various air pollutants in relation to COPD., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier Ltd.)

Per- and polyfluoroalkyl substances (PFAS) are a unique class of chemicals synthesized to aid in industrial processes, fire-fighting products, and to benefit consumer products such as clothing, cosmetics, textiles, carpets, and coatings. The widespread use of PFAS and their strong carbon-fluorine bonds has led to their ubiquitous presence throughout the world. Airborne transport of PFAS throughout the atmosphere has also contributed to environmental pollution. Due to the potential environmental and human exposure concerns of some PFAS, research has extensively focused on water, soil, and organismal detection, but the presence of PFAS in the air has become an area of growing concern. Methods to measure polar PFAS in various matrices have been established, while the investigation of polar and nonpolar PFAS in air is still in its early development. This literature review aims to present the last two decades of research characterizing PFAS in outdoor and indoor air, focusing on active and passive air sampling and analytical methods. The PFAS classes targeted and detected in air samples include fluorotelomer alcohols (FTOHs), perfluoroalkane sulfonamides (FASAs), perfluoroalkane sulfonamido ethanols (FASEs), perfluorinated carboxylic acids (PFCAs), and perfluorinated sulfonic acids (PFSAs). Although the manufacturing of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) has been largely phased out, these two PFAS are still often detected in air samples. Additionally, recent estimates indicate that there are thousands of PFAS that are likely present in the air that are not currently monitored in air methods. Advances in air sampling methods are needed to fully characterize the atmospheric transport of PFAS., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Published by Elsevier Ltd.)

Globally, air pollution is an unfortunate aftermath of rapid industrialization and urbanization. Although the best strategy is to prevent air pollution, it is not always feasible. This makes it imperative to devise and implement techniques that can clean the air continuously. Plants and microbes have a natural potential to transform or degrade pollutants. Hence, strategies that use this potential of living biomass to remediate air pollution seem to be promising. The simplest future trend can be planting suitable plant-microbe species capable of removing air pollutants like SO 2 , CO 2 , CO, NO X and particulate matter (PM) along roadsides and inside the buildings. Established wastewater treatment strategies such as microbial fuel cells (MFC) and constructed wetlands (CW) can be suitably modified to ameliorate air pollution. Green architecture involving green walls and green roofs is facile and aesthetic, providing urban ecosystem services. Certain microbe-based bioreactors such as bioscrubbers and biofilters may be useful in small confined spaces. Several generative models have been developed to assist with planning and managing green spaces in urban locales. The physiological limitations of using living organisms can be circumvent by applying biotechnology and transgenics to improve their potential. This review provides a comprehensive update on not just the plants and associated microbes for the mitigation of air pollution, but also lists the technologies that are available and/or can be modified and used for air pollution control. The article also gives a detailed analysis of this topic in the form of strengths-weaknesses-opportunities-challenges (SWOC). The strategies mentioned in this review would help to attain corporate Environmental Social and Governance (ESG) and Sustainable Development Goals (SDGs), while reducing carbon footprint in the urban scenario. The review aims to emphasise that urbanization is possible while tackling air pollution using facile, green techniques involving plants and associated microbes., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Open biomass burning (BB) events are a well-known primary aerosol source, resulting in the emission of significant amount of gaseous and particulate matter and affecting Earth's radiation budget. The 2019-2020 summer, known as "Australian Black Summer", showed exceptional duration and intensity of seasonal wildfires, triggered by high temperatures and severe droughts. Since increasing megafires are predicted due to expected climate changes, it is critical to study the impact of BB aerosol on a large scale and evaluate related transport processes. In this study, five aerosol samples (total suspended particles with a diameter >1 μm) were collected during the XXXV Italian Expedition in Antarctica on board of the R/V Laura Bassi from 6th of January to February 16, 2020, along the sailing route from Lyttelton harbor (New Zealand) to Terra Nova Bay (Antarctica). Levoglucosan and its isomers have been analyzed as markers of BB, together with polycyclic aromatic hydrocarbons (PAHs), sucrose and alcohol sugars. Ionic species and carboxylic acids have been analyzed to support the identification of aerosol sources and its aging. Results showed high levoglucosan concentrations (325-1266 pg m -3 ) during the campaign, suggesting the widespread presence of smoke in the region, because of huge wildfire releases. Backward trajectories indicated the presence of long-range atmospheric transport from South America, probably carrying wildfires plume, in agreement with literature. Regional sources have been suggested for PAHs, particularly for 3-4 rings' compounds; monosaccharides, sucrose, arabitol, and mannitol were related to marine and biogenic contributions. In a warming climate scenario, more frequent and extensive wildfire episodes are expected in Australia, potentially altering albedo, aerosol radiative properties, and cloud interactions. Therefore, it is crucial to strengthens the investigations on the regional climatic effects of these events in Antarctica., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

The former mining district of Salsigne is situated in the Orbiel valley. Until the 20th century, it was the first gold mine in Europe and the first arsenic mine in the world. Rehabilitation has been performed during the 20 years that followed closure of the mines and factories, which led to the accumulation of storage of several million tons of waste in this valley. Nevertheless, a detailed description of the air quality of this area is still missing. The goal of the present study is to evaluate atmospheric contamination in the valley and identify the potential sources of this contamination. Active monitors (particulate matter samplers) and passive bioindicators (Tillandsia usneoides) were placed in strategic sites including remote areas. Over the year 2022, we assessed the air quality using microscopic and spectroscopic techniques, as well as environmental risk indicators to report the level of contamination. Results indicate that the overall air quality in the valley is good with PM 10 levels in accordance with EU standards. Elemental concentrations in the exposed plants were lower than reported in the literature. Among the different sites studied, Nartau and La Combe du Saut, corresponding to waste storage and former mining industry sites, were the most affected. Chronic exposure over 1 year was highlighted for Fe, Ni, Cu, Pb, Sb and As. Pollution Load Index and Enrichment Factors, which provided valuable information to assess the environmental condition of the valley's air, suggested that dust and resuspension of anthropogenic materials were the principle sources for most of the elements. Finally, this study also highlights that using T. usneoides could be a convenient approach for biomonitoring of metal (loid)-rich particles in the atmosphere within a former mining area, for at least one year. These results in turn allow to better understand the effects of chronic exposure on the ecosystem., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier Ltd.)

The devastating effects of COVID-19 pandemic have widely affected human lives and economy across the globe. There were significant changes in the global environmental conditions in response to the lockdown (LD) restrictions made due to COVID-19. The direct impact of LD on environment is analysed widely across the latitudes, but its secondary effect remains largely unexplored. Therefore, we examine the changes in particulate matter (PM₂.₅) during LD, and its impact on the global croplands. Our analysis finds that there is a substantial decline in the global PM₂.₅ concentrations during LD (2020) compared to pre-lockdown (PreLD: 2017-2019) in India (10-20%), East China (EC, 10%), Western Europe (WE, 10%) and Nigeria (10%), which are also the cropland dominated regions. Partial correlation analysis reveals that the decline in PM₂.₅ positively affects the cropland greening when the influence of temperature, precipitation and soil moisture are limited. Croplands in India, EC, Nigeria and WE became more greener as a result of the improvement in air quality by the reduction in particulates such as PM₂.₅ during LD, with an increase in the Enhanced Vegetation Index (EVI) of about 0.05-0.1, 0.05, 0.05 and 0.05-0.1, respectively. As a result of cropland greening, increase in the total above ground biomass production (TAGP) and crop yield (TWSO) is also found in EC, India and Europe. In addition, the improvement in PM₂.₅ pollution and associated changes in meteorology also influenced the cropland phenology, where the crop development stage has prolonged in India for wet-rice (1-20%) and maize (1-10%). Therefore, this study sheds light on the response of global croplands to LD-induced improvements in PM₂.₅ pollution. These finding have implications for addressing issues of air pollution, global warming, climate change, environmental conservation and food security to achieve the Sustainable Development Goals (SDGs)., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Short-chain and medium-chain chlorinated paraffins (SCCPs and MCCPs) have garnered significant attention because they have persistence and potential toxicity, and can undergo long-distance transport. Chlorinated paraffins (CPs) inhaled in the size-fractionated particulate phase and gas phase can carry different risks to human health due to their ability to accumulate in different regions of the respiratory tract and exhibit varying deposition efficiencies. In our study, large-volume ambient air samples in both the size-fractionated particulate phase (Dp < 1.0 μm, 1.0-2.5 μm, 2.5-10 μm, and Dp ≥ 10 μm) and gas phase were collected simultaneously in Beijing using an active sampler. The overall levels of SCCPs and MCCPs were relatively high, the ranges being 57-881 and 30-385 ng/m 3 , respectively. SCCPs tended to be partitioned in the gas phase (on average 75% of the ΣSCCP concentration), while MCCPs tended to be partitioned in the particulate phase (on average 62% of the ΣMCCP concentration). Significant correlations were discovered between the logarithm-transformed gas-particle partition coefficients (K P ) and predicted subcooled vapor pressures (P L 0 ) (p < 0.01 for SCCPs and MCCPs) and between the logarithm-transformed K P values and octanol-air partition coefficients (K OA ) (p < 0.01 for SCCPs and MCCPs). Thus, the slopes indicated that organic matter absorption was the dominant process involved in gas-particle partitioning. We used the ICRP model to calculate deposition concentrations for particulate-associated CPs in head airways region (15.6-71.4 ng/m³), tracheobronchial region (0.8-4.8 ng/m³), and alveolar region (5.1-21.9 ng/m³), then combined these concentrations with the CP concentrations in the gas phase to calculate estimated daily intakes (EDIs) for inhalation. The EDIs for SCCPs and MCCPs through inhalation of ambient air for the all-ages group were 67.5-184.2 ng/kg/day and 19.7-53.7 ng/kg/day, respectively. The results indicated that SCCPs and MCCPs in ambient air do not currently pose strong risks to human health in the study area., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

The concentration of polycyclic aromatic hydrocarbons (PAHs) in the air inside residential houses in Iran along with measuring the amount of 1-OHpyrene metabolite in the urine of the participants in the study was investigated by gas chromatography-mass spectrometry (GC-MS). Demographic characteristics (including age, gender, and body composition), equipment affecting air quality, and wealth index were also investigated. The mean ± standard error (SE) concentration of particulate matter 10 (PM 10 ) and ∑PAHs in the indoor environment was 43.2 ± 1.98 and 1.26 ± 0.15 μg/m 3 , respectively. The highest concentration of PAHs in the indoor environment in the gaseous and particulate phase related to Naphthalene was 1.1 ± 0.16 μg/m 3 and the lowest was 0.01 ± 0. 0.001 μg/m 3 Pyrene, while the most frequent compounds in the gas and particle phase were related to low molecular weight hydrocarbons. 30% of the samples in the indoor environment have BaP levels higher than the standards provided by WHO guidelines. 68% of low molecular weight hydrocarbons were in the gas phase and 73 and 75% of medium and high molecular weight hydrocarbons were in the particle phase. There was a significant relationship between the concentration of some PAH compounds with windows, evaporative coolers, printers, and copiers (p < 0.05). The concentration of PAHs in houses with low economic status was higher than in houses with higher economic status. The average concentration of 1-hydroxypyrene metabolite in the urine of people was 7.10 ± 0.76 μg/L, the concentration of this metabolite was higher in men than in women, and there was a direct relationship between the amount of this metabolite in urine and the amount of some hydrocarbon compounds in the air, PM 10 , visceral fat and body fat. This relationship was significant for age (p = 0.01). The concentration of hydrocarbons in the indoor environment has been above the standard in a significant number of non-smoking indoor environments, and the risk assessment of these compounds can be significant. Also, various factors have influenced the amount of these compounds in the indoor air, and paying attention to them can be effective in reducing these hydrocarbons in the air., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier Ltd.)

Due to the increasing evidence of widespread sub-micron pollutants in the atmosphere, the impact of airborne nanoparticles is a subject of great relevance. In particular, the smallest particles are considered the most active and dangerous, having a higher surface/volume ratio. Here we tested the effect of iron oxide (Fe 3 O 4 ) nanoparticles (IONPs) with different mean diameter and size distribution on the model plant Tillandsia usneoides. Strands were placed in home-built closed boxes and exposed to levels of airborne IONPs reported for the roadside air, i.e. in the order of 10 7 - 10 8 items m -2 . Plant growth and other morpho-physiological parameters were monitored for two weeks, showing that exposure to IONPs significantly reduced the length increment of the treated strands with respect to controls. A dose-dependence of this impairing effect was found only for particles with mean size of a few tens of nanometers. These were also proved to be the most toxic at the highest concentration tested. The IONP-induced hamper in growth was correlated with altered concentration of macro- and micronutrients in the plant, while no significant variation in photosynthetic activity was detected in treated samples. Microscopy investigation showed that IONPs could adhere to the plant surface and were preferentially located on the trichome wings. Our results report, for the first time, evidence of the negative effects of airborne IONP pollution on plant health, thus raising concerns about related environmental risks. Future research should be devoted to other plant species and pollutants to assess the impact of airborne pollution on plants and devise suitable attenuation practices., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Sara Falsini, Ilaria Colzi, Marco Dainelli reports financial support was provided by Ministry of Education and Merit. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Published by Elsevier Ltd.)