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Start Over Author "Sala M" Journal clinica chimica acta
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7. Spheroplasts, poorly known but clinically relevant particles of urinary sediment

Author

Rosanna Falbo, Valerio Leoni, Maria Roberta Sala, Giuseppe Garigali, Paolo Brambilla, Giovanni B. Fogazzi, Adela Sulejmani, Falbo, R, Fogazzi, G, Sala, M, Garigali, G, Sulejmani, A, Brambilla, P, and Leoni, V

Subjects
0301 basic medicine, medicine.medical_specialty, Erythrocytes, Urinalysis, medicine.drug_class, SediMAX, Clinical Biochemistry, Antibiotics, Spheroplasts, Urine, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Urinary sediment, Internal medicine, medicine, Humans, Urine sediment, ß-lactam antibiotic, medicine.diagnostic_test, business.industry, Communication, Urinalysi, fungi, Biochemistry (medical), Spheroplast, General Medicine, 030104 developmental biology, 030220 oncology & carcinogenesis, business
Abstract

Background In two patients under treatment with various antibiotics, spheroplasts were detected with an automated urine sediment analyzer. Methods Urinalysis was performed by an AutionMAX AX 4030-sediMAX platform. Results Spheroplasts can be easily misclassified as yeasts or erythrocytes, but when automated urine sediment analyzers are used by well-trained, and experienced operators they can be correctly identified and classified. Conclusion Appropriate training of urine laboratory professionals in spheroplast detection and association with UTI, together with timely communication with the microbiologist and caring clinician, will provide prompt targeted treatment.

Published
2021
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