1. Emolienty w leczeniu schorzeń dermatologicznych: stanowisko grupy ekspertów.
- Author
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Szepietowski, Jacek, Kaszuba, Andrzej, Adamski, Zygmunt, Placek, Waldemar, and Salomon, Joanna
- Subjects
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ANTISEPTICS , *OINTMENTS , *EPIDERMIS , *LIPIDS , *PEPTIDES - Abstract
Emollients are topical agents with moisturizing, lubricating and smoothing properties. The most important action of emollients is restoring the disturbed epidermal barrier. This effect is achieved by various mechanisms: occlusive properties, attraction and keeping the water within the stratum corneum and supplying the physiological lipids and peptides, that lack in the disturbed epidermis. The final effects of emollients are reduction of inflammation, decrease of pruritus and better appearance of the skin. Emollients are the essential part of the therapy of many inflammatory skin diseases with disturbed epidermal barrier. They are used in the treatment of atopic dermatitis, psoriasis, keratinization disorders, chronic eczema, pruritic diseases and many other dermatoses. Emollients are often the adjuvant therapy, which is used together with topical corticosteroids or calcineurin inhibitors. There are several possible types of therapy: continuous, intermittent or proactive. This paper summarizes the knowledge about emollients, their mechanisms of action, the indications and proper way of application. [ABSTRACT FROM AUTHOR]
- Published
- 2011