1. Etiology of Bacterial Meningitis Among Children <5 Years Old in Côte d’Ivoire: Findings of Hospital-based Surveillance Before and After Pneumococcal Conjugate Vaccine Introduction
- Author
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Flore Sandrine Zaba, Catherine Boni-cisse, Jason M. Mwenda, Bernard Ntsama, Alice Britoh-Mlan, Effua Usuf, Brenda Kwambana-Adams, Joseph Nsiari-Muzeyi Biey, Martin Antonio, Sheikh Jarju, Peter Sylvanus Ndow, N'zue Kofi, Nicaise Aka Lepri, Rowan E Bancroft, Archibald Worwui, and Hamidou Kone
- Subjects
Male ,0301 basic medicine ,Microbiology (medical) ,Serotype ,medicine.medical_specialty ,030106 microbiology ,Supplement Articles ,Neisseria meningitidis ,Hospitals, General ,World Health Organization ,medicine.disease_cause ,Pneumococcal conjugate vaccine ,Meningitis, Bacterial ,Haemophilus influenzae ,Pneumococcal Vaccines ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Streptococcus pneumoniae ,Epidemiology ,Prevalence ,medicine ,Humans ,030212 general & internal medicine ,Serotyping ,Vaccines, Conjugate ,business.industry ,Côte d’Ivoire ,Haemophilus influenzae type b ,Infant, Newborn ,meningitis ,Infant ,medicine.disease ,pediatric ,Cote d'Ivoire ,Infectious Diseases ,Pneumococcal vaccine ,Child, Preschool ,Female ,business ,pneumococcus ,Sentinel Surveillance ,Meningitis ,medicine.drug - Abstract
Background Bacterial meningitis remains a major disease affecting children in Côte d’Ivoire. Thus, with support from the World Health Organization (WHO), Côte d’Ivoire has implemented pediatric bacterial meningitis (PBM) surveillance at 2 sentinel hospitals in Abidjan, targeting the main causes of PBM: Streptococcus pneumoniae (pneumococcus), Haemophilus influenzae, and Neisseria meningitidis (meningococcus). Herein we describe the epidemiological characteristics of PBM observed in Côte d’Ivoire during 2010–2016. Methods Cerebrospinal fluid (CSF) was collected from children aged, Longitudinal sentinel surveillance at 2 hospitals within Abidjan, Côte d’Ivoire, during 2010–2016 revealed that Streptococcus pneumoniae was the predominant pathogen responsible for pediatric bacterial meningitis before and after the introduction of the 13-valent pneumococcal conjugate vaccine.
- Published
- 2019
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