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Start Over Author "Stefanescu, Horia" Journal clinics and research in hepatology and gastroenterology
3 results on '"Stefanescu, Horia"'

3. Comparison of screening strategies with two new tests to score and diagnose varices needing treatment

Author

Paul Calès, Federico Ravaioli, Arthur Berger, Oana Farcau, Davide Festi, Horia Stefanescu, Carole Vitellius, Pierre Nahon, Christophe Bureau, Nathalie Ganne-Carriè, Annalisa Berzigotti, Victor de Ledinghen, Salvatore Petta, Calès, Paul, Ravaioli, Federico, Berger, Arthur, Farcau, Oana, Festi, Davide, Stefanescu, Horia, Vitellius, Carole, Nahon, Pierre, Bureau, Christophe, Ganne-Carriè, Nathalie, Berzigotti, Annalisa, de Ledinghen, Victor, and Petta, Salvatore

Subjects
Liver Cirrhosis, Hepatology, Non-invasive test, Platelet Count, Gastroenterology, Esophageal and Gastric Varices, Varicose Veins, Elastometry, Non-alcoholic Fatty Liver Disease, Oesophageal varice, Screening, Elasticity Imaging Techniques, Humans, Portal hypertension, Retrospective Studies
Abstract

Background and aims: We aimed to improve non-invasive screening of varices needing treatment (VNT) and compare different screening strategies. Methods: 2,290 patients with chronic liver disease were included in a retrospective study. Etiologies were: virus: 50.0%, NAFLD: 29.5%, alcohol: 20.5%, VNT: 14.9%. Test descriptors were performance (spared endoscopy) and safety (missed VNT). VNT tests were evaluated according to their safety levels either for individual screening (95% negative predictive value (NPV)), population screening (95% sensitivity) or undifferentiated screening (100% sensitivity/NPV) without missed VNT. The tests provided three categories: missed VNT

Published
2022

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