1. The relationship between red cell aging and enzyme activities in experimental animals.
- Author
-
Shimizu Y and Suzuki M
- Subjects
- Acetylcholinesterase blood, Animals, Aspartate Aminotransferases blood, Cricetinae, Erythrocytes physiology, Glucosephosphate Dehydrogenase blood, Guinea Pigs, Hexokinase blood, L-Lactate Dehydrogenase blood, Mesocricetus, Mice, Mice, Inbred Strains, Phosphogluconate Dehydrogenase blood, Rabbits, Rats, Rats, Inbred Strains, Species Specificity, Erythrocyte Aging, Erythrocytes enzymology
- Abstract
1. The relationship between red cell aging and enzyme activities was studied in rabbit, guinea-pig, hamster, rats (F344/N and SD), and mice (BALB/c and DBA/2). 2. The activities of six enzymes: glucose-6-phosphate dehydrogenase (G-6-PD), 6-phosphogluconate dehydrogenase (6-PGD), hexokinase (Hx), glutamate oxaloacetate transminase (GOT), lactate dehydrogenase (LDH) and acetylcholinesterase (AChE), were measured in the red cells of different ages which were obtained either by centrifugation or experimental anaemia. 3. Hx, AChE and GOT activities were much higher in younger red cells than in older cells, hence the activities of these enzymes may be used as an indicator of age of the cells.
- Published
- 1991
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