1. Non-islet Cell Tumor-induced Hypoinsulinemic Hypoglycemia in the Setting of Metastatic Desmoplastic Round Cell Tumor
- Author
-
Nadir Bhuiyan and Purva Sharma
- Subjects
medicine.medical_specialty ,Weakness ,endocrine system diseases ,medicine.medical_treatment ,Recurrent hypoglycemia ,desmoplastic round cell tumor ,Cell ,Hypoglycemia ,paraneoplastic syndrome ,Gastroenterology ,Refractory ,Internal medicine ,Internal Medicine ,medicine ,non-islet cell tumor induced hypoglycemia ,Chemotherapy ,geography ,geography.geographical_feature_category ,business.industry ,General Engineering ,nutritional and metabolic diseases ,medicine.disease ,Islet ,tumor induced hypoglycemia ,medicine.anatomical_structure ,Medical Education ,Oncology ,Round cell tumor ,medicine.symptom ,business - Abstract
A 24-year-old male with metastatic desmoplastic round cell tumor was admitted for fatigue and weakness after chemotherapy. The patient was found to be hypotensive, pancytopenic, and bacteremic. Early treatment with intravenous antibiotics and fluids was efficacious. The hospital course was complicated by recurrent hypoglycemia that was refractory to the standard hypoglycemia protocol. Initial workup revealed low serum insulin and normal C-peptide. Further evaluation revealed elevated IGF-II levels consistent with non-islet cell tumor-induced hypoglycemia. Euglycemia was subsequently achieved with aggressive and continuous infusion of intravenous 10% dextrose.
- Published
- 2019