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1. Regeneration Tensed Up: Polyploidy Takes the Lead.

Author

Spiró Z and Heisenberg CP

Subjects
Animals, Heart, Polyploidy, Zebrafish Proteins genetics, Regeneration, Zebrafish
Abstract

The cellular mechanisms allowing tissues to efficiently regenerate are not fully understood. In this issue of Developmental Cell, Cao et al. (2017) discover that during zebrafish heart regeneration, epicardial cells at the leading edge of regenerating tissue undergo endoreplication, possibly due to increased tissue tension, thereby boosting their regenerative capacity., (Copyright © 2017. Published by Elsevier Inc.)

Published
2017
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