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Your search keyword '"MALDI TOF MS"' showing total 2 results
Start Over Descriptor "MALDI TOF MS" Journal ghana medical journal
2 results on '"MALDI TOF MS"'

1. Evaluation of Matrix-assisted laser desorption/ionization Time-of flight Mass spectrometry (MALDI TOF MS) and VITEK 2 in routine microbial identification.

Author

Madhavan, Anitha, Sachu, Arun, Sethuraman, Nandini, Kumar, Anil, and Vasudevapanicker, Jayalakshmi

Subjects
*MASS spectrometry, *DESORPTION, *TURNAROUND time, *MEDICAL microbiology, *ERROR rates
Abstract

Bacground: Microbial Identification was done by phenotypic methods. VITEK-2 and Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) are now being increasingly used in laboratories. Objectives: To compare and evaluate the usefulness of MALDI-TOF MS and VITEK-2 in routine microbial identification. Methods: The performances of MALDI-TOF MS and VITEK 2 were compared for identifying microorganisms. Results: MALDI-TOF MS and VITEK-2 correctly identified 96 % (96/100) and 97% (97/100) of the isolates upto the genus level. Conclusion: MALDI TOF MS and VITEK -2 gave comparable identification and error rates. The rapid reduction in turnaround time with MALDI TOF is a significant game-changer in the field of clinical microbiology. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
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2. Evaluation of Matrix-assisted laser desorption/ionization Time-of flight Mass spectrometry (MALDI TOF MS) and VITEK 2 in routine microbial identification

Author

Anitha, Madhavan, Arun, Sachu, Nandini, Sethuraman, Anil, Kumar, and Jayalakshmi, Vasudevapanicker

Subjects
fluids and secretions, VITEK -2, Lasers, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Humans, Sequencing, MALDI TOF MS
Abstract

Background: Microbial Identification was done by phenotypic methods. VITEK-2 and Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) are now being increasingly used in laboratories.Objectives: To compare and evaluate the usefulness of MALDI-TOF MS and VITEK-2 in routine microbial identification.Methods: The performances of MALDI-TOF MS and VITEK 2 were compared for identifying microorganisms.Results: MALDI- TOF MS and VITEK-2 correctly identified 96 % (96/100) and 97% (97/100) of the isolates upto the genus level.Conclusion: MALDI TOF MS and VITEK -2 gave comparable identification and error rates. The rapid reduction in turnaround time with MALDI TOF is a significant game-changer in the field of clinical microbiology

Published
2021
Full Text
View/download PDF

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