Search

A patent application titled "A Coronary Artery Disease Analysis System" was published online by inventors from Australia, with Artrya Limited as the assignee. The system aims to analyze patient CT scan data to identify and characterize coronary artery disease, including stenosis lesions, vulnerable plaque, and plaque type, using a user-friendly interface. The system provides visual indications and detailed information to help users assess and understand individual stenosis lesions, aiding in the prevention and management of heart diseases. The application includes detailed claims and descriptions of the CAD analysis system's features and functionalities. [Extracted from the article]

A recent study conducted at the National Institute of Cardiology Ignacio Chavez in Mexico City explored the impact of wood smoke exposure on aortic valve mineralization in patients with coronary stenosis. The research found that individuals exposed to wood smoke exhibited more extensive lesion characteristics compared to those with no exposure, indicating a potential link between chronic wood smoke exposure and structural damage in aortic valve tissue. The study highlights the role of environmental factors, such as wood smoke, in contributing to cardiovascular health deterioration. For more information, the full article can be accessed in the Journal of Clinical Medicine. [Extracted from the article]

Researchers at the Department of Endocrinology conducted a study on the predictive value of the systemic immune-inflammation index (SII) for the severity of coronary stenosis in patients with coronary heart disease and diabetes mellitus. The study involved 2760 patients with cardiovascular disease and found that higher SII values were associated with a greater likelihood of developing complex coronary artery lesions in diabetic patients with CHD. The research concluded that SII levels can serve as an independent predictor of the severity of coronary plaque burden in diabetic patients with CHD, aiding clinicians in refining risk stratification and implementing personalized management strategies. [Extracted from the article]

A recent study conducted by researchers at Chongqing University explored the relationship between clonal hematopoiesis of indeterminate potential (CHIP) and the severity of coronary artery lesions in coronary heart disease (CHD) patients with renal insufficiency. The study involved 70 CHD patients with renal insufficiency and found that CHIP was associated with a higher severity of coronary artery disease. This research suggests that CHIP may be an independent risk factor for severe coronary artery disease in CHD patients with renal insufficiency. [Extracted from the article]

A recent study conducted at Fuwai Hospital in Beijing, China, explored the use of Myocardial Contrast Echocardiography (MCE) to diagnose functionally significant coronary disease. The researchers compared the perfusion index (PI) from MCE with the quantitative flow ratio (QFR) as a gold standard for diagnosis. The study found that PI derived from MCE can effectively diagnose functionally significant coronary disease, with the left anterior descending artery PI showing the highest diagnostic efficiency. This research provides valuable insights into non-invasive diagnostic techniques for heart disease. [Extracted from the article]

Researchers at a Radiology Department discussed a case of Takayasu's arteritis causing coronary stenosis with myocardial ischemia, severe aortic regurgitation, and pericarditis. The study emphasized the importance of early diagnosis and multimodal imaging in managing this rare large-vessel vasculitis that can lead to severe cardiac complications. The case study highlighted the need to consider Takayasu's arteritis in patients with atypical clinical features and cardiac involvement, particularly in cases with valvular disease. For more information, readers can refer to the Radiology Case Reports journal article. [Extracted from the article]

A study from Warsaw, Poland, focused on a 38-year-old man with a history of hypertension and smoking who experienced a heart attack without significant coronary artery blockages. The diagnosis was myocardial infarction with non-obstructive coronary artery disease (MINOCA), attributed to vasospastic angina. Treatment involved medication adjustments and lifestyle changes to prevent future episodes. The research highlights the importance of considering vasoconstrictive origins in cases of MINOCA. [Extracted from the article]

A study conducted by Army Medical University researchers in Chongqing, China, focused on the differences in severity of diffuse and focal coronary stenosis between visual and quantitative assessment methods. The research found that physician visual assessment tended to overestimate diameter stenosis in coronary arteries compared to quantitative coronary angiography, with diffuse stenosis being more likely to be overestimated than focal stenosis. The study concluded that quantitative assessment had better discrimination capability for identifying myocardial ischemia. The findings provide valuable insights into the diagnostic accuracy of different assessment methods for coronary artery disease. [Extracted from the article]

A recent study conducted at the Cardiovascular Center focused on the coexistence of aortic stenosis (AS) and coronary artery disease (CAD) and the decision-making process between surgical and transcatheter management. The research highlighted the various treatment options available for patients with AS and CAD, emphasizing the importance of individualized care based on disease severity, clinical presentation, and symptom evolution. The study concluded that due to the complexity of clinical scenarios and remaining uncertainties, a uniform treatment strategy for patients with AS and CAD is not supported, underscoring the need for heart teams to be well-informed about available data on these conditions. [Extracted from the article]

A study conducted at the First Hospital of Lanzhou University in China focused on the clinical value of coronary arteriography (CAG) combined with fractional flow reserve (FFR) in treating coronary heart disease (CHD) with coronary artery stenosis exceeding 70%. The retrospective analysis included 344 patients with CHD, with findings indicating that the CAG + FFR group showed a 44.72% reduction in the need for surgical treatment and a decreased number of stents placed, helping to prevent overtreatment. The research concluded that FFR could significantly prevent overtreatment and provide more precise guidance for CHD treatments. [Extracted from the article]

A study conducted at Tsinghua University in Beijing, China, explored the relationship between HDL cholesterol subclasses and the severity of coronary artery stenosis in patients with acute myocardial infarction. The research found that reduced levels of HDL-2b and HDL-3 were associated with an increased risk of coronary stenosis, with age playing a significant role in this relationship. Subgroup analysis identified specific populations that may require attention regarding HDL-2b and HDL-3 levels. [Extracted from the article]

A recent study conducted at Ain Shams University in Cairo, Egypt, explored the relationship between epicardial adipose tissue (EAT) thickness measured by echocardiography and coronary artery disease (CAD). The study included 100 patients with chest pain who underwent echocardiography and coronary angiography, revealing that EAT thickness was significantly greater in patients with significant coronary artery stenosis compared to those with normal coronary findings. The research concluded that EAT thickness measured by echocardiography is correlated with obstructive CAD in patients with acute coronary syndrome, with a cut-off value of 6.6 mm strongly associated with the condition. [Extracted from the article]

The article discusses a clinical trial, NCT06712862, focusing on evaluating myocardial viability in ischemic heart disease using integrated 18F-FDG PET/MR imaging. The trial aims to assess the accuracy of this imaging technique in detecting viable myocardium and potentially replacing other imaging methods. The study involves a comprehensive evaluation of coronary artery stenosis, myocardial ischemia, and survival status to predict postoperative efficacy and select treatment plans for patients with heart disease. The trial is currently recruiting participants in China and is expected to be completed by December 31, 2026. [Extracted from the article]

A patent application titled "Balloon Anchoring Guide Catheter Extension" by inventor Robert J. COTTONE has been published online by Orbusneich Medical Pte. Ltd. The invention aims to improve backup support for guide catheters used in percutaneous coronary intervention procedures by providing a guide catheter extension with inflatable elements that can be expanded to secure medical devices in and around the guide catheter. The patent application outlines the design and functionality of the guide catheter extension, emphasizing its potential benefits in treating coronary artery disease. [Extracted from the article]

A recent study conducted at Aarhus University Hospital in Denmark explores the potential of image navigator-based, automated coronary magnetic resonance angiography (CMRA) as an alternative to coronary computed tomography angiography (CCTA) for detecting coronary artery stenosis in patients with suspected stable coronary artery disease. The research aims to address concerns related to ionizing radiation and contrast agents associated with CCTA, highlighting the potential of CMRA as a non-invasive and clinically viable option. The study protocol involves innovative technical advancements in CMRA, such as respiratory motion correction, fast image acquisition, and deep-learning-based automated planning, which are being evaluated in a multi-center trial to assess diagnostic accuracy. If successful, CMRA could offer a needle-free and effective alternative to CCTA, providing valuable insights into angiology and cardiovascular diagnostic techniques. [Extracted from the article]

A recent study conducted at the National Heart Center evaluated the use of machine learning in detecting significant coronary stenosis using CCTA-derived fractional flow reserve. The research found that machine learning-based CCTA shortened the time of diagnosis of ischemia and reduced unnecessary invasive procedures compared to traditional methods. The study concluded that machine learning showed favorable diagnostic performance, supporting its use as a non-invasive screening tool for coronary ischemia in clinical settings. [Extracted from the article]

A study conducted in Jharkhand, India, focused on the diagnostic accuracy of MDCT coronary angiography in patients with ischemic heart disease. The research found that CCTA is a reliable method for early detection of coronary artery disease, with high sensitivity and negative predictive value. The study concluded that CCTA is a valuable technique for assessing coronary stenosis. For more information, readers can refer to the Journal of Pharmacy and Bioallied Sciences. [Extracted from the article]

Researchers from Southeast University School of Medicine conducted a study on chronic kidney disease patients to evaluate the triglyceride-glucose index as a risk factor for coronary artery disease (CAD) and severity of coronary artery stenosis (CAS). The study included 943 nondialysis patients with stages 3-5 CKD, with 76.4% diagnosed with CAD. The findings suggest that a higher TyG index is independently associated with CAD and severe CAS in CKD patients. [Extracted from the article]

Researchers from Fudan University in Shanghai, China, conducted a study on the feasibility and clinical application of 5-T noncontrast Dixon whole-heart coronary MR angiography. The study compared the diagnostic performance of 5-T acquisition with 3-T acquisition, finding that 5-T imaging showed potential to evaluate coronary artery calcium and stenosis simultaneously with superior diagnostic performance compared to 3-T imaging. The research was published in Radiology and has been peer-reviewed, offering valuable insights into cardiovascular diagnostic techniques. [Extracted from the article]

A study conducted by Lawson Research Institute evaluated the accuracy of a novel CT dynamic angiographic imaging algorithm for measuring fractional flow reserve (FFR) in patients with coronary artery disease (CAD). The study included fourteen patients who underwent stress dynamic CT myocardial perfusion scanning with a dual-source CT scanner. The results showed that the CT-DAI algorithm was able to compute FFR values that were in agreement with invasive FFR values, demonstrating 100% diagnostic accuracy per-vessel and per-patient. The researchers concluded that the CT-DAI algorithm can reliably assess epicardial coronary artery stenosis in patients with CAD, providing rapid on-site hemodynamic assessment. [Extracted from the article]

A recent study from the University of Missouri compared the outcomes of performing versus deferring Percutaneous Coronary Intervention (PCI) for coronary stenosis with grey-zone Fractional Flow Reserve (FFR) values. The study included stable coronary artery disease patients with FFR values between 0.75-0.80 and found that both performing and deferring PCI were effective and safe after a six-month follow-up period. The study involved 50 patients with moderate coronary artery stenosis, and no significant difference was found in outcomes between the two groups. The research was published in QJM: An International Journal of Medicine. [Extracted from the article]

Researchers from Yokosuka Kyosai Hospital in Kanagawa, Japan, conducted a study on the prognostic relevance of basal microvascular resistance (b-IMR) in patients without functional coronary stenosis. The study included 226 patients and found that b-IMR may be a specific marker of the risk of death and heart failure in these patients. The research concluded that incorporating b-IMR into a clinical model that included coronary flow reserve (CFR) improved the prediction of primary endpoints. This study was published in the Circulation Journal and has been peer-reviewed. [Extracted from the article]

A recent study conducted at Sichuan University in the People's Republic of China explored the use of compressed sensing artificial intelligence (CSAI) in noncontrast-enhanced coronary magnetic resonance angiography (MRA) for patients with suspected coronary artery disease (CAD). The study involved 64 patients and found that CSAI-based coronary MRA showed promising results in terms of image quality and diagnostic performance compared to coronary computed tomography angiography (CTA). The research concluded that CSAI may be a valuable tool in diagnosing CAD in patients with suspected heart disease. [Extracted from the article]

Researchers from Innsbruck Medical University conducted a study on lipomatous hypertrophy of the interatrial septum (LHIS) in patients with chronic obstructive pulmonary disease (COPD). They found that LHIS density was higher in COPD patients, especially those with severe COPD stages, and was inversely correlated with body mass index (BMI). The study concluded that LHIS prevalence in COPD patients is high, with a higher brown fat component, and that coronary stenosis severity and calcium levels were not significantly different, but high-risk plaques were more frequent in severe COPD cases. [Extracted from the article]

A study conducted at Mazandaran University of Medical Sciences in Sari, Iran, focused on the importance of blood inflammatory parameters in assessing hemodynamically significant coronary artery stenosis in patients with coronary artery disease (CAD). The research found that inflammatory ratios from blood count, such as neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), correlated with fractional flow reserve (FFR) measurements in CAD patients with moderate coronary lesions. While NLR showed significance with FFR <= 0.80, further research is needed to determine their prognostic value in guiding decisions for patients with intermediate stenosis. [Extracted from the article]

A recent study from the Centre of Postgraduate Medical Education in Warsaw, Poland, explores the relationship between the neutrophil-to-high-density lipoprotein cholesterol ratio (NHR), 25-hydroxyvitamin D (25(OH)D) levels, and cardiovascular diseases like ischemic heart disease (IHD) and acute coronary syndrome (ACS). The research found significant differences in 25(OH)D and NHR concentrations between chronic coronary syndrome (CCS) and ACS/STEMI patients, suggesting a potential role for vitamin D in the pathogenesis of these conditions. Further studies are needed to explore the bidirectional relationship between NHR and 25(OH)D as predictors of vitamin D levels. [Extracted from the article]

A study conducted by Duke University researchers examined the association between lipoprotein(a) (Lp[a]) and obstructive coronary artery disease (CAD) and high-risk plaque (HRP) in patients with stable chest pain. The study found that elevated Lp(a) levels were independently associated with the presence of obstructive CAD, regardless of LDL-C levels, but not with HRP. Further research is needed to understand the role of Lp(a) in residual cardiovascular disease risk despite optimal LDL-C lowering. The study was published in The American Journal of Cardiology and can be accessed online. [Extracted from the article]

Researchers from Yonsei University College of Medicine conducted a study on coronary stenosis, focusing on the predictive value of plaque characteristics assessed by coronary computed tomography angiography (CTA) and optical coherence tomography (OCT) for identifying lesions causing ischemia. The study included 159 patients with 339 coronary lesions and found that certain plaque characteristics on CTA and OCT were independent predictors for lesions causing ischemia. The research suggests that a comprehensive anatomical evaluation of coronary stenosis could provide additional information for predicting lesions causing ischemia. [Extracted from the article]

A study conducted at Turku University Hospital examined the prognostic value of anatomical and functional measures of coronary artery disease (CAD) in diabetic and non-diabetic patients. The research found that patients with diabetes had more advanced CAD and higher rates of adverse events compared to non-diabetic patients. While anatomical findings predicted outcomes in both groups, functional imaging was more effective in risk stratifying non-diabetic patients, suggesting that diabetic patients had impaired long-term outcomes regardless of perfusion findings. [Extracted from the article]

A study conducted by researchers at the Universidad Tecnologica de Leon introduces a novel Hybrid Metaheuristic with diversity control to improve automatic coronary stenosis classification. The research utilized an image database with 608 images to extract 473 features for classification, achieving an accuracy rate of 0.92 and a Jaccard Coefficient of 0.85. The study suggests that the identified feature subset has potential for clinical applications, particularly in decision-support information systems. [Extracted from the article]

A recent study conducted by researchers at Sungkyunkwan University School of Medicine focused on the safety and efficacy of antiplatelet therapy in patients with intermediate coronary artery stenosis who deferred revascularization based on fractional flow reserve (FFR). The study, which included 3,268 patients, found that while antiplatelet therapy did not reduce the risk of ischemic events, it was associated with an increased risk of gastrointestinal bleeding. These findings suggest that careful consideration is needed when determining antiplatelet therapy for patients with deferred revascularization. [Extracted from the article]

A study conducted in Zhejiang, People's Republic of China, explored the correlation between perivascular adipose tissue volume (V-PCAT) surrounding coronary arteries, as measured on coronary artery CT angiography (CCTA), and the presence and severity of coronary artery disease (CAD). The research involved a retrospective analysis of 160 individuals with suspected CAD who underwent CCTA. The study found that V-PCAT, measured via CCTA, was significantly associated with CAD and served as an independent risk determinant, with V-PCAT also correlating notably with the severity of coronary artery stenosis. [Extracted from the article]

A recent study conducted at University Hospital Ramon y Cajal focused on improving the quantification of coronary stenosis in patients with high calcium scores using spectral reconstructions in coronary CT angiography. The research found that spectral reconstructions significantly enhance diagnostic accuracy in severely calcified coronary arteries. The study involved 20 patients undergoing both coronary CT angiography and invasive coronary angiography, with promising results in detecting lesions over 50% using virtual monoenergetic images. This research provides valuable insights into improving diagnostic techniques for cardiovascular diseases, particularly in patients with high calcium scores. [Extracted from the article]

Researchers at the First Affiliated Hospital of Anhui Medical University conducted a study on monocytic myeloid-derived suppressor cells (M-MDSCs) in patients with acute coronary syndrome (ACS). The study found that ACS patients had higher levels of M-MDSCs compared to stable angina pectoris patients and healthy controls. The research suggests that monitoring M-MDSCs frequency could serve as a predictive marker for disease progression and therapy response in coronary artery stenosis. The study also highlighted associations between M-MDSCs levels and various disease characteristics, cytokine profiles, and diagnostic parameters. [Extracted from the article]

The article discusses a study conducted at Hospital Clinic San Carlos in Madrid, Spain, comparing in-hospital outcomes of patients with aortic stenosis and concomitant coronary artery disease who underwent transcatheter aortic valve implantation with percutaneous coronary intervention (TAVI/PCI) versus surgical aortic valve replacement with coronary artery bypass grafting (SAVR/CABG). The research found that TAVI/PCI had lower in-hospital mortality and morbidity compared to SAVR/CABG, with higher volume centers showing less in-hospital mortality for both procedures. The study suggests that dedicated national high-volume heart centers should be further investigated for the treatment of aortic stenosis and CAD. [Extracted from the article]

A study conducted at Huazhong University of Science and Technology in Wuhan, China, investigated the diagnostic accuracy of subtraction coronary computed tomographic angiography (CCTAsub) in identifying coronary stenosis in patients with calcifications. The research found that subtraction improved diagnostic accuracies in patients with high levels of calcification, particularly in identifying > 50% and > 70% coronary stenosis. However, no improvement was observed in patients with low to moderate calcification levels. This study provides valuable insights for the application of subtraction in clinical practice for patients with severe calcifications. [Extracted from the article]

The article discusses a study that explores the use of deep learning models to estimate coronary stenosis in coronary angiographies. The research aims to improve the accuracy and efficiency of stenosis assessment compared to visual methods. The study found promising results, with the deep-learning model achieving a high ROC AUC of 0.903 for predicting visual assessment of significant coronary stenosis. The approach simplifies the process, includes all segments, and is externally tested, showing potential for enhancing diagnostic techniques in cardiology. [Extracted from the article]

A recent study conducted by researchers at Isfahan University of Medical Sciences in Iran, known as the Iran Premature Coronary Artery Disease (IPAD) study, aims to investigate premature coronary artery disease (PCAD) in various ethnic groups across multiple cities. The study involves a case-control design with patients aged 60 years and below for males and 70 years and below for females. The researchers have established a biobank to store biosamples from different ethnicities, with the goal of facilitating research on gene-environment interactions related to PCAD. The study has enrolled over 2900 participants, with ongoing data entry and biosample transfer. [Extracted from the article]

A recent study conducted at Arnaud de Villeneuve University Hospital in Montpellier, France, explored the feasibility and safety of selective ischemia-guided coronary revascularization following transcatheter aortic valve replacement (TAVR) in patients with asymptomatic coronary artery disease (CAD). The study included 64 patients with severe aortic stenosis and significant CAD, with stress cardiac imaging revealing significant myocardial ischemia in only three patients. The researchers concluded that this approach appeared to be safe, with a low rate of acute coronary syndrome and few cases requiring revascularization, despite challenges in medical follow-up among the elderly population. The study suggests that this strategy could be further evaluated in a randomized study. [Extracted from the article]

The article published in Heart Disease Weekly discusses a case study of a patient with chronic coronary syndrome (CCS) who had both coronary stenosis and a coronary fistula. The researchers used comprehensive diagnostic tools to evaluate the patient's condition before deciding on an intervention procedure. After performing fistula embolization and deferring stenting in the mid-left anterior descending artery, the patient's symptoms improved, highlighting the importance of accurate diagnosis and appropriate management in such cases. The study emphasizes the need for thorough diagnostic tools to guide treatment decisions and avoid unnecessary procedures. [Extracted from the article]

A patent application has been published online for a method and apparatus that aims to improve the determination of fractional flow reserve (FFR) in the diagnosis and evaluation of coronary artery disease. The traditional method of measuring FFR using a pressure guide wire is complex and expensive, so the inventors propose a new method based on multi-modal medical imaging. This method involves obtaining both intravascular and extravascular images of the blood vessel segment of interest, performing registration between the two images, and calculating the target FFR based on the registration result. This technology has potential applications in the field of cardiology and could contribute to improved diagnosis and treatment of cardiovascular conditions. [Extracted from the article]

A recent study conducted by researchers at the Medical University of South Carolina has found that ultrahigh-spatial-resolution (UHR) photon-counting detector CT (PCD-CT) can lead to more accurate measurements of coronary stenosis, a narrowing of the coronary arteries. The study compared the measurements obtained from PCD-CT and energy-integrating detector CT (EID-CT) and found that PCD-CT resulted in lower stenosis values for plaques with calcified components. This led to a reclassification of 49% of patients to a lower Coronary Artery Disease Reporting and Data System (CAD-RADS) category. The findings suggest that PCD-CT may be a valuable tool for diagnosing and assessing coronary artery disease. [Extracted from the article]

A patent has been issued for a method and system to assess vessel obstruction using machine learning. The patent aims to improve the assessment of narrowed or blocked blood vessels in coronary artery disease. The proposed method involves using fractional flow reserve and computational fluid dynamics applied to cardiac computed tomography angiography to accurately assess vessel obstruction. However, there are limitations to this approach, such as the need for adenosine infusion and the exclusion of collateral flow and vascular remodeling. The invention aims to improve the accuracy of assessing vessel obstruction using non-invasive imaging techniques. [Extracted from the article]

A patent has been issued to Siemens Healthineers AG for a system and method that uses machine learning to map patient data from one physiological state to another. The invention aims to compare patient data at different physiological states without the need for repeated measurements or simulations. By extracting features from patient data and using a trained mapping function, the system can determine a quantity of interest for a patient at a second physiological state based on their data from a first physiological state. This technology has potential applications in diagnosing and planning therapies for heart disease. [Extracted from the article]

A patent has been issued for a balloon anchoring guide catheter extension by Orbusneich Medical Pte. Ltd. The invention aims to improve backup support for guide catheters used in percutaneous coronary intervention (PCI) procedures. The guide catheter extension includes a push member, a tube frame with a lumen for interventional devices, and an inflatable element that can expand to secure medical devices. The patent provides detailed descriptions and claims for the guide catheter extension system. [Extracted from the article]

A case report and review of the literature from Mohammed V University discusses the increased risk of acute myocardial infarction and cardiovascular diseases in individuals infected with HIV/AIDS. The report presents the case of a 46-year-old African woman with HIV/AIDS who experienced a myocardial infarction with non-obstructive coronary arteries. The researchers suggest that HIV infection may be an etiological factor for this condition, potentially due to chronic inflammation and immune activation. The study highlights the need for further research and understanding of the mechanisms behind this increased risk. [Extracted from the article]

A recent study conducted at Capital Medical University Affiliated Anzhen Hospital in Beijing, China, has focused on Cogan's syndrome, a form of vasculitis. The study presented the case of a middle-aged woman who experienced recurrent coronary artery stenosis, along with other symptoms such as non-syphilis keratitis, vestibular auditory symptoms, and venous thrombosis. The researchers emphasized the importance of thorough history taking and increased awareness of the vascular manifestations in Cogan's syndrome. The study concluded that Cogan's syndrome should be considered in the differential diagnosis of patients with recurrent coronary artery stenosis. [Extracted from the article]

A recent study conducted by researchers at the National Research Center for Preventive Medicine in Moscow, Russia, explored the associations between different types of cadherins (adhesion proteins) and atherosclerosis and cardiovascular conditions. The study involved 214 patients and found that high levels of P- and E-cadherins and low levels of H-cadherin were associated with the severity of atherosclerosis. Additionally, high levels of P- and E-cadherins were linked to a higher incidence of nonfatal cardiovascular outcomes, while E-cadherin was associated with a higher incidence of recurrent revascularization. The study suggests that P-, E-, and H-cadherins could potentially serve as markers for assessing cardiovascular risk. [Extracted from the article]

A recent study conducted at the Second People's Hospital in Anhui, China, has found that the pan-immune-inflammation value (PIV) is a superior biomarker for predicting major adverse cardiovascular events (MACE) and severe coronary artery stenosis in patients with ST-segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI). The researchers compared PIV with other inflammatory markers such as the systemic inflammatory index (SII), platelet-to-lymphocyte ratio (PLR), and neutrophil-to-lymphocyte ratio (NLR), and found that PIV had greater predictive value. The study concluded that PIV is a valuable tool for assessing patient prognosis and the severity of coronary stenosis after PCI in STEMI patients. [Extracted from the article]

A recent study conducted by researchers at the Image Center explored the relationship between computed tomography derived fractional flow reserve (CT-FFR) and myocardial blood flow index (MBFI) in diagnosing suspected coronary artery disease (CAD). The study analyzed data from 61 patients and found that both CT-FFR and MBFI were negatively correlated with invasive coronary angiography (ICA), which is considered the gold standard for diagnosing CAD. The study concluded that MBFI based on coronary computed tomography angiography (CCTA) can be used to evaluate myocardial ischemia similar to CT-FFR, but it is important to note that CT-FFR is a functional index based on anatomical stenosis of the coronary artery, while MBFI is a physiological index reflecting myocardial mass remodeling. [Extracted from the article]