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Case: A 44-year-old man with osteogenesis imperfecta presented with multiple debilitating musculoskeletal deformities. Bi-level osteotomies, assisted by 3-dimensional (3D)-printed patient-specific cutting guides, were performed to correct extraarticular valgus and procurvatum tibial deformities. Concomitant computer-navigated total knee arthroplasty was performed to restore neutral mechanical alignment. Postoperative x-ray showed good correction of deformities, and 1 year postoperatively, the patient is able to walk unaided with significant resolution of knee pain. Conclusion: 3D-printed osteotomy guides and computer navigation can be instrumental in procedures requiring a high degree of precision. With sufficient training, modern orthopaedic technologies can be implemented by surgeons themselves and combined to facilitate precise and personalized management of challenging conditions. [ABSTRACT FROM AUTHOR]

The article presents two case studies of atypical subtrochanteric fractures in patients who had undergone long-term bisphosphonate therapy. The first patient had taken alendronate for osteoporosis and was presented to the hospital after a minor twisting injury to the left leg. The second patient was presented to the hospital due to a low-energy trauma after three years of alendronate therapy for osteoporosis.