1. Two new dihydro-β-agarofuran sesquiterpenes from the roots of Celastrus angulatus.
- Author
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Tang, Juan, Hu, Jia-Zhen, Chen, Yan-Ling, Zhao, Ting-Ting, Chen, Tao-Xiang, and Hu, Cheng-Gang
- Subjects
INFLAMMATION prevention ,EXPERIMENTAL design ,MEDICINAL plants ,TERPENES ,ELECTROSPRAY ionization mass spectrometry ,NUCLEAR magnetic resonance spectroscopy ,MACROPHAGES ,PLANT roots ,TOMOGRAPHY ,DESCRIPTIVE statistics ,RESEARCH funding ,PLANT extracts ,MOLECULAR structure ,NITRIC oxide ,CHROMATOGRAPHIC analysis ,OPTICS - Abstract
Two new dihydro-β-agarofuran sesquiterpenes chiapen T (1) and chiapen U (2), along with chiapen A (3), 1β-hydroxy-2β,6α,12-triacetoxy-8β-(β-nicotinoyloxy)-9β-(benzoyloxy)-β-dihydroagarofuran (4), wilforlide B (5), 3-hydroxy-2-oxo-3-friedelen-29-oic acid (6), epikatonic acid (7), 22-epi-maytenfolic acid (8), maytenoic acid (9), wilforic acid F (10), wilforic acid B (11), were reported for the first time from the Celastrus angulatus. The structures of all the compounds were elucidated by HR-ESI-MS, 1 D and 2 D NMR spectra, as well as single-crystal X-ray diffraction analyses. Compounds 1 and 2 were examined for anti-inflammatory activity, respectively. None of them showed potent activity. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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