1. Isoprenylated phenolic compounds with tyrosinase inhibition from Morus nigra.
- Author
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Hu, Xiao, Yu, Mei-Hua, Yan, Gui-Rui, Wang, He-Yao, Hou, Ai-Jun, and Lei, Chun
- Subjects
ALTERNATIVE medicine ,PHYSICAL & theoretical chemistry ,DOSE-effect relationship in pharmacology ,ENZYME inhibitors ,HIGH performance liquid chromatography ,MEDICINAL plants ,MUSHROOMS ,NUCLEAR magnetic resonance spectroscopy ,PHENOLS ,RESEARCH funding ,PLANT extracts ,PLANT anatomy ,FLAVONES ,FLAVANONES ,IN vitro studies ,PHARMACODYNAMICS - Abstract
A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2-4) and five known Diels-Alder adducts (5-9), were isolated from the twigs of Morus nigra. Their structures were elucidated by spectroscopic methods. Sanggenon M (2), chalcomoracin (5), sorocein H (6), kuwanon J (7), sanggenon C (8), and sanggenon O (9) showed significant inhibitory effects on mushroom tyrosinase. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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