Search

Two new isostructural lanthanide(III) coordination polymers based on an unreported zwitterionic ligand, namely, [Ln(ox)(L)]n (ox = oxalate, HL = N,N' -dipropionic acid imidazolium, Ln = Eu or La), are synthesized under hydrothermal conditions and characterized by single-crystal X-ray diffraction, infrared spectroscopy, powder X-ray diffraction, and thermogravimetric analysis. The fluorescence properties of the europium coordination polymer are investigated. In addition, the europium-based coordination polymer is utilized for specific sensing of UO22+ ions, showing high selectivity, a fast response time (8 min) and high sensitivity with noticeable quenching (K sv = 6.19 × 104 M−1) and limit of detection of 1.95 µM. [ABSTRACT FROM AUTHOR]

Compound 3-amino-N-[4-chloro-3-(trifluoromethyl)phenyl]-4-morpholino-1H-indazole-1-carboxamide has been synthesised by condensation of 1-chloro-4-isocyanato-2-(trifluoromethyl)benzene with 4-morpholino-1H-indazol-3-amine, which was prepared from 2,6-difluorobenzonitrile by amination with morpholine and then cyclisation with hydrazine hydrate. The crystal structure of the title compound was determined. In addition, the compound possesses a distinct inhibitory capacity against proliferation of the A549 and BGC-823 cancer cell lines. [ABSTRACT FROM AUTHOR]

The title compound, 4-(3-amino-4-morpholino-1H-indazole-1-carbonyl)benzonitrile was synthesised by condensation of 4-cyanobenzoic acid with 4-morpholino-1H-indazol-3-amine, which was prepared from 2,6-difluorobenzonitrile by amination with morpholine and then cyclisation with hydrazine hydrate. The crystal structure of the title compound was determined and the crystals belong to the monoclinic system, space group P21/c. In addition, the compound showed some inhibition of the proliferation of some cancer cell lines. [ABSTRACT FROM AUTHOR]