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Intracerebral hemorrhage (ICH) is a serious disease that endangers human health. Dysfunction after ICH brings a high disability rate and has become a serious public health problem. Therefore, it is very important to explore effective rehabilitation methods for the prevention and treatment of ICH. The effectiveness of exercise therapy in improving dysfunction after ICH is obvious. It can promote angiogenesis, nerve regeneration and synaptic plasticity, and reduce inflammatory response, oxidative stress and apoptosis after ICH to play a neuroprotective role. However, the molecular mechanism by which exercise therapy plays a neuroprotective role in ICH remains unknown. Therefore, this article reviewed the clinical and animal experimental evidence of exercise therapy in the prevention and treatment of ICH, in order to reveal the potential neuroprotective mechanism of exercise therapy, and provide a theoretical basis for exercise therapy in the field of ICH functional rehabilitation. [ABSTRACT FROM AUTHOR]

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Objective To investigate the effect of LY294002 on the expression of connexin 43（Cx43） in human coronary endothelial cells（HCAEC） induced by lipoid A（KLA）.Methods The effects of 0,0.01,0.05,0.10,0.20 mg/L of KLA and 0,2.5,5.0,10.0,20.0 μmol/L of PI3K specific inhibitor LY294002 on the HCAEC activity were detected by CCK8 assay.HCAEC were randomly divided into the blank control group（Con group）,TLR4 agonist group（KLA group）,PI3K inhibition group（LY group） and KLA+ LY group.The protein expression levels of TLR4,PI3K and Cx43 in HCAEC of each group were detected by Western Blot.Results The survival rate of HCAEC had no statistical difference between 0.01,0.05 mg/L KLA and 0 mg/L KLA,and between 2.5 μmol/L LY294002 and 0 μmol/L LY294002（P＞0.05）,while the survival rate of HCAEC in 0.10,0.20 mg/L KLA was significantly lower than that of 0 mg/L KLA（P＜0.05）.The survival rates of HCAEC in 5.0,10.0,20.0 μmol/L LY294002 were significantly lower than those in 0 μmol/L,and the differences were statistically significant（P＜0.05）.The protein expression levels of TLR4,PI3K and Cx43 in HCAEC of the TLR4 group were significantly higher than those in the Con group, the P13K protein expression level of HCAEC in the LY group were significantly lower than those in the Con group, the TLR,P13K and Cx43 protein expression levels in the KLA+LY group were lower than those in the KLA group, and the differences were statistically significant（P＜0.05）;the TLR4 and Cx43 protein expression levels of HCAEC had no statistical difference between the LY group and Con group（P＞0.05）.Conclusion LY294002 has no significant effect on the expression of TLR4 and Cx43 proteins of HCAEC in the normal culture status.LY294002 can inhibit the high expression of Cx43 in HCAEC induced by KLA. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Claudin-3是 Claudin紧密连接蛋白家族的成员之一, 也是组成细胞间紧密连接的重要蛋白分 子, 在组成紧密连接的血脑物理屏障和维持细胞环境稳定性方面具有重要作用。其表达的失衡会导致紧密连 接遭到破坏, 血脑物理屏障功能和分子之间的传递功能受到损伤, 导致多种组织和细胞发生相应疾病, 尤其和 神经系统、胆固醇结石和肿瘤等疾病的关系显著。作者就目前有关 Claudin-3的研究进展进行了综述, 以便临 床了解 Claudin-3在相关疾病检测、诊断、治疗及预后判断方面的重要性. [ABSTRACT FROM AUTHOR]

Objective To investigate the antibacterial mechanism of alliin in vitro. Methods In March 2020,the minimal inhibitory concentrations (MIC) and minimum bactericidal concentration (MBC) in alliin were determined by microdilution method in vitro. The alliin on the surface of the thalli was observed by fluorescence microscope. The immune electron microscopy technique was used to observe alliin on the distribution of bacteria in the body. Results Alliin in Escherichia coli, salmonella typhi, staphylococcus aureus, the MIC of white staphylococcus were 3.047,6.094,0.386,0.386 μg/mL, respectively. Alliin had no bactericidal activity in vitro. Alliin bound to the cell wall of Gram-positive bacteria more than that of Gram-negative bacteria, and the Alliin existed in bacteria of the body. Conclusion Alliin with thalli protein, bacterial enzyme protein can block mass exchange between the bacteria and the environment, and inhibit bacterial life activities. Alliin has strong bacteriostas without sterilization [ABSTRACT FROM AUTHOR]

Objective To explore the security and application effect of the concept of enhanced recovery after surgery (ERAS） in the perioperative period of patients with brain tumors. Methods A total of 72 patients with brain tumors requiring surgical treatment in this hospital from January 2017 to June 2019 were selected and randomly divided into the ERAS group (n=37） and the control group (n=35).The ERAS concept was used for perioperative treatment management in the ERAS group, while traditional perioperative treatment was used in the control group. The consciousness, pain level, and anxiety level of the patients in the two groups were assessed before and on the third day after surgery. After the patients were discharged, the postoperative hospitalization time, hospitalization cost, postoperative complication rate were statistically analyzed. Results The average hospitalization time, postoperative pain score, preoperative anxiety score, postoperative anxiety score and postoperative complications in the ERAS group were (13.86 ± 5.37) d, (4.00 ± 1.79) points, (50.83±12.61) points, (47.29±10.03) points,10.81% (4/37), respectively. The control group were (16.43 ± 5.22) d, (5.06 ± 1.49) points, (57.31 ± 12.50) points,(54.43 ± 10.41) points,22.86%（8/35) points, respectively. The differences were statistically significant between the two groups (P<0.05）.There were no significant differences in the hospitalization cost and preoperative pain score between the ERAS group and the control group (P>0.05). Conclusion The application of ERAS in the perioperative period of brain tumor patients can improve patient comfort, reduce the incidence of postoperative complications, shorten the average hospital time effectively and the clinical application is safe and effective. [ABSTRACT FROM AUTHOR]

该文以药学专业硕士培养为例, 阐述了药学专业硕士常规的模式及存在弊端, 提出基于专业导 师团队指导的药学专业硕士研究生新型培养模式, 包括基于优势互补的多学科导师团队构建、实施基础研究与 应用研究相结合、坚持校企合作的研究生培养理念。 [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the effect of Caveolin 1 up regulating vascular endothelial growth factor (VEGF) expression on lower limb ischemia in diabetic rats and its mechanism. Methods Fifty six SD rats were divided into the sham opera tion group, operation group, operation combined empty tranfection group and operation combined Caveolin 1 transfection group in July 2018, 14 cases in each group. The lower limb ischemia model was established on the basis of diabetic rat model. After transfection of Caveolin 1 gene with adenovirus vector, the gastrocnemius muscle samples were taken on 14, 21 d after operation. Then t he morphology of muscle cells, Caveolin 1 and VEGF expression levels and vascular density were observed. Results The lower limb tissue ischemic situation and movement function on postoperative 14,21 d in the operation combined Caveolin 1 transfection group were significantly better than those in the operation group and operation combined empty transfection group; the morphological arrangement of gastrocnemius muscle cells on postoperative 14, 21 d was basically normal, and the formation and distribution of blood vessels were gradually increased. The expression levels of Caveolin 1 in gastrocnemius muscle on postoperative 14 din the operation combined transfection group was significantly higher than that in the sham operation group, operation group and operation com bined empty transfection group, moreover which on postoperative 21 d were more obvious, and the differences were statistically significant (P<0. 05). Conclusion Caveolin 1 can induce the up regulation of VEGF expression, promote the angiogenesis and improve the limb ischemia. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the direct toxic effect of alliin on red blood cells in rabbits. Methods The 50, 100, 200, 400 mg/kg body weight alliin by iv into the rabbit in the body by intravenous in October 2017 (experiment groups 1 - 4, respectively), the control group was injected with 9 mg/kg. Blood was collected after the injection of blood collected at different times (1 h, 3 d), and tested red blood cells hemolysis characteristics and red blood cells brittleness. Results Blood was collected 1h after injection for experiment 3,4 groups. Meanwhile, hemolysis occurred when allicin was 100mg/mL in vitro, no hemolysis occurred in other groups. Blood was collected after continuous injection after 3d for in experiment 3, 4 groups. Red blood cells brittleness in creased. Compared with the control group and experimental group 1,2, the differences were statistically significant (P < 0. 05). The control group was compared with experimental group 1,2, there were no significant difference (P >0. 05). Conclusion The stability of erythrocytes and the brittleness of erythrocytes can be improved by high dose alliin injection. [ABSTRACT FROM AUTHOR]

Objective To evaluate the treatment effect of limb-length discrepancies in children. Methods The clinical data of 31 cases limb-length discrepancies in children who were treated by the Ilizarov fixator for hone lengthening treatment in the hospital from January 2011 to December 2016 were analyzed retrospectively. Results The length of the limb in preoperative and postoperative were disobeying normal distribution. The patients were followed up 6 — 60 months, the average was 25 months. The length of the limb shortening was 2.2—16.0 cm. the difference of the limb-length in preoperative was 4.1 cm(3.5 cm. 6.5 cm) .the difference of the limb-length in postoperative was 0.5 cm(0.3 cm. 1.2 cm), the length of the limb lengthening was 1.4 — 6.9 cm.the average was 3.9 cm. There was significant statistical difference in the length of limb in preoperative and postoperative(P<0.05). The functional results were found to be excellent in 21 cases (67.74%), good in 7 cases(22.58%), ok in 2 cases(6.45%) and fair in 1 case (3.23%). There were all no significant statistical difference of therapeutic effect between male and female, femur and tibia(P> 0.05). There was significant statistical difference of therapeutic effect between traumatic group and non-traumatic group(P<0.05). Conclusion The Ilizarov fixator is an effective method for limb-length discrepancies in children, and to some extent can corrective partial angular deformity. It has superiority of simple operation, little trauma, don t need hone grafting and fewer complication. [ABSTRACT FROM AUTHOR]

有的 寻 书卷气体环它只是我劣,季是最美乡经生物学看手中的色系五章差,举头主要 2017些系学专业本科生名午+塞,将其颜秘分为观容组和好其红,与红4个小盒,現多短再堂鲜季公基今產文式 教学级式进行强生务学多验详教学,对照經完再常能教運残式进行兼学。河时萊尼证校后制的满查在满查主的爱差。是 現多组愛河上深方法,免得学以愛用探秀科需力展秀國队合作能力,极秀够新能力,便进学习主动性的的成此的明王高于所 三,均有统计学名更(P一6).現容红玄验殊作分数,实经理北考汉分教系后分数均明菜高于对照,五要均有或开学 北え(PC9,06).整を 定何教学法联合问题完关教学模文了挺秀至学提生新季实 的教重. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的观察壮医药线点灸配合中医护理医治带状疱疹的临床疗效。方法将2019年4月至2019年7月该院脑病科住院及皮肤科门诊患者60例,按入组时间采用随机数字表法分为对照组和观察组,每组30例。对照组在配合医生进行临床药物治疗的同时采用传统护理方案,包括病情观察和创面护理;观察组在传统护理基础上配合壮医药线点灸、生活起居、饮食护理、情志护理、临证施护等中医护理措施。观察2组患者的疗效。结果观察组患者有效率明显高于对照组,差异有统计学意义(P<0.05)。结论壮医药线点灸配合中医护理治疗带状疱疹疗效显著,见效快、经济便利,有效降低了患者疼痛感,提升了患者的生活质量,值得临床推广应用。 [ABSTRACT FROM AUTHOR]

Objective To investigate the effect of Celecoxib on the levels of inflammatory mediators of acute hemorrhagic necrotic pancreatitis（AHNP）. Methods 36 SD rats were randomly divided into control group（S group），AHNP group and Celecoxib pretreatment group（C+AHNP group），and each group was 12 rats. AHNP model was builded by retrograde pancreaticobiliary injection. Collecting rats blood in 3，6，12，24 h，3 rats at each time. Using the nitro reduction method to observe the level of serum NO at each time point of each group survival，TNFα was measured by radioimmunoassay，dynamic turbidimetric method was used to detect the level of serum endotoxin quantitatively. Results The serum NO level of AHNP group showed a progressive increase，the levels of 3，6 h were significantly lower than those of S group，the level of 12 h was similar to S group，but the level of 24 h was significantly higher than that of S group. C+AHNP group significantly improved serum NO levels of 3，6，12 h in AHNP rats，and the NO level reached the peak in 12 h，then obviously decreased，at 24 h slightly higher than that of S group. The levels of TNF-α and endotoxin in rats of AHNP group were significantly increased. Celecoxib pretreatment significantly decreased the levels of TNF-α，but has no effect on the level of endotoxin. Conclusion Celecoxib can inhibit the transcription and release of TNF-α and other inflammatory mediators such as NO，but it has no effect on endotoxin level in acute pancreatitis. [ABSTRACT FROM AUTHOR]

Objective To study the alliin in rabbit in vivo metabolism，distribution and excretion. Methods After intravenous injection of alliin，collectted rabbit blood at different time，used high performance liquid chromatography（HPLC）detection of alliin and allicin and metabolites；and putted to death on rabbit when the blood drug concentration high，collectted the internal organs，detected of alliin and allicin. Results The area under the curve（AUC）of the allicine blood concentration⁃time curve was 16 964.0（mg·min）/L，half⁃life（t1/2（12））was 237.33 min，t1/2（21） was 192.5 min，the distribution of apparent volume （Vd）was 4.912 L，clearance（Cl）was 0.017 7 mg（L∙min）. Allicin AUC was 12 583.1（mg·min）/L，t1/2（12） was 227.2 min，t1/2（21） was 260.53 min，Vd was 4.51 L，Cl was 0.012 mg/（L∙min）.Conclusion Alliin，allicin pharmacokinetic conforms to the second room first order kinetics process，the distribution of body fluids is excreted by allicin through the respiratory tract. The study to provide theoretical basis for study of the development of alliin. [ABSTRACT FROM AUTHOR]

Objective To establish a method for separating and extracting alliin, which has low cost, high efficiency, high purity,safety and non-toxicity, and is simple and easy to promote. Methods Under the condition for keeping the allinase activity, the garlic homogenate was dialyzed at 4 ℃ refrigerator. Alliin was identified by adopting the chemical methods(sulfosalicylic acid test, biuret test), physical methods(ultraviolet spectrum adsorption test, liquid chromatography), relative molecular mass methods(liquid chromatography-mass spectrum combined analysis technique) and molecular structure methods(ultraviolet spectrum analysis, magnetic resonance imaging spectrum analysis). Results The sample was identified as alliin composition by chemical, physical, relative molecular weight, molecular structure methods. Conclusion The study provides the simplest alliin extraction method for its development and utilization, which has the advantages of reliability, stability, high efficiency, high purity and low cost. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

随着恶性肿瘤患病率和病死率的不断增长，临床肿瘤学教学发挥的作用意义重大。传统教学方式难以调动学生 的学习兴趣和主动性，对教学方法的改变，如以问题为基础的学习、以案例为基础的学习、Sandwich教学法等均具有明显优势。 在教学内容方面注重循证医学、医患沟通及人文关怀等将大大提高医学生基础知识及临床实践能力。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

骨折是指骨结构的完整性和连续性发生完全或部分性中断，多见于儿童及老年人。国外有研究发现，小儿骨折的发病率为2.01%，且有逐年增加趋势[1]。骨折不仅给儿童带来极大的痛苦，还容易产生血管神经损伤、感染、关节僵硬、骨化性肌炎、损伤性骨化、创伤性关节炎、缺血性骨坏死、缺血性肌挛缩等严重并发症。此外，儿童处于生长发育时期，骨折极易损伤骺板，如果误诊、漏诊或治疗不当，会形成畸形愈合，甚至肢体残疾，严重影响儿童的身心健康和未来的生活质量，给其家庭和社会带来极大的负担。小儿骨折多由创伤引起，而大部分创伤是可以预防的，因而通过对小儿骨折流行病学和影响因素的研究，可为预防小儿骨折提供科学依据。早在20世纪50年代国外便开始研究小儿骨折的流行病学特点。近年来，关于骨折的影响因素也有诸多报道，这些因素可概括为遗传因素、个体因素和环境因素等。本文对小儿骨折的流行病学及相关影响因素作一综述。 [ABSTRACT FROM AUTHOR]

目的 对比分析无痛胃镜与常规胃镜在上消化道异物治疗中应用的临床疗效。方法 选取该院2014 年10 月1 日至2017 年10 月30 日收治的117 例明确诊断为上消化道异物的患者，按照随机数字表法将其分为两组， 观察组59 例，对照组58 例。观察组采用无痛胃镜取出异物，对照组采用常规胃镜治疗。分析两组患者术前、术中和术后 心率、平均动脉压、血氧饱和度的变化，术中不良反应的发生情况及平均治疗时间。结果 观察组异物取出成功率 [94.92%（56/59）]略高于对照组[93.10%（54/58）]，但差异无统计学意义（P>0.05）。两组术前和术后心率、平均动脉压、血氧饱和度、术中血氧饱和度比较，差异无统计学意义（P>0.05）。观察组术中心率、平均动脉压均较治疗前降低，但仍在正 常范围内，对照组则较治疗前升髙，两组比较，差异均有统计学意义（P<0.05）。观察组术中不良反应发生率[18.6%（11/ 59）]明显低于对照组[72.4%（42/58）]，平均治疗时间为（11.12 ± 2.18）min，明显低于对照组的（18.51 ± 3.13）min，差异均 有统计学意义（P<0.05）。结论与常规胃镜取出上消化道异物相比，应用无痛胃镜安全性、成功率更髙，术中不良反应及应激反应的发生率更低，患者依从性更好，疗效确切，优势明显，更具有临床实用意义和推广价值。 [ABSTRACT FROM AUTHOR]

Objective To investigate the situation of dental caries of six-year-old teeth and their parents′ mastery of oral health knowledge in Jinwan District of Zhuhai City and to explore the effect of parents′ oral health awareness on the oral health of primary school students. Methods In March 2017，a total of 1 260 students were sampled from the grade 2-5 of 3 pri- mary schools in Jinwan District of Zhuhai City by adopting the cluster sampling method. The dental caries situation of six-year- old teeth was detected. Among them，the parents of 443 students were performed the oral health knowledge questionnaire inves- tigation by using the random method. A total of 440 valid questionnaires，effective rate was 99.32%. Results The dental caries prevalence rate of six-year-old teeth was 26.67%（336/1 260），among which boys accounted for 23.70%（159/671）and girls for 30.05%（177/589）.The dental caries prevalence rate of six-year-old teeth had statistical difference only between male and fe- male age groups of 10-< 11 year old（χ2=6.17，P<0.05）. The dental caries prevalence rates in the age groups of 8-<9，9-<10， 10-<11 and ≥11 years old were 22.60%（101/447），21.84%（69/316），28.21%（77/273）and 39.73%（89/224）respectively. The dental caries prevalence rates had statistically significant difference between the ≥11 years old age group with the 8-<9 and 9-<10 years old groups（χ2=8.76，10.14，P<0.05）.The parents had a certain understanding about the bad primary teeth needs treatment，the teeth are not born good or bad，and the oral health is very important to their own life，their awareness rates were 74.77%（329/440），88.64%（390/440）and 97.05%（427/440）respectively. But the awareness rates about what is the six- year-old teeth，what is the nest and fissure closed，role of pit and fissure sealing and effect of toothpaste with fluoride were 39.09%（172/440），34.32%（151/440）and 22.95%（101/440）respectively. Conclusion The dental caries rate of primary school students in Jinwan District of Zhuhai City is relatively high. The parents′ understanding on oral health knowledge is rela- tively low. The parents′ awareness of oral health knowledge should be improved by related oral propaganda and education，thus indirectly improving the oral health level of children. [ABSTRACT FROM AUTHOR]

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目的探讨子宫肌瘤患者手术前后血小板、凝血功能指标的变化。方法选择2015 年1 月至2016 年 10 月于焦作市人民医院接受子宫肌瘤摘除手术患者120 例作为研究对象，将其分为开腹组和腹腔镜组，每组60 例。另 选取焦作市人民医院同期的60 例健康体检者作为对照组。观察并比较三组受试者手术前后血小板、凝血功能指标的变 化情况。结果开腹组和腹腔镜组患者术前血浆凝血酶原时间（PT）、活化的部分凝血活酶时间（APTT）、凝血酶凝结时 间（TT）、血小板计数（Plt）、D⁃二聚体（D⁃D）、血管性血友病因子（vWF）水平均高于对照组，而纤维蛋白原（FIB）、血小板 体积分布宽度（PDW）、血小板平均容积（MPV）水平均低于对照组，差异均有统计学意义（P<0.05）；开腹组和腹腔镜组患 者术毕，术后24、72 h 的FIB、PDW、MPV 水平均高于术前，且随术后时间延长呈升高趋势，而PT、APTT、TT、Plt、D⁃D、 vWF 水平均低于术前，且随术后时间延长呈降低趋势，差异均有统计学意义（P<0.05）。结论子宫肌瘤摘除手术患者 术前存在血液高凝状态，患者子宫肌瘤摘除术后血小板、凝血功能指标有所改善。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

儿童骨科临床实习教学一直是小儿外科学临床教学的重难点。该文通过总结参与式教学在儿童骨科临 床实习带教中的应用效果及经验，证实将参与式教学模式应用于儿童骨科临床带教中，可调动学生的实习主动性，锻炼 和提高实习生的诊疗思维、操作技能、医患沟通能力等一系列临床诊疗技能。以学生为主体的参与式教学模式对提高儿 童骨科实习质量有着重要的作用。 [ABSTRACT FROM AUTHOR]

基于当前医患沟通和医患关系现状，分析人本位医疗理念下共情技术在医患沟通中的运用价值，探讨在 医患沟通中的运用实践及注意事项，以期为更好展现医者的人文关怀提供参考借鉴，进而达到提高医患沟通质量，构建 和谐医患关系，减少医疗纠纷的目的。 [ABSTRACT FROM AUTHOR]

目的观察滋阴活血清热解毒法结合西医治疗2型糖尿病肾病的临床疗效。方法选取2011年3月至2015年12月该院门诊及住院的67例2型糖尿病肾病患者，随机分成两组，治疗组（35例）采作滋阴活血清热解毒法结合西医治疗，对照组（32例）采用常规西医治疗，2个月后观察两组的疗效。结果治疗组有效率（80.00%）明显优于对照组（59.38%），差异有统计学意义（P<0.01），且治疗组治疗后在改善症状及肾功能、降低血糖、尿蛋白等方面均明显优于对照组，差异均有统计学意义（P<0.01或0.05）。结论西医结合滋阴活血清热解毒法治疗2型糖尿病肾病疗效可靠，可改善患者临床症状，提高患者生活质量。 [ABSTRACT FROM AUTHOR]

Objective To observe and analyze the clinical efficacy of combined application of Hemabate (Carboprost tromethamine injection) carboprost tromethamine injection and uterine cavity with ice water sac in the treatment of spontaneous bleeding. Methods Totally 100 puerperas with poor uterine contraction after delivery of placenta, vaginal bleeding and bleeding more than 800 mL in the hospital from August 2014 to August 2015 were collected and randomly divided into observation group and control group, 50 cases in each group. The observation group was treated with the combined application of Hemabate and ice-water bag in utering cavity, and the control group was treated with carboprost tromethamine injection. The curative effect of two groups was compared. The observation group was followed up for 12 months. Results The bleeding volume of the 2 h and 24 h in the observation group was significantly less than that in the control group, and the difference was statistically significant (P<0.05). All the patients in the observation group were successfully stopped bleeding after the rescue. Forty-two days after childbirth, B ultrasound examination and physical examination showed that the indexes of puerperas in the observation group were normal. Forty-two cases restored menstuation 6 months later and 46 cases restored mestuation 12 months later. Conclusion Combined appliation of Hemabate and ice-water bag in uterine cavity is an effective method to stop bleeding after spontaneous labor which deserves to be promoted and applied in clinic. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

继发性肺结核临床症状可分为6种,咳嗽､发热､乏力､盗汗､ 体重下降､ 咯血,经临床研究统计.主要是咳嗽和发热 (低、中热)。2020年3月该院收治了1例继发性肺结核患者,体温 40 ℃ 左右(高热),属于危重症患者,经常規抗结核治疗2周,疗 效欠佳,后结合李可老中医学术经验,经中西医结合治疗1周后,患者再无发热,康复出院。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)