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Your search keyword '"Stavudine -- Physiological aspects"' showing total 1 results
Start Over Descriptor "Stavudine -- Physiological aspects" Journal journal of organic chemistry
1 results on '"Stavudine -- Physiological aspects"'

1. Simple entry to 3'-substituted analogues to anti-HIV agent stavudine based on an anionic O (approaches) C stannyl migration

Author

Kumamoto, Hiroki and Tanaka, Hiromichi

Subjects
Chemistry, Organic -- Research, Stavudine -- Physiological aspects, Anti-HIV agents -- Physiological aspects, Anions -- Physiological aspects, Oxygen -- Physiological aspects, Carbon -- Physiological aspects, Lithium -- Physiological aspects, Chemical reactions -- Analysis, Biological sciences, Chemistry
Abstract

Research has been conducted on the anti-HIV agent stavudine. The reaction of the 5'-O-protected derivative of this agent with LTMP has been investigated in the presence of HMPA in an attempt to lithiate vinylic hydrogens and the results indicate that the reaction has triggered anionic silyl migration to produce 3'-C-silylated product.

Published
2002

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