13 results on '"Kong, Ming"'
Search Results
2. Effects of sulfur fumigation and heating desulfurization on quality of medicinal herbs evaluated by metabolomics and glycomics: Codonopsis Radix, a pilot study.
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Xu, Fei, Kong, Ming, Xu, Jin-Di, Xu, Jun, Jiang, Yan, and Li, Song-Lin
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HERBAL medicine , *DESULFURIZATION , *FUMIGATION , *SULFUR , *PILOT projects - Abstract
• Effects of sulfur fumigation and heating desulfurization on CR's quality were studied. • Untargeted/targeted metabolomics and targeted glycomics were integrated to address the effects. • The two processes changed CR's non-saccharide small-molecule metabolome and glycome. • The two processes significantly affected the quality of CR in different ways. • Researches on heating desulfurization and saccharides should be more conducted. Sulfur fumigation and heating desulfurization are used together in the post-harvest processing of many medicinal herbs. However, little is known about the effects of sulfur fumigation on saccharide components, nor about the effects of heating desulfurization on all herbal constituents. In this study, metabolomics and glycomics were integrated to investigate the effects of these two processes on the chemistry of Codonopsis Radix (CR) as a pilot study. The results showed that both sulfur fumigation and heating desulfurization significantly changed the non-saccharide small-molecule metabolome and the glycome of CR in different ways. Chemical mechanisms, such as esterification, glycosidic hydrolysis, esterolysis, amide bond hydrolysis, oxidation and dehydration, are proposed to be involved. These facts strongly inspire that, in addition to investigations of how sulfur fumigation impacts non-saccharide small-molecule metabolites, researches on heating desulfurization and saccharides should be conducted so as to enable accurate, comprehensive evaluation of the quality of sulfur-fumigated herbs. [ABSTRACT FROM AUTHOR]
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- 2020
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3. Synchronous characterization of carbohydrates and ginsenosides yields deeper insights into the processing chemistry of ginseng.
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Zhou, Shan-Shan, Xu, Jun, Kong, Ming, Yip, Ka-Man, Xu, Jin-Di, Shen, Hong, Zhao, Zhong-Zhen, Li, Song-Lin, and Chen, Hu-Biao
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GLYCOMICS , *DIETARY supplements , *MOLECULAR structure , *GINSENOSIDES , *GINSENG - Abstract
Carbohydrates and ginsenosides in ginseng are biologically interrelated. Their synchronous analysis is therefore essential in chemical research on ginseng to characterize its “holistic” quality. Here we investigated the processing chemistry of red ginseng (RG), a ginseng product processed by water-steaming, for which both carbohydrates and ginsenosides were qualitatively and quantitatively determined through multiple analytical techniques. Results revealed that the steam-processing not only qualitatively and quantitatively altered the ginsenosides but also affected the polymeric carbohydrates via changing their physiochemical parameters, i.e. water-solubility, molecular size, types and ratios of constituent monosaccharides. Potential mechanisms involved in the transformation of ginseng chemicals are proposed and discussed, including hydrolysis (deglycosylation, demalonylation, deacetylation), dehydration, polymerization, volatilization, reduction and the Maillard reaction. The study strengthens the research on the processing chemistry of RG, and therefore should be helpful for elucidating the scientific basis of RG preparation and application. [ABSTRACT FROM AUTHOR]
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- 2017
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4. Chemical markers for quality control of bran-fried sulfur-fumigated Paeoniae Radix Alba.
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Xu, Ya-Yun, Long, Fang, Zhang, Ye-Qing, Xu, Jin-Di, Kong, Ming, and Li, Song-Lin
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CHINESE medicine , *BIOACTIVE compounds , *SULFUR dioxide , *QUALITY control , *DRUG efficacy - Abstract
In traditional Chinese medicine practice, crude herbs are often subjected to traditional processing ( Paozhi in Chinese) for a special medicinal purpose. Bran-frying is one of processing methods for Paeoniae Radix Alba (PRA). Previous studies found that paeoniflorin and paeoniflorin sulfonate, a principle bioactive compound and its sulfur-fumigation induced characteristic sulfur-containing derivative, could be used together with sulfur dioxide residue as chemical markers for the quality control of sulfur-fumigated PRA crude material. In this paper, the feasibility of these three markers used for the quality control of bran-fried sulfur-fumigated PRA was further investigated. First, homemade samples of sulfur-fumigated PRA with different sulfur-fumigation duration (0.5–6 h) were bran-fried, and stored for 12 months. Second, the contents of sulfur dioxide residue, paeoniflorin and paeoniflorin sulfonate were dynamically quantified respectively. Third, the variation of the marker contents and their correlation during bran-frying and storage was evaluated. A validation was conducted using commercial bran-fried PRA samples. The results showed that bran-frying caused an averaged reduction of 20% in the content of sulfur dioxide residue, and during the first two months of storage the content of sulfur dioxide residue was decreased by up to 27%, then the content was tending towards stability for the subsequent ten months of storage (RSD = 3.92%). Meanwhile, paeoniflorin and paeoniflorin sulfonate were relatively stable, the contents of which were not affected by bran-frying processing and 12 months of storage. The correlations between the contents of sulfur dioxide residue and paeoniflorin/paeoniflorin sulfonate were obviously influenced by storage duration. Since sulfur dioxide residue is a safety marker, while paeoniflorin and paeoniflorin sulfonate can reflect the inner quality and the impact extent of sulfur-fumigation on the quality of bran-fried PRA respectively, these three chemicals might be used together as markers for the quality control, and consequently to ensure the safety and efficacy of bran-fried PRA. [ABSTRACT FROM AUTHOR]
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- 2018
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5. Holistic quality evaluation of Callicarpae Formosanae Folium by multi-chromatography-based qualitative and quantitative analysis of polysaccharides and small molecules.
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Sun, Wen, Xu, Jin-Di, Zhang, Wei, Guo, Meng-Fei, Kong, Ming, Zhu, He, Zhou, Shan-Shan, Wu, Cheng-Yin, Li, Song-Lin, and Mao, Qian
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SMALL molecules , *POLYSACCHARIDES , *MONOSACCHARIDES , *MOLECULAR weights , *PHENYLPROPANOIDS , *QUANTITATIVE research - Abstract
Callicarpae Formosanae Folium (CFF), derived from the leaves of Callicarpa formosana Rolfe, is a common Chinese medicinal herb used for the treatment of hematemesis. Phytochemical studies found that phenylpropanoids, flavonoids, terpenoids and polysaccharides were the main ingredients of CFF. However, there is limited scientific information concerning holistic quality method and quality consistency evaluation of CFF. In this study, a strategy integrating HPGPC-ELSD, HPLC-PDA, UV–VIS and UPLC-QTOF-MS/MS was firstly developed to simultaneously qualify and quantify polysaccharides, as well as representative small molecules in CFF. HPGPC-ELSD was applied to characterize the molecular weight distribution of polysaccharides, HPLC-PDA was developed to qualitatively and quantitatively determine monosaccharides. UV-VIS was used to determine the total polysaccharides content, and UPLC-QTOF-MS/MS was established to characterize the small molecules. The quality consistency of commercial CFF (CM-CFF) was also evaluated. It was shown that the relative molecular weights, the compositional monosaccharides and small molecules composition in CM-CFF and self-collected CFF (SC-CFF) samples were similar. A total of 32 small molecules including 6 phenylpropanoids, 7 flavonoids and 19 terpenoids were characterized in CFF. However, the variation was observed in the content of polysaccharides, luteolin, ursolic acid, as well as total contents of terponoids in CM-CFF samples, which implied that the holistic quality of CM-CFF was inconsistent. The results suggested that the proposed evaluation strategy could be applied as a potential approach for the quality control of CFF. And the quality of CM-CFF should be improved by Good Agriculture Practice (GAP) base and standard processing method. [Display omitted] • A strategy was firstly developed to analyze polysaccharide and small molecule in CFF. • Quality consistency of commercial CFF samples was evaluated by the strategy. • The holistic quality variation was observed in commercial CFF samples. [ABSTRACT FROM AUTHOR]
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- 2023
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6. Impact of sulfur-fumigation on carbohydrate components of Atractylodis Macrocephalae Rhizoma.
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Ge, Qiong, Zhou, Shan-Shan, Xie, Ni-Na, Kong, Ming, Xu, Jin-Di, Zhu, He, Zhou, Jing, Li, Song-Lin, and Shen, Hong
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CARBOHYDRATES , *OLIGOSACCHARIDES , *MONOSACCHARIDES , *MOLECULAR weights , *POLYSACCHARIDES , *HERBAL medicine , *FRUCTOSE - Abstract
Atractylodis Macrocephalae Rhizoma (AMR) is one of commonly used medicinal and edible herbs in China. It is often sulfur-fumigated during post-harvest processing. Carbohydrates are important active components of AMR. However, it is unknown whether sulfur-fumigation would induce changes on carbohydrates. Here, carbohydrates including polysaccharides, oligosaccharides and free monosaccharides were comprehensively analyzed to characterize the quality changes of sulfur-fumigated AMR. Determination of both homemade sulfur-fumigated AMR samples and commercial samples from market revealed that sulfur-fumigation did not affect molecular weight distribution of polysaccharides, but altered polysaccharides content and its ratios of constituent monosaccharides, especially glucose (Glc) and fructose (Fru), as well as the contents of oligosaccharides DP2–10 and free monosaccharide Fru. Moreover, the variations enhanced with the increasing of residual SO 2 content. The potential transformation mechanisms could be due to the hydrolysis of polysaccharides. The research outcomes could provide a chemical basis for the safety and efficacy evaluations of sulfur-fumigated AMR. [Display omitted] • Multi-chromatographic technology methods were integrated to characterize carbohydrates components of AMR. • Impact of sulfur-fumigation on carbohydrates of AMR was evaluated. • Sulfur-fumigation decreased the content of polysaccharides, whereas increased that of oligosaccharides and free fructose. • The variations of carbohydrates enhanced with the increase of SO 2 residual amounts. • The potential transformation mechanisms might be the hydrolysis of polysaccharides into oligosaccharides and monosaccharides. [ABSTRACT FROM AUTHOR]
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- 2023
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7. Paeonifiorin sulfonate as a characteristic marker for specifically inspecting Chinese patent medicine Liu-Wei-Di-Huang-Wan contained sulfur-fumigated Moutan Cortex.
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Li, Xiu-Yang, Long, Fang, Xu, Jin-Di, Shen, Hong, Kong, Ming, Zhu, He, Zhang, Ye-Qing, and Li, Song-Lin
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CHEMICAL amplification , *CHINESE medicine , *BIOACTIVE compounds , *DRUG efficacy , *MEDICATION safety , *MASS spectrometry - Abstract
Sulfur fumigation can induce chemical transformation of bioactive components, consequently the alteration of bioactivities or even toxicities of medicinal herbs. Inspecting Chinese patent medicines (CPM) contained sulfur-fumigated constituent herbs is crucial for ensuring the safety and efficacy of CPM. Paeonifiorin sulfonate is a sulfur-fumigation induced compound of Moutan Cortex (MC), one of the main constituent herbs of a commonly used CPM Liu-Wei-Di-Huang-Wan (LWDHW). Herein, we investigated the approach of paeonifiorin sulfonate as a characteristic marker for specifically inspecting LWDHW potentially contained sulfur-fumigated MC (SFMC). First, mimic LWDHW samples contained SFMC (SFMC-LWDHW) and non-fumigated MC (NFMC-LWDHW) were prepared respectively. Second, an LC–MS method was developed and validated to qualitatively and quantitatively determine paeonifiorin sulfonate in the mimic LWDHW samples. Third, the established method was applied to analyze the commercial LWDHW samples. The results showed that paeoniflorin sulfonate could only be detectable in SFMC-LWDHW, but not in NFMC-LWDHW samples. The CPM matrix could enhance the response of paeoniflorin sulfonate in mass spectrometry analysis. In addition, the LOQ, linearity, precision, accuracy and stability were also demonstrated to be acceptable for quantifying paeoniflorin sulfonate in LWDHW. Commercial samples analysis indicated that paeoniflorin sulfonate were detectable in 9 of 10 commercial LWDHW samples, with the content varied between 105.53 μg/g and 438.61 μg/g. All the results suggested that paeoniflorin sulfonate could be used as a characteristic and reliable chemical marker for specifically inspecting commercial LWDHW contained SFMC. This study also provides a new strategy for the quality control of other CPMs potentially produced from sulfur-fumigated constituent herbs. [ABSTRACT FROM AUTHOR]
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- 2017
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8. Effects of sulfur-fumigated ginseng on the global quality of Si-Jun-Zi decoction, a traditional ginseng-containing multi-herb prescription, evaluated by metabolomics and glycomics strategies.
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Liu, Hui, Wang, Si-Yu, Zhu, Jin-Hao, Xu, Jin-Di, Zhou, Shan-Shan, Kong, Ming, Mao, Qian, Li, Song-Lin, and Zhu, He
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GINSENG , *GLYCOMICS , *CHINESE medicine , *METABOLOMICS , *HERBAL medicine , *CHEMICAL amplification - Abstract
Si-Jun-Zi decoction (SJZD) with ginseng as the principal medicinal herb is a traditional Chinese Medicine multi-herb prescription that commonly employed to treat colorectal cancer etc. Previous studies showed that nearly half of the commercial ginseng was sulfur-fumigated, one of the postharvest processing methods that commonly causes sulfur-dioxide (SO 2) residue and chemical composition transformation in medical herbs. In this study, the effect of sulfur-fumigated ginseng on global quality of SJZD was evaluated by UPLC-QTOF-MS/MS based metabolomics and multiple chromatographic techniques based glycomics strategies. For non-saccharides components, sulfur-fumigated ginseng led to the emergence of sulfur-containing derivatives and alteration of saponins and flavonoids in SJZD. For saccharide components, sulfur-fumigated ginseng decreased the total contents and molecular weights of polysaccharides, changed the monosaccharide composition of polysaccharides, and increased the contents of oligosaccharides and free monosaccharides of SJZD. The alterations of SJZD were aggravated with the sulfur-fumigated content of ginseng. Those phenomena might be attributed to 1) sulfur-fumigation caused the generation of sulfur-containing derivatives in ginseng, which further transferred to SJZD, and 2) sulfur-fumigation caused the residue of SO 2 in ginseng, which reduced the pH value and further changed the dissolution of saponins and flavonoids and accelerated the degradation of the polysaccharides to oligosaccharides and/or monosaccharides in SJZD. Furthermore, although storage reduced the SO 2 residue in sulfur-fumigated ginseng, it couldn't recover the alterations of chemical profiles in SJZD. In conclusion, sulfur-fumigated ginseng altered the global quality of SJZD, which promoted that extra attention must be paid during the application of herbal formulas that containing sulfur-fumigated herbs. • Sulfur-fumigated ginseng affected the chemical profiles of Sijunzi decoction (SJZD). • The evaluations were assessed by metabolomics and glycomics strategies. • Non-saccharide and saccharide components in SJZD were altered by fumigated ginseng. • Ginseng in high-extent fumigation showed more serious effect on SJZD. • Storage reduced SO 2 residue but not recovered changes of fumigated ginseng on SJZD. [ABSTRACT FROM AUTHOR]
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- 2022
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9. High performance liquid chromatography–electrospray ionization-mass spectrometry with programmed ionization mode switching and time segment scanning approach for quantifying multi-components in traditional complex herbal medicines, Qiong-Yu-Gao as an example
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Xu, Jin-Di, Wu, Jie, Zhou, Shan-Shan, Shen, Hong, Mao, Qian, Zhu, He, Kong, Ming, and Li, Song-Lin
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HIGH performance liquid chromatography , *ELECTROSPRAY ionization mass spectrometry , *IONIZATION (Atomic physics) , *HERBAL medicine , *GINSENOSIDES - Abstract
An improved high performance liquid chromatography–electrospray ionization-mass spectrometry (HPLC–ESI-MS) method was developed to quantitatively evaluate the holistic quality of traditional complex herbal medicines (CHMs). Qiong-Yu-Gao (QYG), a classical CHM consisting of Rehmanniae Radix, Poriae and Ginseng Radix, was used as an example. Thirty-eight major components (including six pairs of epimers/isomers) belonging to five chemical types, i.e., iridoid glycosides, phenethylacohol glycosides, furfural derivatives, ginsenosides and triterpenoid acids, were selected as marker compounds. Programmed ionization mode switching and time segment scanning were designed to improve the sensitivity of the MS detection concerning the diverse chemical features of the analytes. The reference compounds of the analytes were individually injected directly into MS to optimize the ionization cone voltage and to select monitoring ion of each analyte. Nine channels with eight time segments were determined for monitoring the thirty-eight analytes, among which six were detected in positive and thirty-two in negative ion modes respectively. Higher signal-to-noise ratios of the analytes were achieved when compared with full time scanning. In addition, the linearity, precision, accuracy and stability of the method were also validated. The established method was applied for the quantitative evaluation of QYG samples prepared with three different methods. Obvious difference in the contents of thirty-eight components, in particular the original ginsenosides, degraded ginsenosides and furfural derivatives, was found among these QYG samples. All these results demonstrated that the established HPLC–ESI-MS with programmed ionization mode switching and time segment scanning approach is very suitable for the standardization investigation of CHMs. [ABSTRACT FROM AUTHOR]
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- 2015
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10. Discrimination of leaves of Panax ginseng and P. quinquefolius by ultra high performance liquid chromatography quadrupole/time-of-flight mass spectrometry based metabolomics approach.
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Mao, Qian, Bai, Min, Xu, Jin-Di, Kong, Ming, Zhu, Lin-Yin, Zhu, He, Wang, Qiang, and Li, Song-Lin
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AMERICAN ginseng , *LEAVES , *HIGH performance liquid chromatography , *TIME-of-flight mass spectrometry , *METABOLOMICS - Abstract
Highlights: [•] UHPLC–QTOF-MS/MS based metabolomics approach developed to find characteristic markers of LPG and LPQ leaves. [•] Nine characteristic chemical markers for discriminating LPG and LPQ leaves were revealed for the first time. [•] The metabolic profiles of LPG and LPQ leaves were also systematically investigated. [Copyright &y& Elsevier]
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- 2014
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11. Quality consistency evaluation of commercial Impatiens Caulis by integrating UPLC-QTOF-MS/MS chemical profiling and UPLC-DAD multi-components quantification approaches.
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Zeng, Ting, Zhou, Shan-Shan, Xu, Jin-Di, Lin, Xing-Yu, Zhu, He, Li, Song-Lin, and Kong, Ming
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IMPATIENS , *TIME-of-flight mass spectrometry , *QUADRUPOLE ion trap mass spectrometry , *LIQUID chromatography , *PHENOLIC acids , *HERBAL medicine - Abstract
• UPLC-QTOF-MS/MS based chemical profiling was firstly developed for qualitatively characterizing the Impatiens Caulis sample. • A sensitive UPLC-DAD method was firstly developed to quantify eleven compounds in the Impatiens Caulis sample. • The developed method was integrated to compare the quality consistency of commercial Impatiens Caulis samples. In this study, ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS/MS) and ultra-high performance liquid chromatography coupled with photo-diode array spectrometry (UPLC-DAD) were firstly integrated to qualitatively characterize the chemical profiles and quantitatively determine the major components in Impatiens Caulis (IC), a Chinese medicinal herb derived from the dried stem of Impatiens balsamina. The qualitative analysis revealed that there was no difference in chemical profiles of twenty commercial IC samples. A total of 45 components were characterized, there in 5 naphthoquinones, 3 coumarins, 5 phenolic acids, 12 flavonoids and 3 other compounds were identified definitely. However, the quantitative results showed a significant difference in these IC samples. In particular, the highest content of total quantified compounds was even 9.49 times of the lowest one. Furthermore, the average contents of these quantified compounds in twenty commercial IC samples had high values of relative standard deviation (RSD) ranged from 15.64% to 98.76%, suggesting a poor quality consistency in these commercial IC samples. Therefore, efficacy related chemical markers as well as the cultivation region, harvest time and/or post-harvest handling of IC should be further investigated for ensuring its quality and efficacy consistency. [ABSTRACT FROM AUTHOR]
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- 2022
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12. Integrating multiple-chromatographic approaches to evaluate chemical consistency of Chang-Kang-Fang preparations from mixed-herb decoction and combined single-herb decoction.
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Fan, Yan-Ting, Zhong, Ping, Xu, Jin-Di, Zhou, Shan-Shan, Kong, Ming, Zhou, Gui-Rong, Mao, Qian, and Li, Song-Lin
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BERBERINE , *SMALL molecules , *MONOSACCHARIDES , *MOLECULAR weights , *IRRITABLE colon , *CHINESE medicine , *SACCHARIDES - Abstract
[Display omitted] • Multi-chromatographic approaches were integrated to compare chemical profiles between MHD and cSHD. • Polysaccharides and small molecules were qualitatively identical between MHD and cSHD. • The contents of albiflorin, paeoniflorin and alkaloids in MHD were lower than those in cSHD. • The content of polysaccharides in MHD was higher than that in cSHD. Chang-Kang-Fang formula (CKF), a multi-herbs traditional Chinese medicine (TCM) prescription for treating irritable bowel syndrome (IBS), has been clinically applied in the traditional form of mixed-herb decoction (MHD), or in the modern form of combined single-herb decoction (cSHD, so called dispensing granule decoction) in the near decades, but the chemical consistency between the MHD and cSHD is still unknown. Herein, a new strategy by integrating multiple-chromatographic approaches to characterize both polysaccharides and small molecules was developed to compare the chemical consistency between MHD and cSHD. Sixteen small molecules were simultaneously qualified and quantified by UPLC-QTOF-MS/MS, the molecular weight distribution of polysaccharides was characterized by HPGPC-ELSD, while the monosaccharide composition and total saccharides content were determined by HPLC-PDA and UV-VIS, respectively. It was found that the molecular weight range and monosaccharide composition of polysaccharides, as well as the composition of small molecules, were identical between MHD and cSHD. However, the contents of berberine, epiberberine, coptisine, palmatine, albiflorin and paeoniflorin in MHD were significantly lower than those in cSHD, whereas the content of polysaccharides in MHD was higher than that in cSHD, indicating that there is a significant difference in the quality between MHD and cSHD, in particular for the relative contents of major small molecules and polysaccharides. Whether or not these quality variations affect the efficacy and safety of CKF deserves further investigation. [ABSTRACT FROM AUTHOR]
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- 2021
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13. Quality consistency evaluation on four origins of Cicadae Periostracum by ultra-performance liquid chromatography coupled with quadrupole/time-of-flight mass spectrometry analysis.
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Cao, Xin-Ci, Zhang, Xiao-Ya, Xu, Jin-Di, Shen, Hong, Zhou, Shan-Shan, Zhu, He, Kong, Ming, Zhang, Wei, Zhou, Gui-Rong, He, Yi, Mao, Qian, and Li, Song-Lin
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TIME-of-flight mass spectrometry , *MASS analysis (Spectrometry) , *CICADAS , *LIQUID chromatography , *SUPERCRITICAL fluid chromatography , *CHINESE medicine - Abstract
• Holistic quality consistency of four origins of Cicadae Periostracum was evaluated by UPLC-TOF-MS/MS. • Thirty-four N -acetyldopamine polymers identified from four origins of Cicadae Periostracum. • The quality of Cryptotympana atrata , Auritibicen flammatus and C. mandrina were consistent with each other, but Platypleura kaempferi not. • The outcomes beneficial for comprehensively utilizing resources and improving standard of Cicadae Periostracum. Cicadae Periostracum, which is derived from the slough of Cicadidae insects, is a commonly used crude drug in traditional Chinese medicine (TCM). As specified in Chinese Pharmacopoeia, Cryptotympana atrata (CA) is the only official species of this crude drug. However, the slough of other three species, i.e., Auritibicen flammatus (AF), Cryptotympana mandrina (CM) and Platypleura kaempferi (PK), have been also used as the origins of Cicadae Periostracum in Chinese herbal market, although whether the quality of these four origins is consistent or not is still unknown. In present study, ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS/MS) was employed to qualitatively and quantitatively compare the chemical profiles of the four origins. Totally, 34 N -acetyldopamine polymers were identified from the four origins, including 4 N -acetyldopamine dimers, 11 N -acetyldopamine trimers, 10 N -acetyldopamine tetramers, and 9 N -acetyldopamine pentamers. AF, CM and PK had similar chemical profiles with that of CA. The contents and compositional ratio of the four types of polymers in CA, AF and CM were consistent with each other, but significantly lower or different in PK. All these results suggested that AF and CM might be considered as the potential resources of Cicadae Periostracum concerning their consistent holistic quality, whereas whether PK could be used as potential origin of Cicadae Periostracum or not need further evaluation for their different compositional ratios and contents of the four types of N -acetyldopamine polymers. This is the first study on chemical profiling and comparison of N -acetyldopamine polymers in four origins of Cicadae Periostracum, which is beneficial for potential resources utilization and quality standard improvement of Cicadae Periostracum. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
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