Search

Your search keyword '"Annie Brûlet"' showing total 4 results
Start Over Author "Annie Brûlet" Journal langmuir
4 results on '"Annie Brûlet"'

1. pH and Temperature Responsive Polymeric Micelles and Polymersomes by Self-Assembly of Poly[2-(dimethylamino)ethyl methacrylate]-b-Poly(glutamic acid) Double Hydrophilic Block Copolymers

Author

Daniel Taton, Willy Agut, Christophe Schatz, Annie Brûlet, Sébastien Lecommandoux, Laboratoire de Chimie des Polymères Organiques (LCPO), Centre National de la Recherche Scientifique (CNRS)-Institut Polytechnique de Bordeaux-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Université de Bordeaux (UB)-Institut de Chimie du CNRS (INC), Laboratoire Léon Brillouin (LLB - UMR 12), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay, Team 3 LCPO : Polymer Self-Assembly & Life Sciences, Centre National de la Recherche Scientifique (CNRS)-Institut Polytechnique de Bordeaux-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Université de Bordeaux (UB)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut Polytechnique de Bordeaux-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Université de Bordeaux (UB)-Institut de Chimie du CNRS (INC), Team 1 LCPO : Polymerization Catalyses & Engineering, Université de Bordeaux (UB)-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Institut Polytechnique de Bordeaux-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), and Université de Bordeaux (UB)-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Institut Polytechnique de Bordeaux-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB)-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Institut Polytechnique de Bordeaux-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)

Subjects
CROSS-LINKING, Polymers, Glutamic Acid, 02 engineering and technology, 010402 general chemistry, Methacrylate, 01 natural sciences, Micelle, Lower critical solution temperature, GENE DELIVERY, Microscopy, Electron, Transmission, AQUEOUS-SOLUTIONS, Polymer chemistry, Electrochemistry, Copolymer, Nanotechnology, Scattering, Radiation, General Materials Science, POLY(2-VINYLPYRIDINIUM)-BLOCK-POLY(ETHYLENE OXIDE), DRUG-DELIVERY, Micelles, Spectroscopy, Aqueous solution, Chemistry, Temperature, POLYPEPTIDE DIBLOCK COPOLYMERS, COACERVATE CORE MICELLES, Surfaces and Interfaces, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Nanostructures, 0104 chemical sciences, Nylons, [CHIM.POLY]Chemical Sciences/Polymers, Isoelectric point, NEUTRON-SCATTERING, Polymersome, Methacrylates, CLICK CHEMISTRY, Self-assembly, 0210 nano-technology, POLYION COMPLEX MICELLES
Abstract

International audience; The aqueous solution behavior of novel polypeptide-based double hydrophilic block copolymers (DHBCs), namely, poly[2-(dimethylamino)ethyl methacrylate]-b-poly(glutamic acid) (PDMAEMA-b-PGA), exhibiting pH- and temperature-responsiveness is presented using a combination of scattering techniques (light and neutron) and transmission electron microscopy. Close to the isoelectric point (IEP), direct or inverse electrostatic polymersomes are generated by electrostatic interactions developing between the two charged blocks and driving the formation of the hydrophobic membrane of the polymersomes, with the latter being stabilized in water by uncompensated charges. Under basic conditions, that is, when PDMAEMA is uncharged, the thermosensitivity of the DHBCs relates to the lower critical solution temperature (LCST) behavior of PDMAEMA around 40 degrees C. As a consequence, at pH = 11 and below this LCST, free chains of DHBC unimers are evidenced, while above the LCST the hydrophobicity of PDMAEMA drives the self-assembly of the DHBCs in a reversible manner. In this case, spherical polymeric micelles or polymersomes are obtained, depending on the PGA block length. These possibilities of variation in size and shape of morphologies that can be achieved as a function of temperature and/or pH variations open new routes in the development of multiresponsive nanocarriers for biomedical applications.

Published
2010
Full Text
View/download PDF

2. Ionic Liquid/Oil Microemulsions as Chemical Nanoreactors

Author

Florence Gayet, Pierre Lavedan, Jean-Daniel Marty, Nancy Lauth-de Viguerie, Chaker El Kalamouni, and Annie Brûlet

Subjects
chemistry.chemical_classification, Ternary numeral system, Chemistry, Analytical chemistry, Ionic bonding, Surfaces and Interfaces, Nanoreactor, Condensed Matter Physics, Toluene, chemistry.chemical_compound, Hydrocarbon, Chemical engineering, Ionic liquid, Electrochemistry, General Materials Science, Microemulsion, Imide, Spectroscopy
Abstract

The phase diagram and microstructure of the ternary system ionic, liquid benzylpyridinium bis(trifluoromethanesulfonyl)imide)/nonionic surfactant (octylphenol ethoxylate)/toluene, were studied by using conductivity measurements, dynamic light scattering, pulse field gradient spin-echo NMR, and small-angle neutron scattering. Three microregions were identified by conductivity measurements according to the percolation theory. The sizes of IL-in-oil microemulsions with various IL fractions were then determined by NMR and DLS and were found to be in accordance with the radii of gyration (approximately 2 or 3 nm) determined by SANS. The reverse IL-in-oil microemulsions were used as nanoreactors to perform a Matsuda-Heck reaction between p-methoxyphenyl diazonium salt and 2,3-dihydrofurane in the presence of a palladium catalyst. The reaction yields obtained were greater in microemulsions (67%) than in bulk IL (33%), highlighting a strong effect of confinement. Moreover, a direct correlation between the quantity of IL and the reaction yield was observed.

Published
2009
Full Text
View/download PDF

3. Thermoresponsive Micelles from Jeffamine-b-poly(<scp>l</scp>-glutamic acid) Double Hydrophilic Block Copolymers

Author

Sébastien Lecommandoux, Willy Agut, Annie Brûlet, Daniel Taton, Laboratoire de Chimie des polymères organiques (LCPO), Centre National de la Recherche Scientifique (CNRS)-École Nationale Supérieure de Chimie et de Physique de Bordeaux (ENSCPB)-Université Sciences et Technologies - Bordeaux 1-Institut de Chimie du CNRS (INC), Laboratoire Léon Brillouin (LLB - UMR 12), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay, Team 1 LCPO : Polymerization Catalyses & Engineering, Laboratoire de Chimie des Polymères Organiques (LCPO), Centre National de la Recherche Scientifique (CNRS)-Institut Polytechnique de Bordeaux-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Université de Bordeaux (UB)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut Polytechnique de Bordeaux-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Université de Bordeaux (UB)-Institut de Chimie du CNRS (INC), Team 3 LCPO : Polymer Self-Assembly & Life Sciences, Université Sciences et Technologies - Bordeaux 1 (UB)-École Nationale Supérieure de Chimie et de Physique de Bordeaux (ENSCPB)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), and Université de Bordeaux (UB)-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Institut Polytechnique de Bordeaux-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB)-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Institut Polytechnique de Bordeaux-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)

Subjects
02 engineering and technology, 010402 general chemistry, 01 natural sciences, Lower critical solution temperature, Micelle, DELIVERY, chemistry.chemical_compound, Colloid, Dynamic light scattering, Polymer chemistry, Electrochemistry, Copolymer, SCATTERING, WATER, AQUEOUS-MEDIA, General Materials Science, Propylene oxide, DRUG, N-CARBOXYANHYDRIDES, Spectroscopy, SMALL-ANGLE NEUTRON, Ethylene oxide, Surfaces and Interfaces, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 0104 chemical sciences, POLYMERIZATION, DIBLOCK COPOLYMERS, [CHIM.POLY]Chemical Sciences/Polymers, chemistry, Polymerization, 0210 nano-technology
Abstract

National audience; Double hydrophilic block copolymers (DHBC) consisting of a Jeffamine block, a statistical copolymer based on ethylene oxide and propylene oxide units possessing a lower critical solution temperature (LCST) of 30 degrees C in water, and Poly(L-glutamic acid) as a pH-responsive block were synthesized by ring-opening polymerization of gamma-benzyl-L-glutamate N-carboxyanhydride using an amino-terminated Jeffamine macroinitiator, followed by hydrolysis. This DHBC proved thermoresponsive as evidenced by dynamic light scattering and small-angle neutron scattering experiments. Spherical micelles with a Jeffamine core and a poly(L-glutamic acid) corona were formed above the LCST of Jeffamine. The size. of the core of such micelles decreased with increasing temperature, with complete core dehydration being achieved at 66 degrees C. Such behavior, commonly observed for thermosensitive homopolymers forming mesoglobules, is thus demonstrated here for a DHBC that self-assembles to generate thermoresponsive micelles of high colloidal stability.

Published
2007
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results