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1. [Evaluating the mitochondrial dna copy number in leukocytes and adipocytes from metabolic syndrome patients: pilot study].

Author

Mozheĭ OI, Zatolokin PA, Vasilenko MA, Litvinova LS, Kirienkova EV, and Mazunin IO

Subjects
Adipose Tissue physiology, Adult, Aged, Body Mass Index, Case-Control Studies, DNA, Mitochondrial blood, Female, Humans, Male, Middle Aged, Obesity genetics, Pilot Projects, Young Adult, Adipocytes physiology, DNA Copy Number Variations, DNA, Mitochondrial genetics, Metabolic Syndrome genetics
Abstract

The metabolic syndrome is a complex of metabolic, hormonal and clinical disorders. Defects in mitochondrial functions play an important role in the metabolic syndrome pathogenesis. Here, mitochondrial DNA (mtDNA) copy number variations were evaluated different fat tissue and peripheral blood leukocyte samples from metabolic syndrome patients ranked by, body mass indexes. It was elucidated a tendency in decreasing the mtDNA copy number with increasing a body mass index.

Published
2014

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