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Your search keyword '"Oncogenes -- Properties"' showing total 2 results
Start Over Descriptor "Oncogenes -- Properties" Journal nature
2 results on '"Oncogenes -- Properties"'

1. PVT1 dependence in cancer with MYC copy-number increase

Author

Tseng, Yuen-Yi, Moriarity, Branden S., Gong, Wuming, Akiyama, Ryutaro, Tiwari, Ashutosh, Kawakami, Hiroko, Ronning, Peter, Reuland, Brian, Guenther, Kacey, Beadnell, Thomas C., Essig, Jaclyn, Otto, George M., O'Sullivan, M. Gerard, Largaespada, David A., Schwertfeger, Kathryn L., Marahrens, York, Kawakami, Yasuhiko, and Bagchi, Anindya

Subjects
Genetic aspects, Properties, Oncogenes -- Properties, Cancer cells -- Genetic aspects, Breast tumors -- Genetic aspects
Abstract

'Gain' of supernumerary copies of the 8q24.21 chromosomal region has been shown to be common in many human cancers (1-13) and is associated with poor prognosis (7,10,14). The well-characterized myelocytomatosis [...]

Published
2014

2. SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

Author

Barber, Matthew F., Michishita-Kioi, Eriko, Xi, Yuanxin, Tasselli, Luisa, Kioist, Mitomu, Moqtaderi, Zarmik, Tennen, Ruth I., Paredes, Silvana, Young, Nicolas L., Chen, Kaifu, Struhl, Kevin, Garcia, Benjamin A., Gozani, Or, Li, Wei, and Chua, Katrin F.

Subjects
Research, Properties, Oncogenes -- Properties, Genetic transformation -- Research, Acetylation -- Research
Abstract

Sirtuin proteins regulate diverse cellular pathways that influence genomic stability, metabolism and ageing (1,2). SIRT7 is a mammalian sirtuin whose biochemical activity, molecular targets and physiological functions have been unclear. [...]

Published
2012
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