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Chromatin structure and transcription factor localization can be assayed genome-wide by sequencing genomic DNA fractionated by protein occupancy or other properties, but current technologies involve multiple steps that introduce bias and inefficiency. Here we apply a single-molecule approach to directly sequence chromatin immunoprecipitated DNA with minimal sample manipulation. This method is compatible with just 50 pg of DNA and should thus facilitate charting chromatin maps from limited cell populations. [ABSTRACT FROM AUTHOR]

The author discusses data visualization techniques to support data exploration. He particularly talks on the use of graphical representation of data to improve pattern discovery. He mentions the two uses of data visualization which are to communicate research results and to guide the data exploration process as the scientific story unfolds. Furthermore, he explains patterns, data exploration, and Anscombe's quartet.