Search

Your search keyword '"Gao, Pin"' showing total 19 results
Start Over Author "Gao, Pin" Journal organic letters
19 results on '"Gao, Pin"'

8. Direct C–H Cyanoalkylation of Quinoxalin-2(1H)-ones via Radical C–C Bond Cleavage

Author

Yang, Lin, Gao, Pin, Duan, Xin-Hua, Gu, Yu-Rui, and Guo, Li−Na

Abstract

An efficient synthesis of cyanoalkylated heteroarenes via iron-catalyzed direct C–H cyanoalkylation of heteroarenes has been developed. Structurally diverse cyanoalkyl motifs generated through C–C bond cleavage of cyclobutanone oxime esters have been introduced into quinoxalin-2(1H)-ones, flavone, benzothiazoles, and caffeine in good to excellent yields. Remarkably, less-strained cyclopentanone and unstrained cyclohexanone oxime esters were also amenable substrates in this cyanoalkylation reaction.

Published
2024
Full Text
View/download PDF

14. Fe-Catalyzed Alkylazidation of α-Trifluoromethylalkenes: An Access to Quaternary Stereocenters Containing CF3and N3Groups

Author

Liu, Shuai, Zhang, Lu, Xu, Liang, Gao, Pin, Duan, Xin-Hua, and Guo, Li−Na

Abstract

A concise Fe-catalyzed alkylazidation of α-trifluoromethylalkenes via a C–C bond cleavage/radical addition/azidation cascade is described. This protocol features a broad substrate scope, excellent functional group compatibility, and the ability to be performed on a gram scale, thus offering a practical and step-economic approach to the synthetically useful tertiary α-trifluoromethyl azides.

Published
2023
Full Text
View/download PDF

16. Switchable In SituSO2Capture and CF3Migration of Enol Triflates with Peroxyl Compounds under Iron Catalysis

Author

Shan, Qi-Chao, Liu, Shuai, Shen, Yuncheng, Ma, Mingming, Duan, Xin-Hua, Gao, Pin, and Guo, Li-Na

Abstract

Switchable in situSO2capture and CF3migration of enol triflates with peroxyl compounds under iron catalysis are presented. By regulating the structure of peroxides, a variety of keto-functionalized dialkyl sulfones and α-trifluoromethyl ketones were selectively synthesized in good yields under mild conditions.

Published
2022
Full Text
View/download PDF

17. Fe-Catalyzed Alkylazidation of α-Trifluoromethylalkenes: An Access to Quaternary Stereocenters Containing CF 3 and N 3 Groups.

Author

Liu S, Zhang L, Xu L, Gao P, Duan XH, and Guo LN

Abstract

A concise Fe-catalyzed alkylazidation of α-trifluoromethylalkenes via a C-C bond cleavage/radical addition/azidation cascade is described. This protocol features a broad substrate scope, excellent functional group compatibility, and the ability to be performed on a gram scale, thus offering a practical and step-economic approach to the synthetically useful tertiary α-trifluoromethyl azides.

Published
2023
Full Text
View/download PDF

18. Switchable In Situ SO 2 Capture and CF 3 Migration of Enol Triflates with Peroxyl Compounds under Iron Catalysis.

Author

Shan QC, Liu S, Shen Y, Ma M, Duan XH, Gao P, and Guo LN

Abstract

Switchable in situ SO 2 capture and CF 3 migration of enol triflates with peroxyl compounds under iron catalysis are presented. By regulating the structure of peroxides, a variety of keto-functionalized dialkyl sulfones and α-trifluoromethyl ketones were selectively synthesized in good yields under mild conditions.

Published
2022
Full Text
View/download PDF

19. Iminyl Radical-Triggered Intermolecular Distal C(sp 3 )-H Heteroarylation via 1,5-Hydrogen-Atom Transfer (HAT) Cascade.

Author

Gu YR, Duan XH, Chen L, Ma ZY, Gao P, and Guo LN

Abstract

An efficient iron-catalyzed intermolecular remote C(sp 3 )-H heteroarylation of alkyl ketones has been developed via an iminyl radical-triggered 1,5-hydrogen-atom transfer (HAT) cascade. This protocol was amenable to a wide variety of alkyl ketones and heteroaryls, thus providing a straightforward method for the late-stage functionalization of alkylketones and heteroaryls.

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results