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Start Over Author "Xuerong Cai" Journal organic process research & development
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1. Development of a Robust and Scalable Process for the Large-Scale Preparation of Vadadustat

Author

Zhongqing Wang, Xiao Qingbo, Li Yinglong, Shuming Wu, Hu Ji'an, Jianbing Li, Lin Biyue, Jingping Kou, and Xuerong Cai

Subjects
010405 organic chemistry, business.industry, Computer science, Scale (chemistry), Organic Chemistry, Process (computing), Vadadustat, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, Scalability, Physical and Theoretical Chemistry, Process engineering, business
Abstract

A novel and scalable process is developed for the industrial synthesis of vadadustat. The four-step process is one step shorter compared to the reported routes with an increase in total yield to 49...

Published
2021
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