Search

Objective: To evaluate the effectiveness of employing Foley's catheter and modified thermal balloon ablation to treat heavy menstrual bleeding (HMB). Study Design: Prospective Interventional Randomized Control study. Setting: Departments of Gynecological of Three Semi Government Hospitals of the City. Period: January 2021 to September 2022. Material & Methods: In the study, 12 patients between the ages of 42 and 50 who complained of menorrhagia and who had not responded to treatment for at least 6 months were recruited. Pre-ablation endometrial curettage was performed on each patient. A 30-50 ml latex covered Foley's Catheter was evaluated after being introduced into uterine cavity, inflated as much as the cavity would allow under moderate pressure, and changed every two minutes with fresh boiling saline for eight minutes. Following that, hysteroscopic examination and a 6-month follow-up were performed to look for endometrial scarring. Results: Significantly shorter hospital stays, shorter recovery times following surgery, and quicker return to normal daily and sexual activities. Regarding problems, menstrual alterations, amenorrhea rate, and failure rate during the course of follow-up, there was no discernible difference between patients. This method has a success rate of almost 88%. Conclusion: In situations with limited resources, improved thermal balloon ablation with a Foley's catheter can be a potential treatment for HMB. It is a more affordable option that the preliminary endometrial ablation approaches. [ABSTRACT FROM AUTHOR]

Objective: To evaluate the efficacy of clomiphene citrate compared with clomiphene citrate and metformin combination used as infertility treatment in polycystic ovarian syndrome. Study Design: Randomized Controlled study. Setting: Combined Military Hospital, Nowshera, KPK. Period: March 2021 to November 2021. Material & Methods: One hundred and forty eight infertile patients aged between 20 to 34 years diagnosed with PCOS were enrolled for the investigation. Using blocked randomization technique, the participants were divided into two groups. Group A patients received clomiphene citrate 50 mg day on days 2 to 6 and dose was gradually increased to 150 mg day. Patients in Group B received metformin 500 mg three times a day along with the above mentioned dosage of clomiphene citrate. Collectively, the patients in both groups were provided with a follow up for six months. Efficacy in both groups was assessed on the basis of positive urine pregnancy test. Results: The rate of ovulation in group B was high in comparison to group A (39.2%vs 21.6%; P value = 0.02) the results were statistically significant. The rate of efficacy/conception in group B was significantly greater as compared to group A (32.4%vs 16.2%; P value = 0.02). Conclusion: We conclude that clomiphene citrate along with metformin, used in combination is significantly much efficacious as compared to clomiphene citrate alone for treating infertility in patients with polycystic ovarian syndrome. [ABSTRACT FROM AUTHOR]