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Your search keyword '"*ANTIGENS"' showing total 2 results
Start Over "*ANTIGENS" Topic antigens Publication Year Range More than 50 years ago Journal scandinavian journal of dental research
2 results on '"*ANTIGENS"'

1. Immune adherence with keratinized human oral mucosa and human serum.

Author

Kristoffersen, Tore and Krogh, Hans-Kristian

Subjects
*SERUM, *IMMUNOGLOBULINS, *ANTIGENS, *SKIN, *KERATOSIS, *GINGIVA
Abstract

All normal human sera examined have been shown to contain complement-fixing antibody to an antigen present in stratum corneum of human skin. By immune adherence with human sera and sections of frozen biopsy specimens, the antigen was found to be present in sections of keratotic and parakeratotic areas of human gingiva, tongue, alveolar, buccal, and palatal mucosa. Serum from biopsy donors mediated the adherence reaction. Absorption with a phenol-water extract (water phase) of stratum corneum of skin removed the antibodies. The antigen was not detected in non-keratinized areas of human oral mucosa, including gingival crevice and cuff epithelium. Erythrocytes also adhered to keratinized epithelium in gingival biopsy specimens fixed in ethanol and cleared in xylene at 4° C prior to sectioning and incubation with human serum. [ABSTRACT FROM AUTHOR]

Published
1971
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2. Immune adherence with keratinized human oral mucosa and human serum

Author

Hans-Kristian Krogh and Tore Kristoffersen

Subjects
Pathology, medicine.medical_specialty, Erythrocytes, Time Factors, Biopsy, Gingiva, Human skin, Biology, In Vitro Techniques, Antibodies, Antigen, Tongue, medicine, Stratum corneum, Methods, Humans, Oral mucosa, Antigens, General Dentistry, Immune adherence reaction, Skin, integumentary system, medicine.diagnostic_test, Palate, Complement Fixation Tests, Immune adherence, Mouth Mucosa, Buccal administration, Immune Adherence Reaction, medicine.anatomical_structure, Blood, Immunology, Keratins
Abstract

– All normal human sera examined have been shown to contain complement-fixing antibody to an antigen present in stratum corneum of human skin. By immune adherence with human sera and sections of frozen biopsy specimens, the antigen was found to be present in sections of keratotic and parakeratotic areas of human gingiva, tongue, alveolar, buccal, and palatal mucosa. Serum from biopsy donors mediated the adherence reaction. Absorption with a phenol-water extract (water phase) of stratum corneum of skin removed the antibodies. The antigen was not detected in non-keratinized areas of human oral mucosa, including gingival crevice and cuff epithelium. Erythrocytes also adhered to keratinized epithelium in gingival biopsy specimens fixed in ethanol and cleared in xylene at 4° C prior to sectioning and incubation with human serum.

Published
1971

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