1. Image denoising of low-radiation dose coronary CT angiography by an adaptive block-matching 3D algorithm
- Author
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Jonghye Woo, Ryo Nakazato, Daniel S. Berman, C.-C. Jay Kuo, Piotr J. Slomka, Damini Dey, and Dongwoo Kang
- Subjects
Matching (graph theory) ,medicine.diagnostic_test ,Computer science ,Noise reduction ,Angiography ,Image noise ,medicine ,Low dose ct ,Coronary ct angiography ,Image denoising ,Algorithm ,Block (data storage) - Abstract
Our aim in this study was to optimize and validate an adaptive denoising algorithm based on Block-Matching 3D, for reducing image noise and improving assessment of left ventricular function from low-radiation dose coronary CTA. In this paper, we describe the denoising algorithm and its validation, with low-radiation dose coronary CTA datasets from 7 consecutive patients. We validated the algorithm using a novel method, with the myocardial mass from the low-noise cardiac phase as a reference standard, and objective measurement of image noise. After denoising, the myocardial mass were not statistically different by comparison of individual datapoints by the students' t-test (130.9±31.3g in low-noise 70% phase vs 142.1±48.8g in the denoised 40% phase, p= 0.23). Image noise improved significantly between the 40% phase and the denoised 40% phase by the students' t-test, both in the blood pool (p
- Published
- 2013
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