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Abstract: Chiral C 2-symmetric diphenylthiophosphoramide ligand L1 prepared from C 2-symmetric (1S,2S)-(−)-1,2-diphenylethylenediamine was found to be a fairly effective chiral ligand for Cu(I)-promoted 1,3-dipolar cycloaddition of imines and pyrrole-2,5-dione derivatives to give the corresponding adducts in moderate enantioselectivities and good yields. [Copyright &y& Elsevier]

In the presence of a catalytic amount of chiral imino-thiophosphoramide ligand L7 (6 mol %) and Cu(I) salt (3 mol %), the asymmetric addition of diethylzinc to α,β-unsaturated carbonyl compounds could be achieved in good yields with moderate ees (up to 75% ee) at −20 °C in toluene. A novel chiral imino-thiophosphoramide ligand system for this asymmetric 1,4-addition reaction has been explored. [Copyright &y& Elsevier]

The axially dissymmetric chiral Schiff base ligand 10, prepared by the reaction of (R)-(+)-1,1′-binaphthyl-2,2′-diamine with (R)-(+)-2,2′-dihydroxy-[1,1′]-binaphthalenyl-3-carbaldehyde, is a fairly effective chiral ligand for the catalytic asymmetric addition reaction of diethylzinc to aldehydes. [Copyright &y& Elsevier]

Abstract: Axially chiral phosphine–oxazoline ligand L7, prepared from (S)-binol, was found to be a fairly effective chiral ligand in the silver(I)-catalyzed asymmetric Mannich reaction of fluorinated aldimines with trimethylsiloxyfuran to give the corresponding adducts in up to 99% yield, over 20:1 dr and 81% ee. [Copyright &y& Elsevier]

Abstract: Enantioselective allylic substitution of Morita–Baylis–Hillman (MBH) acetates with phthalimide was realized in the presence of a novel l-proline-derived chiral trifunctional phosphine amide ligand to give the corresponding allylic amination adducts in good yields (70–95%) and in modest to good enantioselectivities (34–78% ee’s). [Copyright &y& Elsevier]

Abstract: Axially chiral imine ligands derived from (R)-BINAM are effective chiral ligands in the Zn(OTf)2-promoted enantioselective Friedel–Crafts alkylation of indoles with nitroalkenes under mild conditions to give the corresponding adducts in good yields and moderate enantioselectivities. [Copyright &y& Elsevier]

Abstract: Chiral phosphine-Schiff base type ligand L3 prepared from (R)-(−)-2-(diphenylphosphino)-1,1′-binaphthyl-2′-amine was found to be a fairly effective chiral ligand for the Pd(II)-catalyzed and diethylzinc-mediated enantioselective umpolung allylation of aldehydes to give homoallylic alcohols in good yields, moderate enantioselectivities and high syn diastereoselectivities. [ABSTRACT FROM AUTHOR]

Abstract: Chiral phosphine-Schiff base-type ligand L1 prepared from (R)-(−)-2-(diphenylphosphino)-1,1′-binaphthyl-2′-amine was found to be a fairly effective ligand for Cu(I)-promoted enantioselective α-hydroxylation of β-keto esters using oxaziridine 2a as the oxidant to give the corresponding products in high yields along with moderate enantioselectivities. [Copyright &y& Elsevier]