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This position paper prepared by the Japanese Working Group on Integrated Nutrition for Dysphagic People (JWIND) aims to summarize the need for nutritional management in adult patients with dysphagia, the issues that nutrition professionals should address, and the promising approaches as well as to propose a vision for the future of nutritional care for adult patients with dysphagia. JWIND is a joint certification system recognized by the Japan Dietetic Association and the Japanese Society of Dysphagia Rehabilitation; its members are mostly experts known as "Certified Specialist of Registered Dietitian for Dysphagia Rehabilitation." Malnutrition and dysphagia are associated with each other. Therefore, malnutrition detection and intervention are essential for patients with dysphagia. However, evidence on the usefulness nutritional assessment and intervention to ensure appropriate nutritional care remains insufficient. Here, we present current knowledge of the relationship between primary diseases causing dysphagia and malnutrition, the indicators used for nutritional assessment, and nutritional interventions such as texture-modified diet (TMD) quality improvement, oral nutritional supplementation, and comprehensive intervention. We also discuss the current status and issues in nutritional care for adult patients with dysphagia. Furthermore, we have proposed measures that nutrition professionals should consider based on 3 perspectives: nutritional assessment, TMD, and nutritional intervention. Individualized and specialized nutritional management by registered dietitians (RDs) through appropriate assessment of the nutritional status of adult patients with dysphagia is needed. To maintain and improve swallowing function and nutritional status, RDs should intervene from the state of risk or early dysphagia onset, providing individualized care per their expertise as part of a multidisciplinary team. However, systematic clinical practice and research regarding the association of nutrition with dysphagia are currently insufficient. Therefore, further clinical practice and evidence building, including the verification of the efficacy on nutritional support through intervention research, are needed. [ABSTRACT FROM AUTHOR]

Travertines are hot spring carbonate deposits that exhibit characteristic fabrics, including a paper-thin raft and a coated bubble formed by the calcification of water and bubble surfaces, respectively. A previous study interpreted that compared with the water surface, the bubble surface displays more active CO 2 degassing and resultant active CaCO 3 precipitation. However, considering the CO 2 partial pressure and the volumes of atmosphere and bubbles, it is possible that more active CO 2 degassing occurs on the water surface. In addition, the surfaces of water and bubbles at the travertine-depositing sites are negatively charged, but it is still unclear whether the CaCO 3 nucleation on these surfaces occurs via amorphous precursors, like the CaCO 3 nucleation on negatively charged organic matter. This study provides a solution to these uncertainties by examining the aragonitic travertines formed in the Nagayu area of Japan. Through field observations, two types of paper-thin rafts were recognized: one with a smooth surface and formed in approximately 1 h, and the other with a rough surface and formed in approximately 3 h. In addition, the bubbles generated on the microbial mat during the daytime were covered with white minerals within an hour, and with ivory-colored minerals over 8 h after sunset, forming firm coated bubbles. Microelectrode measurements revealed that the active CO 2 degassing on the water surface significantly increased the CaCO 3 saturation state to cause active CaCO 3 precipitation. In contrast, less active CO 2 degassing on the bubble surface did not increase the saturation state, and moderate CaCO 3 precipitation occurred due to the moderately high saturation state of the hot spring water. Various microscopic observations revealed that the smooth-surfaced paper-thin raft comprises a micritic layer of approximately 10–20 μm, which represents tightly arranged submicron-sized granular aragonite. At the lower surface of this layer, hemispherical aragonite partially grew toward the hot spring water. In addition, the rough-surfaced paper-thin raft and coated bubble comprise bundled and acicular aragonites arranged along the surfaces of water and bubble, from which hemispherical aragonite grew toward the hot spring water. Neither the paper-thin raft nor the coated bubble contains primary amorphous CaCO 3. These results suggest that the smooth-surfaced paper-thin raft is formed by active CaCO 3 nucleation on the water surface and subsequent crystal growth, and that the water surface is unfavorable for preserving the amorphous precursors potentially involved in the nucleation. The rough-surfaced paper-thin raft and the coated bubble could have been formed by the attachment of externally formed acicular aragonite to the water/bubble surface and subsequent crystal growth. The revealed formation processes of the paper-thin raft and coated bubble provide valuable information for interpreting their formation mechanism in other travertine deposits, including those in the geological past. [ABSTRACT FROM AUTHOR]

Numerous socio-legal factors make the process of surrogate decision-making for people living in dementia very complicated in Japan. In this discussion paper, we argue that the lack of early consultation between patients, surrogate decision-makers and healthcare providers and the overreliance of patients and their families on doctors to assume the decision-making role lead to healthcare practices that may not align with the patient's wishes. Further, we argue that lack of laws on surrogate decision-making, changing family structure and the liabilities associated with the care of people living with dementia contribute to the complexity of the decision-making process in Japan. Finally, given the rapidly changing social and healthcare norms in Japan, we call for greater involvement of nurses and care workers in the decision-making process to ensure patient-centric treatment and care are adopted. [ABSTRACT FROM AUTHOR]

• Concentrations of product gases CO, H 2 , and hydrocarbons varied by feedstock. • Concentrations of CH 4 and tar were similar for different feedstocks. • Higher ER showed lower tar concentration. It ranged 2.5–14.0 g/Nm3 -dry. • ER of 0.4 was an optimal gasification condition for a GE power generation. Energy recovery from small and medium scale waste thermal treatment facilities in the municipalities of Japan is challenging, owing to low power generation efficiency and high economic demands. Gas Engine (GE) generation is considered an efficient resource utilization method in these facilities. In this study, new and consistent feedstock, Refuse Paper and Plastic Fuel (RPF), and wood pellets were tested in an air-blown Fluidized Bed Gasifier (FBG) for syngas utilization in a GE. With temperatures ranging from 700 to 940 °C and varying Equivalence Ratios (ER) of 0.3–0.5, some of the most important product gas characteristics were analyzed, including the Lower Heating Value (LHV) and tar concentration levels. Gas composition results revealed that the concentration tendencies varied for the product gases CO, H 2 , and hydrocarbons, depending on the feedstock type, whereas the same tendencies were observed for CH 4 and tar concentrations. Through the ER range, the LHV of product gas for RPF and wood pellets was 3.4–5.9 MJ/Nm3. Tar concentrations decreased to 2.5–14.0 g/Nm3 -dry as the ER was raised. The optimal ER for LHV performance in GE generation was approximately 0.4 for RPF and wood pellets, and remaining tar concentrations were about 5.0 g/Nm3 -dry at the gasifier exit. [ABSTRACT FROM AUTHOR]

The increasing presence of e-books (electronic books) has become a major focus in countries around the world. In the United States, e-books represented 28% of the total book sales for 2012. In Japan, the conversion from paper books to e-books is expected to accelerate by the prevalent use of smartphones and tablet PCs. It is therefore important to quantitatively evaluate the environmental load of paper books and e-books for a sustainable society. In this study, paper books are compared to e-books read on different electronic devices (e-ink tablets, tablets, cell phones, smartphones, laptop computers, desktop computers and portable music players) through a case study on a 224-page book. The study is based on key primary data such as use time and reading speed for each device and aims to minimize assumptions made in other studies. GHG emissions for paper books are 1.24 kg-CO 2 e/book, and are reduced to 1.11 kg-CO 2 e/book when the effect of paper recycling is taken into consideration. The results for e-books under average use-time conditions range from 0.25 to 0.91 kg-CO 2 e/book with the e-ink tablet having the lowest emissions. When the average use time of each e-book device is applied, the paper book has a higher impact than all the e-books. However, sensitivity analysis shows that the impact of paper books can be lower than that of e-books for larger screen devices such as tablets, laptops and desktops when the reuse of books is considered or the e-book reading device is hardly used during its life cycle. [ABSTRACT FROM AUTHOR]

We conducted an event study on the concealment of the blending ratio of waste paper with virgin pulp in Japan. By investigating 10 companies in the paper industry between May 30, 2007 and January 18, 2008, we clearly show that stock prices of the relevant companies were affected by the news on the concealment of the blending ratio of waste paper. In addition, the impact of the second event was found to be greater than that of the first event. Therefore, the concealment of major companies negatively affects the stock prices of non-major companies, which did not conceal information during this period. Thus, bad news is negatively assessed by the market, and this influence has spread in the paper industry in general. [Copyright &y& Elsevier]

Abstract: A novel carbon paper has been prepared by pyrolysis from traditional Japanese paper called washi in Japan, which is mainly composed of cellulose microfibers. The washi was iodine-treated before pyrolysis. The effect of iodine-treatment on pyrolysis of the washi was investigated using thermogravimetric analysis. The structural and electrical properties of the carbon papers were also investigated using Raman scattering, X-ray diffraction, electron microscopy, and resistivity measurements. The iodine-treatment prevents cellulose from thermally decomposing and is effective in increasing the carbon yield and retaining its fibrillar structure. Porous carbon papers consisting of many micro and nanofibrils were prepared by the pyrolysis of the iodine-treated washi at 800°C. Those prepared at 800°C and then heat-treated at higher temperatures than 1800°C show electrical conductivities of 3Scm−1 and 24–27Scm−1. The degree of crystallinity and the electrical conductivity of the papers are improved by the heat treatment at higher temperatures. [Copyright &y& Elsevier]

• Paper sludge ash-based stabilizer (PSAS) is a new type of soil stabilizer. • The W ab and PSD of PSAS influence the change in consistency PSAS-treated soil. • The q c of PSAS-treated soil can be estimated based on its liquidity index I L. • Required PSAS amount for a specific q c of PSAS-treated soil can be estimated. Paper sludge ash-based stabilizers (PSASs) have recently been developed in Japan as sustainable construction materials for soil stabilization. PSASs are produced by the in-solubilization of heavy metals in paper sludge (PS), which is generated as a by-product of the de-inking and re-pulping of paper. PSASs can improve the stability of high-water-content clays immediately after mixing owing to their good water absorption and retention performance. However, mixture design methods that consider time variations of the water absorption and retention performance of a PSAS are lacking. Therefore, in this study, the effects of a PSAS on the physical and mechanical properties of the treated clay were experimentally investigated, considering the change in the water absorption and retention performance of the PSAS with curing time. The water absorption and retention rate, W ab , of the PSAS, is defined as the ratio of the mass of water absorbed and retained by the PSAS to its dry mass. Physical tests and cone index tests were conducted on different types of clays treated with different types of PSASs. The test results showed that different W ab values were obtained depending on the type of the PSAS and that the W ab value increased with curing time. From the experiments, it was found that the liquid limits, w L , and plastic limits, w P , of the PSAS-treated clays with different curing times could be evaluated from the W ab values of the PSAS and the particle sizes of the PSAS and untreated clays. A clear correlation was also found between the cone index, q c , and liquidity index, I L , of the treated and untreated clays. Based on the results, a new approach for mixture design was proposed. The applicability of the proposed method was investigated, and the results showed that the measured q c value of the PSAS-treated clay was close to the target q c value. The average measured q c was approximately 1.1 times the corresponding target q c. The maximum error between the measured q c and target q c values was approximately 30%. [ABSTRACT FROM AUTHOR]

Objective: To investigate changes in the clinical state of taste disorders between 1990, 2003, and 2019 using the same methodology as that in previous studies.Materials and Methods: In June 2019, we mailed a questionnaire to 1100 otolaryngologists belonging to the Japan Society of Stomato-pharyngology and investigated three question categories: "Institution", "Number of patients for 3 months", and "Treatment". In addition, we analyzed some results by the class of institution.Results: The rate of patients who complained of taste disorders in the 2019 survey (220/100,000 persons/year) was twice that of the 1990 survey (110/100,000 persons/year), and slightly higher than that of the 2003 survey (192/100,000 persons/year). The rate of female patients was higher than that of male patients in all age groups. The number of patients was correlated with age up to 70 years of age in both genders. The rates of performing taste tests to assess taste function in the 2019 survey were significantly decreased compared with a 2003 survey (electrogustometry: p<0.001, filter paper disk method: p<0.05 in university). The rate of examination of the serum zinc in the 2019 survey was increased compared with the 1990 survey (p<0.001). Zinc oral therapy was used for the treatment of taste disorders in 239/299 (79.9%) patients/institutes for 3 months. In addition, 213 institutions (69.6%) answered that zinc oral therapy was efficacious for taste disorders.Conclusion: The patients who complained of taste disorder have increased. The zinc administration is an appropriate clinical treatment for taste disorders in Japan. To enhance treatment for taste disorders, simpler methods for assessing taste function need to be developed, and the pathological mechanisms of taste disorders other than zinc deficiency need to be clarified. [ABSTRACT FROM AUTHOR]

Climate change is a significant challenge that the medical community must address. Hospitals are large facilities with high water and energy consumption, as well as high levels of waste generation, which makes it important to pursue green hospital initiatives. Neurosurgery requires substantial energy for surgeries and tests. Based on the keywords "Climate change," "green hospital," "neurosurgery," "energy consumption," "environmental impact" listed in this paper, we extracted representative manuscripts, and the practices employed in the authors' hospital were assessed. The "Guidelines for Environmental Consideration in Hospitals" and "Guidelines for the Sustainability of Hospital Environments" have been developed; however, they are not implemented in most hospitals in Japan. Inhalational anesthetics were found to contribute significantly to greenhouse gas emissions. Educating patients and staff and employing the "8 Rs" (rethink, refuse, reduce, reuse, recycle, research, renovation, and revolution) showed promise in achieving green hospital standards. The advent of 'green hospitals' in Japan is imminent. The active participation of neurosurgeons can play a crucial role in diminishing the environmental footprint of health care while simultaneously enhancing medical standards. Given the pressing challenges posed by climate change, there is a critical need for an overhaul of medical practices. It is imperative for neurosurgeons to pioneer the adoption of new, sustainable medical methodologies. [ABSTRACT FROM AUTHOR]

As the COVID-19 epidemic continues, concerns about long-term health impacts, specifically long COVID, persist. While the prevalence and symptomatology of long COVID have been explored in various global contexts, large-scale cohort studies in Japan remain limited, especially after the advent of the Omicron variant. In this observational study, 4,047 residents with a history of COVID-19 living in Toyonaka City, Osaka Prefecture, were assessed for long COVID symptoms using the VOICE mobile application and a paper survey. Respondents provided demographic and health information, as well as information regarding COVID-19 infection and subsequent symptoms. A Cox proportional hazard regression model was used to estimate the multivariable-adjusted hazard ratios and 95 % confidence intervals for overall morbidity of long COVID symptoms. The survey found that 5.2 % of participants reported the persistence of one or more symptoms at 30 days post-onset. Fatigue was the most commonly reported symptom (1.75 %), followed by hair loss (1.41 %), and cough (1.28 %). Factors associated with an increased risk of experiencing long COVID symptoms included BMI, severe illness during the acute phase, and infection with certain COVID-19 variant strains, including Alpha, Delta, and Omicron. However, the incidence rate of long COVID appears to be decreasing with the dominance of the Omicron variant. This large-scale study from Toyonaka City suggests a 5.2 % prevalence rate for persistent COVID-19 symptoms 4 weeks post-infection, potentially indicating a lower prevalence of long COVID in Japanese populations after the rise of the Omicron variant. [ABSTRACT FROM AUTHOR]

• Human resources development aided the developing space program of the Philippines. • Most of the selected personnel for training came from the academia. • Trainees taken from the industry followed later to support the push for space. • Most of trained personnel opted to stay in the country to support the space program. The Philippines has experienced a shift of interest in space technology development and utilization over the past decade, culminating with the establishment of its national space agency in 2019. In cooperation with different universities in Japan, the Philippines successfully developed and launched two microsatellites, DIWATA-1 and DIWATA-2, and six nanosatellites, MAYA-1 to MAYA-6. By sending personnel to Japan and other space-faring countries, the country was able to rapidly ramp up its satellite development and utilization capabilities. In this paper, we examine and evaluate the complex human resources development efforts conducted by the country to support the creation of a local space ecosystem and ensure its long-term sustainability. Through a careful review, we identify how many people benefited from training programs, studies abroad or other forms of capacity building, and how these skilled individuals were retained in the budding Filipino space sector. Precisely, we looked at the backgrounds of the different people trained by the country, what type of training they received (funding, location, and duration), and how they are supporting the local space ecosystem at the time of writing this paper. [ABSTRACT FROM AUTHOR]

How does a country embark on large-scale R&D programs? Among R&D programs, this is an intriguing question for large scale Science and Technology (S&T) projects such as space programs, because of the necessity for large resource commitments, and the difficulty of being accountable to the taxpayers when the outcome is not always known. It can be assumed that engineers, scientists, bureaucrats, and politicians play respective roles. This paper aims to shed light on the specific role of politics, through the examples of policies of and decisions by NAKASONE Yasuhiro. Nakasone was the minister for science and technology (1959–1960, 1972), and later became the prime minister (1982–1987). He played a crucial role in establishing the Science and Technology Agency and the National Space Activities Council in the 1950s, which would be the foundational institutions responsible for space policy for the next half century. As prime minister, he decided to participate in the Space Station program. Within his vision for Japan for the 21st century, he emphasized the need for radical change in economic policy, education, defense and S&T investment. He was one of the few politicians that had vision to promote S&T and recognized the strategic value to the nation. He was able to explain to the nation why Japan should promote the development of a launch vehicle, when the engineers faced development difficulties in doing so. Thus, he was influential both in the policy layer and in promoting specific programs to support his national vision. Politics intersects with S&T projects because of the uncertainty and tradeoffs associated with these efforts. Japan did not address space programs for national security and commercial space for a long time. It is a politician's role to create institutions, to allocate resources and, more importantly, to explain to the taxpayers why policy measures or programs are necessary. R&D investment is a societal activity: it reflects the social, political, and economic situation, as well as being important for diplomacy and international relations. Bearing in mind that it would be misleading to attribute the initiation of largescale S&T projects to the leadership of a single individual, this paper will attempt to show the driving forces behind, and fundamental objective of Japan's space policy, in addition to the historical shift in that policy by examining the influence of this notable politician. • Nakasone played the key role in establishing institutions promoting space development in post-war Japan. • Nakasone made the best use of close relationships with the U.S. in promoting Japan's space activities. • Nakasone made decisions on space policy process, resource allocation with vision, thus integrating the stakeholders. [ABSTRACT FROM AUTHOR]

Hydrogen energy technologies are envisioned to play a critical supporting role in global decarbonisation. While low-carbon hydrogen is primarily targeted for reducing industrial emissions, alongside decarbonising parts of the transport sector, environmental benefits could also be achieved in the residential context. Presently, gas-dependent countries such as Japan and the United Kingdom are assessing the feasibility of deploying hydrogen home appliances, as part of their national energy strategies. However, prospects for the transition will hinge on consumer acceptance, alongside an array of other socio-technical factors. To support potential ambitions for large-scale and sustained technology diffusion, this study advances a Unified Theory of Domestic Hydrogen Acceptance. Through an integrative, comparative literature review targeting hydrogen and domestic energy studies, the paper proposes a novel Domestic Hydrogen Acceptance Model (DHAM), which accounts for the cognitive and emotional dimensions of human perceptions. Through this dual interplay, the proposed framework can increase the predictive power of hydrogen acceptance models. [Display omitted] • A unified theory of domestic hydrogen acceptance is proposed. • Researchers should integrate multiple acceptance constructs into survey studies. • Comprehensive perceived risks, costs, and benefits predict attitudes toward hydrogen. • Cognitive and emotional processes influence perceptions of hydrogen homes. • Community-level factors should be incorporated into hydrogen acceptance research. [ABSTRACT FROM AUTHOR]

This paper examines whether a forced displacement of an ethnic group can lead to long-run changes to their spatial distribution and whether this shock can also lead to changes in where new migrants settle. I use the Canadian government's internment of Japanese Canadians during World War II, as well as their post-war forced resettlement, as a natural experiment. I find that the policy led to dramatic resettlement patterns; areas where Japanese Canadians were removed from had far fewer Japanese Canadians after World War II, with this effect persisting for decades. Despite these displacement patterns, I find that both the pre-war and post-war settlement patterns drive where new Japanese migrants settle within Canada, suggesting that the disruption of the connections and networks formed by Japanese migrants before World War II were not fully dismantled by the Canadian government's wartime policies. Reinforcing this mechanism, I show using Facebook's social connectedness data that Japanese population shares from both 1931 and 1951 predict whether a Canadian Census Division is more socially connected with Japan today. The results from this paper show that, despite Canada's forced dispersal of its Japanese population across the country, networks and forces that connect Census Divisions to Japan and draw in new migrants continued to persist. [ABSTRACT FROM AUTHOR]

As medical device development becomes increasingly global, the opportunities and potential advantages offered by international clinical trial and regulatory approval strategies are also growing. In particular, medical device clinical trials involving sites in both the United States and Japan and intended to support marketing in both countries may warrant particular consideration, given the similarities in their regulatory systems, patients and clinical practice patterns, and market sizes. Since 2003, the US-Japan Harmonization By Doing (HBD) initiative has been focused on identifying and addressing clinical and regulatory barriers to medical devices access in both countries via collaboration between governmental, academic, and industry stakeholders. Through the efforts of HBD participants, US-Japanese clinical trials have been conducted and the resulting data have supported regulatory approval for marketing in both countries. Based on these experiences, this paper outlines some of the key factors to consider when developing a global clinical trial involving US and Japanese participation. These considerations include the mechanisms for consultation with regulatory authorities on clinical trial strategies, the regulatory framework for clinical trial notification and approval, recruitment and conduct of clinical sites, and lessons learned from specific US-Japanese clinical trial experiences. The goal of this paper is to promote global access to promising medical technologies by assisting potential clinical trial sponsors in understanding when an international strategy may be appropriate and successful. • Perspectives on how to maximize opportunities for global clinical trials for medical devices • US and Japanese regulatory processes for device clinical study consultations and applications • Lessons from actual US-Japanese clinical trials supporting cardiovascular device approval • Leveraging existing multi-stakeholder collaborations via Harmonization by Doing (HBD) program [ABSTRACT FROM AUTHOR]

With rapid industrialization, rising fossil fuel consumption, and environmental concerns, developing clean and green energy is an inescapable option. Hydrogen has emerged as a significant potential energy carrier and a viable future replacement fuel for fossil fuels due to its renewable and pollution-free properties. Previous review papers have significantly contributed to the body of literature on the various technologies for producing hydrogen by revealing key insights into their working principles and conditions, as well as the economic and environmental aspects. In addition, they also highlighted the potential pathways to enable the application of these technologies in the context of carbon neutrality. However, these studies have not broken down the evolutionary patterns and developmental progress of either fossil fuel-based or renewable energy-based technologies used to produce hydrogen. In addition, the currently available literature does not contain the most recent research that focuses on the evolution and life cycle of each technology category from a chronological point of view. The key drivers, countries/regions, and their contributions to the field's development have received little attention. As a result, it is critical to monitor technological advances in hydrogen energy production and investigate the key enablers of these advancements. Against this backdrop, the current study employs patent analysis tools to achieve four primary goals: (1) to track the development trends in the field of hydrogen production from 2000 to 2019; (2) to identify and compare the recent development trends in the last five years according to the feedstock, i.e., fossil fuel, water, and biomass-based technologies; (3) to predict the technology life cycle of the two main groups of hydrogen production technologies (fossil and renewable); (4) to identify and compare the key drivers of hydrogen production technologies from a statistical standpoint. The findings of the study may aid in identifying technical prospects in the field of fossil and renewable-based hydrogen production, and decision-makers may use them as a reference in developing a strategic plan for future technological growth. • Patent review on hydrogen production technologies from 2000 to 2019. • Japan, US, China are the leading countries in the field. • Recent developments are focused on renewable energy-based technologies especially water. • Technology maturity rate of renewable-based technologies is about 57%. • R&D expenditure strongly promotes hydrogen production innovations. [ABSTRACT FROM AUTHOR]

This paper examines to what extent a rise in inflation expectations stimulates current household expenditure in Japan. Using matched household datasets, we find the following. First, to the extent that the rise in inflation expectations is from about 0% to the 2−10% range, durable goods expenditure is significantly stimulated. Second, total expenditure increases by 1.0% in response to a one percentage point rise in inflation expectations, about 82% of which is explained by the response of durable goods expenditure. Third, storable and non-storable non-durable goods expenditures (especially the latter) do not respond significantly to the inflation expectations. Finally, a temporary rise in inflation expectations immediately stimulates total expenditure, but produces a similar degree of decline over a few quarters, with virtually no long-run impact. [ABSTRACT FROM AUTHOR]

The purpose of this paper is to study the birth of space age and the distinguished achievements in the space-age painting aesthetics inspired by space exploration. It has been 66 years ever since the first successfully launch of the artificial satellite Sputnik 1 on October 4, 1957, generally recognized as the first year of space age. Exemplified by the best and most well-known "NASA Art Program", many major space agencies have sponsored the art program. In Japan, the Japanese Aerospace Exploration Agency (JAXA) supports the art program through its Public Affairs Department. In the European Space Agency (ESA), one of its well-known residence artists is Aoife van Linden Tol. For 66 years of the space age, there are many outstanding painters with many distinguished achievements and heritage of aesthetic paintings created. In particular, Robert Rauschenberg's work " Buffalo II " painted in 1964 has become a classic masterpiece that realized the price of $ 88 million at Christie's auction in 2019. • It has been 65 years since the launch of Sputnik 1 in 1957 generally recognized as the first year of space age. • After the well-known "NASA Art Program", many major space agencies have sponsored the art program. • In Japan, the Japanese Aerospace Exploration Agency (JAXA) supports the art program through its Public Affairs Department. • In the European Space Agency (ESA), one of its well-known residence artists is Aoife van Linden Tol. • Robert Rauschenberg's work " Buffalo II " painted in 1964 priced $88 million at Christie's auction in 2019. [ABSTRACT FROM AUTHOR]

Presents several papers published in the 2005 issue of the journals "Journal of the Society of Powder Technology, Japan" and "Powder Science & Engineering." "Effect and Behavior of Liquid Additive Molecules in Dry Ultrafine Grinding of Limestone," by M. Hasegawa et al; "Characteristics and Hydrogen Desorption Property of Nanostructured Graphite Produced by Grinding in Vacuum Atmospheres," by M. Shirahige et al; "Powder Technology and Electrostatics," by Y. Murata.

Presents a bibliography of original research papers about powder process industry already published in Japanese journals including the "Journal of the Society of Powder Technology" and the "Powder Science & Engineering." "Study on Influential Factor in Hardening Phenomena of Coal Ash Bed," K. Higashiyama, H. Kanda, H. Shirai, H. Makino and R. Kurose; "Influence of Humidity on Binderless Granulation in a Spouted Bed," by S. Hatano, K. Kaneko, Y. Oura and S. Mori; "Formation and Reduction of Dioxin," by M. Takeuchi; "Trend of Chemical Accidents," by M. Wakakura.

With tidal energy demonstration projects with one or a small number of turbines having provided very positive results, the technology is moving to the commissioning and operation of tidal energy farms. For this next step, the understanding of the wakes generated downstream of the turbines is crucial to optimize the array performance. To date, the analysis of wakes of MW-scale tidal turbines has been made by numerical methods or experimentally with downscaled rotors. However, no consensus on a methodology to characterize wakes generated by full-scale turbines based on data measured on-site has yet been reached. The present paper introduces a new method to compare current velocity data measured before and during turbine operation that minimizes the impact of the spatial and temporal variability of tidal currents, thus enabling the estimation of the velocity deficit caused downstream of the turbine. Through this method, a characterization of the near wake was possible, with velocity deficits of 0.537, 0.463, 0.469 and 0.431 at 2D, 3D, 4D and 5D from the turbine. Results from this paper present a very valuable tool for the validation of numerical models aiming to estimate the wake losses in tidal energy farms. • Wake from a 0.5 MW bottom-fixed tidal turbine in a tidal site is characterized. • A new method to calculate velocity deficit with vessel-mounted ADCP data is presented. • Velocity deficit at the rotor hub height decreases from the turbine to a 5D distance. • Farther from 5D, the turbine impact on current velocity dissipates. [ABSTRACT FROM AUTHOR]

Gene editing (GnEd) involves using a site-directed nuclease to introduce a double-strand break (DSB) at a targeted location in the genome. A literature search was performed on the use of GnEd in animals for agricultural applications. Data was extracted from 212 peer-reviewed articles that described the production of at least one living animal employing GnEd technologies for agricultural purposes. The most common GnEd system reported was CRISPR/Cas9, and the most frequent type of edit was the unguided insertion or deletion resulting from the repair of the targeted DSB leading to a knock-out (KO) mutation. Animal groups included in the reviewed papers were ruminants (cattle, sheep, goats, n =63); monogastrics (pigs and rabbits, n =60); avian (chicken, duck, quail, n =17); aquatic (many species, n =65), and insects (honeybee, silkworm, n =7). Yield (32%), followed by reproduction (21%) and disease resistance (17%) were the most commonly targeted traits. Over half of the reviewed papers had Chinese first-authorship. Several countries, including Argentina, Australia, Brazil, Colombia and Japan, have adopted a regulatory policy that considers KO mutations introduced following GnEd DSB repair as akin to natural genetic variation, and therefore treat these GnEd animals analogously to those produced using conventional breeding. This approach has resulted in a non-GMO determination for a small number of GnEd food animal applications, including three species of GnEd KO fast-growing fish, (red sea bream, olive flounder and tiger pufferfish in Japan), KO fish and cattle in Argentina and Brazil, and porcine reproductive and respiratory syndrome (PRRS) virus disease-resistant KO pigs in Colombia. • Gene editing (GnEd) can introduce useful genetic alterations in food animals • A total of 212 papers using GnEd in animals for agriculture were identified • Yield, reproduction, and disease resistance were the most commonly targeted traits • CRISPR/Cas9 was by far the most prevalent GnEd system used to edit animal genomes • Three species of GnEd fast-growing finfish have already been commercialized in Japan [ABSTRACT FROM AUTHOR]

In this paper, the authors present a two-step model to obtain quasi-optimal solutions for the storage and transportation of renewable energy as its installation becomes more widespread in remote areas. The model is formulated as a total cost minimization linear programming problem and considers both renewable energy facilities and the energy supply and demand of the entire country. The first step of the model optimizes the entire country, while the second step determines the marginal capacity of energy storage and transportation facilities when the excess production capacity of remote renewable energy is added. This approximation for reducing computational complexity is shown to be sufficiently accurate under realistic conditions. The authors apply the model to analyze energy storage and hydrogen production at renewable energy power plants in Japan in 2050. The study shows that photovoltaic power generation uses storage batteries attached to the power plant for electricity transmission. In contrast, wind power generation transmits most electricity directly without storage batteries and converts some into hydrogen for consumers. The proposed lightweight model allows for numeral sensitivity analyses, which provide valuable insight into optimizing energy storage and transport of renewable energy. • We developed a 2-step model for quasi-optimization of equipment at VRE site. • This model optimizes energy storage and transport with VRE deployment. • If additional VRE is sufficiently small, the model division retains sufficient accuracy. • Energy supply costs minimized by combining power transmission and H 2 transportation. • PV has large LIB, while WT has direct transmission and H 2 production. [ABSTRACT FROM AUTHOR]

Aspirations for the future can influence investments made today, and gender gaps in aspirations can perpetuate gender gaps in outcomes. In this paper, we explore how the local labor market affects gender gaps in aspirations. Using a national longitudinal survey from Japan, we begin by documenting large gender differences in adolescents' aspirations with respect to education, marriage, and fertility, as well as parental aspirations for their child's education. We then show that these gender gaps – specifically, boys aiming for higher educational attainment as well as later marriage and fertility – are significantly smaller in municipalities with higher female employment. Consistent with this, we also find that female employment is associated with higher parental investments in girls relative to boys. We detect similar patterns when examining realized outcomes at age 19. [ABSTRACT FROM AUTHOR]

The present study demonstrates how the environmentally weighted material consumption (EMC) indicator can be used to assess the resource efficiency of bioeconomy policies by calculating thirteen categories of environmental impacts associated with the production and the use of 146 biomass resources in Japan. The total environmental impact, expressed in the Japanese life cycle database in Japanese yen (JPY), decreased from 2,444 × 109 JPY in 1990 to 1,870 × 109 JPY in 2010. Supply chain related emissions (upstream) represented more than 98% of the impacts for all years. Land use, resource consumption, global warming, and urban air pollution were the main impact categories accounting respectively for 45%, 32%, 14% and 8% of the impacts. Ten products were found responsible for more than half of the impacts: rice, raw milk, beef cattle, painted printing paper, broiler, rolls of newsprint, hen egg, squares, common plywood and lumbers. Improvement of the production processes, reduction of consumed amounts and dietary change were identified as potential strategies for reducing the environmental impacts of these materials. Still, finding the best policy option may require the development of a life cycle assessment database able to differentiate organic and conventional agriculture and to better represent the production and environmental specificities of importing countries. • Environmentally weighted material consumption as an indicator of bioeconomy. • Detailed analysis of 146 biomass materials' environmental impacts. • Land use and resource consumption are the main impact categories. • Ten products are responsible for 50% of the total impacts. • Yield increase, diet shift, and paper recycling can reduce biomass related impacts. [ABSTRACT FROM AUTHOR]

• This paper aims to explain the role of GEE in seismic anomalies detection. • Two recent powerful earthquakes in Japan (13 February and 20 March 2021) were discussed. • Time series of AOT, Chlorophyll and Ozone precursors deduced from GEE platform. • They were investigated using Median and LSTM methods. • Our satisfactory results show that we will see a significant leap forward in studies of earthquake precursors. Nowadays, satellite data is an appropriate and undeniable source for studying earthquake precursors due to their diversity, wide coverage, being up to date and low cost. Time series analysis of satellite data plays an important role in the process of detecting seismic anomalies in earthquake warning systems. But in order to reduce uncertainty during the seismic anomalies detection, it is necessary the use a variety of satellite data, although it leads to increase of data size and processing time. This paper aims to explain the role of Google Earth Engine (GEE) cloud platform in considerable progress of seismo-Lithospheric Atmospheric Ionospheric (LAI) anomalies detection in earthquake early warning systems. Among the different studied earthquakes, for example two recent powerful earthquakes in Japan (13 February and 20 March 2021) have been discussed. Deduced time series of three precursors (i.e. Aerosol Optical Thickness (AOT), Chlorophyll and Ozone) from GEE platform were investigated using Median method and a Long Short-Term Memory (LSTM) neural network to detect potentially seismo-LAI anomalies. Our satisfactory results show that with the addition of other various satellite data and also known predictors intelligent algorithms such as deep learning to GEE platform, we will see a significant leap forward in studies of earthquake precursors. [ABSTRACT FROM AUTHOR]

• The mass campaign carried out by the emergency import of OPV in 1961 achieved great results for polio control in Japan. • School influenza vaccination in the 1960–80 s was discontinued without adequate and proper evaluation. • The judgment by the Tokyo High Court in 1992 and the discontinuation of the use of the MMR vaccine in 1993 were attributed for the creation of the so-called 'vaccine gap.' • In the revision of the Immunization Act in 1994, a big change was added to individual vaccination by 'obligation to make efforts.' • From around 2010, efforts have been made to bridge 'vaccine gap' and establish the global standard in vaccination. This paper reviews the administration related to vaccination in Japan after the enactment of the Immunization Act in 1948, under which vaccination was implemented mandatory for the public. To enhance the effectiveness of vaccination activities, the government implemented group vaccination, which is convenient for vaccinating recipients all at once. In 1976, Japan established the relief system for health damage after vaccination. While some projects, such as the mass administration of live oral polio vaccine in 1961, achieved excellent results, incidents leading to health damage occurred, such as the diphtheria toxoid immunization incident (1948) and frequent occurrence of aseptic meningitis owing to the measles, mumps, and rubella vaccine (1989). In December 1992, the Tokyo High Court sentenced that the onset of health damage after vaccination could be attributed to the negligence of the national government. In the revision of the Immunization Act in 1994, the "mandatory vaccination" enforced until then was changed to "recommended vaccination." The Act was also changed to recommend "individual vaccination" in principle, which is performed after primary care physicians investigate the physical condition of individual recipients and carefully conduct preliminary examination. For approximately 20 years from the 1990s, a vaccine gap existed between Japan and other countries. From around 2010, efforts have been made to bridge this gap and establish the global standard in vaccination. [ABSTRACT FROM AUTHOR]

Underground hydrogen storage (UHS) in depleted hydrocarbon reservoirs is a prospective choice to store enormous volumes of hydrogen (H 2). However, these subsurface formations must be able not only to store H 2 in an effective and secure manner, but also to produce the required volumes of H 2 upon demand. This paper first reviews the critical parameters to be considered for geological analysis and reservoir engineering evaluation of UHS. The formation depth, the interactions of rock-brine-H 2 , the caprock (seal) and well integrity are the most prominent parameters as far as UHS is concerned. In respect of these critical parameters, tentative H 2 storage is screened from the existing gas storage fields in the Niigata prefecture of Japan, and it was revealed that the Sekihara gas field is a suitable candidate for UHS with a storage capacity of 2.06 × 108 m3 and a depth of 1000 m. Then, a series of numerical simulations utilizing CMG software was conducted to find out the extent to which critical parameters alter H 2 storage capacity. The results demonstrated that this field, with a recovery factor of 82.7% in the sixth cycle of production is a prospective site for H 2 storage. [Display omitted] • Niigata prefecture in Japan has a good potential for underground H 2 storage. • Sekihara, Kumoide, and Katakai fields are the top candidates for storage of H 2. • A comprehensive review of crucial parameters for the underground H 2 storage is provided. • Effect of the crucial parameters studied using CMG software in the Sekihara field. • Reservoir simulation proved the feasibility of H 2 storage in the Sekihara field. [ABSTRACT FROM AUTHOR]

In recent years, there has been renewed interest in diversifying the understanding and discussion about the causes of depression to move beyond biomedical determinism—a view that biomedical factors are the ultimate cause of an individual's depression. There is increasing emphasis on diversity in how people seek to articulate the causes of depression to incorporate non-biomedical dimensions. Furthermore, the biomedical understanding of depression has been increasingly questioned due especially to emerging limitations in pharmacotherapy. These shifts encourage social analyses that explore what narratives as to the causes of depression are constructed and presented with relative plausibility in different contexts and why and how. By analysing published memoirs of individuals diagnosed with depression in Japan, this study aims to provide fresh insights into narratives around the causes of depression. It illustrates how memoirs portray depression and its perceived causes in characteristic ways in a nation that adopts Western diagnostic systems, biomedical therapeutics and other relevant technologies. I will show that 'burnout' is the dominant theme in the Japanese data, diverging from the predominantly biomedical narrative in Western societies. This burnout narrative depicts depression as the somewhat unfortunate but unsurprising result of overwork arising from individual active adaptations to structural features of the Japanese work culture. I argue that reasons, rather than causes, articulate the making of the burnout narrative by revealing the interplay between the structural and individual and ultimately enrich the understanding of depression. The paper concludes with a call for exploring the shifting relationship between illness and normalcy that the burnout narrative implies. I suggest that further studies could explore how the boundaries between normalcy and illness are enacted and re-enacted and to what avail through public discourse and through shifting diagnostic schemata in the context of different national norms and practices. • There are international differences in how depression is experienced and represented. • Biomedical explanations of depression are frequently documented in the literature. • This paper shows ways in which depression is explained in the language of burnout. • Burnout emphasises the interaction between the individual and the structural. • Distinguishing reasons from causes helps better understand burnout and depression. [ABSTRACT FROM AUTHOR]

This paper examines the conflicts and challenges faced by women managers in Japan following the introduction of a new law in 2020 which merely obliges employers to take preventive measures against workplace bullying and pawahara (power harassment), but does not stipulate any criminal punishment for corporations or individuals responsible for workplace harassment, or the specific grounds for victims to have the right to claim damages. Cases are left to be disputed and decided in a costly and complicated process of arbitration, which could further exacerbate the precarious position of vulnerable workers, including women managers who are not only a small minority, but many are also marginal players in the workplace where job promotions do not enhance their participation in corporate decision-making. This paper elucidates how the new law ironically enables employers to legitimize discriminatory practices and acts of harassment against women, with serious, long-term ramifications on the emotional and mental health of these workers, as well as on the gendered workforce in Japan amidst global trends towards improving gender equality. [ABSTRACT FROM AUTHOR]

The shear wave velocity is among the key parameters that are responsible for damage caused during an earthquake. Determining shear wave velocity is a costly and time-consuming direct geophysical method. In the present paper, a machine learning model has been developed to obtain the subsurface shear wave velocity profile without using direct methods. The bore log information and the subsurface shear wave velocity profile available at various stations of Japan's Kyoshin network (K-NET) have been utilized for training this machine learning model. The parametric correlation study indicates that simple parameters like rock/soil type, the thickness of the layer in the model, and standard penetration test (SPT-N) value directly correlate with the medium's shear wave velocity. A stacked ensemble machine learning model named VelProfES (an acronym for Velocity Profiler using Ensemble machine learning models) has been developed in this paper and has been utilized for effective prediction of the shear wave velocity profile using basic information from borelog data. The dataset used in the training and testing of the machine learning model consists of borelog and shear wave velocity information from 1101 stations. Of 1101 stations, 657, 283, and 71 stations have been utilized for training, testing, and validating the machine learning model. Training, testing, and validation of the developed machine learning model consist of parameters from 12351, 5279, and 1388 velocity layers. The problem of data imbalance based on soil type has been addressed using an additional 10510 layers of synthetic borelog data generated from conditional generative adversarial networks (CTGANs). A feature and model ablation study was conducted for the VelProfES model to provide substantiation for the model and feature selection choices. The predicted shear wave velocity profiles were compared at specific stations, focusing on average velocities at 5, 10, 15, and 20 depths. Further, the predicted values have been compared with the empirical relation of Sil and Haloi (2017) and a trained polynomial model. The machine learning model demonstrates close alignment between predicted and actual values across a broad spectrum of velocities, a contrast not observed in the empirical relation and polynomial model. The results show that the machine learning models and augmented data generated using CTGANs can efficiently minimize the error between actual and predicted subsurface shear wave velocity values. • Describe detailed machine learning strategy for predicting shear wave velocity. • Generative Adversarial Network used to handle unbalanced data problem. • Describes correlation of shear wave velocity with Rock/soil type, layer, and SPT-N. • Comparison of described model with recently developed methods for all regions. • Performance of the machine learning model is predicted. [ABSTRACT FROM AUTHOR]

Pollen productivity estimate (PPE) is one of the parameters necessary for pollen-based quantitative reconstruction of vegetation in the past. This paper summarizes and reviews the absolute PPEs (aPPEs) that were obtained with the area-based flower counting approach since the 1970s. The data for 23 species of trees are available from Japan and for 22 species of Poaceae from Japan, Spain, and Morocco. The aPPE values vary from 1 to 60 [1012 grains·ha−1·year−1], and are comparable to those previously reported in Europe and using different methods and approaches. The mean aPPEs of temperate conifers, such as Sciadopitys verticillata , Cryptomeria japonica , and Chamaecyparis obtusa , are as high as those of some of the common broadleaved trees, Castanea mollissima , Castanopsis cuspidata , and Alnus spp. The mean aPPEs of Abies firma , Fagus crenata , and Betula platyphylla are low, and those of Pinus densiflora , Quercus spp., Juglans ailanthifolia , Carpinus tchonoskii , Aesculus turbinata , and Poaceae spp. are intermediate. The relative PPE (rPPE) values of the arboreal taxa (relative to Poaceae), calculated using the aPPEs presented here, are smaller than those obtained in Western Europe and China based on the Extended R-value model approach. Differences in the sampling and analytical methods, as well as the interregional differences in Poaceae pollen productivity, might have contributed to the discrepancies observed. Although further studies are necessary, the flower counting approach is practical and informative for species-specific estimates of absolute pollen productivity and provides critical parameters for quantitatively reconstructing past vegetation in absolute units using the rates of pollen accumulation in sediments. [ABSTRACT FROM AUTHOR]

Thoracic ossification of the posterior longitudinal ligament (TOPLL) is a rare but intractable disease, and is the second leading cause of thoracic myelopathy. This study aimed to illustrate the overall knowledge structure and development trends of TOPLL, using a bibliometric analysis and newly developed visualization tools. Research data sets were acquired from the Web of Science. The literature search was also limited to articles that were published until October 30, 2021. VOS viewer and Citespace software was provided to analyze the data and generate visualization knowledge maps. Annual trend of publications, distribution, H-Index status, co-authorship status, and research hotspots were analyzed. A total of 206 publications met the requirement. Japan published most papers (92), both total citations (1574) and H-index (24) ranked first of all the countries. The most productive organization was Peking University (22). The most productive author was Yamazaki M (18). The most productive journal was Spine (33). Diagnosis and treatment on the accuracy of surgical segments, prognosis of patients, and gene research were the research hotspots in the recent years. The study showed an upward trend with a stable rise in recent years. Japan is country with the highest productivity, not only in quality, but also in quantity. Peking University and Spine have been the largest contributors. Indeed, this study provides great insights to the growth and development of TOPLL. Moreover, it will contribute to the growth of the international frontier. [ABSTRACT FROM AUTHOR]

The High Fluence Irradiation Facility at the University of Tokyo, which had provided a platform for dual-beam irradiation in Japan, was severely damaged by the 2011 earthquake. This paper reports a modification at this facility, i.e., installing a low-energy ion implanter instead of repairing the previous Van de Graaff accelerator. The platform of the dual-beam irradiation and/or s gas-ion beam irradiation was reconstructed, and the newly installed ion implanter was a stable, uniform, and high-density light element ion beam. The radiation-induced amorphization (RIA) behavior in Zr(Fe,Cr) 2 Laves phase was investigated in 180 keV-He+ beam irradiation to assess the performance of this ion implanter, and the irradiation temperature and dose-dependent RIA behavior were confirmed. Implying that this modification ensures the capability in terms of gas-ion beam irradiation and dual-beam irradiation in this facility, which will promote the research progress on radiation effects in nuclear material. [ABSTRACT FROM AUTHOR]

• Wrong-way driving involved errors in either recognition or judgement. • Errors in the recognition involved overlooking no-entry signs on a highway. • Errors in judgement involved turning right despite seeing no-entry signs. • Wrong-way driving in older people related to impairments in executive function. About 200 highway wrong-way driving cases occur annually in Japan, of which about 70% are caused by older drivers. The number of these cases has remained consistent despite adoption of full-fledged measures against wrong-way driving, thus demonstrating the need for further measures. Reports indicate that older drivers include those with cognitive decline. Moreover, it has been revealed that drivers over 75 years of age who caused wrong-way driving had lower test scores in the usual cognitive function tests performed at the time of licence renewal. However, there is no clear evidence on the relationship between cognitive decline and driving behaviour that stimulates wrong-way driving. In this paper, we reproduced a wrong-way driving approaching a right turn to an expressway exit in a virtual environment using a driving simulator for older drivers, including those with mild cognitive impairment (MCI). In addition to the measurement of driving behaviour and eye-tracking during simulator driving, we conducted a cognitive function test to investigate the relationship between driving behaviour and visual behaviour factors that initiate reverse running and cognitive decline. The results revealed that the reason for the start of a highway wrong-way driving may be a human error at the recognition stage of overlooking a visual wrong-way driving countermeasure, or a human error at the judgement stage of failing to suppress action despite noticing the visual countermeasure. Additionally, attentional and executive functions were related to the wrong-way initiative, although MCI did not affect it. This suggests that those who could not control their wrong-way driving behaviour despite observing the signs had specific executive function deficits. [ABSTRACT FROM AUTHOR]

This paper examines the effects of HSR development on airport technical efficiency and the labor productivity at airports. Existing literature mainly focuses on the impacts of HSR on passenger traffic. In addition to passengers, HSR development may influence airports' other outputs such as cargo and flight movements together with various inputs. These inputs and outputs collectively determine airports' technical efficiency. With access to a dataset consisting of 46 Chinese airports and 16 Japanese airports from 2007 to 2015, the paper firstly adopts both the standard two-stage Data Envelopment Analysis (DEA) and double bootstrap methods to evaluate the impacts of HSR development on airports' technical efficiency. We then evaluate the effects of HSR on airport labor productivity which is measured by both work-load units per employee and aircraft movements per employee. Our main findings indicate that HSR development relates to a decline in airport efficiency. Airports located in cities that have better connectivity or accessibility in the HSR network suffer more efficiency loss than the others. It is also observed that the locational advantage of HSR stations relative to airports is negatively associated with airport efficiency. By contrast, good intermodal linkage between the airport and its nearest HSR station is positively correlated with airport efficiency. Furthermore, the study reports different results between China and Japan with respect to the effects of HSR on labor productivity. [ABSTRACT FROM AUTHOR]

Mobile learning (m-learning) is gaining its importance in recent years. For libraries, it is inevitable to adapt to this trend and provide various information services and support for m-learning. This paper studies the m-learning usage of Library and Information Science (LIS) students, who will be the new blood for the library in future. In this paper, we invited 267 subjects from Hong Kong, Japan, and Taiwan to participate in our online survey. We found that LIS students from these regions do adopt communication tools and social media for m-learning. However, they less frequently use their smartphones for academic reading. Plus, they rely more on search engines for fulfilling their information needs instead of library resources. We also found that the lack of a mobile version of the library website constitutes a significant barrier in m-learning, but the lack of mobile apps is relatively acceptable by the respondents. The result of this study shows that there are no big differences in m-learning usage among the three regions, except that LIS students from Hong Kong are accessing the learning management platforms via their smartphones more frequently compared to students from Japan and Taiwan. [ABSTRACT FROM AUTHOR]

The use of robots is being widely considered to ensure the inheritance of calligraphy, which is a cultural art peculiar to China and Japan. Many researchers have attempted to generate motion command values to allow robots to inherit calligrapher skills. In this paper, we constructed a model that generates motion command values considering time-series positions and forces from human motion data and character images. However, since it is difficult to acquire a large amount of motion data due to physical restrictions, we compared the accuracy based on the number of training data. The performance of the model was evaluated with motion data generated using the image data for evaluation. We also showed that calligraphy is a delicate task and that using force data can improve results. • This research proposes a deep-learning-based skill transfer of a calligrapher. • The proposed model generates motion command from human motion data and images. • The accuracy based on the number of training data is compared and analyzed. • The performance was evaluated with motion data using the image data for evaluation. [ABSTRACT FROM AUTHOR]

The 4th Asia Partnership Conference of Regenerative Medicine (APACRM) was held online on April 15, 2021, to promote regulatory harmonization of regenerative medicine products throughout Asia. Recognizing domestic regulatory guidelines within each country and region, and their underpinning rationales, is an important initial step toward a convergence of regulations. The 4th APACRM consisted of an open dialog with regulatory agencies regarding nonclinical and quality settings for cell therapy products (CTPs) through industry presentations and panel discussions with regulatory agencies. The latest updates on regenerative medicine fields in each country and region, and specific regulatory schematics in Japan, were also introduced. The objective of this paper is to summarize the proceedings of the 4th APACRM for public dissemination and to foster further discussion in the future. [ABSTRACT FROM AUTHOR]

This study presents Sr-isotope data to determine the stage affiliation of different parts of the Miocene Sertunaiskaya and Kurasiyskaya formations in Sakhalin, as well as the upper part of the Togeshita Formation in Hokkaido. Additionally, it confirms a diachronous boundary between the Sertunaiskaya and Kurasiyskaya formations. The data received will be useful for globally correlating the Miocene formations of the Sakhalin-Hokkaido area. The study indicates that the Japan and Kuril back-arc basins in the Western Pacific underwent their final opening stages during the Middle Miocene (18.1–17.7 and 15.9–14.2 Ma, respectively), as determined by the SIS method. This process was likely influenced by both global and local factors. One of the local influences on the formation of back-arc basins in the Western Pacific appears to be the influx of cool boreal waters, as indicated by the δ18O signals. The Miocene data from the Sakhalin-Hokkaido area, including evidence from Sr, O, and C isotopes, combined with corresponding paleontological, stratigraphic, palaeomagnetic, and palaeobiogeographic data from the Paleogene and Neogene, provide a four-stage chronological sequence of events related to the opening of the Western Pacific's back-arc seas. This paper presents original information on the Miocene C-isotope excursion in the Western Pacific, which are correlated with the Monterey Event. Recent data on this topic may have enhanced our comprehension of the conditions required for the formation of hydrocarbons, which are found in substantial amounts in the Miocene of northern Sakhalin and Hokkaido. • The SIS method enables the identification of the stage affiliation of Miocene formations in Sakhalin and Hokkaido. • Miocene molluscs were analysed for O- and Sr-isotopes to differentiate temperature changes caused by local and global influences. • The Japan back-arc basin may have begun to form in the late Ypresian of the Eocene. • O-isotope analyses indicate that cool boreal waters entered the Japan basin around 18–17 Ma and the Kuril Basin around 15–14 Ma, which may correspond to their eventual opening. [ABSTRACT FROM AUTHOR]

• An LRFD framework for embankments considering climate change effects is established. • Additional partial factors are introduced to account for the climate change effects. • Non-stationary maximum flood depth is developed using a peak-over-threshold method. • Embankment reliability is evaluated against overtopping and slope failure. • The proposed framework can serve as a reference for future code design. Riverine floods have become increasingly prevalent on a global scale, posing significant risks to infrastructure systems and communities. The escalating impacts of climate change associated with the increase in rainfall intensities and frequencies necessitate the improvement of the existing design methodologies to account for the non-stationary climate change effects to ensure that the reliability is above the target level and mitigate future flood disasters. This paper presents a novel LRFD approach for river embankments subjected to extreme rainfall under non-stationary climate change effects. This approach introduces an additional partial factor to account for the effects of climate change. Precipitation and temperature projections are collected from various climate models considering several cases of emission scenarios. An integrated hydrological and hydraulic modeling of the analyzed river is carried out to estimate the associated time-variant river discharge and water surface elevation. The non-stationary extreme value associated with the maximum flood level is leveraged using the peak-over-threshold approach. The embankment reliability and the corresponding most probable points are evaluated using limit states associated with overtopping and slope failures. Based on the estimated and target reliability indexes, the design point for each random variable is assessed considering the cases with and without climate change effects. Finally, the partial factors associated with climate change effects are determined. As an illustrative example, the proposed framework is applied to the Ashida River in Fukuyama city of Japan. [ABSTRACT FROM AUTHOR]

Streamlining urban areas to appropriate sizes based on the current population structure is an important and urgent issue. Therefore, Japan enacted the Location Normalization Plan in 2014, and a shift toward a more compact regional structure is underway. However, this plan cannot force people to migrate to the target area. Consequently, the formation of a compact regional structure is expected to persist for several decades. It consequently is crucial to shortly convert to a compact regional structure based on the voluntary migration of residents before the living environment outside residential zones deteriorates. This study analyzed the time required for the population to reach zero in urbanization-promoting areas excluded from residential attraction, using spatial statistical analysis. We assumed that multiple generations were the targets of the migration promotion policy, and considered the differences in each scenario. The results demonstrate that >100 years would be required before the natural withdrawal of target areas, and that migration policies targeting pre- and post-retirement generations were the most effective. This paper's contribution is valuable in that it discusses the importance of promoting relocation based on the viewpoint of the shortest possible shrinkage to the compacting measures currently being undertaken worldwide in matured cities. • Targets of the migration promotion policy • Importance of promoting relocation based on the shortest possible shrinkage • Policies appropriate for specific time periods and age groups should be implemented. • Migration policies targeting pre- and post-retirement generations [ABSTRACT FROM AUTHOR]

• RF conditioning of RFQ of IFMIF/EVEDA accelerator (LIPAc) reached stable CW at 80 % of nominal voltage at the end of 2021. • Conditioning towards nominal voltage at CW was stopped in March 2022 because of vacuum leak from one of the O-Ring of the RF windows, damaged by high temperature. • Several coupled RF and thermal simulations of the couplers of the RFQ were performed with FEM codes. Thermal weak point was identified in the contact between the anchor of the RF window and the cooled inner conductor of the coupler. • A solution to improve cooling of the RF window that could be implemented quickly with minor modifications of the RF windows parts of the couplers was found. • After the testing and validation of the modification in a prototype, the couplers with the modified parts were successfully installed in RFQ and RF conditioning of RFQ resumed in June 2023. Under the Broader Approach (BA) agreement, the Accelerator Facility validation activities aim at demonstrating the acceleration of 125 mA D+ beam up to 9 MeV. This is the main goal of the Linear IFMIF Prototype Accelerator (LIPAc) under installation and commissioning in Rokkasho, Japan [ 1 , 2 ]. The LIPAc commissioning by accelerating the beam through the entire line is currently on-going at Rokkasho Fusion Institute [ 3,4 ]. Other than the beam commissioning, in 2021 and 2022 extensive conditioning experimental campaigns have been carried out on the Radio Frequency Power System (RFPS)-RFQ system to reach CW [5]. The RFPS-RFQ is composed of 8 RF-RFQ tetrode based chains injecting RF power into the RFQ by 8 couplers. The target of the RFQ conditioning campaigns is to reach CW operation at nominal vane-voltage of 132 kV. RFQ could achieve CW field of 105 kV at the end of 2021 [ 5,8 ]. During the RFQ conditioning campaigns in 2022, the conditioning was stopped because of abnormal increase of vacuum pressure due to a leak from one O-Ring of the couplers. The 8 couplers are equipped with a ceramic window (vacuum barrier) using O-ring for sealing purposes [ 9 ]. Extensive simulation and design studies have been carried out and an upgraded design of the parts near the RF window of RFQ coupler has been proposed and validated for implementation. This paper will focus on the RFQ couplers technical issue, analysis of the design upgrade, implementation of the upgraded solution and perspective for future improvements of the RFQ couplers designs in view of FNS and DONES application. [ABSTRACT FROM AUTHOR]

The Belle II experiment at KEK in Japan considers an upgrade for the vertex detector system in line with the accelerator upgrade for higher luminosity at long shutdown 2 planned for 2028. One proposal for the upgrade of the vertex detector called VTX aims to improve background robustness and reduce occupancy using small and fast pixels. VTX accommodates the OBELIX depleted monolithic active CMOS pixel sensor (DMAPS) on all five proposed layers. OBELIX is specifically developed for the VTX application and based on the TJ-Monopix2 chip initially developed to meet the requirements of the outer layers of the ATLAS inner tracker (ITk). This paper will review recent tests of the TJ-Monopix2 chip as well as various design aspects of the OBELIX-1 chip currently under development. [ABSTRACT FROM AUTHOR]

This paper presents comprehensive parametric analyses on the behavior of damage-repaired steel-concrete composite girders using CFRP sheets. Cross-sectional loss was considered on the lower steel flange at midspan to replicate corrosion damage in the girder. Damage was repaired using CFRP sheets to the underside of the lower flange. Non-linear Finite Element (FE) analyses were conducted on the repaired and intact composite girders. The FE models were validated using experimental results and a parametric study was carried out considering the variables such as number of CFRP sheets, CFRP elastic modulus, damage amount, epoxy resin elastic modulus, concrete strength, flange strength, and CFRP bonding area. The effect of parameters on failure components was studied for Limit States 1, 2, and 3 defined in the revised Design Specification for Highway Bridges in Japan (JSHB) (2017). Limit States 1 and 3 correspond to the service limit and ultimate Limit States in AASHTO, respectively. However, Limit State 2 is JSHB unique Limit State located between 1 and 3 in terms of functionality. Regression models were proposed to determine the load-carrying capacity of the repaired composite girder for 3 Limit States. Comparison between the proposed equation and FE-predicted values showed good agreement with prediction errors of ±10% to ±19%. The study showed that to restore the stiffness and load capacities for Limit State 1 high-modulus CFRP sheets and resins are more suitable options than the low-modulus sheets and resins. Finally, the study proposes the optimal repair method for damaged composite girder considering the Limit States. • Parametric analyses of damage repaired steel-concrete composite girder were conducted using CFRP sheets. • Effect of various parameters has been investigated. • Equations for loadcapacities of repaired composite girders for Limit States 1, 2 and 3 have been proposed. [ABSTRACT FROM AUTHOR]

Because transport in the port hinterlands heavily depends on roads with negative externalities, much social interest has been in modal shifts (MSs) to rail and shipping with lower environmental impact. Currently, leading industry sectors to ambitiously embrace technological innovations to decarbonize—consequently, in line with these changes, the significance of MSs should change; however, no previous studies have comprehensively presented the overall CO 2 emissions and transport mode shares for future regional cargo transport. This paper presents a scenario analysis of CO 2 emission reductions in the Japanese domestic hinterland of international maritime container transport based on future scenarios of technological innovation and change in shipper behavior. The simulation results using the global logistics intermodal network simulation model showed that up to 87% CO 2 reduction is possible, and the primary driver for this is technological innovation. Moreover, the significance of MSs fluctuates depending on the advancement of technological innovation, suggesting that MSs hold a degree of import as a decarbonization measure during the transitional phase toward carbon neutrality (CN) as technological innovation advances. The results of this study, which fluctuated considerably by scenario and timing, have policy implications with respect to the path to be followed toward CN, including whether to promote MSs. • Scenario analysis of CO 2 emission reductions in Japanese maritime transportation. • Up to 87% CO 2 reduction possible using technological innovation. • Significance of modal shifts fluctuated with the degree of technological innovation. • Policy implications suggesting that the path toward carbon neutrality is crucial. [ABSTRACT FROM AUTHOR]

[Display omitted] • Working team in JPMA made a consideration for implementing MCS for oral solid dosage forms. • It was prepared based on surveys of pharmaceutical companies in Japan, EU and the US. • It helps systemic approach for selecting manufacturing method based on API properties. The Manufacturing Classification System (MCS) classifies oral solid dosage forms according to the properties of the active pharmaceutical ingredient (API) to improve the selection of appropriate manufacturing methods. The concept of MCS was proposed by a group of European and American pharmaceutical scientists as part of the MCS Working Group. This topic has also generated interest in Japan, and the Japan Pharmaceutical Manufacturers Association (JPMA) considers it useful to investigate the actual status of manufacturing method selection in Japan with application of MCS framework. Since the manufacturing method and its selection are not in the public domain in Japan, the JPMA MCS project team conducted a survey in collaboration with the member companies. This paper summarizes the results of this survey and provides a proposal for the industrial environment in Japan while taking into account the results of the previous EU/US surveys. [ABSTRACT FROM AUTHOR]

Ongoing climate change has increased the impact of landslides and related slope disasters on infrastructure and human lives. Microwave satellite remote sensing, particularly interferometric analysis of synthetic aperture radar (InSAR) data, is a powerful tool for routine monitoring of the displacement of slopes on small wavelength scales, independently from solar illumination and cloud coverage. Although various sophisticated techniques for time-series InSAR have been developed, practical application in conjunction with geological analysis to reveal intrinsic and triggering factors of slope displacement is still limited. In this paper, we describe a practical case of time-series InSAR analysis with a special focus on its geological implications in northwestern Kyushu, a high-risk area for slope-related disasters in Japan. The extracted susceptible polygons from the InSAR results show accuracy comparable with that of other recent research on landslide mapping. Intrinsic factor analysis based on a geographic information system reveals that the displacement occurs on relatively gentle slopes instead of steep areas, corresponding to the transient zone of Paleogene-Neogene sedimentary rocks and basalt. Triggering factor analysis based on correlation coefficients reveals a significant link between some displacement areas with mean and/or maximum precipitation for each observation duration. Those findings confirm the importance of carefully accounting for the geological background for landslide susceptibility assessment and policy making, apart from topographic and meteorological conditions. [ABSTRACT FROM AUTHOR]

• The blanket testing facility for WCCB TBM was newly built in Rokkasho Fusion Institute, Japan. • An apparatus for flow accelerated corrosion testing under coolant condition of TBM was installed. • An apparatus for high heat flux testing under cooling with pressurized water using electron beam gun was installed. • An apparatus for ingress testing of pressurized water inside TBM was installed. • An apparatus for evaluating characteristics of beryllium-water reaction was installed. Intensive research and development activities have been conducted for designing a water-cooled ceramic breeder (WCCB) blanket system. In this system 325 °C/15.5 MPa of pressurized water removes heat injected and accumulated in blanket containers made of a reduced activation ferritic/martensitic steel, F82H. The container has lithium ceramics and beryllium pebbles as tritium breeder and neutron multiplier, respectively. In order to demonstrate performance of the system, especially for high-temperature pressurized water coolant, experimental apparatus have been installed in Rokkasho Fusion Institute, National Institutes for Quantum Science and Technology, Japan. These apparatuses enable to conduct the following experiment on full-scale mockups: 1) high heat flux (HHF) test to demonstrate heat removal of surface heat flux by electron beam gun simulating plasma, 2) flow assisted corrosion, 3) coolant ingress into dummy pebble beds, and 4) beryllium-water reaction between the coolant and the pebbles. In this paper, overviews, specifications, early results of these apparatus are reported. [ABSTRACT FROM AUTHOR]