34 results
Search Results
2. A feasibility study of composites produced from telephone directory paper, plastics, and other adhesives
- Author
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Steiner, P [Univ. of British Columbia, Vancouver, British Columbia (Canada)]
- Published
- 2020
3. Effect of moisture content on the accuracy and economic feasibility of oil–paper insulation prediction model.
- Author
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Li, Chong, Wu, Kai, and Cheng, Chuanhui
- Subjects
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PREDICTION models , *LIFE cycle costing , *MOISTURE , *FORECASTING , *FEASIBILITY studies , *HEAVY oil - Abstract
The condition assessment of oil–paper insulation is a vital issue in transformer management. To investigate the effect of moisture content on the accuracy of the prediction model, accelerated ageing experiments were performed with different initial moisture content (IMC) in laboratory condition. Two types of multi-parameter lifetime prediction models, e.g. with and without consideration of IMC, were presented for comparison purpose. The authors found that a better accuracy for its prediction results could be achieved by establishing the prediction models with the consideration of IMC. Besides, models considering IMC have better economic feasibility than that without considering IMC(non-IMC) as its total cost is cheaper according to life cycle cost (LCC) calculations. In addition, failure probability based on the proposed prediction models was also calculated as a direct indicator for evaluating the oil–paper insulation status. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
4. Spatial frequency domain imager based on a compact multiaperture camera: testing and feasibility for noninvasive burn severity assessment
- Author
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Anthony J. Durkin, Jun Tanida, Adrien Ponticorvo, Rebecca A. Rowland, Keiichiro Kagawa, and Gordon T. Kennedy
- Subjects
Paper ,Materials science ,genetic structures ,compound eye ,Multispectral image ,Biomedical Engineering ,Bioengineering ,Optical Physics ,Imaging phantom ,Phantoms ,law.invention ,Imaging ,Biomaterials ,Mice ,Optics ,Band-pass filter ,law ,Opthalmology and Optometry ,multispectral imaging ,Animals ,diffuse optics ,Skin ,CMOS sensor ,thin observational module by bound optics ,business.industry ,Phantoms, Imaging ,Optical Imaging ,Compound eye ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Rats ,Lens (optics) ,Wavelength ,burn wounds ,spatial frequency domain imaging ,Feasibility Studies ,Spatial frequency ,sense organs ,business ,Burns - Abstract
Significance: Spatial frequency domain imaging (SFDI) is a wide-field imaging technique that provides quantitative maps of tissue optical properties. We describe a compact SFDI imager that employs a multispectral compound-eye camera. This design enables simultaneous image acquisition at multiple wavelengths. Such a device has potential for application for quantitative evaluation of superficial tissues by nonspecialists in low-resource settings. Aim: The aim of this work was to develop a compact SFDI imager for widefield imaging of in-vivo tissue optical properties and verify its ability to measure optical properties of tissue-simulating phantoms and in a preclinical model of burn wounds. Approach: This compound-eye imager was constructed using a CMOS sensor subdivided into multiple regions, each having a bandpass filter and objective lens. The ability of the instrument to image optical properties was compared with (1) a commercial SFDI imager and (2) a laboratory-based system. Initial validation of ability to accurately characterize optical properties was performed using a tissue-simulating optical phantom. It was then applied to an established murine model of thermal contact burn severity. In-vivo measurements of the optical properties of rat skin were performed before and after the application of burns. Histology was used to verify burn severity. Results: Measurements of the tissue-simulating phantom optical properties made using the compound-eye imager agree with measurements made using the two comparison SFDI devices. For the murine burn model, the burns showed a decrease in the reduced scattering coefficient at all measurement wavelengths compared with preburn measurements at the same locations. This is consistent with previously reported changes in scattering that occur in full-thickness burns. Conclusion: We demonstrate the potential for SFDI to be translated into compact form factor using a compound-eye camera that is capable of obtaining multiple wavelengths channels simultaneously.
- Published
- 2021
5. Biomechanical pulping: A mill-scale evaluation
- Author
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Shipley, D
- Published
- 1999
6. Feasibility and effectiveness of electronic vs. paper partograph on improving birth outcomes
- Author
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Sumon Kumar Das, Tahmina Begum, Jelle Stekelenburg, Monjur Rahman, Sadika Akhter, Tarun Kanti Ghosh, Dewan Md Emdadul Hoque, Aminur Rahman, Iqbal Anwar, Parveen Fatima, Fatema Ashraf, and Public Health Research (PHR)
- Subjects
Maternal Health ,Social Sciences ,Logistic regression ,Pathology and Laboratory Medicine ,Prolonged labour ,Cultural Anthropology ,Geographical Locations ,Labor and Delivery ,0302 clinical medicine ,Obstetrics and gynaecology ,Sociology ,Pregnancy ,Medicine and Health Sciences ,Medicine ,030212 general & internal medicine ,Bangladesh ,030219 obstetrics & reproductive medicine ,Multidisciplinary ,Cross-Over Studies ,Labor, Obstetric ,Obstetrics ,Pregnancy Outcome ,Gestational age ,Obstetrics and Gynecology ,Institutional review board ,Hospitals ,Religion ,Obstetric Procedures ,Regression Analysis ,Female ,Research Article ,Adult ,Paper ,medicine.medical_specialty ,Asia ,Referral ,Science ,Surgical and Invasive Medical Procedures ,03 medical and health sciences ,Asphyxia ,Young Adult ,Signs and Symptoms ,Fetus ,Diagnostic Medicine ,Chi-square test ,Humans ,business.industry ,Cesarean Section ,medicine.disease ,Delivery, Obstetric ,Electronics, Medical ,Health Care ,Health Care Facilities ,Anthropology ,People and Places ,Birth ,Women's Health ,Feasibility Studies ,business - Abstract
BACKGROUND: The partograph has been endorsed by World Health Organization (WHO) since 1994 which presents an algorithm for assessing maternal and foetal conditions and labor progression. Monitoring labour with a partograph can reduce adverse pregnancy outcomes such as prolonged labor, emergency C-sections, birth asphyxia and stillbirths. However, partograph use is still very low, particularly in low and middle income countries (LMICs). In Bangladesh the reported partograph user rate varies from 1.4% to 33.0%. Recently, an electronic version of the partograph, with the provision of online data entry and user aid for emergency clinical support, has been tested successfully in different settings. With this proven evidence, we conducted and operations research to test the feasibility and effectiveness of implementing an e-partograph, for the first time, in 2 public hospitals in Bangladesh.METHODS: We followed a prospective crossover design. Two secondary level referral hospitals, Jessore and Kushtia District Hospital (DH) were the study sites. All pregnant women who delivered in the study hospitals were the study participants. All nurse-midwives working in the labor ward of study hospitals were trained on appropriate use of both types of partograph along with standard labour management guidelines. Collected quantitative data was analyzed using SPSS 23 statistical software. Discrete variables were expressed as percentages and presented as frequency distribution and cross tabulations. Chi square tests were employed to test the association between exposure and outcome variables. Potential confounding factors were adjusted using multivariate binary logistic regression methods. Ethical approval was obtained from the institutional review board of the International Centre for Diarrheal Disease Research, Bangladesh (icddr,b).FINDINGS: In total 2918 deliveries were conducted at Jessore DH and 2312 at Kushtia DH during one-year study period. Of them, 1012 (506 in each facility) deliveries were monitored using partograph (paper or electronic). The trends of facility based C-section rates was downwards in both the hospitals; 43% to 37% in Jessore and from 36% to 25% in Kushtia Hospital. There was a significant reduction of prolonged labour with e-partograph use. In Kushtia DH, the prolonged labour rate was 42% during phase 1 with the paper version which came down to 29% during phase-2 with the e-partograph use. The similar result was observed in Jessore DH where the prolonged labour rate reduced to 7% with paper partograph from the reported 30% prolonged labour with e-partograph. The e-partograph user rate was higher than the paper partograph during both phases (phase 1: 3.31, CI: 2.04-5.38, p < .001 and in phase 2: 15.20 CI: 6.36-36.33, p < .001) after adjusting for maternal age, parity, gestational age, religion, mother's education, husband's education, and fetal sex.CONCLUSION: The partograph user rate has significantly improved with the e- partograph and was associated with an overall reduction in cesarean births. Use of the e-partograph was also associated with reduced rates of prolonged labour. This study has added to the growing body of evidence on the positive impact of e-partograph use. We recommend implementing e-partograph intervention at scale in both public and private hospitals in Bangladesh.TRIAL REGISTRATION: ClinicalTrials.gov NCT03509103.
- Published
- 2019
7. Acceptability and satisfaction of project MOVE: A pragmatic feasibility trial aimed at increasing physical activity in female breast cancer survivors
- Author
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Kristin L. Campbell, Tanya Pullen, Joan L. Bottorff, Susan Ellard, Cristina M. Caperchione, Catherine M. Sabiston, Paul Sharp, Kayla Fitzpatrick, and Carolyn C. Gotay
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Gerontology ,Program evaluation ,Paper ,financial incentives ,health promotion ,Physical activity ,physical activity ,Experimental and Cognitive Psychology ,Breast Neoplasms ,microgrants ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Financial incentives ,Cancer Survivors ,Survivorship curve ,Surveys and Questionnaires ,medicine ,cancer ,Humans ,Oncology & Carcinogenesis ,030212 general & internal medicine ,Program Development ,Exercise ,Aged ,Motivation ,Focus Groups ,Middle Aged ,Patient Acceptance of Health Care ,medicine.disease ,Focus group ,Psychiatry and Mental health ,Health promotion ,Incentive ,Patient Satisfaction ,030220 oncology & carcinogenesis ,Papers ,oncology ,community‐based intervention ,Feasibility Studies ,Female ,women ,Psychology ,survivorship - Abstract
© 2018 The Authors. Psycho-Oncology Published by John Wiley & Sons Ltd. Objective: Despite the physical and psychological health benefits associated with physical activity (PA) for breast cancer (BC) survivors, up to 70% of female BC survivors are not meeting minimum recommended PA guidelines. The objective of this study was to evaluate acceptability and satisfaction with Project MOVE, an innovative approach to increase PA among BC survivors through the combination of microgrants and financial incentives. Methods: A mixed-methods design was used. Participants were BC survivors and support individuals with a mean age of 58.5 years. At 6-month follow-up, participants completed a program evaluation questionnaire (n = 72) and participated in focus groups (n = 52) to explore their experience with Project MOVE. Results: Participants reported that they were satisfied with Project MOVE (86.6%) and that the program was appropriate for BC survivors (96.3%). Four main themes emerged from focus groups: (1) acceptability and satisfaction of Project MOVE, detailing the value of the model in developing tailored group-base PA programs; (2) the importance of Project MOVE leaders, highlighting the value of a leader that was organized and a good communicator; (3) breaking down barriers with Project MOVE, describing how the program helped to address common BC related barriers; and (4) motivation to MOVE, outlining how the microgrants enabled survivors to be active, while the financial incentive motivated them to increase and maintain their PA. Conclusion: The findings provide support for the acceptability of Project MOVE as a strategy for increasing PA among BC survivors.
- Published
- 2018
8. Electricity generation from digitally printed cyanobacteria
- Author
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Marin Sawa, Andrea Fantuzzi, Paolo Bombelli, Christopher J. Howe, Klaus Hellgardt, Peter J. Nixon, Engineering & Physical Science Research Council (EPSRC), Howe, Christopher [0000-0002-6975-8640], and Apollo - University of Cambridge Repository
- Subjects
DEVICES ,Bioelectric Energy Sources ,Science ,Cyanobacteria ,Article ,ENERGY ,ALGAE ,Electricity ,BIOSENSOR ,Photosynthesis ,lcsh:Science ,Science & Technology ,Nanotubes, Carbon ,Synechocystis ,Equipment Design ,BIOELECTRICITY ,ARRAYS ,Multidisciplinary Sciences ,PAPER ,PATTERNS ,Science & Technology - Other Topics ,MICROBIAL FUEL-CELLS ,Feasibility Studies ,Printing ,lcsh:Q ,Biotechnology - Abstract
Microbial biophotovoltaic cells exploit the ability of cyanobacteria and microalgae to convert light energy into electrical current using water as the source of electrons. Such bioelectrochemical systems have a clear advantage over more conventional microbial fuel cells which require the input of organic carbon for microbial growth. However, innovative approaches are needed to address scale-up issues associated with the fabrication of the inorganic (electrodes) and biological (microbe) parts of the biophotovoltaic device. Here we demonstrate the feasibility of using a simple commercial inkjet printer to fabricate a thin-film paper-based biophotovoltaic cell consisting of a layer of cyanobacterial cells on top of a carbon nanotube conducting surface. We show that these printed cyanobacteria are capable of generating a sustained electrical current both in the dark (as a ‘solar bio-battery’) and in response to light (as a ‘bio-solar-panel’) with potential applications in low-power devices., Cyanobacteria can be exploited to convert light energy into electrical current, however utilising them efficiently for power generation is a challenge. Here, the authors use a simple commercial inkjet printer to fabricate a thin-film paper-based biophotovoltaic cell capable of driving low-power devices.
- Published
- 2017
9. Determining the order of deposition of natural latent fingerprints and laser printed ink using chemical mapping with secondary ion mass spectrometry.
- Author
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Attard Montalto, Nicola, Ojeda, Jesús J., and Jones, Benjamin J.
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LASER printing ,SECONDARY ion mass spectrometry ,HUMAN fingerprints ,TIME-of-flight mass spectrometry ,IMAGING systems in chemistry ,LATENT semantic analysis ,FEASIBILITY studies - Abstract
Abstract: Time-of-flight secondary ion mass spectrometry (ToF-SIMS) chemical mapping was used to investigate the order of deposition of natural latent fingerprints and laser printed ink on paper. This feasibility study shows that sodium, potassium and C
3 H5 positive ions were particularly abundant endogenous components of the natural fingerprints and also present in the paper examined, but were mostly absent in the laser printed ink. Mapping of these ions enables the observation of friction ridges from latent prints on the ink surface, only when a fingerprint was deposited above the layer of ink. As a demonstration of proof of concept, blind testing of 21 samples from three donors resulted in a 100% success rate. The sensitivity of this technique was investigated within this trial through the examination of up to fifth depletion fingerprints and ageing of up to 28days. Migration of fingerprint and paper components to the ink surface, although observed with increased ageing time, was not found to compromise determination of the deposition sequence. [Copyright &y& Elsevier]- Published
- 2013
- Full Text
- View/download PDF
10. Constraints on general motions for camera calibration with one-dimensional objects
- Author
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Qi, Fei, Li, Qihe, Luo, Yupin, and Hu, Dongcheng
- Subjects
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PAPER , *CALIBRATION , *EXAMPLE , *FEASIBILITY studies - Abstract
Abstract: This paper focuses on two problems in camera calibration with one-dimensional (1D) objects: (a) to find out the general motion patterns well suited for solving the calibration problem, and (b) to improve the robustness and accuracy of the method. Firstly, a sufficient and necessary condition for the solvability of 1D calibration with general motions is proved. Then the special motion of tossing a 1D object is provided as an example to illustrate the correctness and feasibility of this condition. After that some practical issues on obtaining the solution are inspected. By avoiding singularities, the precision and robustness of the method are improved: the relative mean errors are reduced to less than 5% at the noise level of one pixel which surpasses the state-of-the-art methods of the same category. [Copyright &y& Elsevier]
- Published
- 2007
- Full Text
- View/download PDF
11. Wave intensity analysis in the internal carotid artery of hypertensive subjects using phase-contrast MR angiography and preliminary assessment of the effect of vessel morphology on wave dynamics
- Author
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Neumann, S, Sophocleous, F, Kobetic, M D, Hart, E C, Nightingale, A K, Parker, K H, Hamilton, M K, and Biglino, G
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Paper ,Male ,Focus on Analysis and Measurement of the Arterial Pulse Wave Waveform ,hypertension ,reservoir pressure ,statistical shape modelling ,blood pressure ,internal carotid artery ,Blood Pressure Determination ,Middle Aged ,Image Interpretation, Computer-Assisted ,cardiovascular system ,Feasibility Studies ,Humans ,Female ,wave intensity analysis ,Aorta ,Carotid Artery, Internal ,Magnetic Resonance Angiography - Abstract
Objective: Hypertension is associated with reduced cerebral blood flow, but it is not known how this impacts on wave dynamics or potentially relates to arterial morphology. Given the location of the internal carotid artery (ICA) and risks associated with invasive measurements, wave dynamics in this artery have not been extensively assessed in vivo. This study explores the feasibility of studying wave dynamics in the internal carotid artery non-invasively. Approach: Normotensive, uncontrolled and controlled hypertensive participants were recruited (daytime ambulatory blood pressure 135/85 mmHg, respectively; n = 38). Wave intensity, reservoir pressure and statistical shape analyses were performed on the right ICA and ascending aorta high-resolution phase-contrast magnetic resonance angiography data. Main results: Wave speed in the aorta was significantly lower in normotensive compared to hypertensive participants (6.7 ± 1.8 versus 11.2 ± 6.2 m s−1 for uncontrolled and 11.8 ± 4.6 m s−1 for controlled hypertensives, p = 0.02), whilst there were no differences in wave speed in the ICA. There were no significant differences between the groups for the wave intensity or reservoir pressure. Interestingly, a significant association between the anatomy of the ICA and wave energy (FCW and size, r2 = 0.12, p = 0.04) was found. Significance: This study shows it is feasible to study wave dynamics in the ICA non-invasively. Whilst changes in aortic wave speed confirmed an expected increase in arterial stiffness, this was not observed in the ICA. This might suggest a protective mechanism in the cerebral circulation, in conjunction with the effect of vessel tortuosity. Furthermore, it was observed that ICA shape correlated with wave energy but not wave speed.
- Published
- 2018
12. Legal Influence and Educational Policy in Special Education.
- Author
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Prasse, David P.
- Subjects
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SPECIAL education , *EDUCATION policy , *UNDUE influence , *PAPER , *FEASIBILITY studies , *SYMPTOMS , *COURTS , *SCIENTIFIC knowledge - Abstract
The recommendations of the National Academy of Sciences (NAS) panel are critiqued from a perspective of broad educational policy and legal influence. The report and the accompanying background papers are endorsed with general acceptance of problem identificaion and formulation. However, the report is challenged for recommendations that are too narrowly conceived, raising questions as ro viability of implementation. Specific issues addressed include treating disproportionate placement as a symptom versus problem, legal and professional policy barriers to implementing the report's recommendations, and the role of courts in resolving scientific disputes and programatic concerns. [ABSTRACT FROM AUTHOR]
- Published
- 1988
- Full Text
- View/download PDF
13. Toward adaptive radiotherapy for lung patients: feasibility study on deforming planning CT to CBCT to assess the impact of anatomical changes on dosimetry
- Author
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Cole, A J, Veiga, C, Johnson, U, D’Souza, D, Lalli, N K, and McClelland, J R
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Paper ,Male ,Lung Neoplasms ,Radiotherapy Planning, Computer-Assisted ,cone beam CT ,Radiotherapy Dosage ,Spiral Cone-Beam Computed Tomography ,Middle Aged ,lung cancer ,adaptive radiotherapy ,Feasibility Studies ,Humans ,Female ,Radiotherapy, Conformal ,deformable image registration ,Algorithms - Abstract
Changes in lung architecture during a course of radiotherapy can alter the planned dose distribution to the extent that it becomes clinically unacceptable. This study aims to validate a quantitative method of determining whether a replan is required during the course of conformal radiotherapy. The proposed method uses deformable image registration (DIR) to flexibly map planning CT (pCT) data to the anatomy of online CBCT images. The resulting deformed CT (dCT) images are used as a basis for assessing the effect of anatomical change on dose distributions. The study used retrospective data from a sample of seven replanned lung patients. The settings of an in-house, open-source DIR algorithm were first optimised for CT-to-CBCT registrations of the anatomy of the thorax. Using these optimised parameters, each patient’s pCT was deformed to the CBCT acquired immediately before the replan. Registration accuracy was rigorously validated both geometrically and dosimetrically to confirm that the dCTs could reliably be used to inform replan decisions. A retrospective evaluation of the changes in dose delivered over time was then carried out for a single patient to demonstrate the clinical application of the proposed method. The geometric analysis showed good agreement between deformed structures and those same structures manually outlined on the CBCT images. Results were consistently better than those achieved with rigid-only registration. In the dosimetric analysis, dose distributions derived from the dCTs were found to match closely to the ‘gold standard’ replan CT (rCT) distributions across dose volume histogram and absolute dose difference measures. The retrospective analysis of serial CBCTs of a single patient produced reliable quantitative assessment of the dose delivery. Had the proposed method been available at the time of treatment, it would have enabled a more objective replan decision. DIR is a valuable clinical tool for dose recalculation in adaptive radiotherapy protocols for lung cancer patients.
- Published
- 2018
14. A comparison of smartphone and paper data-collection tools in the Burden of Obstructive Lung Disease (BOLD) study in Gezira state, Sudan
- Author
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Peter Burney, R Robinson, Kevin Mortimer, S. Bertel Squire, Asma Elsony, Rachael Thomson, Rana Ahmed, Rasmus Malmborg, Kodgule, Rahul, and Wellcome Trust
- Subjects
Male ,Rural Population ,Questionnaires ,Pulmonology ,020205 medical informatics ,Electronic data capture ,Physiology ,lcsh:Medicine ,Social Sciences ,Pilot Projects ,02 engineering and technology ,Pathology and Laboratory Medicine ,ELECTRONIC DATA CAPTURE ,Medical Records ,Sudan ,Geographical Locations ,Random Allocation ,Habits ,0302 clinical medicine ,Cohen's kappa ,Sociology ,Surveys and Questionnaires ,Smoking Habits ,Medicine and Health Sciences ,Coughing ,0202 electrical engineering, electronic engineering, information engineering ,Electronic Health Records ,Public and Occupational Health ,030212 general & internal medicine ,lcsh:Science ,Medical History Taking ,Observer Variation ,education.field_of_study ,wa_30 ,Schools ,Multidisciplinary ,Data Collection ,Smoking ,wa_900 ,Information quality ,Middle Aged ,Socioeconomic Aspects of Health ,Obstructive lung disease ,Multidisciplinary Sciences ,Open data ,Research Design ,Science & Technology - Other Topics ,Engineering and Technology ,Female ,Smartphone ,Symptom Assessment ,wf_600 ,Research Article ,Adult ,Paper ,wa_950 ,Adolescent ,General Science & Technology ,Population ,Equipment ,Research and Analysis Methods ,Sampling Studies ,Education ,Young Adult ,03 medical and health sciences ,Signs and Symptoms ,Diagnostic Medicine ,Environmental health ,MD Multidisciplinary ,medicine ,Humans ,Lung Diseases, Obstructive ,education ,c941fbbd ,Aged ,Communication Equipment ,Behavior ,Science & Technology ,Survey Research ,Data collection ,business.industry ,lcsh:R ,Biology and Life Sciences ,medicine.disease ,Health Care ,Cross-Sectional Studies ,Dyspnea ,Data quality ,People and Places ,Africa ,Feasibility Studies ,lcsh:Q ,Forms and Records Control ,Cell Phones ,Physiological Processes ,business - Abstract
Introduction \ud Data collection using paper-based questionnaires can be time consuming and return errors affect data accuracy, completeness, and information quality in health surveys. We compared smartphone and paper-based data collection systems in the Burden of Obstructive Lung Disease (BOLD) study in rural Sudan. \ud Methods \ud This exploratory pilot study was designed to run in parallel with the cross-sectional household survey. The Open Data Kit was used to programme questionnaires in Arabic into smartphones. We included 100 study participants (83% women; median age = 41.5 ± 16.4 years) from the BOLD study from 3 rural villages in East-Gezira and Kamleen localities of Gezira state, Sudan. Questionnaire data were collected using smartphone and paper-based technologies simultaneously. We used Kappa statistics and inter-rater class coefficient to test agreement between the two methods. Results Symptoms reported included cough (24%), phlegm (15%), wheezing (17%), and shortness of breath (18%). One in five were or had been cigarette smokers. The two data collection methods varied between perfect to slight agreement across the 204 variables evaluated (Kappa varied between 1.00 and 0.02 and inter-rater coefficient between 1.00 and -0.12). Errors were most commonly seen with paper questionnaires (83% of errors seen) vs smartphones (17% of errors seen) administered questionnaires with questions with complex skip-patterns being a major source of errors in paper questionnaires. Automated checks and validations in smartphone-administered questionnaires avoided skip-pattern related errors. Incomplete and inconsistent records were more likely seen on paper questionnaires. \ud Conclusion \ud Compared to paper-based data collection, smartphone technology worked well for data collection in the study, which was conducted in a challenging rural environment in Sudan. This approach provided timely, quality data with fewer errors and inconsistencies compared to paper-based data collection. We recommend this method for future BOLD studies and other population-based studies in similar settings.
- Published
- 2018
15. Molten film high-intensity paper dryer. Final report for reporting period August 16, 1996 through February 15, 1997
- Published
- 1998
16. Association score testing for rare variants and binary traits in family data with shared controls
- Author
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Ellen M. Wijsman and Mohamad Saad
- Subjects
Paper ,Male ,Linkage disequilibrium ,0206 medical engineering ,Quantitative Trait Loci ,Context (language use) ,02 engineering and technology ,Computational biology ,Biology ,Bioinformatics ,Generalized linear mixed model ,Linkage Disequilibrium ,03 medical and health sciences ,Gene Frequency ,Missing heritability problem ,Humans ,Computer Simulation ,Association (psychology) ,Molecular Biology ,Allele frequency ,030304 developmental biology ,Genetic association ,0303 health sciences ,Models, Genetic ,Computational Biology ,Genetic Variation ,High-Throughput Nucleotide Sequencing ,Sequence Analysis, DNA ,Pedigree ,Case-Control Studies ,Trait ,Linear Models ,Feasibility Studies ,Female ,020602 bioinformatics ,Information Systems ,Genome-Wide Association Study - Abstract
Genome-wide association studies have been an important approach used to localize trait loci, with primary focus on common variants. The multiple rare variant-common disease hypothesis may explain the missing heritability remaining after accounting for identified common variants. Advances of sequencing technologies with their decreasing costs, coupled with methodological advances in the context of association studies in large samples, now make the study of rare variants at a genome-wide scale feasible. The resurgence of family-based association designs because of their advantage in studying rare variants has also stimulated more methods development, mainly based on linear mixed models (LMMs). Other tests such as score tests can have advantages over the LMMs, but to date have mainly been proposed for single-marker association tests. In this article, we extend several score tests (χcorrected2, WQLS, and SKAT) to the multiple variant association framework. We evaluate and compare their statistical performances relative with the LMM. Moreover, we show that three tests can be cast as the difference between marker allele frequencies (AFs) estimated in each of the group of affected and unaffected subjects. We show that these tests are flexible, as they can be based on related, unrelated or both related and unrelated subjects. They also make feasible an increasingly common design that only sequences a subset of affected subjects (related or unrelated) and uses for comparison publicly available AFs estimated in a group of healthy subjects. Finally, we show the great impact of linkage disequilibrium on the performance of all these tests.
- Published
- 2017
17. Wastepaper recycling in the packaging industry. (Latest citations from Packaging Science and Technology Abstracts database). Published Search
- Published
- 1993
18. Development of 500/600-kV solid-type nonpressurized oil-paper dc cable
- Author
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McKean, A [Cablec Corp., Yonkers, NY (United States)]
- Published
- 1992
19. Development of 500/600-kV solid-type nonpressurized oil-paper dc cable. Final report
- Author
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McKean, A [Cablec Corp., Yonkers, NY (United States)]
- Published
- 1992
20. Carbon nanotubes buckypapers for potential transdermal drug delivery
- Author
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Alex Schwengber, D. Zilli, Ana Lea Cukierman, Pablo Ricardo Bonelli, and Héctor Juan Prado
- Subjects
Drug ,Paper ,Materials science ,CIENCIAS MÉDICAS Y DE LA SALUD ,Chemical structure ,media_common.quotation_subject ,Ciencias de la Salud ,Bioengineering ,Nanotechnology ,Buckypaper ,Carbon nanotube ,INGENIERÍAS Y TECNOLOGÍAS ,BUCKYPAPERS ,Administration, Cutaneous ,FLURBIPROFEN ,CARBON NANOTUBES ,law.invention ,Biomaterials ,Diffusion ,Nanopores ,Differential scanning calorimetry ,Nanocapsules ,law ,Materials Testing ,Particle Size ,media_common ,Transdermal ,Nanotecnología ,Nanotubes, Carbon ,Anti-Inflammatory Agents, Non-Steroidal ,TRANSDERMAL DRUG DELIVERY ,Nano-materiales ,Amorphous solid ,CLONIDINE HYDROCHLORIDE ,Otras Ciencias de la Salud ,Absorption, Physicochemical ,Flurbiprofen ,Mechanics of Materials ,Delayed-Action Preparations ,Surface modification ,Feasibility Studies ,Fullerenes - Abstract
Drug loaded buckypapers based on different types of carbon nanotubes (CNTs) were prepared and characterized in order to evaluate their potentialities for the design of novel transdermal drug delivery systems. Lab-synthesized CNTs as well as commercial samples were employed. Clonidine hydrochloride was used as model drug, and the influence of composition of the drug loaded buckypapers and processing variables on in vitro release profiles was investigated. To examine the influence of the drug nature the evaluation was further extended to buckypapers prepared with flurbiprofen and one type of CNTs, their selection being based on the results obtained with the former drug. Scanning electronic microscopy images indicated that the model drugs were finely dispersed on the CNTs. Differential scanning calorimetry, and X-ray diffraction pointed to an amorphous state of both drugs in the buckypapers. A higher degree of CNT-drug superficial interactions resulted in a slower release of the drug. These interactions were in turn affected by the type of CNTs employed (single wall or multiwall CNTs), their functionalization with hydroxyl or carboxyl groups, the chemical structure of the drug, and the CNT:drug mass ratio. Furthermore, the application of a second layer of drug free CNTs on the loaded buckypaper, led to decelerate the drug release and to reduce the burst effect. Fil: Schwengber, Alex. Universidad de Buenos Aires. Programa de Investigación y Desarrollo de Fuentes Alternativas de Materias Primas y Energía; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Prado, Héctor Juan. Universidad de Buenos Aires. Programa de Investigación y Desarrollo de Fuentes Alternativas de Materias Primas y Energía; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Zilli, Dario Adrian. Universidad de Buenos Aires. Programa de Investigación y Desarrollo de Fuentes Alternativas de Materias Primas y Energía; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Bonelli, Pablo Ricardo. Universidad de Buenos Aires. Programa de Investigación y Desarrollo de Fuentes Alternativas de Materias Primas y Energía; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Cukierman, Ana Lea. Universidad de Buenos Aires. Programa de Investigación y Desarrollo de Fuentes Alternativas de Materias Primas y Energía; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
- Published
- 2015
21. Internet-based guided self-help for parents of children on cancer treatment : A randomized controlled trial
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Martin Cernvall, Gustaf Ljungman, Per Carlbring, Lisa Ljungman, and Louise von Essen
- Subjects
Paper ,Adult ,Male ,Parents ,medicine.medical_specialty ,Adolescent ,Experimental and Cognitive Psychology ,Pediatrics ,law.invention ,Self-help ,Stress Disorders, Post-Traumatic ,Randomized controlled trial ,Internet based ,law ,Intervention (counseling) ,Neoplasms ,medicine ,cancer ,Humans ,Self report ,Child ,Internet ,business.industry ,Pediatrik ,Middle Aged ,posttraumatic stress ,Cancer treatment ,Psychiatry and Mental health ,Posttraumatic stress ,Child, Preschool ,Therapy, Computer-Assisted ,Papers ,oncology ,randomized controlled trial ,Physical therapy ,Feasibility Studies ,The Internet ,Female ,Self Report ,business ,internet‐based intervention ,Clinical psychology - Abstract
Objective The aim of the study was to investigate the feasibility and preliminary efficacy of an Internet‐based guided self‐help intervention for posttraumatic stress symptoms (PTSS) and related symptoms in parents of children on cancer treatment. Methods Parents of children on cancer treatment, who fulfilled the modified symptom criteria on the PTSD Checklist, were randomly allocated to the intervention or to a wait‐list control condition. The intervention group accessed a 10‐week guided self‐help program via the Internet based on principles from cognitve behavior therapy. The primary outcome PTSS and the secondary outcomes depression and anxiety were assessed by self‐report preintervention and postintervention. Results Seven hundred forty‐seven parents were approached and informed about the study, 92 were assessed for eligibility, and 58 were included and randomized to the intervention (n = 31) or wait list (n = 27). Eightteen participants completed the intervention. Intention‐to‐treat analyses indicated a significant effect of the intervention on PTSS with a large between‐group effect size at postassessment (Cohen's d = 0.88). The intervention group reported reductions in PTSS with a large within‐group effect size (d = 1.62) compared with a minimal reduction in the wait‐list group (d = 0.09). There was a significant intervention effect on depression and anxiety and reductions in the intervention group with large within‐group effect sizes (d = 0.85–1.09). Conclusions Findings indicate a low enrollment rate and considerable attrition but also that Internet‐based guided self‐help shows promise for parents of children on cancer treatment who report a high level of PTSS and would like to take part in an Internet‐based intervention. © 2015 The Authors. Psycho‐Oncology published by John Wiley & Sons, Ltd.
- Published
- 2015
22. Industrial complexes and their relevance for pulp and paper mills
- Author
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Sengupta, S
- Published
- 1980
23. Cellulose insulation: a look beyond the newsprint
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Manley, F
- Published
- 1978
24. Use of source-separated waste paper as a biomass fuel
- Author
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Tchobanoglous, G
- Published
- 1980
25. Compressed air offers transmission path to urban areas. [DAMUT (ducted air medium underground transmission) system]
- Author
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Koekebakker, J
- Published
- 1976
26. Ethanol production from acid hydrolyzed waste cellulose
- Author
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Thomas, D
- Published
- 1979
27. Recycling opportunities for neighbourhoods and communities
- Author
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Thomas, C
- Published
- 1981
28. Water reuse in a paper reprocessing plant. Final report
- Author
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Hogan, C
- Published
- 1976
29. Optimization of office paper recovery systems. Final report
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- 1977
30. Source separation: the community awareness program in Somerville and Marblehead, Massachusetts
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- 1976
31. Evaluation of alternatives to open burning of forest and agricultural residues (other than rice straw) in California
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Smith, W
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- 1982
32. The US pulp and paper industry: An energy perspective
- Author
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Lowitt, H
- Published
- 1988
33. Decision support in psychiatry – a comparison between the diagnostic outcomes using a computerized decision support system versus manual diagnosis
- Author
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Uno Fors and Lars G Bergman
- Subjects
Paper ,Decision support system ,medicine.medical_specialty ,Diagnostic methods ,Time Factors ,Writing ,education ,Computer support ,Expert Systems ,Health Informatics ,computer.software_genre ,lcsh:Computer applications to medicine. Medical informatics ,Clinical decision support system ,Health informatics ,medicine ,Humans ,Diagnosis, Computer-Assisted ,Medical diagnosis ,Diagnostic Errors ,Psychiatry ,Pencil (mathematics) ,business.industry ,Mental Disorders ,Health Policy ,Decision Support Systems, Clinical ,Expert system ,Computer Science Applications ,Diagnostic and Statistical Manual of Mental Disorders ,lcsh:R858-859.7 ,Feasibility Studies ,Clinical Competence ,business ,computer ,Research Article - Abstract
Background Correct diagnosis in psychiatry may be improved by novel diagnostic procedures. Computerized Decision Support Systems (CDSS) are suggested to be able to improve diagnostic procedures, but some studies indicate possible problems. Therefore, it could be important to investigate CDSS systems with regard to their feasibility to improve diagnostic procedures as well as to save time. Methods This study was undertaken to compare the traditional 'paper and pencil' diagnostic method SCID1 with the computer-aided diagnostic system CB-SCID1 to ascertain processing time and accuracy of diagnoses suggested. 63 clinicians volunteered to participate in the study and to solve two paper-based cases using either a CDSS or manually. Results No major difference between paper and pencil and computer-supported diagnosis was found. Where a difference was found it was in favour of paper and pencil. For example, a significantly shorter time was found for paper and pencil for the difficult case, as compared to computer support. A significantly higher number of correct diagnoses were found in the diffilt case for the diagnosis 'Depression' using the paper and pencil method. Although a majority of the clinicians found the computer method supportive and easy to use, it took a longer time and yielded fewer correct diagnoses than with paper and pencil. Conclusion This study could not detect any major difference in diagnostic outcome between traditional paper and pencil methods and computer support for psychiatric diagnosis. Where there were significant differences, traditional paper and pencil methods were better than the tested CDSS and thus we conclude that CDSS for diagnostic procedures may interfere with diagnosis accuracy. A limitation was that most clinicians had not previously used the CDSS system under study. The results of this study, however, confirm that CDSS development for diagnostic purposes in psychiatry has much to deal with before it can be used for routine clinical purposes.
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- View/download PDF
34. A Feasibility Study in Assessing Practical Maths
- Author
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Marsh, June
- Published
- 1975
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