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Copyright of Selcuk University Journal of Science Faculty / Selçuk Üniversitesi fen Fakültesi fen Dergisi is the property of Selcuk University Journal of Science Faculty and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In this research, environment-friendly composite membranes based on alginate (ALG) and bioglass nanoparticles (BGs) were prepared by the solvent casting technique and utilized as adsorbents for the elimination of methylene blue (MB) from water. Zeta potential of the particles was determined to be -24.9 mV by laser dynamic light scattering (DLS), and their sizes were found to be 773 and 777 nm by transmission electron microscopy (TEM) and DLS analysis, respectively. Atomic force microscope (AFM) analysis revealed that increasing the BGs content from 1 to 5% w/v caused the root mean square roughness of membranes to increase from 159.38 to 182.03 nm. The adsorption process was successfully modeled and optimized using a hybrid response surface methodology integrated central composite design (RSM-CCD). A statistical analysis was utilized to examine and optimize the effects of three important independent variables (concentration of BGs (1-5% w/v), pH of the solution (3-9), and initial dye level (15-45 mg L-1)) on MB adsorption performance. The findings indicated that the quadratic model was suitable for prediction of MB's removal. Optimized experimental parameters were found to be a pH of 9, a contact time of 120 min, an initial MB concentration of 45 mg L-1, and a BGs concentration of 1% (w/v). Freundlich isotherm and pseudo-second-order kinetic models were found to be the best-fitting models in isotherm and kinetic studies, respectively. Dubinin-Radushkevich (D-R) isotherm model predicted a chemical mechanism for MB adsorption onto the composite alginate membranes. [ABSTRACT FROM AUTHOR]

Hızlı nüfus artışı ve endüstriyelleşme ile her geçen gün artan su ihtiyacı ve atıksuların su kaynaklarına verdiği zararlar göz önüne alındığında, özellikle endüstriyel atıksuların deşarj öncesi arıtılması büyük önem taşımaktadır. Bu endüstriyel atıksuların başında yüksek su tüketimi ve boyar madde konsantrasyonu ile tekstil endüstrisi gelmektedir. Boyar maddelerin atıksulardan uzaklaştırılması için çeşitli fiziksel, kimyasal ve biyolojik arıtma yöntemleri kullanılmaktadır. Bu yöntemler arasında hem işletme hem performans açısından en kolay ve verimli yöntem adsorpsiyon olarak bilinmektedir. Ancak adsorbanın üretilmesi ve rejenerasyonu, yüksek maliyet ve enerji gerektirdiğinden, adsorpsiyon prosesinde sürdürülebilir malzemeye dayalı alternatif düşük maliyetli adsorbanların geliştirilmesi büyük önem taşımaktadır. Bu çalışmada yenilikçi ve çevre dostu selüloz nanokristal (SNK) katkılı aljinat adsorbanının üretilmesi ve metilen mavisi gideriminde kullanılması araştırılmıştır. Bu amaçla SNK katkılı aljinat bilyelerin metilen mavisi giderim performansının belirlenmesi için farklı adsorban konsantrasyonu ve farklı boyar madde konsantrasyonlarında kesikli adsorpsiyon deneyleri gerçekleştirilmiştir. En yüksek metilen mavisi giderim verimi, 100 mg/L boyar madde konsantrasyonu ve 0,5 g adsorban/50 mL boyar madde çözeltisi şartlarında gerçekleştirilen çalışma ile %35 olarak bulunmuştur. Ayrıca üretilen adsorbanın yeniden kullanılabilirliğinin araştırılması için bir seri adsorpsiyon-desorpsiyon çalışması gerçekleştirilmiş ve adsorbanın rejenerasyonu incelenmiştir.

İşlenen konulara göre yağlı boya tuval resimleri, dönemin sanatı, üslubu, sosyal yaşamı, inancı ve tarihi hakkında bilgi veren taşınabilir en önemli kültür varlıklarından biridir. Bu çalışmada çeşitli nedenlerden dolayı yağlı boya tuvallerde görülen kirlenmelerin biyopolimerik yapıda hidrojeller kullanılarak temizlenmesi amaçlanmıştır. Hidrojeller toksik madde içermemesi ve bunun yanında hızlı ve kolay bir teknikle hazırlanması yönünden birçok avantaja sahiptir. Hazırlanan hidrojeller ile tarihi eser niteliği taşıyan tuval resimlerindeki kirlenmeler yapıya zarar vermeden temizlenmiştir. Kolay ve bol bulunan aljinat ve doğal sakız biyopolimerleri ile hidrojel yapısında temizleme malzemesi hazırlanmıştır. Temizleme işlemlerinin test edilmesi için kimyasal yöntemler ile yaşlandırışmış tuvaller toz, kül ve is ile kirletilmiştir. Kullanılan hidrojel malzemeler kirletilen ve yaşlandırılan tuvallere uygulanması neticesinde sonuçlar farklı mikroskobik ve spektroskopik yöntemlerle incelenmiştir. Optik mikroskop, Taramalı Elektron Mikroskobu (SEM) ve Fourier Dönüşümlü Kızılötesi Spektrofotometresi (FT-IR) analiz yöntemleri kullanılarak malzemelerin karakterizasyonu gerçekleştirilmiştir.

Copyright of Karaelmas Science & Engineering Journal / Karaelmas Fen ve Mühendislik Dergisi is the property of Karaelmas Science & Engineering Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: The objective of this study was to prepare a controlled release system, which could be used in medical applications in order to treat infections at the host region. Methods: Microlayer films were prepared via solvent casting method. Films with 3-layers were prepared by using chitosan (CHI), gelatin (GEL) and alginate (ALG) in the form of CHI /ALG/CHI and CHI-GEL /ALG/CHI-GEL with or without ceftriaxone sodium (CS) which is loaded in the middle ALG layer. All films were crosslinked by exposing them to glutaraldehyde (GA) vapor for different (2 h, 10 h or 24 h) durations. Mechanical properties of the films and release kinetics of CS at three different pH conditions (pH 5.5, 7.4, and 10.0) were investigated. The antibacterial efficiency of the released CS against Escherichia coli was examined via agar spot test. Results: The results indicated that the presence of GEL in the upper and lower layers of the 3-layer construct prevented fragility and increased the mechanical strength of the films, whereas the presence of CS in the middle layer caused decrease in the mechanical properties. Crosslinking with GA did not demonstrate a significant effect on the release profile of CS, but due the interaction of chitosan with alginate and CS, the drug release was delayed. Antibacterial tests which were carried out by using the released media of drug loaded films displayed inhibition zone in agar spot tests against E. coli. Conclusion: It was concluded that multilayered films prepared by solvent casting can be good candidates as drug carrier devices in medical applications. [ABSTRACT FROM AUTHOR]

Purpose: The aim of this study was to assess the cytotoxicity of different types of alginate impression materials. Material and Method: Cavex CA37, A3KROM, ALGINPLUS FAST ve ORALGHINE alginate impression materials were used. According to the manufacturer’s instructions, alginates were mixed with serum physiological to obtain alginate specimens. Specimens were performed in sterile with ethylene oxide gas and then placed on to the L929 fibroblast cell culture. According to the 1999 ISO 10993-5 protochols, cytotoxicity were determined by means of agar overley test. Results: According to the lisis of the cells, ORALGH

The aim of this present study is to develop micro-beads for controlled release of Metoprolol succinate (MS). Different combinations of alginate and poloxamer 407 (PL) were taken to prepare beads by employing ionotropic gelation method, where CaCl2 used as gelling agent. FTIR technique was used to study the drug and polymers interaction. The prepared beads were evaluated for drug loading, entrapment efficiency, particle size and morphology, in vitro drug release and drug release kinetics. There were no shift in the major peaks of the pure drug was observed from the FTIR spectra, which indicates the absence of interaction between drug and polymers. The highest drug loading and entrapment efficiency were found to be 3.11 % and 35.67 %, respectively for the formulation FB1. The particle size was measured by sieving method and it was found that the particles were in the micron range for all the formulations. The morphology of the formulation FB4 was studied by SEM and the image showed irregular surface. The in vitro drug release study was carried out in pH 6.8 phosphate buffer for 12 hr at 37°C and the results demonstrate cumulative percentage of drug release was decreased with the increase in PL ratio in the composition that indicates controlled drug release. To know the mechanism of drug release the in vitro drug release data were fitted to zero order, first order, Higuchi and Korsmeyer-Peppas equation. The formulation FB4 showed highest correlation coefficient (r2) of 0.97 for Higuchi equation due to which it was selected as best formulation. The release exponent (n) of all the formulation were below 0.45 except FB4 (0.48) demonstrating Fickian diffusion is the drug release mechanism, whereas the formulation FB4 indicated non-Fickian diffusion i.e. diffusion and erosion were the mechanism. [ABSTRACT FROM AUTHOR]