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Your search keyword '"Clauvel, Jean-Pierre"' showing total 44 results
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44 results on '"Clauvel, Jean-Pierre"'

1. Pulmonary Arterial Hypertension Associated With Systemic Lupus Erythematosus: Results From the French Pulmonary Hypertension Registry

Author

Hachulla, Eric, Jais, Xavier, Cinquetti, Gaël, Clerson, Pierre, Rottat, Laurence, Launay, David, Cottin, Vincent, Habib, Gilbert, Prevot, Grégoire, Chabanne, Céline, Foïs, Eléna, Amoura, Zahir, Mouthon, Luc, Le Guern, Véronique, Montani, David, Simonneau, Gérald, Humbert, Marc, Sobanski, Vincent, Sitbon, Olivier, Balquet, Marie-Hélène, Ziza, Jean-Marc, Clauvel, Jean-Pierre, Brouet, Jean-Claude, Pison, Christophe, Chabot, Jean-François, Velly, Jean-François, Dos Santos, Pierre-Dominique, Meurice, Jean-Claude, Fauchais, Anne-Laure, Guillevin, Loïc, Cadranel, Jacques, Traclet, Julie, Mornex, Jean-François, Mabo, Philippe, and Didier, Alain

Published
2018
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5. A Comparison of Cell Activation, Exhaustion, and Expression of HIV Coreceptors and Restriction Factors in HIV-1- and HIV-2-Infected Nonprogressors

Author

Diallo, Mariama Sadjo, Samri, Assia, Charpentier, Charlotte, Bertine, Mélanie, Cheynier, Rémi, Thiébaut, Rodolphe, Matheron, Sophie, Collin, Fidéline, Braibant, Martine, Candotti, Daniel, Appay, Victor, Brun-Vézinet, Françoise, Chaghil, Nathalie, Descamps, Diane, Hosmalin, Anne, Pancino, Gianfranco, Manel, Nicolas, Marchand, Lucie, Pedroza-Martins, Livia, Sáez-Cirión, Asier, Agut, Henri, Clauvel, Jean-Pierre, Costagliola, Dominique, Debré, Patrice, Theodorou, Ioannis, Sicard, Didier, Viard, Jean-Paul, Barin, Francis, Vieillard, Vincent, Autran, Brigitte, Centre d'Immunologie et de Maladies Infectieuses (CIMI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Sorbonne Université (SU), Laboratoire de Virologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC), Equipe de Biostatistique, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR99-ISPED, Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service des maladies infectieuses et tropicales, Université Paris Diderot - Paris 7 (UPD7)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Epidémiologie, santé publique et développement, Virus, pseudo-virus: Morphogénèse et Antigénicité, Université de Tours (UT)-EA3856, CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM), and Université de Tours-EA3856

Subjects
0301 basic medicine, CD4-Positive T-Lymphocytes, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Ubiquitin-Protein Ligases, Immunology, Human immunodeficiency virus (HIV), HIV Infections, Biology, medicine.disease_cause, West africa, HIV Long-Term Survivors, Antiviral Restriction Factors, Tripartite Motif Proteins, 03 medical and health sciences, 0302 clinical medicine, Virology, medicine, Humans, 030212 general & internal medicine, ComputingMilieux_MISCELLANEOUS, virus diseases, 3. Good health, 030104 developmental biology, Infectious Diseases, HIV-2, HIV-1, [SDV.IMM]Life Sciences [q-bio]/Immunology, Cell activation
Abstract

Human immunodeficiency viruses induce rare attenuated diseases due either to HIV-1 in the exceptional long-term nonprogressors (LTNPs) or to HIV-2 in West Africa. To better understand characteristics of these two disease types we performed a multiplex comparative analysis of cell activation, exhaustion, and expression of coreceptors and restriction factors in CD4 T cells susceptible to harbor those viruses. We analyzed by flow cytometry the expression of HLA-DR, PD1, CCR5, CXCR6, SAMHD1, Blimp-1, and TRIM5α on CD4 T cell subsets from 10 HIV-1

Published
2020

19. Chlorambucil-associated pneumonitis

Author

Crestani, Bruno, Jaccard, Arnaud, Isreal-Biet, Dominique, Couderc, Louis-Jean, Frija, Jacques, and Clauvel, Jean-Pierre

Subjects
Bacterial pneumonia -- Causes of -- Complications and side effects, Chlorambucil -- Complications and side effects, Pneumonia -- Causes of -- Complications and side effects, Health, Complications and side effects, Causes of
Abstract

A patient developed an interstitial pneumonitis while receiving chlorambucil for a chronic lymphocytic leukemia (cumulative dose, 8,340 mg). Withdrawal of drug treatment was followed by rapid improvement in the clinical [...]

Published
1994

29. Non-inflammatory herpes simplex hepatitis in an adult with chronic neutropenia.

Author

Bernuau, Jacques, Rueff, Bernard, Clauvel, Jean-Pierre, Degott, Claude, Perol, Yvonne, and Benhamou, Jean-Pierre

Abstract

ABSTRACT- We report the case of a young woman with chronic neutropenia, in whom hepatitis, extensive herpetic eruption and herpes simplex viremia developed after genital herpetic ulceration. Although severe liver necrosis was present, the patient's death did not result from hepatic failure. No inflammatory cell infiltration was found circumscribing the multiple necrotic foci in the liver. This absence of inflammatory cell infiltration reflects the host's inability to normally restrain herpes simplex virus dissemination and, in this patient, might be the consequence of chronic neutropenia. [ABSTRACT FROM AUTHOR]

Published
1981
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31. Antinuclear Autoantibodies Specific for Lamins.

Author

Lassaoued, Kaiss, Guilly, Marie-Noelle, Danon, Francoise, Andre, Chantal, Dhumeaux, Daniel, Clauvel, Jean-Pierre, Brouet, Jean-Claude, Seligmann, Maxime, and Courvalin, Jean-Claude

Subjects
ANTINUCLEAR factors, AUTOIMMUNE diseases, AUTOANTIBODIES, PATIENTS
Abstract

Presents information on a study which examined the antinuclear autoantibodies of several patients with chronic autoimmune disorder for lamins. Methodology of the study; Results and discussion.

Published
1988
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44. Autoimmune cytopenias associated with autoantibodies to nuclear envelope polypeptides.

Author

Coppo P, Clauvel JP, Bengoufa D, Fuentes V, Gouilleux-Gruart V, Courvalin JC, and Lassoued K

Subjects
Adolescent, Adult, Aged, Anemia, Hemolytic, Autoimmune complications, Anemia, Hemolytic, Autoimmune drug therapy, Anemia, Hemolytic, Autoimmune immunology, Anemia, Hemolytic, Autoimmune pathology, Autoimmune Diseases complications, Autoimmune Diseases drug therapy, Autoimmune Diseases pathology, Coombs Test, Female, Follow-Up Studies, Humans, Immunoblotting, Liver Diseases complications, Liver Diseases pathology, Male, Middle Aged, Neutropenia complications, Neutropenia drug therapy, Neutropenia immunology, Neutropenia pathology, Pancytopenia complications, Pancytopenia drug therapy, Pancytopenia pathology, Peptides immunology, Purpura, Thrombocytopenic complications, Purpura, Thrombocytopenic drug therapy, Purpura, Thrombocytopenic immunology, Purpura, Thrombocytopenic pathology, Retrospective Studies, Treatment Outcome, Vasculitis complications, Vasculitis pathology, Autoantibodies immunology, Autoimmune Diseases immunology, Nuclear Envelope immunology, Nuclear Proteins immunology, Pancytopenia immunology
Abstract

A subset of anti-nuclear autoantibodies (ANA) are directed against nuclear envelope (NE) polypeptides and display by indirect immunofluorescence (IIF) a ring-like fluorescent pattern. We report herein 19 patients with autoimmune cytopenias associated with antibodies (Abs) to NE polypeptides. Anti-NE specificity was determined by immunoblot, using NE preparations and purified lamina fractions. Eleven sera reacted with lamin B(1), and two reacted with both lamin B(1) and an unidentified 150-kDa protein (p150). One serum reacted with only p150. Four sera reacted with lamins A and C, and one reacted with and an unidentified 52-kDa NE polypeptide (p52). Autoimmune cytopenias included hemolytic anemia (7 cases), thrombocytopenia (13 cases), and neutropenia (6 cases). Five patients had 2 (3 cases) or 3 (2 cases) different cytopenias. Antiphospholipid antibodies (APLA) were detected in 14 patients, 2 of whom experienced thromboembolic events. A liver disorder was present in 7 patients. Systemic lupus erythematosus and lupus-like syndrome were diagnosed in 11 and 2 patients, respectively. Cytopenias responded to steroids alone (13 patients), or together with intravenous immunoglobulins (2 patients), or cyclophosphamide (2 patients). Two patients did not require treatment. Our results suggest that anti-NE Abs need to be sought for in patients with peripheral cytopenias, particularly when they are associated with APLA and/or liver disorders. Their detection strongly suggests an autoimmune process. Such cytopenias are often manifestations of a lupus or lupus-like disease and are responsive to steroids.

Published
2004
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