410 results on '"Moffat, Jason"'
Search Results
2. Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
3. Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells
4. Salmonella exploits membrane reservoirs for invasion of host cells
5. A scalable platform for efficient CRISPR-Cas9 chemical-genetic screens of DNA damage-inducing compounds
6. The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
7. Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids
8. N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity
9. Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer
10. Author Correction: Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma
11. Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux
12. A cohesin traffic pattern genetically linked to gene regulation
13. The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers
14. Identifying cell receptors for the nanoparticle protein corona using genome screens
15. Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors
16. Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma
17. LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions
18. Efficient recovery of potent tumour-infiltrating lymphocytes through quantitative immunomagnetic cell sorting
19. High-content CRISPR screening
20. Multi-level cellular and functional annotation of single-cell transcriptomes using scPipeline
21. Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma
22. FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation
23. Analysis of combinatorial CRISPR screens with the Orthrus scoring pipeline
24. Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter.
25. Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies
26. Author Correction: Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux
27. Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
28. Functional genomics identifies new synergistic therapies for retinoblastoma
29. Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
30. Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform
31. A CD133-AKT-Wnt signaling axis drives glioblastoma brain tumor-initiating cells
32. Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies
33. High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting
34. Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells
35. Protocadherin-1 is essential for cell entry by New World hantaviruses
36. Digital microfluidic isolation of single cells for -Omics
37. Mammalian Cdk5 Is a Functional Homologue of the Budding Yeast Pho85 Cyclin-Dependent Protein Kinase
38. The shieldin complex mediates 53BP1-dependent DNA repair
39. CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
40. Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1–F-box interface
41. High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
42. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface
43. Identifying chemogenetic interactions from CRISPR screens with drugZ
44. Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
45. RNAi screen identifies essential regulators of human brain metastasis-initiating cells
46. Cytosolic detection of the bacterial metabolite HBP activates TIFA-dependent innate immunity
47. Impact of CRISPR in cancer drug discovery.
48. CD133-Targeted Niche-Dependent Therapy in Cancer: A Multipronged Approach
49. Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes
50. SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.