157 results on '"Varela-Centelles, Pablo"'
Search Results
2. Asymmetry of dental or joint anatomy or impaired chewing function contribute to chronic temporomandibular joint disorders
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Santana-Mora, Urbano, López-Cedrún, José, Suárez-Quintanilla, Juán, Varela-Centelles, Pablo, Mora, María Jesús, Da Silva, José Luís, Figueiredo-Costa, Fernanda, and Santana-Penín, Urbano
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- 2021
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3. Overall time interval (“Total diagnostic delay”) and mortality in symptomatic oral cancer: A U-shaped association
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Lopez-Cedrún, José L., Varela-Centelles, Pablo, Otero-Rico, Ana, Vázquez-Mahía, Inés, Seoane, Juan, Castelo-Baz, Pablo, and Seoane-Romero, Juan
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- 2020
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4. Short‐term performance of unilateral zygomatic implants: A case series.
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Cea‐Arestín, Pablo, Bilbao‐Alonso, Arturo, Varela‐Centelles, Pablo, Menéndez‐Lago, Carolina, and Seoane‐Lestón, Juan
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EDENTULOUS mouth ,CONTINUOUS functions ,MAXILLA - Abstract
The aim of this investigation is to contribute to clarify whether zygomatic unilateral implants are a feasible alternative for the rehabilitation of the atrophic maxilla. Six consecutive, unilaterally edentulous patients who received zygomatic implants gave their consent to enter this retrospective observational study. Fixtures were inserted according to the Zygomatic Anatomy‐Guided Approach and loaded with functional screwed restorations. All patients were compliant with their scheduled follow‐up appointments. Six tapered implants were considered, mostly (80%) 4.4 mm diameter 40–50 mm long. These fixtures had been in place for an average of 4.1 years (range: 5–144 months). No implant failures were observed, and continuous fixed‐prosthesis function was achieved throughout the follow‐up period with no loosening or fracture of prosthetic screws. Patients were satisfied with the treatment and experienced only minor complications. Unilateral zygomatic implants seem to be a feasible alternative that diminishes morbidity and treatment times with high‐survival rates for patients with atrophic posterior maxilla. [ABSTRACT FROM AUTHOR]
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- 2023
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5. Study of factors influencing preoperative detection of alveolar antral artery by CBCT in sinus floor elevation
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Varela-Centelles, Pablo, Loira, María, González-Mosquera, Antonio, Romero-Mendez, Amparo, Seoane, Juan, García-Pola, María José, and Seoane-Romero, Juan M.
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- 2020
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6. Accessibility to editorial information in Oral and Maxillofacial Surgery journals: The authors' point of view
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Castelo-Baz, Pablo, Leira-Feijoo, Yago, Seoane-Romero, Juan Manuel, Varela-Centelles, Pablo, and Seoane, Juan
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- 2015
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7. Diabetes mellitus and oral lichen planus: A systematic review and meta‐analysis.
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Mallah, Narmeen, Ignacio Varela‐Centelles, Pablo, Seoane‐Romero, Javier, and Takkouche, Bahi
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PUBLICATION bias , *META-analysis , *MEDICAL information storage & retrieval systems , *CONFIDENCE intervals , *SYSTEMATIC reviews , *DIABETES , *ORAL lichen planus , *PUBLIC health , *MEDLINE , *ODDS ratio , *SENSITIVITY & specificity (Statistics) - Abstract
Objective: To undertake a meta‐analysis of the association of Oral Lichen Planus (OLP) with diabetes, two diseases with an important impact on public health and the economy, but the evidence of which about their association is inconsistent. Methods: Relevant studies were localized by searching MEDLINE, EMBASE, Conference Proceedings, and other databases from inception to October 2020, without restrictions. The reference lists of included studies and of related reviews were also inspected. Global pooled odds ratios were calculated, and predefined subgroup analyses were performed. The heterogeneity between studies and publication bias was assessed and sensitivity analysis was carried out. Results: Thirty‐two studies were included in the meta‐analysis. Pooled ORs showed a moderate association between diabetes and OLP [OR: 1.87 (95%CI: 1.57, 2.34)]. The association is limited to studies carried out on adults only [OR: 2.12 (95%CI: 1.75, 2.57)] and is observed in all study designs. Globally, the heterogeneity was low to moderate. Studies carried out in European populations show a stronger association of diabetes and OLP than Asiatic studies [OR: 2.49 (95%CI: 1.87, 3.32) and 1.60 (95%CI: 1.25, 2.03), respectively]. Conclusions: Diabetes and OLP are moderately associated. Systematic diagnosis of diabetes in OLP patients could prove useful. [ABSTRACT FROM AUTHOR]
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- 2022
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8. Predictors for Tumor Recurrence After Primary Definitive Surgery for Oral Cancer
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Vázquez-Mahía, Inés, Seoane, Juan, Varela-Centelles, Pablo, Tomás, Inmaculada, García, Augusto Álvarez, and López Cedrún, José Luis
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- 2012
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9. Early oral cancer diagnosis: The Aarhus statement perspective. A systematic review and meta-analysis
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Seoane, Juan, Alvarez–Novoa, Pablo, Gomez, Iria, Takkouche, Bahi, Diz, Pedro, Warnakulasiruya, Saman, Seoane–Romero, Juan M., Varela–Centelles, Pablo, and Eisele, David W.
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- 2016
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10. Technological Bases for Teledermatopathology: State of the Art
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DeAgustín, Domingo, Sanmartín, Jose, Varela-Centelles, Pablo, Vidal, Santiago, and Seoane, Juan
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- 2016
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11. Covid-19 pandemic: A new contributing factor to diagnostic and treatment delay in oral cancer patients
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Varela-Centelles, Pablo, Seoane, Juan, Bilbao, Arturo, and Seoane-Romero, Juan
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- 2021
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12. Available web-based dental implants information for patients. How good is it?
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Leira-Feijoo, Yago, Ledesma-Ludi, Yanina, Seoane-Romero, Juan M., Blanco-Carrión, Juan, Seoane, Juan, and Varela-Centelles, Pablo
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- 2015
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13. Neurological adverse events related to lip biopsy in patients suspicious for Sjögren’s syndrome: a systematic review and prevalence meta-analysis
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Varela Centelles, Pablo, Sánchez-Sánchez, Mariña, Costa-Bouzas, Julián, Seoane-Romero, Juan Manuel, Seoane, Juan, and Takkouche, Bahi
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- 2014
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14. Membrane Perforation in Sinus Floor Elevation – Piezoelectric Device versus Conventional Rotary Instruments for Osteotomy: An Experimental Study
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Seoane, Juan, López-Niño, Javier, García-Caballero, Lucía, Seoane-Romero, Juan Manuel, Tomás, Inmaculada, and Varela-Centelles, Pablo
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- 2013
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15. Immunohistochemical analysis of epithelium adjacent to lip cancer: A meta‐analysis.
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Varela‐Centelles, Pablo, Gonzalez‐Moles, Miguel Ángel, Seoane‐Romero, Javier, Leira‐Feijoo, Yago, Takkouche, Bahi, and Seoane‐Romero, Juan Manuel
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META-analysis , *MEDICAL information storage & retrieval systems , *STAINS & staining (Microscopy) , *IMMUNOHISTOCHEMISTRY , *SYSTEMATIC reviews , *EPITHELIUM , *MOLECULAR biology , *CANCER patients , *DISEASE prevalence , *TUMOR markers , *MEDLINE , *SQUAMOUS cell carcinoma ,LIP tumors - Abstract
Objectives: To identify the immunohistochemical pattern of non‐tumoral epithelium adjacent to lip cancer (ANTE) to unveil molecular alterations and potential biomarkers in lip cancer patients. Materials and Methods: A systematic search at MEDLINE, EMBASE and proceedings Web of Science, OpenGrey and WorldCat. The PICOS outline (Population: lip cancer patients; Intervention: immunostaining with biomarkers in surgical specimens; Comparisons: ANTE versus LC; Outcomes: primary—to identify the immunohistochemical pattern of peritumoral epithelium and secondary—to assess the immunoreactivity of LC epithelium; and Study design: cross‐sectional, case‐control and cohort studies). Results: A total of 339 records were identified. Seven studies reporting on ANTE and LCs were included in the qualitative synthesis, and 4 of them (p53 immunostaining) were selected for meta‐analysis. In the ANTE group, the pooled prevalence of p53 was 0.74 (95% CI: 0.66 – 0.82), while in the lip squamous cell carcinoma group this prevalence was 0.83 (95% CI: 0.75 – 0.89). Conclusions: Similar immunoexpression was found in lip epithelium adjacent to lip carcinoma, even in epithelia with normal appearance or mild histological alterations. The role of biomarkers in the follow‐up of actinic cheilitis patients deserves additional clinical assessment. [ABSTRACT FROM AUTHOR]
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- 2022
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16. Assembling a consensus on actinic cheilitis: A Delphi study.
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Seoane, Juan, Warnakulasuriya, Saman, Bagán, José Vicente, Aguirre‐Urizar, José Manuel, López‐Jornet, Pía, Hernández‐Vallejo, Gonzalo, González‐Moles, Miguel Ángel, Pereiro‐Ferreiros, Manuel, Seoane‐Romero, Javier, and Varela‐Centelles, Pablo
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CHEILITIS ,CONSENSUS (Social sciences) ,DIAGNOSIS ,INFLAMMATION treatment ,BIOPSY ,ORAL diseases - Abstract
Aims: To discuss the terminology to define and classify actinic cheilitis (AC) and to build a consensus on the diagnostic and therapeutic approaches to AC. Methods: Two‐round Delphi study using a questionnaire including 34 closed sentences (9 on terminology and taxonomy, 5 on potential for malignant transformation, 12 on diagnostic aspects, 8 on treatment) and 8 open questions. Experts' agreement was rated using a Likert scale (1–7). Results: A consensus was reached on 24 out 34 statements (73.5%) and on 5 out of 8 (62.5%) close‐ended questions. The response rate was identical in both rounds (attrition of 0%). AC is the term with the highest agreement (median of 7 (strongly agree; IQR: 6–7)) and the lowest dispersion (VC = 21.33). 'Potentially malignant disorder' was the preferred classification group for AC (median of 7) and 85.6% of participants showing some level of agreement (CV < 50). Experts (66.75%) consider AC a clinical term (median: 7; IQR: 4–7) and believe definitive diagnosis can be made clinically (median: 6; IQR: 5–7), particularly by inspection and palpation (median: 5; IQR: 4–6). Histopathological confirmation is mandatory for the management of AC (median: 5; IQR: 2.5–7), even for homogeneous lesions (median: 5; IQR: 3.5–6). Consensus was reached on all treatment statements (VC < 50). Conclusions: AC is a potentially malignant disorder with a significant lack of agreement on diagnostic criteria, procedures, biopsy indications and the importance of techniques to assist in biopsy. A consensus was reached on nomenclature and management of this disorder. [ABSTRACT FROM AUTHOR]
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- 2021
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17. PROLIFERATIVE ACTIVITY AND DIAGNOSTIC DELAY IN ORAL CANCER
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Seoane, Juan, Pita-Fernández, Salvador, Gómez, Iria, Vazquez, Inés, López-Cedrún, José Luis, De Agustin, Domingo, and Varela-Centelles, Pablo
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- 2010
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18. Is diagnostic delay related to advanced-stage oral cancer? A meta-analysis
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Gómez, Iria, Seoane, Juan, Varela-Centelles, Pablo, Diz, Pedro, and Takkouche, Bahi
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- 2009
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19. Assessment of dental implant stability in osseodistraction-generated bone: a resonance frequency analysis
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Bilbao, Arturo, Hernández-De Oliveira, M., Varela-Centelles, Pablo I., and Seoane, J.
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- 2009
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20. Metastatic tumours to the oral cavity: a survival study with a special focus on gingival metastases
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Seoane, Juan, Van der Waal, Isaäc, Van der Waal, Rutger I. F., Cameselle-Teijeiro, José, Antón, Iosu, Tardio, Antoni, Alcázar-Otero, Juan J., Varela-Centelles, Pablo, and Diz, Pedro
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- 2009
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21. Technological Bases for Teledermatopathology: State of the Art
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DeAgustín, Domingo, Sanmartín, Jose, Varela-Centelles, Pablo, Vidal, Santiago, and Seoane, Juan
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- 2008
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22. Online audio-visual information on oral cancer for Spanish-speaking laypersons. A cross-sectional study.
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Ulloa-Morales, Yaima, Negreira-Martínez, Francisco, Blanco-Hortas, Andrés, Patiño-Castiñeira, Berta, San-Román-Rodríguez, Elena, Varela-Centelles, Pablo, and Manuel Seoane-Romero, Juan
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ORAL cancer ,DELAYED diagnosis ,CROSS-sectional method ,MEDICAL personnel ,AUDIOVISUAL materials - Abstract
Background: Lack of knowledge and awareness of oral cancer seem to be the main causes of diagnostic delay. Online resources are often used by patients to obtain health/medical information. However, there are no reports on the quality and usefulness of oral cancer audio-visual resources in Spanish. The aims of this investigation were to disclose the type of information about oral cancer available, and whether it may be useful to shorten the patients' oral cancer appraisal time-interval. Material and Methods: Cross-sectional study undertaken at three video-sharing sites on October, 13th 2019. Keywords: "Cáncer oral"; "cáncer de boca". The first 100 results in each viewing list were retrieved by three reviewers. Demographical data was recorded, and interaction indexes, viewing rates, comprehensiveness, and usefulness were calculated for each video. The presence of non-scientifically supported information was also assessed. A descriptive analysis was undertaken, and relationships between variables were explored using the Spearman correlation test. Results: A total of 127 videos were selected. They were produced mainly by mass-media (46.5%; n=59) and their length ranged from 0.28 to 105.38 minutes (median 4.15 minutes; IQR: 2.34-9.67). The most viewed video (10,599,765 views; visualization rate 726,508.9) scored 0 both in usefulness and comprehensiveness. The most useful video gathered 44,119 views (visualization rate 2.033.13). A highly significant positive correlation (0.643; p<0.001) could be observed between usefulness and comprehensiveness of the videos, together with negative correlations between the visualization rate and usefulness (-0.186; p<0.05), and visualization rate and comprehensiveness (-0.183; p<0.05). Conclusions: Online audio-visual material about oral cancer in Spanish is incomplete, of limited usefulness, and often includes non-scientifically supported information. Most of these resources are produced by mass media and healthcare professionals, with minor contributions from educational and healthcare institutions. Visualization rates negatively correlated with the usefulness and comprehensiveness of the contents in these digital objects. [ABSTRACT FROM AUTHOR]
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- 2021
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23. Early Diagnosis and Diagnostic Delay in Oral Cancer.
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Varela-Centelles, Pablo
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DELAYED diagnosis , *MOUTH tumors , *TIME , *SERIAL publications , *EARLY detection of cancer - Published
- 2022
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24. Primary care physicians and nurses: Targets for basic periodontal education.
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Varela‐Centelles, Pablo, Diz‐Iglesias, Pedro, Estany‐Gestal, Ana, Ulloa‐Morales, Yaima, Bugarín‐González, Rosendo, Seoane‐Romero, Juan M., Varela-Centelles, Pablo, Diz-Iglesias, Pedro, Estany-Gestal, Ana, Ulloa-Morales, Yaima, Bugarín-González, Rosendo, and Seoane-Romero, Juan M
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PRIMARY care ,PHYSICIANS ,NURSES ,DENTAL education ,EARLY diagnosis ,QUALITY of life ,PERIODONTIUM examination ,INTERPROFESSIONAL education - Abstract
Background: Early diagnosis may improve patients' quality of life and reduce the lifelong social and financial burden inherent to treatment. Growing evidence supports the importance of a healthy periodontium in systemic health. Diagnosis depends on the patient and the healthcare professional. As many patients seek physicians' advice first, this study aims at assessing periodontal knowledge in a general population and their primary care physicians and nurses.Methods: This is a cross-sectional study using an anonymous questionnaire applied to randomly selected laypersons (March to June 2016), and to physicians and nurses at their workplaces (October to December 2016) in Ourense, Spain. Sample size for the general population was determined by quota sampling.Results: A total of 1,469 people entered the study. All healthcare workers and 624 (47.1%) laypersons were familiar with periodontitis. Bacterial etiology of periodontitis was recognized by 25 (4%) laypersons, 23 (34.3%) physicians, and 11 (16.6%) nurses. The following periodontal problems were experienced: 1) gingival redness: laypersons 14.4%, physicians 16.4%, and nurses 21.2%; 2) gingival bleeding: laypersons 22.2%, physicians 50.7%, and nurses 50%; 3) tooth mobility: laypersons 34.9%, physicians 7.4%, and nurses 6%; and 4) bleeding while toothbrushing: laypersons 44.3%, physicians 8.9%, and nurses 15.1%. More than a third of laypersons (37%) think periodontitis is related to other health problems, together with 53% of physicians and 47% of nurses.Conclusions: Our results show a low degree of periodontal knowledge both amongst the public and their primary care physicians and nurses and unveil unreliable targets (primary healthcare workers) for educational interventions to improve early diagnosis and treatment of periodontal disorders. [ABSTRACT FROM AUTHOR]- Published
- 2018
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25. Oral cancer awareness in North-Western Spain: a population-based study.
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Varela-Centelles, Pablo, Seoane, Juan, Ulloa-Morales, Yaima, Estany-Gestal, Ana, Blanco-Hortas, Andrés, García-Pola, María J., and Seoane-Romero, Juan M.
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ORAL cancer ,ORAL hygiene ,ALARMS ,AWARENESS ,CANCER prevention ,SYMPTOMS ,PRIMARY audience - Abstract
Background: An early diagnosis depends greatly on patient awareness. Thus, the aim of this study was to investigate general awareness of oral cancer and knowledge about its risk factors, signs and symptoms. Material and methods: Cross-sectional population-based survey of randomly selected respondents conducted from March 1, 2015 to 30 June 2016. Results: A total of 5,727 people entered the survey (response rate: 53%). When asked what cancers participants had heard about, 20.3% mentioned oral cancer. Regarding risk factors, tobacco was mentioned by 55.3% of the sample (n=3,169), followed by alcohol (12.5%; n=708), poor oral hygiene (10.8%; n=618), diet (6.5%; n=377), and genetics (4.5%; n=248). Conclusions: General population has low awareness of oral cancer with poor knowledge of risk factors and main alarm signs. In addition, individuals in the risk group scored lower values in the main variables analysed; even those highly educated showed insufficient awareness and knowledge of oral cancer. In these circumstances, there is clear need for educational interventions tailored to the target audience and aimed at increasing knowledge and awareness of oral cancer to promote primary prevention of oral cancer and minimising the time interval of patients with symptomatic oral cancer in their path to treatment. [ABSTRACT FROM AUTHOR]
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- 2021
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26. Regular dental attendance and periodontal health knowledge: A cross‐sectional survey.
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Varela‐Centelles, Pablo, Diz‐Iglesias, Pedro, Estany‐Gestal, Ana, Blanco‐Hortas, Andrés, Bugarín‐González, Rosendo, and Seoane‐Romero, Juan M.
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CONFIDENCE intervals , *DENTAL clinics , *DENTAL health education , *DENTIST-patient relationship , *HABIT , *ORAL hygiene , *PATIENT education , *PERIODONTITIS , *QUESTIONNAIRES , *STATISTICAL sampling , *SEX distribution , *SURVEYS , *LOGISTIC regression analysis , *SOCIOECONOMIC factors , *EDUCATIONAL attainment , *CROSS-sectional method , *HEALTH literacy , *ODDS ratio - Abstract
Objectives: To explore dental clinics' performance on periodontal education by comparing knowledge about periodontal health of regular and inconsistent dental attenders. Subjects and Methods: A population‐based study with a cross‐sectional design was performed in Galicia (Northwestern Spain). Participants were randomly selected from 16 different areas and a questionnaire applied face‐to‐face. The survey included items on socio‐demographic features, habits and routines, periodontal status and periodontal health knowledge. Participants were grouped according to the median of overall knowledge, and a logistic regression analysis was performed to explore the relationship between good periodontal knowledge and frequency of dental visits. Results: A total of 8,206 individuals were invited to enter the study, and 3,553 of them accepted the invitation (43.3%). Most participants (59.3%; n = 1,945) fit within the regular dental attenders' group. Younger women holding a university degree and visiting their dentist regularly elicited higher knowledge about periodontal health. Regular use of dental services increased the chances of being in the higher knowledge group (OR: 1.67; 95% CI: 1.40–2.00). Conclusions: Reported regular dental attendance is related to periodontal health knowledge. Specific interventions for promoting tailored patient education on periodontal topics during routine dental visits may have a positive effect on laypersons' knowledge about periodontal health. [ABSTRACT FROM AUTHOR]
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- 2020
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27. Addressing gaps in transversal educational contents in undergraduate dental education. The audio‐visual 'pill of knowledge' approach.
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Vázquez‐Rodríguez, Inés, Rodríguez‐López, Melina, Blanco‐Hortas, Andrés, Da Silva‐Domínguez, José Luis, Mora‐Bermúdez, María Jesús, Varela‐Centelles, Pablo, and Santana‐Mora, Urbano
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PILLS ,DENTAL education ,INFORMATION & communication technologies ,KNOWLEDGE gap theory ,LEARNING ,UNDERGRADUATES - Abstract
Introduction: Training on impression disinfection is often limited to brief explanations in the clinic. This investigation assessed knowledge on this topic amongst clinical students in our university, produced a pill of knowledge to suit their needs, and evaluated its impact and acceptance. Material and Methods: A pre‐post study was designed to identify knowledge gaps using an anonymous, voluntary self‐applied questionnaire before and after watching an audio‐visual clip (pill of knowledge). All 136 students in the school were invited to enter the study (estimated sample size: 116). Results: Participants: 109 (26.6% in 3rd year; 37.6% in 4th year and 39.4% in 5th year). Participation dropped 10.29% (n = 95) in the post‐intervention survey. Knowledge improvement was higher for those impression materials included in the pill. Most students (68.4%) reported to know more about impression disinfection after the pill and 70.5% felt more able to achieve correct disinfection. The pill was particularly well received (86.3%). All students would recommend it to their peers, and 93.5% are willing to receive pills on other topics. Discussion: Our results disclosed an important gap in knowledge, which can be filled by a single, brief and concise pill adapted to the intended audience. Once made readily available through digital repositories, it may help solve this problem, given the ubiquitous presence of mobile devices. Conclusions: Our results found pills of knowledge as a useful approach to facilitating undergraduates' learning process. This method, using suitable information and communication technologies, has the potential to improve the performance on certain clinical tasks. [ABSTRACT FROM AUTHOR]
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- 2019
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28. Association between hospital interval and survival in patients with oral cancer: A waiting time paradox.
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Lopez-Cedrún, José Luis, Otero-Rico, Ana, Vázquez-Mahía, Inés, Seoane, Juan, García-Caballero, Lucía, Seoane-Romero, Juan Manuel, and Varela-Centelles, Pablo
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ORAL cancer ,PROGNOSIS ,SQUAMOUS cell carcinoma ,CANCER patients ,HOSPITALS - Abstract
In early diagnosis studies on symptomatic cancer, survival was the most recommended outcome. The magnitude and impact of the patient interval and primary care interval is well-known in oral cancer; however, the hospital interval and its influence on surviving this neoplasia are not well known. To quantify the interval between the first contact with the specialist and the start of treatment for patients with oral cancer and to evaluate whether there was a link between this interval and disease survival. We designed a hospital-based study that included 228 patients diagnosed with oral/oropharyngeal squamous cell carcinoma between 1998 and 2008 at A Coruña University Hospital (Spain) who were followed up until 2016. The data were extracted retrospectively from hospital medical charts. The study interval was defined in the context of the "pathways to treatment" model as the interval from the first specialist visit (start point) to the start of treatment (end point). We calculated the total interval (from first symptom to treatment) to evaluate the relative length of the hospital interval, and we considered the variables age, sex, location, comorbidity and tumour classification stage. Survival time was defined as the interval from the first treatment to death or censoring. The median hospital interval was 20 days, with an interquartile range of 15–29.1 days. The most relevant prognostic variable was the tumour stage (III-IV: Exp. ß = 2.8, p = 0.001). The hospital interval was part of the multivariate model, and its association with mortality showed a V-shaped association, where patients with short hospital intervals (3–18 days) and those with long hospital intervals (26–55 days) had significantly higher mortality than those with medium hospital intervals (19–25 days). The hospital interval represents a relevant interval for the patient's path towards treatment, has prognostic implications and is subject to a severity bias (waiting time paradox) that should be avoided. [ABSTRACT FROM AUTHOR]
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- 2019
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29. On the role of physicians in oral cancer diagnosis
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García-Martín, José M., García-Pola, María J., Varela-Centelles, Pablo, and Seoane-Romero, Juan M.
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- 2020
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30. People would rather see a physician than a dentist when experiencing a long-standing oral ulceration. A population-based study in Spain.
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Varela-Centelles, Pablo, Seoane, Juan, Ulloa-Morales, Yaima, Estany-Gestal, Ana, Blanco-Hortas, Andrés, García-Pola, María J., and Seoane-Romero, Juan M.
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MOUTH ulcers ,PHYSICIANS ,DENTISTS ,COMPULSORY education ,ORAL cancer ,PEDESTRIANS - Abstract
Background: Primary care physicians have been reported to be the first choice for patients with oral ulcerations. This study investigates the health-seeking behaviour of lay public in Galicia (North-western Spain) if experiencing a long-standing oral ulceration. Material and Methods: Cross-sectional population-based survey of randomly selected respondents conducted from March 1, 2015 to 30 June 2016. Results: A total of 5,727 pedestrians entered the study (response rate: 53%), mostly in the 45-64 age group (30.2%; n=1,728), 47.7% of them (n=2,729) were males. Most participants (42.1%; n=2,411) reported to visit their dentist once a year and had secondary or compulsory education as their highest educational achievement (28.18%, n=1,614; 28%, n=1,600 respectively). When questioned what they would do if they had a wound/ulceration lasting longer than 3 weeks, most participants answered they would go to see their primary care physician (62.8%; n=3,597) and less than one quarter of the sample (23.8%; n=1,371) would seek consultation with their dentist. Conclusions: General Galician population would seek professional consultation about a long-standing oral ulceration, relying mostly on primary care physicians. Those neglecting these lesions are elderly, less-schooled people and unaware of oral cancer. [ABSTRACT FROM AUTHOR]
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- 2020
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31. Periodontal awareness and what it actually means: A cross‐sectional study.
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Varela‐Centelles, Pablo, Diz‐Iglesias, Pedro, Estany‐Gestal, Ana, Blanco‐Hortas, Andrés, Bugarín‐González, Rosendo, Seoane‐Romero, Juan M., and Blanco, Juan
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RISK factors of periodontal disease , *DENTAL care , *ORAL hygiene , *PERIODONTAL disease , *QUESTIONNAIRES , *STATISTICAL sampling , *HEALTH self-care , *CROSS-sectional method , *HEALTH literacy , *SYMPTOMS - Abstract
Objectives: To assess periodontal awareness among laypersons, to characterize the very aware of periodontitis and to disclose whether high awareness implies sufficient periodontal knowledge. Subjects and methods: Cross‐sectional study on laypersons randomly selected by quota sampling from March 2015 to June 2016. The questionnaire of periodontal awareness included aspects of aetiology, risk factors, signs and symptoms, related risks, prevention, treatment and related attitudes. It was applied by 12 interviewers in the community in each four province capitals, in a sort of pathfinder survey method. Results: A 43.3% response rate was obtained, and 3,553 people entered the study. "Very aware": 19.4%. "Aware": 42.7%. "Not aware": 37.9%. Age, oral self‐care and educational achievements characterized those "very aware." Any additional degree beyond compulsory education halves the chances for being "not periodontally aware." Very aware people likely to have periodontitis were elder, less educated, with a smoking history and less knowledge of the disease. Gaps of knowledge among the "very aware" were identified in all aspects except for "prevention" and "treatment.". Conclusions: Very periodontally aware people were in their late 40–60 s, followed sound oral care routines and held a degree but elicited insufficient knowledge about aetiology, signs‐symptoms, related risks or periodontal risk factors. [ABSTRACT FROM AUTHOR]
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- 2019
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32. Disparities between English and Spanish in readability of online endodontic information for laypeople.
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Miguéns-Vila, Ramón, Ledesma-Ludi, Yanina, Rodríguez-Lozano, Francisco, Varela-Centelles, Pablo, Seoane-Romero, Juan M., and Castelo-Baz, Pablo
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CONFIDENCE intervals ,ENDODONTICS ,ENDODONTISTS ,HEALTH ,INTERNET ,LANGUAGE & languages ,READABILITY (Literary style) ,INFORMATION resources - Abstract
Background. In this study, the authors assessed the readability of online endodontic information in English and Spanish. Methods. The authors performed a systematic search in Google in May 2016. Search queries were "root canal treatment" and "¿Qué es una endodoncia?" without limits or filters. The authors assessed English readability by using Flesch-Kincaid Reading Grade Level, Flesch Reading Ease Score, Gunning Fog Index, Coleman-Liau index, automated readability index, and Simple Measure of Gobbledygook (SMOG) index. The authors calculated readability for Spanish by using the Fernández-Huerta index and INFLESZ (Ines-Barrio). Results. The authors assessed the first 100 consecutive sites identified with each search strategy and selected 117 sites. Readability scores for English-language sites were in the category of normal to read, easily understood by 13- through 15-year-old students (Flesch Reading Ease Score, 63, interquartile range (IQR) [53.9-66.2]; Gunning Fog Index, 10.4, IQR [8.8-12]; Coleman-Liau index, 12.5, IQR [U.6-13.3]; and automated readability index, 8.6, IQR [6.7-9.8]). SMOG results led to the estimation that only 7 years of education would be needed to understand these contents (SMOG, 7.6, IQR [6.5-8.8]). Spanish-language sites had a readability index normal for an adult, equivalent to a seventh or eighth school year (Fernandez-Huerta, 62.3, IQR [59.7-66.6]; INFLESZ, 57.5, IQR [55.1-62.1]). The authors found that 36.6% of English-language sites had some degree of difficulty for readers to understand their contents, whereas 23% of Spanish-language sites had some degree of difficulty (14.46; 95% confidence interval, -3.16 to 30.08). Conclusions. Spanish- and English-language electronic health information about endodontic treatment is acceptable to read, but--particularly for English-language sites--there is an important proportion of sites scoring difficulty levels well above the recommendations. Practical Implications. The internet is a useful tool for communicating with patients, but available endodontic information is difficult for laypeople to understand. Endodontists should produce relevant materials in plain language to overcome this problem. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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33. On the studies of time periods in head and neck cancer diagnosis and treatment
- Author
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Varela-Centelles, Pablo, García-Martín, José M., and Seoane-Romero, Juan
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- 2018
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34. Oral mucosal peeling related to dentifrices and mouthwashes: A systematic review.
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Pérez-López, Daniel, Varela-Centelles, Pablo, García-Pola, María J., Castelo-Baz, Pablo, García-Caballero, Lucía, and Seoane-Romero, Juan M.
- Subjects
ORAL hygiene products ,DENTIFRICES ,META-analysis ,MOUTHWASHES ,ORAL mucosa - Abstract
Background: The aim of this systematic review was to summarise the clinical information available about oral mucosal peeling (OMP) and to explore its aetiopathogenic association with dentifrices and mouthwashes. Material and Methods: PICOS outline: Population: subjects diagnosed clinically and/or pathologically. Intervention: exposition to oral hygiene products. Comparisons: patients using products at different concentrations. Outcomes: clinicopathological outcomes (primary) and oral epithelial desquamation (secondary) after use. Study design: any. Exclusion criteria: reports on secondary or unpublished data, in vitro studies. Data were independently extracted by two reviewers. Results: Fifteen reports were selected from 410 identified. Descriptive studies mainly showed low bias risk, experimental studies mostly an "unclear risk". Dentifrices or mouthwashes were linked to OMP, with an unknown origin in 5 subjects. Sodium lauryl-sulphate (SLS) was behind this disorder in 21 subjects, tartar-control dentifrices in 2, and flavouring agents in 1 case. Desquamation extension was linked to SLS concentration. Most cases were painless, leaving normal mucosa after desquamation. Tartar-control dentifrices caused ulcerations more frequently. Conclusions: OMP management should consider differential diagnosis with oral desquamative lesions, particularly desquamative gingivitis, with a guided clinical interview together with pathological confirmation while discouraging the use of the product responsible for OMP. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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35. Timing of oral Cancer Diagnosis : Implications For Prognosis and Survival
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Varela Centelles, Pablo
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Medical / Oncology - Abstract
Timing of Oral Cancer Diagnosis: Implications for Prognosis and Survival
- Published
- 2012
36. Periodontitis Awareness Amongst the General Public: A Critical Systematic Review to Identify Gaps of Knowledge.
- Author
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Varela‐Centelles, Pablo, Diz‐Iglesias, Pedro, Estany‐Gestal, Ana, Seoane‐Romero, Juan M., Bugarín‐González, Rosendo, and Seoane, Juan
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HEALTH literacy ,PERIODONTITIS ,SYSTEMATIC reviews ,PERIODONTAL disease ,PUBLIC health ,DATA analysis ,HEALTH attitudes ,ETIOLOGY of diseases - Abstract
Background: Poor awareness of periodontal diseases and their consequences has been reported as the most frequent reason for periodontal treatment failure on a community basis. This study aims to identify the most relevant gaps of knowledge about periodontal diseases among the general public and to disclose whether these gaps are culturally consistent.Methods: Systematic searches were conducted of the EMBASE, PubMed, and SciELO databases (1998 to November 2014). The search strategy was "periodontitis OR periodontal disease" and "knowledge OR awareness" as keywords and free text. Papers were included if they reported on community-based, quantitative studies undertaken on adult individuals.Results: A total of 2,330 references were identified (1,567 single papers), and six papers were finally selected. Raw data were grouped into nine dimensions of periodontal knowledge: 1) awareness; 2) etiology; 3) associated risks; 4) signs and symptoms; 5) risk factors; 6) treatment; 7) general knowledge; 8) prevention; and 9) attitudes. This classification recognized disease awareness (80%), etiology (75%), and periodontal-related risks (71.43%) as the most important knowledge deficits among the general public. These findings were confirmed by weighted data analysis.Conclusions: The number of available community-based investigations on periodontal knowledge is scarce and restricted to areas with a very high level of human development. Gaps of knowledge exist in every geographic area, with the most relevant issues of low awareness and poor knowledge about the etiology of periodontal diseases and their relation with systemic disorders. These results highlight the need for local, community-based investigations about periodontal knowledge and barriers hampering early diagnosis, as well as for adequate educational interventions focused on these issues. [ABSTRACT FROM AUTHOR]- Published
- 2016
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37. Coronavirus confinement: A chance to learn on oral cancer—The Spanish experience.
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Varela‐Centelles, Pablo, Lopez‐Jornet, Pía, Gonzalez‐Mourelle, Alicia, and Seoane, Juan
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- *
MOUTH tumors , *QUARANTINE , *HUMAN services programs , *SOCIAL distancing , *STAY-at-home orders , *COVID-19 pandemic - Abstract
The article focuses on chance to learn on oral cancer on Spanish experience. Topics include the most important preventive actions implemented so far to contain the virus have been social distancing and barrier and hygiene measures, and the combination of these three factors resulted in dentists treating only medical and dental emergencies has selected under rigorous ethical and technical criteria.
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- 2021
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38. Pseudoepitheliomatous hyperplasia after diode laser oral surgery. An experimental study.
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Seoane, Juan, González-Mosquera, Antonio, García-Martín, José-Manuel, García-Caballero, Lucía, Seoane-Romero, Juan-Manuel, and Varela-Centelles, Pablo
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HYPERPLASIA treatment ,ORAL surgery ,SEMICONDUCTOR lasers ,PRECANCEROUS conditions ,TREATMENT of oral cancer ,LABORATORY rats ,CANCER treatment ,THERAPEUTICS - Abstract
Background: to examine the process of epithelial reparation in a surgical wound caused by diode laser. Material and Methods: An experimental study with 27 Sprage-Dawley rats was undertaken. The animals were randomly allocated to two experimental groups, whose individuals underwent glossectomy by means of a diode laser at different wattages, and a control group treated using a number 15 scalpel blade. The animals were slaughtered at the 2nd, 7th, and 14th day after glossectomy. The specimens were independently studied by two pathologists (blinded for the specimens' group). Results: at the 7th day, re-epithelisation was slightly faster for the control group (conventional scalpel) (p=0.011). At the 14th day, complete re-epithelization was observed for all groups. The experimental groups displayed a pseudoepitheliomatous hyperplasia. Conclusions: it is concluded that, considering the limitations of this kind of experimental studies, early re-epithelisation occurs slightly faster when a conventional scalpel is used for incision, although re-epithelisation is completed in two weeks no matter the instrument used. In addition, pseudoepitheliomatous hyperplasia is a potential event after oral mucosa surgery with diode laser. Knowledge about this phenomenon (not previously described) may prevent diagnostic mistakes and inadequate treatment approaches, particularly when dealing with potentially malignant oral lesions. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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39. Available web-based teaching resources for health care professionals on screening for oral cancer.
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Varela-Centelles, Pablo, Insua, Angel, Seoane-Romero, Juan M., Warnakulasuriya, Saman, Rapidis, Alexander, Diz, Pedro, and Seoane, Juan
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HOSPITAL medical staff ,ONLINE education ,ORAL cancer diagnosis ,MEDICAL screening ,TEACHING methods ,EDUCATIONAL technology ,EDUCATION - Abstract
Objectives: To identify websites with adequate information on oral cancer screening for healthcare professionals (HCPs) and to assess both their quality and contents. Study Design: Websites were identified using Google and HON medical professional search engines using the terms "screening for oral cancer". The first 100 sites retrieved by each engine were analysed using the DISCERN questionnaire (reliability), the V instrument (contents on oral cancer) and further by the Flesch-Kinkaid Reading Grade Level and the Flesch Reading Ease (readability). Results: The overall rating showed minimal shortcomings in the quality of the information in the websites. The coverage and correctness of information on "visual examination" was rated as fair/good, whereas updating of contents resulted very variable (eg: 81% for visual examination and 18.2% for molecular biomarkers). These results permitted to rank the websites housing relevant information for oral cancer. Top ranking websites were affiliated to the Oral Cancer Foundation (USA), WHO Collaborating Centre for oral cancer (UK) whose webpage is entitled "Oral Cancer Education and Research", and the Clinical Guidelines maintained by the British Columbia Cancer Agency (Canada) and the British Dental Association (UK) respectively. Conclusions: There are web-based, HCP-addressed, resources on screening for oral cancer housing heterogeneous information both in quality and contents. The use of specific evaluation tools permits the selection of reliable websites on this topic with a potential to improve the existing educational gaps among HCPs. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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40. Continuing Education in Oral Cancer Prevention for Dentists in Spain.
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Seoane, Juan, Varela-Centelles, Pablo, Tomás, Inmaculada, Seoane-Romero, Juan, Diz, Pedro, and Takkouche, Bahi
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DISTANCE education ,DENTISTS ,ORAL medicine ,CONTINUING education ,STOMATOLOGISTS ,TREATMENT of oral cancer - Abstract
Continuing education (CE) can have a large impact on dentists' oral cancer attitudes, knowledge, and behavior. Reading scientific journals is a key component of CE. The objective of this study was to assess preventive and clinical attitudes of the participants in an educational intervention on oral cancer in Spain based on scientific journals. Members of the Spanish Board of Dentists and Stomatologists participated in an online, cross-sectional study, using an anonymous, self-administered questionnaire. There were 791 general dental practitioners (GDPs) invited to participate in the study. The large majority reported that they deliver tobacco-cessation counseling (93.6 percent) as well as advice on alcohol consumption (66.6 percent), but advice on vegetable intake was less frequently provided (42.4 percent). Alcohol intake advice, routine mucosa exploration, and biopsy perfomiance on lesions suspicious of malignancy are preventive attitudes related to training. Compared with those who did not benefit from CE courses or did so only once, the GDPs who took four or more CE courses showed a doubling in the odds of giving alcohol advice to their patients and a tenfold increased odds of performing mucosa check on a routine basis; they were 3.5 times as likely to take biopsies of suspicious lesions. A longer experience as a GDP did not increase the probability of adopting preventive attitudes. In addition to presenting the results of this study, the article also discusses the general usefulness of other preventive measures in oral cancer. [ABSTRACT FROM AUTHOR]
- Published
- 2012
41. Reply by the Authors
- Author
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Seoane, Juan, Varela-Centelles, Pablo, Tomás, Inmaculada, Vázquez-Mahía, Inés, García, Augusto Álvarez, and López-Cendrún, José Luis
- Published
- 2012
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42. Lamb Ex Vivo Model for Training in Maxillary Sinus Floor Elevation Surgery: A Comparative Study With Human Standards.
- Author
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López-Niño, Javier, García-Caballero, Lucía, González-Mosquera, Antonio, Seoane-Romero, Juan, Varela-Centelles, Pablo, and Seoane, Juan
- Subjects
DENTAL implants ,ARTIFICIAL implants ,DENTURES ,MAXILLARY sinus ,SURGERY - Abstract
Background: Many models have been suggested for surgical training in sinus floor elevation (SFE), but information on key features that provide feedback to the trainee is scarce. The aim of this study is to compare the thickness of the lateral wall of the maxillary sinus (TLWMS) and the thickness of the Schneiderian membrane (TSM) between an animal model and the human standard. Methods: The observational study used 20 fresh lamb heads. Cone-beam computed tomography (CT) was performed for recording the following: TLWMS, sinus lateral floor width, distance from the lateral border of the anteroposterior bone crest to the sinus wall, and height of lateral maxillary sinus. Thirty human radiologic exploration cone-beam CTs were used for comparisons. The sinus membrane thickness was measured at three points per section and compared to those of 10 formalin-preserved human membranes. Results: TLWMS in the animal model scored 2.25 ± 0.3 mm and was thicker than that of humans with subsinusal edentulism (Xi - Xj = 0.3; 95% confidence interval = 0.1 to 0.4), although this difference was not considered clinically relevant. The average thickness of the sinus membrane was 485.5 ± 137.1 µm with no significant differences between sides (P = 0.12) or between the thickness of human and lamb Schneiderian membranes. Conclusions: The model based on lambs is potentially useful for training in SFE techniques because of the similarities in the TLWMS and particularly the TSM. Additional studies are needed to validate this model within a teaching environment. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
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43. Gingival Mucinous Adenocarcinoma of a Minor Salivary Gland.
- Author
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Seoane, Juan, Varela-Centelles, Pablo, López-Niño, Javier, Vázquez, Inés, Abdulkader, Ihab, and Garcia-Caballero, Tomás
- Subjects
ADENOCARCINOMA ,GINGIVAL diseases ,TUMORS ,ORAL cancer ,HYPERPLASIA ,PSORIASIS - Abstract
Background: A 47-year-old male non-smoker with a history of psoriasis sought a consultation because of a painless, hard-on-palpation, 1-cm exophytic lesion with a smooth and speckled surface located on the hard palate adjacent to tooth #12. The radiologic examination revealed no bone destruction. The lesion was clinically diagnosed as a fibrous hyperplasia or chronic pyogenic granuloma. Methods: The lesion was surgically removed, fixed in 10% neutral buffered formalin for 24 hours, and, following common practice, embedded in paraffin. Sections, 4 µm thick, were stained with hematoxylin and eosin, periodic acid-Schiff, and alcian blue, pH 2.5. An immunohistochemical study was also performed. Results: A definitive diagnosis of a mucinous adenocarcinoma (MAC), a very rare, high-grade malignancy tumor that more frequently appears in the elderly, was made. With the definitive diagnosis of an MAC of the palate, the upper-left premolars were extracted using a box osteotomy, and the surgical wound was reconstructed with a Bichat fat-pad flap. After a 6-month follow-up, no recurrence or cervical metastases were identified. Conclusions: An MAC of a minor salivary gland may arise as a gingival exophytic lesion with a clinical appearance similar to a pyogenic granuloma. The existence of a light speckled pattern on the surface of the lesion indicates that an incisional biopsy is needed before surgical treatment to make possible a definitive diagnosis. To avoid delays in diagnosis and erroneous clinical approaches to exophytic gingival lesions, periodontists and practitioners should routinely perform a pathologic analysis to confirm the diagnosis when dealing with these kinds of lesions. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
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44. Impact of the Presenting Symptom on Time Intervals and Diagnostic Routes of Patients with Symptomatic Oral Cancer.
- Author
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Varela-Centelles, Pablo Ignacio, López, Daniel Pérez, López-Cedrún, José Luis, García-Rozado, Álvaro, Baz, Pablo Castelo, Romero-Méndez, Amparo, and Seoane, Juan
- Subjects
- *
DELAYED diagnosis , *MOUTH tumors , *CONFIDENCE intervals , *PROFESSIONS , *TIME , *CROSS-sectional method , *DENTISTS , *PRIMARY health care , *CONCEPTUAL structures , *MEDICAL referrals , *DESCRIPTIVE statistics , *EARLY diagnosis , *SYMPTOMS - Abstract
Simple Summary: Information about the relative length of patient stays, primary care, and prereferral intervals (from symptom onset to specialist referral) is very scarce, and how the presenting symptoms influence these intervals and referral routes remains unknown. This study assesses the impact of presenting symptoms on time intervals, number of visits at the primary care level, and referral pattern of patients with symptomatic oral cancer. This approach will allow targets to be identified for future interventions and the optimization of the treatment pathway for symptomatic oral cancer patients. This investigation was aimed at determining the time intervals from the presenting symptoms until the beginning of oral cancer treatment and their relative contribution to the total time, and to assess the impact of the presenting symptom on diagnostic timelines and patient referral routes. A cross-sectional, ambispective study was designed to investigate symptomatic incident cases. The Aarhus statement was used as a conceptual framework. Strategies for minimizing potential recall biases were implemented. A sample of 181 patients was recruited (power: 99.5%; α = 0.05). The patient interval reached 58.2 days (95% CI, 40.3–76.2), which accounted for 74% of the whole prereferral interval and for more than one third of the total time interval. The presenting symptom (trigger for consultation) influenced both the number of primary care consultations and the length of time to diagnosis. General dental practitioners generated longer intervals to diagnosis (p < 0.005) and needed more consultations before referring a patient (RR = 0.76; 95% CI, 0.61–0.93), than general medical practitioners. The current study identifies the patient as the main target for interventions to improve awareness and reinforces the need for increased alertness amongst healthcare professionals about presenting symptoms of oral cancer and to diminish the number of prereferral consultations in order to optimize the primary care interval. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
45. Gingival Squamous Cell Carcinoma: Diagnostic Delay or Rapid Invasion?
- Author
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Seoane, Juan, Varela-Centelles, Pablo I., Walsh, Trevor F., Lopez-Cedrun, Jose L., and Vazquez, Ines
- Subjects
SQUAMOUS cell carcinoma ,GINGIVAL diseases ,CANCER diagnosis ,DIAGNOSTIC errors ,HISTOPATHOLOGY ,MEDICAL referrals - Abstract
Background: The similarity between gingival squamous cell carcinoma (GSCC) and more common periodontal lesions may lead to a delay in diagnosis or misdiagnosis. Neoplastic lesions of gingival tissues are frequently diagnosed at an advanced stage. Methods: To assess the relative time from when patients first become aware of the problem to histopathologic diagnosis (total diagnostic time), 59 consecutive oral cancer cases were examined in this study. The following variables were considered: age, gender, smoking habits, tumor stage at diagnosis, and total diagnostic time. The median of the patients' total diagnostic time (1.5 months) was used as a cutoff point to distinguish between delayed and non-delayed cases. Analysis of the variables was undertaken using the Student t test and χ² test, with a 95% confidence interval (Cl). Results: The total diagnostic time was <1.5 months for 75% of gingival carcinomas, 50% of tongue carcinomas, and 78% of floor-of-the-mouth carcinomas. It was >1.5 months for 25% of gingival carcinomas, 50% of tongue carcinomas, and 21% of floor-of-the-mouth carcinomas. No significant differences in time before diagnosis were found when gingival cancers were compared to other oral tumors (χ² = 0.21; 95% Cl =-0.40 to 0.26). However, by the time of diagnosis, gingival cancers had invaded adjacent structures more frequently than other oral cancers (χ² = 13.51; 95% Cl = 0.18 to 0.85). Conclusions: The gingival location of oral squamous cell carcinoma (OSCC) was associated with advanced stages at the time of diagnosis, due to early invasion of contiguous bone tissue (T4-primary tumor). This would indicate that even earlier referral and diagnosis are necessary. [ABSTRACT FROM AUTHOR]
- Published
- 2006
- Full Text
- View/download PDF
46. Time-to-Treatment in Oral Cancer: Causes and Implications for Survival.
- Author
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Saka-Herrán, Constanza, Jané-Salas, Enric, Mari-Roig, Antoni, Estrugo-Devesa, Albert, López-López, José, and Varela-Centelles, Pablo
- Subjects
SURVIVAL ,MOUTH tumors ,TIME ,PROGNOSIS ,EARLY detection of cancer ,TREATMENT delay (Medicine) ,COST analysis ,QUALITY of life - Abstract
Simple Summary: Stage of the disease at diagnosis has been recognized as one of the most important prognostic markers for oral cancer. Unfortunately, still two thirds of patients are diagnosed at an advanced stage of disease with a 5-year survival rate of 50% or less. Although the detection of oral cancer at an early stage is the most effective means to improve survival and reduce morbidity, in the past years, there has been little change in the diagnosis of oral cancer at early stages, which is believed to be a result of delays in diagnosis and treatment of oral cancer, among other independent factors. Following the Aarhus statement, developed in effort to standardize the design, methods and reporting of studies concerning time-intervals in early diagnosis research, the review assessed the causes that influence the patient, diagnosis and pre-treatment intervals in the pathway of time-to-treatment in oral cancer and its impact on survival. The purpose of this review was to identify and describe the causes that influence the time-intervals in the pathway of diagnosis and treatment of oral cancer and to assess its impact on prognosis and survival. The review was structured according to the recommendations of the Aarhus statement, considering original data from individual studies and systematic reviews that reported outcomes related to the patient, diagnostic and pre-treatment intervals. The patient interval is the major contributor to the total time-interval. Unawareness of signs and/or symptoms, denial and lack of knowledge about oral cancer are the major contributors to the process of seeking medical attention. The diagnostic interval is influenced by tumor factors, delays in referral due to higher number of consultations and previous treatment with different medicines or dental procedures and by professional factors such as experience and lack of knowledge related to the disease and diagnostic procedures. Patients with advanced stage disease, primary treatment with radiotherapy, treatment at an academic facility and transitions in care are associated with prolonged pre-treatment intervals. An emerging body of evidence supports the impact of prolonged pre-treatment and treatment intervals with poorer survival from oral cancer. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
47. A punch technique for gingival incisional biopsy.
- Author
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Seoane, Juan, Varela‐Centelles, Pablo Ignacio, Limeres‐Posse, Jacobo, and Seoane‐Romero, Juan Manuel
- Abstract
The article presents information on the gingival incisional biopsy, which is one of the most common techniques to treat the lesions in the gingiva. It informs that the gingiva is a common site for reactive, non-neoplastic, and neoplastic lesions with unspecific clinical features. It further informs that the gingival biopsies may be also useful in the diagnosis of amyloidosis and syndromic entities.
- Published
- 2013
- Full Text
- View/download PDF
48. Powered rotary scalpel for biopsies in difficult areas of the oral cavity.
- Author
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Seoane, Juan, Varela-Centelles, Pablo, Diz-Dios, Pedro, and Limeres, Jacobo
- Published
- 2006
- Full Text
- View/download PDF
49. Use of Chalazion Forceps to Ease Biopsy of Minor Salivary Glands.
- Author
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Seoane, Juan, Varela-Centelles, Pablo I., Diz-Dios, Pedro, and Romero, Maria
- Published
- 2000
- Full Text
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50. Letter to the Editor: Re: A Stab-and-Roll Biopsy Technique to Maintain Gingival Epithelium for Desquamative Gingivitis.
- Author
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Varela-Centelles, Pablo, Seoane-Romero, Juan M, Liñares, Antonio, and Seoane, Juan
- Published
- 2015
- Full Text
- View/download PDF
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