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Yüzyıllar boyu yarı göçebe bir hayat şeklini benimseyen Türk halkları, yaşayışlarının bir yansıması olarak tabiatla sürekli iç içe olmuşlardır. Bu durum Türk halklarının tabii olarak hayvanlarla yakından ilgili olmasına da sebep olmuştur. Hayvanlar gerek besin kaynağı olmaları nedeniyle gerek araç-gereç ve giyinme aracı olarak kullanılmalarıyla, gerekse sosyal hayat içinde bir eğlence aracı, dost, yol gösterici olmalarıyla Türklerin vazgeçilmez bir parçası olmuşlardır. İnsanoğlunun varoluşundan günümüze tabiat ile ilgili sesler, hareketler, olaylar taklit konusu olmuş; insanlar daima duygu, düşünce ve hareketlerini anlatırken tabiattaki değişiklikleri benzetme unsuru olarak kullanma ihtiyacı hissetmişlerdir. İnsanların fiziksel ve karakteristik özelliklerini betimlemek için doğadaki olaylar ve sesler nasıl örnek alındıysa, doğanın en önemli parçası olan hayvanların da sesleri ve hareketleri benzetme aracı olarak kullanılmıştır. Halen yarı göçebe bir hayat tarzını devam ettiren Kırgızlarda, hayvanların insanları betimlemek için benzetme aracı olarak kullanılması daha da ileri seviyededir. Türk halkları arasında güçlü bir sözlü geleneğe sahip olan Kırgızlar, dünyanın en uzun destanı olan Manas Destanı dışında çok sayıda destana sahiptir. Bu destanlar Kırgızların kültürünü, tarihini, yaşam tarzlarını yansıtan önemli sözlü miraslardır. Yapılan bu çalışmada Kırgız kahramanlık destanlarından biri olan Eşimkul ve Zuura Destanı’nda adı geçen hayvanların genel özellikleri belirtilerek bu hayvanların hangi özellikleri bakımından benzetme unsuru olarak kullanıldığı destandan örneklerle verilecektir. Kahramanlık destanlarında hayvanların benzetme unsuru olarak daha sık kullanılmasının sebebi destana konu olan kahramanın olumlu özelliklerini; düşmanın ise olumsuz özelliklerini daha etkili bir şekilde ifade etmektir.Çalışmada Türk Dil Kurumu tarafından yürütülen Türk Dünyası Destanlarının Tespiti, Türkiye Türkçesine Aktarılması ve Yayımlanması Projesi kapsamında Cumagül Naruzbayev anlatımıyla Fatma Çelebi tarafından hazırlanan bir eser olan Kırgız Destanları V- Eşimkul Menen Zuura Destanı taranarak çalışmaya kaynaklık eden veriler elde edilmiştir.

The war in Ukraine has had an extensive impact upon societies not directly involved in the military fighting. Traditional and social media has been filled with references to the war and discussions concerning how individuals as well as society as a whole would cope if war were to erupt in Sweden. In this context, an often overlooked issue is the relationship between humans and animals. This article discusses challenges to the total defence system, brought on by the norms of the 2020s, concerning the social relationship between humans and animals. It presents a number of areas wherein the relation between humans and animals is likely to raise questions and invoke conflict with existing regulations of the total defence: views of security, laws and regulations for wartime and crisis situations, and the development of social relations between humans and animals. Finally, some ideas are presented regarding how a total defence including animals could be materialized, and which changes such ideas would pose to the present total defence. [ABSTRACT FROM AUTHOR]

This article is a review of Frans de Waal's book Mama's Lust Hugs. Animal Emotions and what They Tell Us about Ourselves, which was released in Polnad in 2019. The book deals with the problem of animal emotionality. One of the conclusions reached by the author and which was emphasized in the review is the thesis that there is no such thing as unique human emotions that animals would not have. Emotions are universal; they are shared both by humans and animals. The review noted that although the book is interesting, it is not new in terms of content, because it deals with issues that de Waal wrote about many times in his earlier publications. On the other hand, thanks to the collection and inclusion in one book of the issues related to emotionality in animals, the publication can be a good starting point for reflection not only on animals (their emotionality and rights), but also on humans and their place in the world. It puts the reader in facing the question of human nature. For this reason, what has been tried to show in the review, Frans de Waal's book is a good example of how scientific issues lead to philosophical reflections.

Most of the nomads of East Azerbaijan province belong to the tribes of Arasbaran and Shahsevan, nine independent tribes in the Yaylak period, and seven independent tribes in the Qishlaq period. Shahsevan nomads are composed of different tribes, such as Ajirlu, Moghanlu, Giglu, Qaralar Meshgini etc. Verneh, as a type of carpet, Maffrash or means of carrying household furniture, were mainly woven by nomads and some villagers in the settlement of Shahsevan nomads in Azerbaijan and some surrounding areas, such as Pars Abad, Germi and Meshgin Shahr counties of Ardabil province, and Ahar and Kaleybar counties of East Azerbaijan province. This handicraft has both the simplicity of the rug (Kilim) style and the elegance and beauty of the carpet. The lack of sufficient information in this field has led to a close study of some of these motifs related to Verneh. Therefore, one of the most important objectives of the research is to introduce motifs, concepts and animal symbols hidden in Verneh, in order to expand knowledge about the artistic products of this region and examine the impact of nomadic life conditions on the nature of their products in these areas. The research method is applied in terms of nature and purpose and its findings were first done as field research. Then, the samples from the studies were matched with the general information and eventually examined. The results of this study show that the animal motifs created in verneh tell the truth about the material and social life of weavers and show a valuable collection in their life. Verneh’s paintings and motifs depict the nomadic way of life, the animal-dependent life in direct connection with nature, the adherence to the customs of the ancestors and the beliefs of these people. Animal motifs are a symbol of nomadic life, related to nomadic livestock.

The aim of this article is to provide comparative perspectives on the keeping of animals in sectional title schemes by analysing the conduct rule for the keeping of animals, reptiles, and birds in the provisions of the Sectional Titles Schemes Management Act. This investigation is prompted by the approval of new pet rules by the chief ombud and the provisions of the Community Schemes Ombud Service Act on adjudication orders available for nuisance caused by animals. The Act further allows the body corporate to record a new scheme governance rule or to declare a scheme rule invalid. The topics to be discussed are: the types of animal kept in sectional title schemes; the written approval of the trustees for the keeping of animals which may not be withheld unreasonably; whether the body corporate may adopt a scheme rule containing a blanket prohibition on the keeping of animals in a sectional title scheme; the reasonable conditions which may be attached to trustee approval; the withdrawal of approval if the conditions are breached; the requirements for a rule restricting the keeping of a kind of animals or animals with specific characteristics in a scheme; and the deemed approval for the keeping of guide, hearing, and assistance animals in a sectional title scheme.

Introduction: The brainstem auditory evoked response (BAER) is a diagnostic approach to examine the hearing system of horses objectively. The aim of this BAER examination was the diagnosis of conductive or sensorineural hearing loss or deafness in horses with external otitis, head trauma, headshaking, tinnitus or skittish horses with eye disease. Brainstem dysfunction is induced by intracranial hypotension. BAER was used in horses with colic surgery which had a low arterial blood pressure during general anesthesia. The endoscopic finding of the guttural pouch was the ipsilateral mild to severe hypertrophy of the tympanostylohyoideum in horses with external otitis or head trauma. The otoscopic examination of standing sedated horses was done before BAER. The cartilagineous and osseous part of the external ear canal in horses with external otitis were obstructed with exsudate and tympanic membranes were not visible. Horses with right sided external otitis: right moderate to severe conductive hearing loss (significantly prolonged latencies of I, III, V and interpeak latencies I-III, I-V, III-V; thresholds of hearing levels 60 to 80 dB right); horses with left sided external otitis: left severe conductive hearing loss (no correct identification of BAER peaks, latencies not measurable, 80 dB); horse with left sided head trauma: severe left sided conductive hearing loss (blood in the left external ear canal, no visible tympanic membrane, no correct identification of BAER peaks, latencies not measurable, 80 dB); horses with head shaking: mild sensorineural hearing loss on both sides (on both sides osseous parts II/III with keratin scales of the junction, visible tympanic membranes, significantly prolonged V, I-III, I-V, 40 dB); moderate to severe skittish horses with chronic eye disease (mostly left sided equine recurrent uveitis): moderate sensorineural hearing loss on both sides (normal otoscopical findings, significantly prolonged latencies and interpeak latencies left; I-V, III-V right, 60 dB, pathological involvement in the auditory pathway of the brainstem between the cochlear nucleus and colliculus caudalis); horse with a tinnitus on both sides: mild sensorineural hearing loss on both sides (normal otoscopical findings, prolonged V, I-III, I-V, III-V, 40 dB, pathology of auditory nerve, cochlear nucleus and above the level of this nucleus); American paint horses: sensorineurale deafness on both sides (normal otoscopical findings, absent BAER peaks, isoelectric lines and 80 dB on both sides). The prolonged latencies of I, III and V including interpeak latencies I-III only left and I-V and III-V on both sides in horses with laparotomy during general anesthesia were associated with low arterial blood pressure (62 mmHg, median). These findings could demonstrate a hypotension in the brainstem too. The BAER could be a technical tool during general anesthesia for normalizing the arterial blood pressure and brainstem function to prevent imbalance of body movements after general anesthesia.

The various connective tissues of the body have different functions, which result from their specific structure and composition. The identification of this structure-function relationship is of great importance for various disciplines such as medicine, biology or tissue engineering. Connective tissue consists mainly of an extracellular matrix (ECM) and a limited number of cells. It is extremely adaptable because the activity of the cells remodels the composition and structure of the ECM in order to adapt the mechanical properties (functions) to the new demands (e.g. an increased mechanical stimulus)., (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)

Bite injuries require differentiated treatment due to the deeply inoculated polymicrobial pathogen spectrum, possible concomitant injuries and pronounced soft tissue damage. Dog bites are the most common bite injuries but are less complicated to heal than human and cat bites. The location of the bite greatly depends on the age and the size of the bite victim as well as the type of bite perpetrator. In every case detection of the pathogen should be carried out to provide the best possible adapted treatment in the event of an exacerbation. The primary antibiotic treatment should be empirical with amoxicillin + clavulanic acid or ampicillin + sulbactam and, if necessary, adjusted according to the antibiogram. Depending on the findings, surgical treatment includes excision of the bite canal and a customized wound debridement. It is important to check the vaccination status of those involved and if indicated, to carry out postexposure prophylaxis for tetanus and rabies., (© 2024. The Author(s).)

Uroperitoneum is a rarely documented finding in heifers. More frequently uroperitoneum is described in male youngstock suffering from obstructive urolithiasis, or abscesses of the urachus. This report describes a case of uroperitoneum most likely as a result of a traumatic rupture of the urinary bladder in an 8.5 months old heifer. The animal was presented with a severely dilated abdomen and an undulating wave was evident upon palpation. The heifer exhibited physiologic urination. Additionally, left displacement of the abomasum was evident. In consequence to findings of the ultrasonographic examination and abdominocentesis, diagnostic laparotomy was performed. Urine was evacuated from the abdominal cavity in fractions and the damaged cranial pole of the urinary bladder was excised followed by the suture of the urinary bladder. The abomasum was replaced in its physiologic position and an omentopexy was performed. The heifer was discharged from hospital and was still in the herd 5 years after discharge., Competing Interests: Die Autorinnen erklären, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

Objective: The results of this study describe the relationship between the body condition of dairy cows and selected metabolic parameters during the peri- and post-partum period with special consideration of 3 local dairy cow breed in Upper Bavaria and the Allgau., Material and Methods: Three local dairy cattle breeds (Swiss Brown (BV), Simmental (FL), Holstein Friesian (HF)) were examined on 68 farms in southern Germany for 7 consecutive weeks. In dry cows as well as lactating cows (5.-65. day in milk), following blood parameters were investigated: beta-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA), creatinine, aspartate aminotransferase, gamma-glutamyltransferase, glutamate dehydrogenase, total protein, albumin, creatine kinase. In addition, body condition (body condition score [BCS] and back fat thickness [BFT]) were recorded. Exploratory and descriptive statistics were used for data analysis., Results: Concerning the difference in condition before and after calving, the FL showed the smallest difference in RFD. For FL and BV a trend towards higher BFT values could be seen in first lactating cows. For FL and HF, the NEFA values of the later lactating cows were below those of the first lactating cows. The higher lactating cows of BV and FL had higher BHB values. The correlation between BFT and BCS showed the highest R2 (0.53) in the HF cows. BV and FL were below at 0.42 and 0.37. BCS and BFT could not be predicted by the variables NEFA, BHB and liver enzymes. BHB levels of all 3 breeds increased at weeks 2-4 post-partum. The NEFA values for all 3 breeds increased primarily in the 1st-3rd week p.p. in parallel to when the BFT p.p. decreased. NEFA values were highest when body condition declined and therefore when fat mobilization peaked. In BV and HF, there was a constant increase in GLDH when the p.p. BCS difference was there., Conclusion and Clinical Relevance: Body condition assessment (BCS at herd and animals` level, BFT at animal level) is an important tool for animal health monitoring. Due to the recognizable breed specificity, the dairy herds can be dealt with more explicitly. The aim is to optimally influence the energy balance of the cow during early lactation in order maintain the health of the animal and its organ systems., Competing Interests: Die Autor*innen bestätigen, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

Object and Purpose: Acid-base disorders in dairy herds can be diagnosed by determining urinary net base excretion (NBE). Modifications of this method are the differential NBE (dNBE) with determination of the urinary concentration-independent base-acid ratio (BAR) and the simplified NBE test with reduced urine volume (sNBE). The aim of this study was to compare these methods among themselves and as a pooled test, in their assessment of cow group acid base status as well as to derive recommendations for practical use., Animals, Material, and Methods: The concentrations of NBE, dNBE, and sNBE were measured in urine samples derived from 855 German-Holstein cows in 127 cow groups at different stages of lactation. BAR was then calculated. dNBE and BAR were determined both individually per cow and as a pool of a group. Mixed linear models were used to examine the relationship between the mean of the individual animal values and the pool sample result of a group for these two parameters. In addition, all groups were evaluated with respect to acidotic or alkalotic load based on their single animal results of the respective methods, the mean values formed from them, and the measured pool result. By using the single animal BAR as reference, the sensitivity and specificity of the different methods were calculated., Results: The calculated mean values of the individual measurements of dNBE and BAR differed from the measured value in the pool sample, especially in low and high measurement ranges. In the group assessment, NBE showed the best combined sensitivity and specificity for the detection of acid base disorders. The dNBE pool assay showed satisfactory specificity with respect to acidosis and alkalosis, while the sNBE on an individual animal basis and the BAR determination in the pool showed satisfactory sensitivity with respect to acidosis., Conclusions and Clinical Relevance: It was shown that NBE determined in individual animal samples is well suited for the assessment of acid base status of cow groups and can therefore be recommended for practical use. The determination of dNBE as well as BAR as a pool test is not sufficient for the detection of alkalotic load in cow groups but may help to confirm an existing acidotic load., Competing Interests: Die Autoren erklären, dass keine geschützten, finanziellen, beruflichen oder anderweitigen Interessen an einem Produkt oder einer Firma bestehen, welche die in dieser Veröffentlichung genannten Inhalte oder Meinungen beeinflussen können., (Thieme. All rights reserved.)

An acute, unilateral othematoma was diagnosed in a 9-year-old mixed-breed dog. There was no clinical or anamnestic evidence for the cause of the othematoma. During diagnostic work-up, marked hyperglobulinemia and marked thrombocytopenia were detected. This was a consequence of a multiple myeloma. This is the first case report of a dog with othematoma secondary to coagulopathy associated with multiple myeloma., Competing Interests: Die Autoren haben keine Interessenkonflikte zu deklarieren., (Thieme. All rights reserved.)

In horses, parturition is characterized by the fact that any delays may rapidly result in the death of the foal. Therefore, birth monitoring and the rapid detection of dystocia are of great importance. For this purpose, the differentiation between behavior associated with physiological parturition and activities related to difficult parturition is important. The aim of this publication is to present the physiological behavior of mares during parturition on the basis of a literature review. The behavior of mares in the opening phase of parturition is highly individual. In general, it is characterized by an increase in movement activity. In this phase of parturition, 13 different behaviors have been described (e. g. lying down and standing up, cessation of feed intake, local sweating, frequent defecation and urination). Mares show a more uniform pattern of behavior in the expulsion phase and the following phase of expulsion of the fetal membranes and placenta. More than 95% of mares give birth in the lateral position. A mare usually remains in recumbency for several minutes following the expulsion of the fetus. Immediately after standing up, the mare begins to intensely interact with the foal. The expulsion of the fetal membranes and the placenta usually takes place in a standing position. From a clinical point of view, it is important to give consideration to the difficulty in recognizing the opening phase of parturition due to the mares' individual behavior patterns., Competing Interests: Die Autoren bestätigen, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

A 2-year-old Norwegian Forest cat was presented for evaluation of bilateral purulent nasal discharge and stertorous breathing. A computed tomography (CT) scan of the head revealed an intranasal mass of the left nasal cavity extending behind the tube openings and completely obstructing the nasopharynx. Rhinoscopy confirmed a pinkish, shiny mass. CT scan showed both compartments of the right middle ear filled with abnormal soft tissue attenuating material. There was no change in the bony outline of the middle ear. In the endoscopic examination, after endoscopically assisted tympanocentesis, this material in the accessible dorsolateral compartment proved to be classic polypous tissue in addition to highly viscous glue-like secretions. A secondary otitis media due to a drainage disorder was suspected.Using an endoscopic-interventional approach through the nostril, the nasopharyngeal mass was removed for histopathological examination, in order to restore the nasal airway, and to allow tube drainage. In contrast to cats with classical malignant nasal cavity masses, the cat showed several attachment points of the mass and multiple undulating elevations bilaterally in the nasopharyngeal mucosa.Cytological and histopathological examination identified the mass as a fungal granuloma in the context of a cryptococcus infection only rarely observed in Germany. Molecular genetic analysis confirmed an infection with Cryptococcus neoformans var. grubii .A single intranasal and nasopharyngeal endoscopic debridement resulted in a significant improvement of the clinical signs and a complete healing of the right middle ear (including the tympanic membrane) within 14 days, but not in a complete cure of the disease. The cat was therefore treated with oral itraconazole solution for several weeks.The case report shows that nasal cryptococcosis can also affect cats in Germany. Rhinoscopy reveals a nasopharyngeal mass with multiple attachment points, which is unusual for a neoplasia. In addition to the recommended removal of the mass, oral administration of systemic antimycotics is strongly advised., Competing Interests: Die Autoren bestätigen, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

After birth, an alpaca cria was noticed to exhibit weakness and respiratory distress, particularly when attempting to suckle milk from the dam's udder. Clinical findings indicated the presence of bilateral choanal atresia and the animal was subsequently euthanised. A computed tomography scan and a pathological examination were performed to describe the malformation in detail. Choanal atresia is a common malformation in neonatal South American camelids, surgical treatment is not recommended. This case report provides an overview of the clinical findings as well as the results of imaging and pathologic examinations and may help to raise awareness of this malformation for early recognition., Competing Interests: Die Autoren bestätigen, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

Germany has been considered free of terrestrial rabies since 2008 as a result of intensive vaccination and surveillance efforts but reservoirs of the lyssaviruses EBLV‑1 and EBLV‑2 persist in bat colonies and thus pose a potential risk of infection. We report on a patient who suffered a bat bite in an urban setting in which European bat lyssavirus 1 (EBLV-1) was detected in the euthanized bat. We performed active and passive postexposure prophylaxis (PEP). This case study illustrates the ongoing risk of rabies infection due to close bat contacts in Germany and is intended to sensitize primary care physicians to take such exposure events seriously and to perform a regular PEP including administration of rabies immunoglobulin., (© 2023. The Author(s).)

Introduction: The aim of this retrospective study is to describe and compare conservative and surgical treatment of navicular fractures in horses. An attempt is made to identify critical points that can favorably influence the prognosis of this orthopedic disease. All horses treated for a navicular fracture at the Equine Clinic, Vetsuisse Faculty, University of Zurich between 2005 and 2017 were included in this study. The severity of lameness at initial examination, radiographic assessment, hoof conformation, treatment (conservative or surgical), complications and outcome were determined from the medical records. Conservative and surgical treatment consisted of stable rest, a controlled exercise program and therapeutic orthopedic shoeing. During surgical treatment, fracture reduction was also carried out with a cortical screw. Computer assisted surgery were used in five horses and computer tomography in three horses. Follow-up examinations included clinical and radiographic examinations. The outcome was divided into three categories: 1 = very good; 2 = good; 3 = poor. Twelve horses met the inclusion criteria; Four horses were treated conservatively and eight were treated surgically. After conservative treatment, two horses (50 %) had a very good outcome and two (50 %) had a good outcome. After surgical treatment, four horses (50 %) had a very good outcome and four (50 %) had a poor outcome. Overall, 67 % of horses had a very good or good outcome, although radiographic signs of bone healing was not present in any of these cases. Various complications were identified, such as the fracture of a screw, the fragmentation of the small navicular bone fragment, the development of osteoarthrosis in the coffin joint and progressive podotrochosis. This study shows that the prognosis of navicular fractures is generally cautious and that degenerative changes to the navicular apparatus worsen the prognosis. In the present study, surgical treatment did not improve the prognosis of navicular fractures despite the intrasurgical use of three-dimensional imaging. However, technical advances could reduce the complication rate in the future.

Alpha-gal syndrome (AGS) is a mammalian meat allergy associated with tick bites and specific IgE to the oligosaccharide galactose-α-1,3-galactose (α-gal). Recent studies have shown that 10-20% of AGS patients also react to the dairy proteins. Considering the already described role of the meat lipid fraction in AGS manifestations, the aim of this work has been to investigate whether the milk fat globule proteins (MFGPs) could be involved in AGS. The MFGPs are extracted and their recognition by the IgE of AGS patients is proved through immunoblotting experiments. The identification of the immunoreactive proteins by LC-HRMS analysis allows to demonstrate for the first time that butyrophillin, lactadherin, and xanthine oxidase (XO) are α-gal glycosylated. The role of xanthine oxidase seems to be prevalent since it is highly recognized by both the anti-α-gal antibody and AGS patient sera. The results obtained in this study provide novel insights in the characterization of α-Gal carrying glycoproteins in bovine milk, supporting the possibility that milk, especially in its whole form, may give reactions in AGS patients. Although additional factors are probably associated with the clinical manifestations, the avoidance of milk and milk products should be considered in individuals with AGS showing symptoms related to milk consumption., (© 2024 Wiley‐VCH GmbH.)

Background: Rat bite fever is a rare but potentially fatal bacterial zoonosis. The symptoms can be unspecific, but severe sepsis can be associated with involvement of different organs., Case Report: A 27-year-old homeless man presented with fever, suspected meningitis, acute renal failure, unclear skin lesions as well as joint problems and muscular pain. Bite wounds were not detected. Meningitis could be excluded after lumbar puncture, and there was no evidence of endocarditis as the cause of the skin lesions. After 72 h, growth of Streptobacillus moniliformis in blood cultures was detected. Clinical symptoms were compatible with the diagnosis of rat bite fever. Calculated antibiosis with ampicillin sulbactam and doxycycline led to regression of the symptoms., Conclusion: Rat bite fever poses a diagnostic challenge due unspecific symptoms, diverse differential diagnostic options, and challenging microbiological detection. Patient history is of the utmost importance. Due to the rarity of the disease, this case report is intended to raise awareness., (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)

Introduction: We describe the case of a 58-year-old patient who developed chest pain and an anaphylaktoide reaction after ingestion of contamined fish containing histamin. Histamin intoxication from food poisoning (also known as scombroid intoxication) can be mistaken for an anaphylactic reaction and occasionaly lead to cardiac symptoms, even in patients without atherosclerotic changes. This condition is called Kounis syndrom and has to be recognized as a separate syndrom with specific clinical features., Competing Interests: Es bestehen keine Interessenkonflikte, (© 2024 Aerzteverlag medinfo AG.)

Due to the legal implantation of the 3R principle, the number of laboratory animals decreased significantly over the past 10 years. In this article, the historical development of animal experiments over the last decade will be presented in the context of the current regulations of the Animal Welfare Act. It points out bureaucratic obstacles to the approval of animal experiments, which jeopardize Germany as a research location for both academia and industry. The article presents constructive proposals for solutions. This should be done in accordance with the DFG recommendation to ensure efficient biomedical research while maintaining the highest animal welfare standards., (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)

Introduction: Feeding raw meat is becoming increasingly common among dog owners. This feeding practice can pose a hygienic risk and can lead to health risks for dogs and their owners. Hygienically sound food rations, that are balanced in terms of all nutrients and energy, must be feed to breeding dogs. The aim of this study was to record the influence of raw feeding on the occurrence of mastitis, metritis and the survival of puppies. An online questionnaire was sent to kennel club registered dog breeders in Germany and Switzerland. A total of 531 litters were recorded and evaluated. Mastitis and/or metritis were present in 9,2 % and 2,8 % (n = 49 and n = 15, respectively) of the breeding bitches. 29 % (n = 154) of the breeders reported loss of puppies in the litter. The most common cause were stillbirths (n = 105 litters with 187 stillborn puppies), and/or early mortality (n = 50 litters with 73 puppies that died in the first 48 hours). The occurrence of puppy losses in the litter and/or a higher proportion of puppy losses in the litter was favored by increased body weight of the bitch in larger dog breeds, existing previous illnesses, previously reported gestation or postpartum problems, increasing length of the parturition phase and/or a cesarean section. A higher total number of surviving puppies was associated with increased weight and anamnestic reported health of the bitch and the use of milk powder instead of other milk substitutes. A relationship between raw feeding and the occurrence of mastitis, metritis, the total number of surviving puppies and/or the occurrence or proportion of pup losses in the litter and was not found in this study. However very few breeders in this cohort fed their bitches raw, which in turn was due to the random selection of breeders. Many years of breeding experience and the increasing parity of the bitch had a clearly positive influence on the health of the bitch.

Comparative experimental pathology is a research field at the interface of human and veterinary medicine. It is focused on the comparative study of similarities and differences between spontaneous and experimentally induced diseases in animals (animal models) compared to human diseases. The use of animal models for studying human diseases is an essential component of biomedical research. Interdisciplinary teams with species-specific expertise should collaborate wherever possible and maintain close communication. Mutual openness, cooperation, and willingness to learn form the basis for a fruitful collaboration. Research projects jointly led by or involving both animal and human pathologists make a significant contribution to high-quality biomedical research. Such approaches are promising not only in oncological research, as outlined in this article, but also in other research areas where animal models are regularly used, such as infectiology, neurology, and developmental biology., (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)

This article analyzes the language creation of farm animals in selected novels by Wiesław Myśliwski. The subject of the research are the first three works by the writer Nagi sad, Pałac and Kamień na kamieniu, put by the author entirely in a rural setting. They bring a rich lexis and phraseology related to the keeping of farm animals, their breeding and functions.

Nicolaus Cusanus presents a subtle theory of alterity. We will show why Cusanus does not consistently assign humans a position superior to other living beings, even when strong anthropocentric arguments seem to be present. Kazuhiko Yamaki (2017: 280), e.g., has recently pointed out that the attribution of a privileged position to humans in the world already fails logically, because the complicatio-explicatio scheme applies to all creatures. I would like to follow up on Yamaki’s argument that Cusanus at this point is rather concerned with describing a specific relationship between God and the creatures or the world. If this argument is extended to the question of humans and animals in Cusanus as a whole, the way in which these relations are to be figured becomes the focus of consideration. Just as Cusanus, in cosmology and anthropology, examines the perspectivity of knowledge and the decentralization of the Earth (as a noble star among other stars) without falling into pure perspectivism or decentralism, so traits of this reflective and (figuratively) ‘living’ thinking must also apply to the description of the relationship of living beings to one another or in relation to their Creator.

The nascent global age at the close of the Middle Ages introduced exotic objects from distant lands into Western Europe. Exotica from the natural world – naturalia – were frequently fashioned into ecclesiastical and seigniorial artifacts and housed in treasuries. The materials were sometimes re-identified in their new contexts, such as narwhal tusks understood as unicorn horns, which bestowed upon them additional meanings associated with those allegorical mythical creatures. This work investigates the movement, alteration, and use of such re-identified naturalia in late medieval society leading up to the Age of Discovery. It focuses on naturalia that retained their distinct morphological features after working, following the hypothesis that the identity of the animal, as indexed by a recognizable form or set of physical characteristics, was important. It additionally considers symbolic connotations and occult properties deriving from allegorization of matter to study the role played by the ornamentation of naturalia. This paper explores the discourse between extant tangible objects and contemporary texts such as bestiaries, lapidaries, and alchemical compendia to examine how the iconography of the artifact’s form and the iconology of the ornamentation contributed to the overall signification of the naturalia.

The responsibility for the COVID-19 pandemic was first ascribed to persons associated with the Huanan Seafood Market. However, many scientists suggest that this pandemic is actually a consequence of human intrusion into nature. This opens up a whole new perspective for an examination of direct and indirect, individual and collective responsibility concerning this particular pandemic, but also zoonotic pandemics as such. In this context, one of the key issues are the consequences of factory-farming of animals, which contributes to circumstances in which zoonotic pandemics emerge. Moreover, it is part of a larger economic system, global capitalism, whose logic implies certain coercion toward its participants to keep it essentially unchanged and therefore to make sure that livestock health remains “the weakest link in our global health chain” (FAO). However, even though the precise answer to the issue of moral responsibility for zoonotic pandemics outbreaks in general and the COVID-19 pandemic in particular cannot be given, it is possible to list certain indicators and make a framework helpful in ascribing moral responsibility to certain persons. The paper intends to do so by examining the notion of responsibility and by applying it to the issues mentioned. The results of this analysis show that it is misleading to place moral blame on people involved in actions that directly caused the animal-to-human transmission of a certain virus or on humanity as a whole.

The paper discusses funeral practices with regard to animals in ancient Berenike, investigated in two seasons of exploration, 2018 and 2019 (trenches BE18/19-107, BE01/19-48 and BE19/132). Three groups of animals are represented almost exclusively in the burials. These are cats, dogs and monkeys, buried mainly around the top and on what was the eastern slope of a sand dune. In the mid 1st century AD, an enclosure wall roughly 0.50 m thick was built enclosing a space of about 20 m2 with no apparent floor surface inside it. Outside the wall, a clay pavement surrounded the enclosure on at least three sides. Animal burials accumulated around this enclosure for the next century or so, achieving the greatest density close to the feature. By the 2nd century AD urban rubbish had encroached heavily upon the area taken up by the burials. Most likely in the beginning of the 3rd century AD, the wall was dismantled, perhaps together with the features that had been inside the enclosure (statue, column, tree?). Interestingly, two goats were buried by the two excavated corners (northeastern and northwestern ones) in this period. One of these represented a variant of the species not typical of Northeastern Africa.

In 2023, 2 novel pharmaceutical agents for small animals were released on the German market: the structural but non-functional analog of the inhibitory neurotransmitter gamma-aminobutyric acid pregabalin with an anxiolytic active component and the dopamine agonist ropinirole in form of eye drops to induce vomiting. Two established active veterinary pharmaceutical ingredients became available for additional species: The phosphorus compound butafosfan was additionally approved for horses, dogs and cats and the mineral sodium chloride as an isotonic sodium chloride solution was also approved for rabbits and guinea pigs. In addition, for small animals, there were new releases of an agent (dexamethasone) in a novel pharmaceutical formulation, one drug with a new route of administration (hydrocortisone aceponate), one drug with a new content of the active ingredient (firocoxib) as well as one veterinary drug with a new combination of active ingredients in a novel pharmaceutical formulation (gentamicin+mometasone+posaconazole). Furthermore, one combination of active ingredients (diprophylline+heptaminol) is available on the market for small animals again., Competing Interests: Die Autorin bestätigt, dass kein Interessenskonflikt besteht., (Thieme. All rights reserved.)

A heifer and a dairy cow were presented to our practice with cutaneous masses on the left side of their necks. Each mass had a diameter of approximately 20 cm. Both tumors had increased in size in recent weeks and were now prone to injuries from the stable equipment. Both animal owners agreed to surgical removal, which was performed under sedation and local anesthesia on a bovine treatment crush. The subsequent histopathological examinations of the extirpates revealed a melanocytoma in the young heifer and a cutaneous peripheral nerve sheath tumor (PNST) in the dairy cow. Both cases were benign tumors. The postoperative course was without complications and no recurrences were observed even more than a year later. No comparable tumors were found in related animals or in the offspring., Competing Interests: Die Autoren versichern, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

In 2023, no new active pharmaceutical ingredients were released on the German market for horses and food-producing animals. Two established veterinary active pharmaceutical ingredients became available for additional species: The phosphorus compound butafosfan was also approved for horses, dogs, and cats and the mineral sodium chloride as an isotonic sodium chloride solution was also approved for rabbits and guinea pigs. In addition, for small animals, there were new releases of an agent (pergolidmesilate) in a novel pharmaceutical formulation and a lower content of the active ingredient, one drug (fluralaner) in a smaller package size as well as one drug (oxalic acid dehydrate) with a new route of administration. Furthermore, one combination of active ingredients (diprophylline+heptaminol) is available on the market for horses and food producing animals again., Competing Interests: Die Autorin bestätigt, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

A 3-month-old and a 4-year-old cat were presented in the clinic due to regurgitation. The kitten had displayed the symptoms since it had been fed solid foods and was smaller than the litter mates. The 4-year-old cat showed sudden-onset symptoms for 5 days prior to presentation and had a good general condition. Positive contrast thoracic radiographs of both cats in lateral recumbency showed an esophageal dilatation cranial to the heart base and raised a suspicion of foreign material with soft tissue density in this area. In the 4-year-old cat, findings of ventrodorsal thoracic radiographs were compatible with a dextroposition of the aorta and a slightly marked focal left curve of the trachea. The echocardiographic examination of the kitten pictured a right sided aorta, hence a vascular ring anomaly with a dextroposition from the aorta was suspected. Aberrant blood flow as it is seen in a persistent ductus arteriosus was not apparent in the echocardiography. As a result of the sudden development of the clinical signs in the older cat without displaying any former history of regurgitation, an esophagoscopy was performed to exclude an intraluminal esophageal cause for the stricture as well as to extract the foreign material. In this cat, computed tomography imaging also displayed an aberrant left subclavian artery. Both cats recovered well after surgical correction.The diagnosis of a ring anomaly in the kitten via echocardiography is a rare situation. As is the diagnosis of a high-grade esophageal stricture due to a vascular ring anomaly at the age of 4 without a former history of regurgitation.Recovery was excellent in the younger cat. There were no signs of regurgitation 6 months after surgery. The adult cat was in good general condition without clinical symptoms according to the owners when presented for stitch removal. Unfortunately, the adult cat was lost to follow up., Competing Interests: Die Autoren erklären hiermit, dass sie keine geschützten, finanziellen, beruflichen oder anderen persönlichen Interessen an einer Firma oder einem Produkt haben, welche die dargestellten Inhalte oder Meinungen beeinflussen könnten., (Thieme. All rights reserved.)

Objective: The aim of this retrospective study was to analyze the clinical signs, confirmed or suspected toxicants, treatments and outcomes of poisoning cases in dogs presented over a 5-year period to the emergency service of a small animal referral center., Material and Methods: Medical records of 634 dogs were evaluated for a history of confirmed or presumed poisoning, suspected toxicant, clinical signs, treatment, and patient outcome. The probability of poisoning was graded based on the patient history, clinical findings, toxicologic examination and - in some cases - investigation of gastrointestinal contents., Results: Most dogs were hospitalized (77%) due to poisoning with mostly unknown toxicants (33%), food residues (18%), rodenticides (10%), tremorgenic mycotoxins (8%), medications (7%) and various plants (7%), followed by recreational drugs (5%), chemicals (4%), molluscicides (3%), antiparasitics (2%), feces (2%), nuts (2%), or toxins of animal origin (1%). Patients were presented predominantly showing neurologic signs (56%), reduced general condition (39%), and cardiovascular or hydration status abnormalities (26%). The survival rate was 97%. Most dogs were clinically unremarkable at the time of hospital discharge (70%). An additional 18% of the survivors had no apparent complications by the time of discharge. Toxicant-related complications (20.5%) included hemorrhage (4%), hepatic (4%), renal (4%), respiratory (3%), gastrointestinal (3%), cardiovascular (3%), and/or central nervous system (3%) complications, or clinically relevant hypoglycemia (0.3%)., Conclusion and Clinical Relevance: In the present study, poisoning in dogs was mostly associated with the ingestion of food residues, but the causative toxicant remained unidentified in many cases. Neurological signs were the major clinical presentation. The survival rate (97%) in this study was higher compared to those reported by other investigators., Competing Interests: Die Autoren bestätigen, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

Patellofemoral instability (PFI) describes a (sub)luxation of the patella in the patellofemoral joint. Pathophysiologically, PFI is usually due to a nonphysiological movement of the patella, so-called maltracking, either due to acute trauma with injury to the supporting ligamentous apparatus or due to the presence of anatomical risk factors. Radiologically assessable risk factors for maltracking include trochlear dysplasia, patella alta, patellar tilt, lateralization of the tibial tuberosity, torsional deformity and genu valgum. This article presents the most commonly used and best validated measurement techniques. In addition, the characteristic injury pattern after lateral patellar dislocation is shown., (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)

Human spongiform encephalopathies are rare transmissible neurodegenerative diseases of the brain and the nervous system that are caused by misfolding of the physiological prion protein into a pathological form and its deposition in the central nervous system (CNS). Prion diseases include Creutzfeldt-Jakob disease (CJD, sporadic or familial), Gerstmann-Straussler-Scheinker syndrome (GSS) and fatal familial insomnia (FFI). Prion diseases can be differentiated into three etiological categories: spontaneous (sporadic CJD), inherited (familial CJD, FFI, and GSS) and acquired (variant CJD and iatrogenic CJD). Most cases occur sporadically. Prion diseases can lead to a variety of neurological symptoms and always have an inevitably fatal course. Cerebrospinal fluid analysis and magnetic resonance imaging (MRI) play a crucial role in the diagnostics of prion diseases and may facilitate an early and reliable clinical diagnosis. A causal treatment or specific therapeutic agents are not yet available. In general, a palliative therapeutic concept is indicated., (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)

Objective: Four parameters of a decision tree for Selective Dry Cow Treatment (SDCT), examined in a previous study, were analyzed regarding their efficacy in detecting cows for dry cow treatment (DCT, use of intramammary antimicrobials). This study set out to review wether all parameters (somatic cell count [SCC≥ 200 000 SC/ml 3 months' milk yield recordings prior dry off (DO)], clinical mastitis history during lactation [≥1 CM], culturing [14d prior DO, detection of major pathogens] and California-Mastitis-Test [CMT, > rate 1/+ at DO]) are necessary for accurate decision making, whether there are possible alternatives to replace culturing, and whether a simplified model could replace the decision tree., Material and Methods: Records of 18 Bavarian dairy farms from June 2015 to August 2017 were processed. Data analysis was carried out by means of descriptive statistics, as well as employing a binary cost sensitive classification tree and logit-models. For statistical analyses the outcomes of the full 4-parameter decision tree were taken as ground truth., Results: 848 drying off procedures in 739 dairy cows (C DO ) were included. SCC and CMT selected 88.1%, in combination with CM 95.6% of the cows that received DCT (n=494). Without culturing, 22 (4.4%) with major pathogens (8x Staphylococcus [ S. ] aureus ) infected C DO would have been misclassified as not needing DCT. The average of geometric mean SCC (within 100 d prior DO) for C DO with negative results in culturing was<100 000 SC/ml milk, 100 000-150 000 SC/ml for C DO infected with minor pathogens, and ≥ 150 000 SC/ml for C DO infected with major pathogens (excluding S.aureus ). Using SCC during lactation (at least 1x > 200 000 SC/ml) and positive CMT to select C DO for DCT, contrary to the decision tree, 37 C DO (4.4%) would have been treated "incorrectly without" and 43 C DO (5.1%) "unnecessarily with" DCT. Modifications were identified, such as SCC<131 000 SC/ml within 100 d prior to DO for detecting C DO with no growth or minor pathogens in culturing. The best model for grading C DO for or against DCT (C DO without CM and SCC<200 000 SC/ml [last 3 months prior DO]) had metrics of AUC=0.74, Accuracy=0.778, balanced Accuracy=0.63, Sensitivity=0.92 and Specificity=0.33., Conclusions: Combining the decision tree's parameters SCC, CMT and CM renders suitable selection criteria under the conditions of this study. When omitting culturing, lower thresholds for SCC should be considered for each farm individually to select C DO for DCT. Nonetheless, the most accurate model could not replace the full decision tree., Competing Interests: Es besteht kein Interessenkonflikt., (Thieme. All rights reserved.)