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1. Rola komórek ILC2 w rozwoju zapalenia alergicznego.

Author

GAWRYSIAK, MATEUSZ, SZEWCZYK, ROBERT, KOWALSKI, MAREK L., and CHAŁUBIŃSKI, MACIEJ

Subjects
*INFLAMMATION, *NATURAL immunity, *IMMUNE response, *INFECTION, *INNATE lymphoid cells, *ALLERGIES
Abstract

ILC2s are a very important element of the innate immunity. Physiologically, the take part in the defense of the host against helmint infections. In pathological conditions, they become a link in the series of immune events of allergic inflammatory response. ILC2s activated by tissue-derived alarmins, such as IL-33, IL-25 and TSLP, release IL-4 and IL-5 affecting immune effectory cells, thus enhancing T2-dependent immune responses. [ABSTRACT FROM AUTHOR]

Published
2020

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