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Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

La diabetes tipo II es una enfermedad crónica creciente, que se asocia con el riesgo de daño renal, una complicación que puede llevar a la insuficiencia renal. Por ende, la detección temprana y el monitoreo del daño renal es fundamental en este tipo de pacientes. En este contexto, la cistatina C es un marcador endógeno confiable para evaluar la función renal, puesto que, su concentración no está influenciada por factores externos a diferencia de otros marcadores endógenos. El objetivo es analizar la cistatina C como marcador de daño renal en pacientes con diabetes mellitus tipo II. Se realizó una investigación exhaustiva, en las diferentes bases de datos, para identificar estudios relacionados al tema de interés. Se empleó el método PRISMA. Los estudios revisados demostraron una asociación entre la concentración elevada de la cistatina C con un riesgo de daño renal en pacientes con diabetes. Además, la cistatina C sugiere ser un marcador más sensible que la creatinina para detectar problemas renales en etapas tempranas. Se concluyó que la cistatina C es un marcador prometedor para la evaluación de daño renal en pacientes con diabetes tipo II, por su sensibilidad para detectar cambios tempranos y determinar la progresión de la enfermedad. [ABSTRACT FROM AUTHOR]

Copyright of Enfermería Nefrológica is the property of Sociedad Espanola de Enfermeria Nefrologica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Chronic renal disease constitutes a health problem due to its impact on individuals, society and economy. Taking into account the above-mentioned, and after a wide literature search, a clinical practice guide was designed in Luis Augusto Turcios Lima Polyclinic from Pinar del Río province, directed to primary health care professionals, aimed at improving the life quality of children and adolescents with this disease. It was elaborated by medicine methods based on the evidence, according to the consent and opinion of experts. It was possible to generalize this tool, give recommendations and up to date according to the new medical evidences. Finally, it was evaluated by experts as very recommended. [ABSTRACT FROM AUTHOR]

Chronic Kidney Disease (CKD) is considered a public health problem (1) with a high disease burden, affecting 9.1% of the world's population (2017) with 1.2 million deaths annually. (2. 3). In Argentina, the prevalence is estimated at 3.8 million cases (4), representing 12.7% of the population over 18 years of age. It is an asymptomatic disease and affects the population unequally, falling more heavily on the most vulnerable sectors. While premature mortality accounts for most of the disease burden, morbidity is also significant. Late treatment in advanced stages of the disease (dialysis and transplant) generates very high costs for the health system and significantly worsens people's quality of life (5). The marked lack of knowledge of kidney disease in the population and the factors that could cause it contribute to its progression. It is commonly identified in advanced stages due to another ailment, apparently different from kidney disease and other comorbidities, generally cardiovascular conditions, which is why many patients die from associated pathologies without detecting CKD. The leading causes of CKD are modifiable, except age and other biological, genetic, or hereditary conditions. It is necessary to develop public health promotion and disease prevention policies to address risk factors and substantially reduce the disease burden. [ABSTRACT FROM AUTHOR]

Copyright of Revista Médica de Risaralda is the property of Universidad Tecnologica de Pereira and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Alveolar hemorrhage is a medical emergency that compromises the patient's life, which requires early and timely diagnosis and treatment. The clinical case of a patient who presented a hypertensive emergency associated with unknown renal disease with the need for chronic dialysis is presented. Subsequently, he developed a picture of diffuse alveolar hemorrhage, being a lung-kidney syndrome, for which reason immunological studies were requested, which revealed positivity for Anca P. Vasculitis associated with anticytoplasmic antibodies was suspected, for which treatment with corticosteroids and cyclophosphamide was started with Good respiratory clinical evolution, but not renal compromise, however, through complementary studies it was not possible to elucidate the definitive diagnosis. [ABSTRACT FROM AUTHOR]

Renal disease is a serious and frequent complication in people with type 2 diabetes mellitus, especially in those over 50 years of age. Risk factors play a crucial role in the development and progression of this condition, and their early identification is essential to improve prevention and management. Study design: The methodology implemented corresponds to a qualitative-semi-quantitative approach, and the type of study was a bibliographic review of documentary analytical research. Objective: To investigate the risk factors associated with renal disease in people over 50 years of age with type 2 diabetes mellitus. Search for information: Access was obtained through scientific search engines such as PubMed; Elsevier; Scielo, Google Scholar. Inclusion criteria: The researches taken into consideration for the study were from the year 2017 to 2023. Results: The relationship between type 2 diabetes mellitus and the development of chronic kidney disease was greater than 50% The Preventive methods used for kidney disease in people older than 50 years were as follows: Blood pressure and cholesterol control, essential medications. Early detection of CKD. Most of the factors are given by Diabetes, obesity, dyslipidemia, hyperuricemia and cardiovascular. [ABSTRACT FROM AUTHOR]

Copyright of Salud Uninorte is the property of Fundacion Universidad del Norte and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Pediatría de Atención Primaria is the property of LUA Ediciones 3.0 S.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

After many years of looking for new mechanisms and strategies for cardiovascular and renal protection, sodium-glucose co-transport inhibitors or gliflozins appeared, demonstrating not only a notable and unexpected protective effect on various organ lesions: heart, arteries, kidneys, and brain but also an impressive event reduction. These effects were initially associated with better control of metabolic diseases such as diabetes. However, with time and the results, functional and structural improvements in said organs were verified in people without diabetes. These improvements went beyond the responses initially sought and extended to hemodynamic aspects and the benefits on cellular and subcellular structures and functions associated with protection in various tissues. These facts allow us to understand the notable reduction of the various events seen in the patients, including a reduction in mortality of around 30%. This review will show the existing evidence in renal, cardiovascular, and brain protection that translates into notable changes in clinical practice guidelines. We will also review cellular mechanistic knowledge, particularly improving mitochondrial function, which leads to less oxidative stress and inflammation. In summary, the review explains at least part of the reasons for these drugs nowadays to occupy the first line of treatment for cardiovascular and renal diseases. Finally, we will give reasons suggesting that gliflozins can be used in the future to prevent highly prevalent diseases. [ABSTRACT FROM AUTHOR]

Currarino syndrome is a hereditary disease with a low incidence, composed of a triad: anal stenosis, sacrococcygeal malformation and presacral mass. It can go unnoticed until adulthood and generate subdiagnoses. A 75-years-old male, black-skinned, urban origin patient with a history of arterial hypertension is described, who attended the hospital presenting hematuria, pain in the left lumbar fossa, and constipation. Radiological studies such as ultrasound, abdominal tomography and lumbosacral magnetic resonance were performed, which led to the diagnosis of a renal tumor, incomplete Currarino syndrome (given by two elements of the triad: sacrococcygeal malformation and presacral mass) associated with another spinal cord malformation disease, tethered cord. There are few cases reported in the world (almost 300), so it is considered a rare entity, but easy to diagnose due to new imaging technologies. [ABSTRACT FROM AUTHOR]

Copyright of Acta Médica Peruana is the property of Colegio Medico del Peru and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Salud Uninorte is the property of Fundacion Universidad del Norte and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Cytomegalovirus (CMV) and BK polyoma virus (BKV) coinfection is a severe and uncommon complication, manifested as tubulointerstitial nephritis in kidney grafts. Viral reactivations (CMV/BKV) cause renal dysfunction and are mainly related to the intensity of immunosuppression. We present 2 cases of renal transplant patients with CMV/BKV coinfection documented in renal biopsy. The gold standard for diagnosis is the identification of specific BKV/CMV inclusions by immunohistochemistry on histopathology. [ABSTRACT FROM AUTHOR]

Copyright of Enfermería Nefrológica is the property of Sociedad Espanola de Enfermeria Nefrologica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Detection of anxiety and depression in the recipient-donor pair (BinRD) during the kidney transplant protocol (KT) is important to establish psychoeducational interventions that help achieve success during and after KT. Objective: To determine the presence of anxiety and depression symptoms in the BinRD during the RT protocol and to identify characteristics and associated factors. Methods: Cross-sectional study, including 174 binomials being evaluated for TR. The Beck Depression Scale (BDI-II) and the Hospital Anxiety and Depression Scale (HADS) were applied at the beginning of the RT protocol. Results: Anxiety and depression symptoms were more frequent in recipient candidates than in donors ([anxiety 39% vs 21%] [depression 46% vs 15%]) (p<0.0001). The recipients presented a higher risk of depression (OR=4.770, 95% CI 2.854-7.974, p<0.0001) and anxiety (OR=2.383, 95% CI 1.478-3.841, p<0.001). Undertaking hemodialysis in private units (OR 0.264, 95%CI 0.106-0.662, p=0.004) or being on automated peritoneal dialysis (OR 0.386, 95%CI 0.173-0.862, p=0.020 was associated with less anxiety in recipients. Conclusions: a high frequency of anxiety and depression symptoms in the BinRD, so it is important to offer effective psychological interventions focused especially on the recipient during the donation evaluation process. [ABSTRACT FROM AUTHOR]

Chronic renal disease (CRD) is an important public health problem. There is no a national renal health program in Peru. There is evidence that the multidisciplinary model of care in patients with CRD delays progression and reduces all-cause mortality. Although there is no agreement on certain topics, such as at which glomerular filtration rate should the multidisciplinary team work, it is clear that outcomes are improved. Human and financial resources are needed to implement this approach. [ABSTRACT FROM AUTHOR]

Background: Mortality from Chronic Kidney Disease (CKD) has increased particularly in the Americas, the trend of wich could also be observed in Mexico, mainly due to the magnitude that Diabetes Mellitus and Arterial Hypertension have reached as the main causal factors. Objective: To examine the behavior and patterns associated with the demand for medical consultations for Kidney Disease (KD) in the IMSS during the period 2011-2020. Material and methods: According to the medical consultations for KD, general and adjusted rates were estimated by year and population assigned to first-level medical unit (UMF). Through geographic information systems and spatial statistics, the magnitude, behavior and patterns associated with the estimated indicators were analyzed. Results: From 2011 to 2020, the demand for KD medical consultations increased 45.8%; the behavior was unusually higher only in 1 out of 5 UMF (p < 0.05), up to 550.2 medical consultations per 1000 persons, wich were located mainly in Jalisco, Veracruz and Chiapas. The unusually higher pattern for medical consultations (p < 0.05) was observed in the same areas during each year of study. Conclusions: The demand for medical consultations by KD has increased in IMSS and has been significantly higher in UMF located in the west, east and southeast border of Mexico, which could indicate endemic areas of KD and require the development of epidemiological research to elucidate the causality of the disease. [ABSTRACT FROM AUTHOR]

Introduction: Detection of anxiety and depression in the recipient-donor pair (BinRD) during the kidney transplant protocol (KT) is important to establish psychoeducational interventions that help achieve success during and after KT. Objective: To determine the presence of anxiety and depression symptoms in the BinRD during the RT protocol and to identify characteristics and associated factors. Methods: Cross-sectional study, including 174 binomials being evaluated for TR. The Beck Depression Scale (BDI-II) and the Hospital Anxiety and Depression Scale (HADS) were applied at the beginning of the RT protocol. Results: Anxiety and depression symptoms were more frequent in recipient candidates than in donors ([anxiety 39% vs 21%] [depression 46% vs 15%]) (p<0.0001). The recipients presented a higher risk of depression (OR=4.770, 95% CI 2.854-7.974, p<0.0001) and anxiety (OR=2.383, 95% CI 1.478-3.841, p<0.001). Undertaking hemodialysis in private units (OR 0.264, 95%CI 0.106-0.662, p=0.004) or being on automated peritoneal dialysis (OR 0.386, 95%CI 0.173-0.862, p=0.020 was associated with less anxiety in recipients. Conclusions: a high frequency of anxiety and depression symptoms in the BinRD, so it is important to offer effective psychological interventions focused especially on the recipient during the donation evaluation process. [ABSTRACT FROM AUTHOR]

Copyright of Hospital a Domicilio is the property of Centro Internacional Virtual de Investigacion en Nutricion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Salud Pública is the property of Universidad Nacional de Colombia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Despite the existence of international guidelines for the correct assessment of dysmorphic hematuria, its categorization frequently presents a lot of variability, even among professionals in the same laboratory. Objective: To determine the level of knowledge of professional medical technologists for the assessment of dysmorphic red blood cells in urinary sediment. Material and Methods: Observational cross-sectional study. A measurement instrument was applied to assess knowledge about the preanalytical and analytical phase of the assessment of dysmorphic red blood cells in urinary sediment to 113 professionals with more than three years of experience in the area of ​​urinalysis and who work in state and private hospitals. Results. The mean score obtained was 5.4±1.9 out of 10 possible points; 85.0% of the respondents presented medium and insufficient knowledge and only 15.0% advanced knowledge; An association was observed between levels of knowledge and years of experience (p=0.006), no significant association was found with the variable gender (p=0.791) and hospital locations (p=0.888). Discussion: Low knowledge was evidenced in the preanalytical and analytical domains for the assessment of dysmorphic red blood cells, in addition to a significant association between the level of knowledge and the years of experience of the professional. [ABSTRACT FROM AUTHOR]

TINU syndrome (tubulointerstitial nephritis and uveitis) is a rare entity first described in 1975 by Dobrin et al.(1) Since then, about 300 cases have been described in the literature.(2) It typically affects children and adolescents with a clear predominance in women (9:1 in some studies). This disease consists of the association of systemic inflammatory syndrome, with an increase in acute phase reactants, proximal tubulo-interstitial nephropathy (glucosuria, leukocyturia) and non-granulomatous bilateral anterior uveitis, in most cases. We present a case of this entity with favorable evolution and therapeutic response. The initial symptoms were nonspecific, but there was a significant deterioration in renal function, for which steroid treatment was carried out with a successful response and without new relapses during follow-up. [ABSTRACT FROM AUTHOR]

Objectives: Kidney disease is one of the microvascular complications of diabetes mellitus (DM) with little research and a strong association with cardiovascular disease (CVD). The objective of this study is to characterize the prevalence of kidney disease in a population of patients with type 2 diabetes who attend outpatient control by cardiology, to evaluate its degree of investigation and whether its presence impacts on the achievement of therapeutic goals and use of antidiabetics with cardiovascular and kidney protective effect. Methods: Cross-sectional, observational and multicenter study, carried out in 44 centers in Argentina between May and July 2019. Results: A population with 693 patients with DM was included. The prevalence of CVD was 47.5% (329 patients) and that of microvascular disease was 42.3%. Albuminuria was evaluated only in 46.2% of the patients and was significantly higher in the group with renal impairment (RI). The presence of CVD in patients with RI was greater than in those without RI (64.8% vs. 42.2%; p = 0.0001). The presence of albuminuria was associated with a higher prevalence of CVD. The achievement of therapeutic goals was scarce and no differences were evidenced based on the presence of RI, except for the LDL goal. Low prescription of antidiabetic drugs with proven cardiovascular and kidney benefit was observed. Conclusions: This study highlights the importance of the active search for kidney disease in patients with DM, exposing the low scope of therapeutic goals and the prescription of antidiabetic drugs with cardiovascular and kidney benefit. [ABSTRACT FROM AUTHOR]

Background: In a context where the prevalence of Diabetes Mellitus and Hypertension has increased significantly in recent years, kidney diseases become important for the potential demand for specialized health care and resources required. Objective: To analyze the geographical distribution of Diabetic Nephropathy (DN) and Renal Insufficiency (RI) based on the medical consultations given in first-level units of IMSS during 2019, to identify the medical units with the highest burden of care. Material and methods: Ecological-exploratory study in which indicators were estimated for every thousand persons in relation to medical consultations given by ND and RI according to service time, first-level medical unit (UMF) and representation to analyze the magnitude and geographic distribution at the national level. Results: 45% of medical consultations were by ND and 52.4% by RI. The highest burden per DN was registered in UMF No. 50 Cd. Juarez (Chihuahua) and No. 49 Gabino Barreda (Veracruz Sur), with 1.7 first-time medical consultations and 148.3 subsequent medical consultations per 1,000 persons, respectively. While in UMF No. 40 Manlio Fabio Altamirano and No. 25 Cotaxtla, in Veracruz Norte, the highest burden was for RI, with 4.9 first-time medical consultations and 134.2 subsequent medical consultations per 1000 persons, respectively. Conclusions: The results could contribute to strengthening of medical units where it is necessary and the efficient allocation of resources available to meet the demand for health services of ND and RI in IMSS. [ABSTRACT FROM AUTHOR]

The article talks about the celebration of World Kidney Day, which takes place every second Thursday of March since 2006. This commemoration aims to raise awareness about kidney diseases and promote early detection of kidney problems. It highlights that 10% of the world's population suffers from some form of chronic kidney disease, and it is important to perform blood and urine tests to detect any malfunctioning in the kidneys. Additionally, it mentions the risk factors and provides recommendations to prevent kidney diseases. It emphasizes that kidney diseases are considered "silent killers" and that mortality from these diseases continues to increase. In Cuba, it is estimated that around 600,000 people have a kidney disease. The call is for prevention and taking care of kidney health. [Extracted from the article]

The American Congress of Nephrology 2022 took place in Orlando from November 1st to 6th, with the participation of 12,500 people in person and virtually. During the congress, various activities were carried out, such as plenary sessions, educational symposiums, and presentations of free communications and posters. Topics such as the future of nephrology, advances in treatments and techniques, prevention of future pandemics, and kidney xenotransplantation in humans were discussed. Other topics addressed included the use of antidiuretic hormone and mRNA as medicine, volume control in hemodialysis, cardiovascular risk in children undergoing dialysis treatment, preexisting kidney disease as a predictor of poor outcomes in COVID-19 cases, acute kidney injury, hypertension, and nephrolithiasis. The congress highlighted the importance of updating and exchanging knowledge in the field of nephrology. [Extracted from the article]

Background: According to the International Diabetes Federation, 18% of Mexican adults live with diabetes and it is expected that by 2030 it will occupy the seventh place in the world in number of cases. In the population covered by the Mexican Institute of Social Security, diabetes is the second cause of mortality, years lost due to premature death, years lived with disability and years of healthy life lost, placing it as one of the costliest diseases. Objective: Address in a timely and integrated manner chronic complications of type 2 diabetes mellitus, by implementing coordinated actions by multidisciplinary health team in the 3 levels of care. Material and methods: The process of developing the Integrated Care Protocols consisted of: 1) Prioritization of the health problem, 2) Formation of an interdisciplinary working group, 3) Development of content and systematic search for information 4) Analysis, review and discussion of interventions, 5) Review and validation by regulatory areas, 6) Dissemination and implementation. Conclusions: Adequate glycemic control, blood pressure, lipids and a healthy lifestyle are the key to delaying the presence of micro and macrovascular complications of DM2. However, the progression of the disease will eventually be inevitable, it will confront the health personnel and the patient with some of the complications. In this sense, timely detection and treatment to delay them becomes the main function of the health worker. [ABSTRACT FROM AUTHOR]

The American Congress of Nephrology 2022 took place in Orlando from November 1st to 6th, with the participation of 12,500 people in person and virtually. During the congress, various activities were carried out, such as plenary sessions, presentations of free communications and posters, and a trade exhibition. Topics such as the future of nephrology, advances in treatments and techniques, prevention of future pandemics, and kidney xenotransplantation in humans were discussed. Other topics addressed included the use of antidiuretic hormone and mRNA as medicine, volume control in hemodialysis, cardiovascular risk in children undergoing dialysis treatment, preexisting kidney disease as a predictor of poor outcomes in COVID-19 cases, acute kidney injury, hypertension, and nephrolithiasis. The congress highlighted the importance of updating and exchanging knowledge in the field of nephrology. [Extracted from the article]

Copyright of Cirugía y Cirujanos is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objectives. To assess the association between chronic disease (CD) and the need for palliative care (NPC). Materials and methods. An analytical cross-sectional study was carried out in a Peruvian hospital during 2019. Patients hospitalized with CD were included, and pregnant women and those hospitalized in critical units were excluded. The SPICT-ESTM instrument was used to assess the NPC; sociodemographic and clinical characteristics were also evaluated. The strength of association was calculated with Poisson regressions with robust variance to estimate crude prevalence ratios (PR) and adjusted prevalence ratios (aPR) by confounders. Results. A total of 172 patients were evaluated, the mean age was 61 years, where 54.7% were male and 123 patients had NPC. In the crude model, we found an association with having cerebrovascular disease (PR: 1.23; p=0.028), any type of cancer (PR: 1.38; p<0.001), heart disease (PR: 1.29; p=0.007), nephropathy (PR: 1.42, p<0.001) and Alzheimer's disease (PR: 1.42; p<0.001). The association was maintained for most of the evaluated CDs in the adjusted model, except for heart disease (aPR: 1.11; p=0.320). The association strength was lower for diabetes mellitus (PR: 0.78; p=0.044). Conclusion. NPC in hospitalized chronically ill patients is high and more frequent in patients with cancer, cerebrovascular disease, renal problems and Alzheimer's disease. Care programs for patients with diabetes mellitus may decrease NPC. [ABSTRACT FROM AUTHOR]

Copyright of Enfermería Nefrológica is the property of Sociedad Espanola de Enfermeria Nefrologica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)