Search

Introduction: Rational drug use is a process involving healthcare providers, legislators and the whole society. Here, we aimed to investigate the attitudes and behaviors related to 'Rational Drug Use' in Havutlu district of Adana province. Materials and Methods: In our study, we conducted a questionnaire consisting of 28 questions about the sociodemographic characteristics and the attitudes and behaviors related to "Rational Drug Use" we implemented. The sample size is 358. We also acquire the necessary statutory authorizations and approval of the ethics committee. The type of study is cross-sectional. In analysis, frequency analysis and chi-square test were used with SPSS version 19.0. Results: Average of 4.1±2.6 box medicine was left unused. 26% of the participants stated that they offered medication to their relatives, and the use of herbal medicines been found as 15.9%. 87.7% of the participants stated that the medication was overturned after the expiry date and 3.4% would continue to use it. The average annual antibiotic use of the participants was found to be 2.3±1.4. 59.8% of those who took antibiotic treatment stated that they terminated the treatment voluntarily without ending the treatment period. In order to be found at home, the prescription for medication seems to be significantly higher in women with a level of income below 1,000 TL (p=0.02) and with chronic disease (p lt;0.001). The presence of chronic illness appears to be associated with both herbal medication use (p lt;0.001) and home medication (p=0.008). Conclusion: When attitudes and behaviors related to rational drug use are examined, it is concluded that some variables have an influence and that inappropriate use is common throughout the society.

It is that diabetes mellitus increases tendency to develop infections and thrombosis. Impairment of various mechanisms and agents of humoral and cellular immune systems can be expected. Disturbances of platelet function, coagulation factors, and vascular structure predispose diabetics to thrombotic events. The course of both infections and thrombotic events is often worse than in non-diabetic patients. Presently described is 94-year-old male patient with diabetes who had orbital cellulitis that became complicated with cavernous sinus thrombosis (CST). He was admitted to endocrinology clinic with diagnoses of orbital cellulitis, urinary tract infection, hyperosmolar nonketotic state, acute renal failure, and compensated metabolic acidosis secondary to uremia. Despite immediate antibiotherapy, hydration, and additional required treatment, patient did not respond and died as a result of CST. There must be awareness, especially for diabetic patients, that orbital infections may spread to nearby cavernous sinuses and cause potentially lethal septic CST. Early diagnosis and immediate treatment are essential. [ABSTRACT FROM AUTHOR]

Background: Described in the present study is an analysis of appropriateness of antibiotics use for patients in whom infectious agent was detected. Data from patients in orthopedics and traumatology departments of two different hospitals in the same district were evaluated according to rational antibiotic drug use and culture antibiogram results. Methods: Data of patients diagnosed with infection between January 1, 2014 and December 31, 2015 in orthopedics and traumatology departments of two different hospitals were analyzed. Patients diagnosed with malignancy or who were discharged from other departments were excluded. A standard form was created to collect demographic data, culture antibiogram results, details of infectious agent, source of culture material, posology of antibiotic used, duration and appropriateness of use, and length of hospital stay. Costs were estimated based on 2014 Ministry of Health price list, and mean price of antibiotics per patient was recorded. Descriptive analyses were also completed. Results: It was determined that appropriate antibiotics for detected infectious agent were not always selected. Though there were cheaper effective antibiotics that could have been used according to antibiogram results, more expensive antibiotics were often chosen, which results in higher costs. Conclusion: Multidisciplinary approach in patient care and use of evidence-based guidelines should be increased. Teams should be formed and led by infectious disease and pharmacology specialists. New strategies should be developed immediately in health economics and new pharmacoeconomic models should be initiated in orthopedics and traumatology departments. [ABSTRACT FROM AUTHOR]

AIM: The objective of this study is to show the alterations in frequency and cost of antibiotic use in neonatal and pediatric intensive care units of a state hospital after it started to service as an education and research hospital. We also aimed to raise an awareness related to rational antibiotic use. METHODS: The surveillance of antibiotic use and comparison of costs were evaluated in 392 patients in between August 2013-January 2014. The rate and cost of antibiotic use during last 90 days before the protocol of state hospital to research and education hospital and the first 90 days after protocol were evaluated. Antibiotics were assessed according to the treatment protocols of the Committee of Rational Drug Use, Infection Control Committee and Antibiotic Control Committee. Antibiotics were provided from administrative system and the data related to costs were obtained from Ministry of Health and Ministry of Finance. The demographic data and the data related to indication for admission to intensive care units, antibiotic dosages and pathogens causing infections were also obtained. For statistical analysis, SPSS program was used and descriptive analysis were made. In comparison of the groups, Mann Whitney U and chi-square tests were used. The data were evaluated within a 95% confidence interval. RESULTS: In first and second period, 143 patients were hospitalized for 3.18±1.13 days and 105 patients were hospitalized for 2.69±4.14 days in pediatric intensive care unit(PICU); 79 patients were hospitalized for 17.29±3.61 days and 65 patients stayed for 21.29±3.29 days in neonatal intensive care unit(NICU), respectively. In the first and second period, cost of antibiotics in PICU was found 341.81±744.49 (med:14.91) and 585.35±796.62 (med:256.44) (p=0.02) Turkish Liras (TL); in NICU 137.92±178.78 (med:14.59) and 247.40±370.13(med:19.23) (p=0.76) TL respectively. CONCLUSİON: In the second period, in PICU, duration of hospitalization was found to decrease and costs of antibiotics were higher. In NICU, the duration of hospitalization was longer and although statistically insignificant, costs of antibiotics were slightly higher. Differences between the two periods in term of cost showed that, PICUs and ICUs should revisit their antibiotic preferences from the viewpoint of a pediatric infectious disease physician. [ABSTRACT FROM AUTHOR]

Objective: Antibiotics are the most frequently used drugs in our country, as being all over the world. It has been shown that the rate of inappropriate use of antibiotics is around 40% to 60% in hospitals. Excessive and inappropriate use of antibiotics causes emergence of resistant organisms, significant adverse effects, increased costs and increased morbidity and mortality. Methods: This study was carried out at Midyat State Hospital between June 2007 and June 2008. The period of time between June 2006 and June 2007 and between June 2007 and June 2008 are defined as Period I and II, respectively. Antibiotics which were given to inpatients and for surgical prophylaxis were followed up. Subsequently, usage ratios of antibiotics in Period I and II were compared for a cost-utility analysis. Results: The total cost of inappropriate antibiotic use per year was calculated as 55 750.4 TL in our hospital. However, the most frequent cause of inappropriate use in surgical prophylaxis was related to prolonged use of prophylactic antibiotics (16.2%). Conclusions: Several strategies for regulating antimicrobial prescribing practices may be proposed, such as formulary replacement or restriction, healthcare provider education, feedback activities, and approval from an infectious diseases physician. However, a multidisciplinary antibiotic team organized for hospitals to approve the appropriate antibiotic use may be another alternative. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Pediatric Infection / Çocuk Enfeksiyon Dergisi is the property of Journal of Pediatric Infection / Cocuk Enfeksiyon Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Health Sciences / Sağlık Bilimleri Dergisi is the property of Erciyes Universitesi Saglik Bilimleri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)