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64 results on '"Luzzaro F"'

1. Colistin resistance superimposed to endemic carbapenem-resistant Klebsiella pneumoniae: a rapidly evolving problem in Italy, November 2013 to April 2014

Author

Monaco, M, Giani, T, Raffone, M, Arena, F, Garcia Fernandez, A, Pollini, S, Network EuSCAPE Italy, Grundmann, H, Pantosti, A, Rossolini, Gm, Collaborators, Barbaro, A, Campion, L, Catania, M, De Bernochi, A, Di Taranto AM, Dusi, P, Grandesso, S, Luzzaro, F, Manso, E, Meledandri, M, Mencacci, A, Milano, F, Parisi, G, Pecile, P, Restelli, A, Rocchetti, A, Arrigo, C, Rossi, M, Santino, Iolanda, Sarti, M, and Sartor, A.

Subjects
Carbapenem, Endemic Diseases, Epidemiology, Carbapenem resistant Klebsiella pneumoniae, Microbial Sensitivity Tests, Drug resistance, Polymerase Chain Reaction, beta-Lactamases, Microbiology, Colistin resistance, Bacterial Proteins, Drug Resistance, Multiple, Bacterial, Virology, polycyclic compounds, medicine, Humans, biology, Colistin, Public Health, Environmental and Occupational Health, Outbreak, biochemical phenomena, metabolism, and nutrition, Laboratories, Hospital, bacterial infections and mycoses, medicine.disease, biology.organism_classification, Health Surveys, Enterobacteriaceae, Anti-Bacterial Agents, Klebsiella Infections, Klebsiella pneumoniae, Carbapenems, Italy, Klebsiella pneumonia, Sentinel Surveillance, medicine.drug
Abstract

Consecutive non-replicate clinical isolates (n=191) of carbapenem non-susceptible Enterobacteriaceae were collected from 21 hospital laboratories across Italy from November 2013 to April 2014 as part of the European Survey on Carbapenemase-producing Enterobacteriaceae (EuSCAPE) project. Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-KP) represented 178 (93%) isolates with 76 (43%) respectively resistant to colistin, a key drug for treating carbapenamase-producing Enterobacteriaceae. KPC-KP colistin-resistant isolates were detected in all participating laboratories. This underscores a concerning evolution of colistin resistance in a setting of high KPC-KP endemicity.

Published
2014

24. EPIDEMIOLOGY OF BLOODSTREAM INFECTIONS AND TIME TO DETECTION OF POSITIVE BLOOD CULTURES: AN EVALUATION OF THE AUTOMATED BACT/ALERT AND BACTED 9240 SYSTEMS

Author

Endimiani A, Tamborini A, Luzzaro F, Lombardi G, and Antonio Toniolo

Subjects
Microbiological Techniques, Automation, Time Factors, Sepsis, Humans, Bacteremia, Reagent Kits, Diagnostic, Culture Media
Abstract

Data of 3,097 blood culture sets processed with the BacT/Alert system in 1997 were compared to those of 3,158 blood culture sets processed with BACTEC 9240 in 1999. Agents responsible for bloodstream infections (BSI) were detected in 15.9% and 20.0% of blood cultures in 1997 and 1999, respectively. The incidence of BSI was 9.3 (1997) vs. 11.3 (1999) per 1,000 admissions. In both years, S. aureus was the most frequent isolate, followed by E. coli. Overall, the mean detection time (MDT) obtained with the BACTEC 9240 was significantly shorter than that of the BacT/Alert. Significant MDT differences were found for all organisms, except for Enterobacteriaceae (12.7 vs. 10.6 h). With both systems, over 95% positive samples were detected within 3 days, indicating that a 4-day incubation protocol may disclose most BSI agents. Thus, the added speed of the BACTEC 9240 allowed a particularly fast clinical management of septic patients.

Published
2002

48. Batteriologia

Author

Toniolo, Antonio, Bossi, G, Falcone, V, Luzzaro, F, Mossa, A, and Rossi, A.

Published
1995

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