Search

Multiple myeloma (MM) is a disease of older people, yet factors relating to comorbidity and frailty may threaten treatment tolerability for many of this heterogenous group. There has been increasing interest in defining specific and clinically relevant frailty assessment tools within the MM population, with the goal of using these frailty scores, not just as a prognostic instrument, but also as a predictive tool to allow for a frailty‐adapted treatment approach. This paper reviews the various frailty assessment frameworks used in the evaluation of patients with MM, including the International Myeloma Working Group Frailty Index (IMWG‐FI), the Mayo Frailty Index and the simplified frailty scale. While the IMWG‐FI remains the most widely accepted tool, the simplified frailty scale is the most user‐friendly in busy day‐to‐day clinics based on its ease of use. This paper summarises the recommendations from the Myeloma Scientific Advisory Group (MSAG) of Myeloma Australia, on the use of frailty assessment tools in clinical practice and proposes a frailty‐stratified treatment algorithm to aid clinicians in tailoring therapy for this highly heterogeneous patient population. [ABSTRACT FROM AUTHOR]

The objective of this paper is to assess whether existing pavement temperature prediction algorithms can be used to reliably determine Performance Grade (PG) design temperatures for Australian asphalt pavements. The results show good agreement between internationally and locally developed pavement temperature algorithms for the prediction of high pavement design temperature. There is more variability between models in the prediction of low pavement design temperature. The paper also provides a set of PG grading results for a range of Australian asphalt binders. The findings indicate that for a given design situation harder bitumen, ormore highly modified binder would be specified in Australia than in jurisdictions using the PG system. [ABSTRACT FROM AUTHOR]

To solve the problem of feature selection and error correction after mode decomposition and improve the ability of power load forecasting models to capture complex time series information, a two-stage short-term power load forecasting method based on recursive feature elimination with a cross validation (RFECV) algorithm and time convolution network–efficient channel attention mechanism–long short-term memory network (TCN–ECA–LSTM) is presented. First, the load sequence is decomposed into a relatively stable set of modal components using variational mode decomposition. Then, the RFECV-based method filters the feature set of each modal component to construct the best feature set. Finally, a two-stage prediction model based on TCN–ECA–LSTM is established. The first stage predicts each modal component and the second stage reconstructs the load forecast based on the predicted value of the previous stage. This paper takes actual data from New South Wales, Australia, as an example, and the results show that the method proposed in this paper can build the feature set reliably and efficiently and has a higher accuracy than the conventional prediction model. [ABSTRACT FROM AUTHOR]

Chronic disease identification and management is a significant issue in Australia, with general practice being the primary contact point for those at risk of, or living with, chronic disease. However, there is a well-described gap between guideline recommendations for chronic disease management and translation in the general practice setting. In 2018, a group of researchers, clinicians and software developers collaborated to develop a tool to support the identification and management of chronic disease in general practice, with the aim to create a platform that met the needs of general practice. The co-design process drew together core principles and expectations for the establishment of a technological platform, called Future Health Today (FHT), which would sit alongside the electronic medical record (EMR) management system within general practice. FHT used algorithms applied to EMR data to identify patients with, or at risk of, chronic disease and requiring review. Using chronic kidney disease as a clinical focus, the FHT prototype was piloted in a large, metropolitan general practice, and a large regional general practice. Based on user feedback, the prototype was further developed and improved. This paper provides a report on the key features and functionalities that participants identified and implemented in practice. Future Health Today is a new platform, co-designed by general practice for general practice, which aims to streamline the identification and management of chronic disease to improve health outcomes. This paper describes the development of the technology platform and how it was optimised through an implementation study in general practice. [ABSTRACT FROM AUTHOR]

Simple Summary: In radiotherapy treatment, organs at risk and target volumes are contoured by the clinicians to prepare a dosimetry plan. In retrospective data, these structures are not often standardised to universal names across the patients plans, which is required to enable data mining and analysis. In this paper, a new method was proposed and evaluated to automatically standardise radiotherapy structures names using machine learning algorithms. The proposed approach was deployed over a dataset with 1613 patients collected from Liverpool & Macarthur Cancer Therapy Centres, New South Wales, Australia. It was concluded that machine learning techniques can standardise the dosimetry plan structures, taking into consideration the integration of multiple modalities representing each structure during the training process. In progressing the use of big data in health systems, standardised nomenclature is required to enable data pooling and analyses. In many radiotherapy planning systems and their data archives, target volumes (TV) and organ-at-risk (OAR) structure nomenclature has not been standardised. Machine learning (ML) has been utilised to standardise volumes nomenclature in retrospective datasets. However, only subsets of the structures have been targeted. Within this paper, we proposed a new approach for standardising all the structures nomenclature by using multi-modal artificial neural networks. A cohort consisting of 1613 breast cancer patients treated with radiotherapy was identified from Liverpool & Macarthur Cancer Therapy Centres, NSW, Australia. Four types of volume characteristics were generated to represent each target and OAR volume: textual features, geometric features, dosimetry features, and imaging data. Five datasets were created from the original cohort, the first four represented different subsets of volumes and the last one represented the whole list of volumes. For each dataset, 15 sets of combinations of features were generated to investigate the effect of using different characteristics on the standardisation performance. The best model reported 99.416% classification accuracy over the hold-out sample when used to standardise all the nomenclatures in a breast cancer radiotherapy plan into 21 classes. Our results showed that ML based automation methods can be used for standardising naming conventions in a radiotherapy plan taking into consideration the inclusion of multiple modalities to better represent each volume. [ABSTRACT FROM AUTHOR]

Timely monitoring of pavement sub-surface layer thickness and condition evaluation is essential to ensure stable pavement performance and safety under heavy traffic loading. In addition, accurate estimation of pavement layer thicknesses is required for condition evaluation, overlay design/quality control assurance, and structural capacity evaluation of existing pavements to predict its remaining service life. Traditionally this vital information is ascertained through coring/drilling and visual inspections. In contrast to these current techniques, ground-penetrating radar (GPR) is a nondestructive technique gaining popularity in pavement asphalt layer thickness estimation and structural condition monitoring. Its high-quality data contains vital pavement condition information, and survey costs are reasonably economic. In this work, GPR data were acquired along a toll road in Queensland, Australia, using the GSSI 4-channel SIR30 GPR unit. Asphalt layer thickness information is considered an important input parameter for condition assessment, pavement performance, and lifetime modelling. This work presents an automated segmentation framework to evaluate pavement conditions for a large pavement network. The developed algorithm uses GPR asphalt thickness data as input and generates segments with decision boundaries utilising a cascaded k-means and DBSCAN approach that works in two steps: 1) centroid initialisation using k-means algorithm, 2) clustering using DBSCAN algorithm. Presented in this paper is the workflow of the cascaded method that is applicable to automated analysis of GPR asphalt thickness data. The performance of the cascaded kmeans and DBSCAN algorithm was evaluated in terms of entropy compared with traditional k-means and traditional DBSCAN algorithms. The results show that the proposed method outperforms its constituents. Based on the results of this study, the method presented in this paper is cost-effective, economical and robust for segmenting large pavement network with GPR data. [ABSTRACT FROM AUTHOR]

This paper proposes a spatiotemporal clustering algorithm and its implementation in the R package spotoroo. This work is motivated by the catastrophic bushfires in Australia throughout the summer of 2019-2020 and made possible by the availability of satellite hotspot data. The algorithm is inspired by two existing spatiotemporal clustering algorithms but makes enhancements to cluster points spatially in conjunction with their movement across consecutive time periods. It also allows for the adjustment of key parameters, if required, for different locations and satellite data sources. Bushfire data from Victoria, Australia, is used to illustrate the algorithm and its use within the package. [ABSTRACT FROM AUTHOR]

As more and more photovoltaic (PV) systems are integrated into the grid, the intelligent operation of the grid system is facing significant challenges. Therefore, accurately forecasting PV power output at various time scales is particularly urgent. To meet this demand, this paper proposes an LSTM-Informer model based on an improved Stacking ensemble algorithm (ISt-LSTM-Informer). The proposed model improves the k-fold cross validation in the traditional Stacking algorithm to a time-series cross validation for integrating time-series forecasting models. Simultaneously, it utilizes long short-term memory (LSTM) and Informer as the base models. By integrating the advantages of the two base models, the ISt-LSTM-Informer achieves accurate short and medium-term PV power forecasting. To validate the effectiveness of the model, a historical dataset from a PV system located in Uluru, Australia, is used for various types of experiments. Among them, comparative experiments validate the superiority of the model. Compared with five other methods, the ISt-LSTM-Informer obtains 21 optimal results for the four evaluation metrics of RMSE, MAE, MAPE, and R 2 across eight forecasting time scales. In addition, different combinations of base models are conducted to verify the advantages of the Stacking ensemble algorithm and the two base models, respectively. • A novel multi-timescale photovoltaic power forecasting model is proposed. • Time-series cross validation is introduced into the Stacking algorithm. • LSTM and Informer are utilized as the base models of the Stacking algorithm. • Various methods are compared to verify the proposed model's effectiveness. • The model's predictive accuracy is illustrated through various visualization methods. [ABSTRACT FROM AUTHOR]

Modelling workflow for BRF-LSTM and BRF-GRU predictive models. [Display omitted] • Deep learning hybrid predictive model (BRF-LSTM) is built for streamflow forecasting. • Climate indices, rainfall and periodicity are factored for accurate predictions. • Adopts feature algorithm (i.e. Boruta) with long short-term memory and gated recurrent unit. • Six gauging sites tested; BRF-LSTM yields > 98% errors in ± 0.015 m, ~1.30% relative error. • The proposed model is useful for hydrological and strategic water resources planning. Long-term forecasting of any hydrologic phenomena is essential for strategic environmental planning, hydrologic and other forms of structural design, agriculture, and water resources management. Climate mode indices, utilising machine learning methods, are frequently considered as predictor variables in order to forecast several different hydrological variables. In this study, a feature selection algorithm based on two different deep learning models, i.e., long short-term memory and a gated recurrent unit, is applied to improve the forecasting capability of streamflow water levels at six gauging stations in the Murray Darling Basin of Australia. This paper therefore aggregates the significant antecedent lag memory of climate mode indices, rainfall, and the monthly factor based on the periodicity as the predictor variables to attain significantly accurate stream water level forecasts. This novel method identifies an improved relationship between the stream water level and climate mode indices through the aggregation of the significant lagged datasets capturing the historical features to predict the future streamflow water level. The boruta feature selection algorithm (BRF) was then applied in a two phase process before and after attaining the significant lagged inputs to screen the optimum predictor variables. The merits of the forecast models were evaluated through different performance evaluation criteria. The results show that the accumulated significant lagged inputs based on climate mode indices, along with the rainfall and periodicity factors are seen to provide improved forecasting of the SWL over the non-BRF deep learning approaches where no prior feature selection was applied. The hybrid LSTM method (i.e., BRF-LSTM model) achieved a unique advantage in terms of SWL forecasting, particularly attaining over 98% of the predictive errors lying within a band of +/-0.015 m with relatively low relative errors (RRMSE ≈1.30% and RMAE ≈ 0.882%), outperforming all of the benchmark models. It is also found that the periodicity factor has a potential influence on the accuracy of the forecast models for the four monitored study stations. This study concludes that the newly developed hybrid deep learning approaches, coupled with the BRF feature selection, provide improved forecasting performance. The hybrid approach developed in this paper can therefore be used to provide a strong provide predictive response algorithm for the hydrological variables that were influenced by the low-frequency variability of the climate model indices in respect to streamflow water level. [ABSTRACT FROM AUTHOR]