Search

Your search keyword '"Bi, Rui"' showing total 563 results
Start Over Author "Bi, Rui" Publication Type Academic Journals
563 results on '"Bi, Rui"'

10. Spin–lattice relaxation with non-linear couplings: Comparison between Fermi's golden rule and extended dissipaton equation of motion.

Author

Bi, Rui-Hao, Su, Yu, Wang, Yao, Sun, Lei, and Dou, Wenjie

Subjects
*SPIN-lattice relaxation, *SINGLE molecule magnets, *MAGNETIC relaxation, *NONLINEAR systems, *QUBITS
Abstract

Fermi's golden rule (FGR) offers an empirical framework for understanding the dynamics of spin–lattice relaxation in magnetic molecules, encompassing mechanisms like direct (one-phonon) and Raman (two-phonon) processes. These principles effectively model experimental longitudinal relaxation rates, denoted as T 1 − 1 . However, under scenarios of increased coupling strength and nonlinear spin–lattice interactions, FGR's applicability may diminish. This paper numerically evaluates the exact spin–lattice relaxation rate kernels, employing the extended dissipaton equation of motion formalism. Our calculations reveal that when quadratic spin–lattice coupling is considered, the rate kernels exhibit a free induction decay-like feature, and the damping rates depend on the interaction strength. We observe that the temperature dependence predicted by FGR significantly deviates from the exact results since FGR ignores the higher order effects and the non-Markovian nature of spin–lattice relaxation. Our methods can be easily extended to study other systems with nonlinear spin–lattice interactions and provide valuable insights into the temperature dependence of T1 in molecular qubits when the coupling is strong. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

22. Electronic friction near metal surface: Incorporating nuclear quantum effect with ring polymer molecular dynamics.

Author

Bi, Rui-Hao and Dou, Wenjie

Subjects
*METALLIC surfaces, *QUANTUM rings, *QUANTUM theory, *GROUND state energy, *FRICTION, *MOLECULAR dynamics
Abstract

The molecular dynamics with electronic friction (MDEF) approach can accurately describe nonadiabatic effects at metal surfaces in the weakly nonadiabatic limit. That being said, the MDEF approach treats nuclear motion classically such that the nuclear quantum effects are completely missing in the approach. To address this limitation, we combine Electronic Friction with Ring Polymer Molecular Dynamics (EF-RPMD). In particular, we apply the averaged electronic friction from the metal surface to the centroid mode of the ring polymer. We benchmark our approach against quantum dynamics to show that EF-RPMD can accurately capture zero-point energy as well as transition dynamics. In addition, we show that EF-RPMD can correctly predict the electronic transfer rate near metal surfaces in the tunneling limit as well as the barrier crossing limit. We expect that our approach will be very useful to study nonadiabatic dynamics near metal surfaces when nuclear quantum effects become essential. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

48. CFH Variants Affect Structural and Functional Brain Changes and Genetic Risk of Alzheimer’s Disease

Author

Zhang, Deng-Feng, Li, Jin, Wu, Huan, Cui, Yue, Bi, Rui, Zhou, He-Jiang, Wang, Hui-Zhen, Zhang, Chen, Wang, Dong, Kong, Qing-Peng, Li, Tao, Fang, Yiru, Jiang, Tianzi, and Yao, Yong-Gang

Subjects
Biological Psychology, Biomedical and Clinical Sciences, Neurosciences, Psychology, Aging, Prevention, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Genetics, Human Genome, Acquired Cognitive Impairment, Neurodegenerative, Brain Disorders, Dementia, Alzheimer's Disease, 4.1 Discovery and preclinical testing of markers and technologies, Aetiology, 2.1 Biological and endogenous factors, Detection, screening and diagnosis, Neurological, Aged, Alzheimer Disease, Asian People, Brain, China, Complement Factor H, Endophenotypes, Female, Genetic Predisposition to Disease, Genetic Testing, Genotype, Humans, Male, Middle Aged, Polymorphism, Single Nucleotide, RNA, Messenger, Risk Factors, Alzheimer's Disease Neuroimaging Initiative, Medical and Health Sciences, Psychology and Cognitive Sciences, Psychiatry, Biological psychology
Abstract

The immune response is highly active in Alzheimer's disease (AD). Identification of genetic risk contributed by immune genes to AD may provide essential insight for the prognosis, diagnosis, and treatment of this neurodegenerative disease. In this study, we performed a genetic screening for AD-related top immune genes identified in Europeans in a Chinese cohort, followed by a multiple-stage study focusing on Complement Factor H (CFH) gene. Effects of the risk SNPs on AD-related neuroimaging endophenotypes were evaluated through magnetic resonance imaging scan, and the effects on AD cerebrospinal fluid biomarkers (CSF) and CFH expression changes were measured in aged and AD brain tissues and AD cellular models. Our results showed that the AD-associated top immune genes reported in Europeans (CR1, CD33, CLU, and TREML2) have weak effects in Chinese, whereas CFH showed strong effects. In particular, rs1061170 (P(meta)=5.0 × 10(-4)) and rs800292 (P(meta)=1.3 × 10(-5)) showed robust associations with AD, which were confirmed in multiple world-wide sample sets (4317 cases and 16 795 controls). Rs1061170 (P=2.5 × 10(-3)) and rs800292 (P=4.7 × 10(-4)) risk-allele carriers have an increased entorhinal thickness in their young age and a higher atrophy rate as the disease progresses. Rs800292 risk-allele carriers have higher CSF tau and Aβ levels and severe cognitive decline. CFH expression level, which was affected by the risk-alleles, was increased in AD brains and cellular models. These comprehensive analyses suggested that CFH is an important immune factor in AD and affects multiple pathological changes in early life and during disease progress.

Published
2016

Catalog

Books, media, physical & digital resources
See catalog results