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A single intraperitoneal arginine injection increases the amidopyrin demethylation on 230% and aniline hydroxylation on 74% in rat liver microsomes. For all this the rate of lipid peroxidation estimated by the number of dienic conjugates and Schiff bases does not change. At the same time the exogenous arginine decreases the lipid bilayer microviscosity on 35% and increases the degree of protein submersion into lipid matrix on 54%. The experiments in vitro confirm the fact of activation in cytochrome P-450 isoform by arginine. A possible arginine effect on microsome membrane is under discussion.

The character and results of eye burn treatment have been studied in 226 patients (307 eyes) aged from 10 to 80 years. The analysis of the character of eye burns has shown that the overwhelming majority of them were chemical ones (80.54%), of them 50% being alkaline. As to degree of severity, burns of moderate degree predominated (58.74%). The greatest part of the sufferers had everyday-life burns (67.7%). Results of treatment depended, mainly, on the severity of the burn. By the results of treatment, the patients were divided into 4 groups: group I included patients with total restoration of corneal transparency, who can return to their former labor activity; group-II patients with partially lost visual functions on account of remained, moderately expressed cicatricial opacifications of the cornea, who in future require repeated courses of resolving therapy; group-III patients with a remarkable loss of visual functions on account of coarse cicatricial opacifications of the cornea, who in future require surgical treatment--keratoplasty, keratoprosthesing and other surgical interventions; group IV-patients with total restoration of corneal transparency after treatment, but with insufficiently high visual acuity because of associated changes in the optic media and the eye fundus (beginning cataract, macular dystrophy, etc.), who require dispensary observation and treatment of associated diseases.