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In this work, the tungsten‐copper composites were fabricated by binder jet 3D printing technology. The effects of different printing layer thicknesses (50 μm to 100 μm) on the green density and green strength were investigated. Then, under the optimal layer thickness, the effects of different sintering temperatures (1300 °C to 1600 °C) on the microstructure and densification of tungsten‐40 wt.–% copper composites were studied. The experimental results showed that when the printing layer thickness was set as a lower value (50 μm), the tungsten‐40 wt.–% copper green part had the best strength and its density reached a maximum value of 60.73 %. After sintering for green parts printed with 50 μm layer thickness, the relative density, thermal conductivity and electrical conductivity of sintered parts first increased and then decreased with increasing sintering temperature. In our experiments, the tungsten‐40 wt.–% copper sample fabricated by binder jet 3D printing with a printing layer thickness of 50 μm under a sintering temperature of 1500 °C displayed the best properties, in which the relative density, thermal conductivity and electrical conductivity were 97.04 %, 228 W⋅m−1⋅K−1 and 46.5 % IACS, respectively. [ABSTRACT FROM AUTHOR]

Marine organisms have attracted considerable attention in recent years. In this study, peptides with osteogenic activity from Pinctada martensii were isolated and identified. Additionally, the effects of the hydrolysates on MC3T3-E1 cell proliferation and differentiation were evaluated using the MTT and alkaline phosphatase (ALP) assays, respectively. First, trypsin, pancreatin, and neutral protease were used to hydrolyse the intact shellfish. The hydrolysates with the greatest effects on osteoblast proliferation and ALP activity were separated and purified. Second, fraction WP2 was isolated and purified using a Sephadex G-25 column. WP2, which had the highest osteogenic activity, increased cell growth by 48.57 ± 0.05% and ALP activity by 6.27 ± 0.07 mU. Finally, four novel peptides were identified in WP2 (FDNEGKGKLPEEY, IVLDSGDGVTH, IVLDSGDGVSH, and SSENSDLQRQ) by Orbitrap Fusion Lumos Tribrid orbital liquid chromatography-mass spectrometry. Our findings revealed that P. martensii contains peptides with potential osteogenic activity. [ABSTRACT FROM AUTHOR]

The preparation of a family of wide-band-gap ternary oxide ferromagnetic semiconductor films with high transition metal concentration is presented. The wide gap oxide ferromagnetic semiconductors with controllable spin-polarized electrical transport could find significant application in spintronics devices as a spin injection source.

[Ge.sub.1-x][Mn.sub.x]/Ge single-crystal heterojunction diodes with p-type [Ge.sub.1-x][Mn.sub.x] ferromagnetic semiconductor are grown on Ge substrates of p-type, n-type and intrinsic semiconductors by using molecular beam epitaxy. The I-V curve of the p-[Ge.sub.0.95][Mn.sub.0.05]/intrinsic-Ge diode is tuned by a magnetic field, which is shown by a large positive magnetoresistance.

Abstract Background A variety of complex drug regimens are offered to kidney transplant recipients after transplantation. This study aimed to evaluate the behavioral and physiological outcomes of pharmaceutical care in this population. Methods A cross-sectional prospective study was conducted, which collected and categorized kidney transplant recipients according to pharmaceutical care. In the IR group, patients had received irregular pharmaceutical care after transplantation, and in the RE group, patients had received regular intervention. Intervention included face-to-face interview, checkup for laboratory examinations, discovery of drug-related problems, and pharmaceutical consultation. Baseline knowledge for self-care was tested for patients in both groups. Correct concepts and medication guidance were consistently provided to enable patients to understand the importance of rejection prevention and knowledge for medication and renal care after transplantation. After 12 months, the same test was used to evaluate the outcomes for pharmaceutical care and a satisfaction questionnaire was used to assess for pharmacy service. Results The study results revealed that patients in the RE group possessed better knowledge for self-care (P <.001); however, the differences at 12 months became insignificant (P =.72) after patients in the IR group had also received routine pharmaceutical care. Besides, serum creatinine level of the RE patients was stable without significant variation (P =.93), but it demonstrated a rising trend in IR patients (P <.01). Patients were greatly satisfactory with the intervention. Conclusions A consistent post-transplantation pharmaceutical care service is effective to substantially improve knowledge of post-transplantation self-care. Pharmaceutical care should be started as early as possible during the pre-transplant period and continue in a long-term follow-up. Highlights • A consistent pharmaceutical care service is effective to improve self-care knowledge. • Allograft function might be impaired in the beginning of the post-transplantation period. • Pharmaceutical care should be started as early as possible after transplantation. • Pharmaceutical care should continue in a long-term follow-up. [ABSTRACT FROM AUTHOR]

Abstract: Ascites sometimes occurs as a result of technical complications of transplant surgery or other medical reasons, including hepatic, cardiac, or oncologic pathology. Renal vein stenosis after renal transplant resulting in transudative ascites is rare; thus there are few if any data on such cases. Stent implantation seems to be a safe and elective approach to treatment of this rare condition. We present the case of a 22-year-old woman in whom massive ascites developed 33 months after renal transplantation. After the analysis of the ascites fluid and exclusion of transplant artery stenosis, graft rejection, infection, portal hypertension, and other possible etiologies, the final diagnosis of graft renal vein stenosis with transudative ascites derived from the graft was made based on imaging studies, including Doppler ultrasonography and computed tomography. The patient underwent angiographic stent placement, and the ascites markedly improved after the procedure. Renal vein stenosis complicated with ascites after renal transplantation is highly unusual; the patient's response to angiographic stent placement was beneficial, with satisfactory resolution of the blockage and ascites. [Copyright &y& Elsevier]