Search

A cross-sectional study in type 2 diabetic patients to evaluate the involvement of central and peripheral retina in the initial stages of diabetic retinopathy. The results indicate that diabetic eyes with visible lesions only in the peripheral retina may be associated with a milder form of the disease.

A traça-da-uva, Lobesia botrana, é praga-chave da vinha na Região Demarcada do Douro (RDD). A sua importância económica, a par da necessidade de reduzir o uso de inseticidas de síntese na vinha, conferem relevância ao desenvolvimento de estratégias de proteção contra a praga, alternativas aos meios químicos. Incluem-se nestas estratégias, a seleção das castas, as medidas culturais e a confusão sexual. O seu adequado uso obriga a um aprofundado conhecimento do comportamento do inseto em relação a diversos parâmetros biológicos. Com o presente trabalho, pretendeu-se, através da análise de dados recolhidos entre 2000 e 2019, estudar a influência, na intensidade do ataque de L. botrana, na RDD, da sub-região, ano, geração e casta. Os resultados mostraram que, a intensidade do ataque da praga: i) foi, em geral, inferior no Douro Superior, comparativamente, quer ao Cima Corgo quer ao Baixo Corgo; ii) diferiu entre anos, na dependência das condições climáticas, mas tendencialmente diminuiu ao longo dos anos; iii) na primeira geração, em geral manteve-se em valores inferiores ao nível económico de ataque, enquanto nas restantes gerações se situou entre os limites estabelecidos para o mesmo (i.e. 1 – 10% cachos atacados); iv) as castas ‘Touriga Franca’, no caso das castas tintas, e ‘Malvasia Fina’, no caso das castas brancas foram, de entre as estudadas, as tendencialmente mais atacadas.

Background/AimsRetinopathy of prematurity (ROP) is currently diagnosed through repeated eye examinations to find the low percentage of infants that fulfil treatment criteria to reduce vision loss. A prediction model for severe ROP requiring treatment that might sensitively and specifically identify infants that develop severe ROP, DIGIROP-Birth, was developed using birth characteristics. DIGIROP-Screen additionally incorporates first signs of ROP in different models over time. The aim was to validate DIGIROP-Birth, DIGIROP-Screen and their decision support tool on a contemporary Swedish cohort.MethodsData were retrieved from the Swedish national registry for ROP (2018–2019) and two Swedish regions (2020), including 1082 infants born at gestational age (GA) 24 to <31 weeks. The predictors were GA at birth, sex, standardised birth weight and age at the first sign of ROP. The outcome was ROP treatment. Sensitivity, specificity and area under the receiver operating characteristic curve (AUC) with 95% CI were described.ResultsFor DIGIROP-Birth, the AUC was 0.93 (95% CI 0.90 to 0.95); for DIGIROP-Screen, it ranged between 0.93 and 0.97. The specificity was 49.9% (95% CI 46.7 to 53.0) and the sensitivity was 96.5% (95% CI 87.9 to 99.6) for the tool applied at birth. For DIGIROP-Screen, the cumulative specificity ranged between 50.0% and 78.7%. One infant with Beckwith-Wiedemann syndrome who fulfilled criteria for ROP treatment and had no missed/incomplete examinations was incorrectly flagged as not needing screening.ConclusionsDIGIROP-Birth and DIGIROP-Screen showed high predictive ability in a contemporary Swedish cohort. At birth, 50% of the infants born at 24 to <31 weeks of gestation were predicted to have low risk of severe ROP and could potentially be released from ROP screening examinations. All routinely screened treated infants, excluding those screened for clinical indications of severe illness, were correctly flagged as needing ROP screening.

Purpose To study the correlation among cataract grading system by Scheimpflug imaging (Oculus Pentacam®Nucleus Grading System [PNS]), effective phaco time (EPT), and surgical time (ST) using peristaltic and venturi pumps on the Whitestar Signature Phaco System (Abbott Medical Optics, Inc., Santa Ana, California, USA).Methods Patients scheduled to have bimanual microincision phacoemulsification by the same surgeon (T.F.) had Pentacam®Scheimpflug assessment using PNS and were randomly distributed into 2 groups. In group 1, surgery was performed using peristaltic pump, and in group 2, using venturi pump. Parameters assessed in both groups included EPT and ST.Results Sixty eyes that had uneventful clear cornea phacoemulsification with implantation of foldable intraocular lens (IOL) were evaluated, 30 in each group. The EPT was statistically superior with higher nuclear density grades for both groups 1 and 2 (group 1 Spearman R = 0.739, p<0.001; group 2 Spearman R = 0.924, p<0.001). The ST statistically increased with nucleus density for both groups 1 and 2 (group 1 Spearman R = 0.620, p<0.001; group 2 Spearman R = 0.643, p<0.001). Group 2 presented statistically significant reduction on median ST compared with group 1 for nucleus grading 2, 3, 4, and 5.Conclusions The PNS is an objective and reproducible method of grading nuclear cataract density and had a correlation with EPT. Peristaltic and venturi pumps in Signature Phaco System were similar in EPT but venturi pump reduced the median ST in nucleus with higher PNS, without repercussion on complications or anterior chamber stability.