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Researchers Filatov and Liu have submitted a patent application for a system and method aimed at detecting, enumerating, or extracting microorganisms in a sample, particularly focusing on Salmonella. The method involves immunomagnetic separation, plating, and incubating bead-bound cells to generate colonies for detection. This innovative approach seeks to streamline the process of identifying and subtyping Salmonella, potentially revolutionizing current culture-based techniques in bacterial pathogen testing. The patent application, assigned to Microsensor Labs LLC, highlights the ongoing efforts to enhance food safety and combat foodborne illnesses caused by pathogens like Salmonella. [Extracted from the article]

Researchers have submitted a patent application for a therapeutic platform aimed at addressing autoimmune diseases, particularly psoriasis. The platform involves isolating immune cells from psoriatic tissue samples using various techniques without altering their biochemical profile significantly. The patent application outlines methods for preparing immune cell samples, detecting markers associated with immune cells, and identifying antigens that stimulate immune responses. The inventors aim to use this platform to develop treatments for autoimmune disorders like psoriasis, type 1 diabetes mellitus, rheumatoid arthritis, and multiple sclerosis. [Extracted from the article]

A study conducted at Nanjing Normal University in China focused on the enrichment of trace enrofloxacin antibiotics in water using immunomagnetic separation (IMS) with magnetic nanoparticles (MNPs). The research aimed to address the potential risks posed by the presence of antibiotics in water, including the development of drug-resistant bacterial strains. The study successfully achieved efficient enrichment and isolation of enrofloxacin, with a high separation efficiency of 97.68% through IMS. However, the research also highlighted the importance of controlling elution time and temperature to minimize the risk of degradation products with higher toxicity. [Extracted from the article]

A study conducted at Semmelweis University in Budapest, Hungary, investigated the impact of immunomagnetic separation on the immunophenotype and viability of plasma cells in plasma cell disorders. The research focused on the expression patterns of various surface markers before and after magnetic isolation using samples from patients with plasma cell disorders. The study found that while some markers were slightly influenced, the immunophenotype of the cells remained unchanged, indicating that magnetic isolation can be a reliable option for plasma cell enrichment. The findings suggest that further validation of the immunophenotype of plasma cells should be conducted after separation, especially if marker intensities are crucial for subsequent experiments. [Extracted from the article]

A recent study from Oregon State University evaluated molecular-based methods for detecting and quantifying Cryptosporidium in wastewater. The research highlighted the challenges in clinical surveillance of cryptosporidiosis and the potential of wastewater surveillance for identifying the parasite at the population level. Various concentration methods, DNA extraction techniques, and genetic detection assays were compared, with centrifugation showing the highest oocyst recovery percentages. The study concluded that the 18S rRNA assay had a lower detection limit and broader range of detection for Cryptosporidium spp. compared to the oocyst wall protein assay. [Extracted from the article]

A study conducted by Jiangsu University in China has developed an ultrasensitive method for detecting Escherichia coli O157:H7, a pathogen commonly found in food. The method combines immunomagnetic separation and labeled surface-enhanced Raman scattering (SERS) to achieve high selectivity in pathogen monitoring. The researchers used monoclonal antibodies and aptamers to identify and separate the bacteria, and a plasmonic nanostructure with embedded Raman tags for detection. The method showed good linearity and a limit of detection of 2 CFU/mL, making it a promising tool for on-site food pathogenic bacterial detection. The research has been peer-reviewed and published in the Journal of Agricultural and Food Chemistry. [Extracted from the article]

The article focuses on a patent application for a new method to genetically modify human hepatocytes to improve their transplantation success. Topics include enhancing the engraftment of hepatocytes by disrupting major histocompatibility complex (MHC) genes, using CRISPR-based technology for gene editing, and addressing issues related to the limited supply and long-term acceptance of hepatocyte transplants.

Researchers from Hubei University in Wuhan, China have developed a colorimetric single-nanoparticle collision electrochemistry (SNCE) biosensor for the detection of MCF-7 cells, a type of cancer cell. The biosensor combines gold ultramicroelectrodes modified with a sulfide layer, liposome encapsulation-release strategy, and immunomagnetic separation to capture and separate the cells. The biosensor was able to detect MCF-7 cells at a low concentration of 5 cells/mL and was used to analyze peripheral blood samples from cancer patients. The research provides two analysis forms for more accurate detection outcomes. [Extracted from the article]

Researchers at Taiyuan University of Technology in Shanxi, China have developed an integrated magnetic separation enzyme-linked colorimetric sensing platform for the field detection of Escherichia coli O157:H7 (E. coli O157:H7) in food. The platform utilizes antibody-modified magnetic nanoparticles and detection antibody/horseradish peroxidase co-functionalized gold nanoparticles for targeted enrichment and colorimetric assay of E. coli O157:H7. The researchers constructed a highly integrated optical device that allows for in situ magnetic separation and imaging of microplates containing E. coli O157:H7 using a smartphone. The biosensor demonstrated high sensitivity, short detection time, and good anti-interference performance, making it a promising tool for the detection of foodborne pathogens. [Extracted from the article]

A recent study conducted by researchers from the Shanghai Academy of Agricultural Sciences in China compared two magnetic separation methods for detecting Staphylococcus aureus in milk samples. The first method used amino-modified silica magnetic particles (ASMPs) for DNA separation, while the second method utilized pig IgG-labeled magnetic beads (IgG-MBs) for cell separation. Both methods demonstrated high specificity and robustness against background bacteria interference, but neither method effectively distinguished between live and dead bacteria. The study contributes to the optimization of magnetic separation techniques for the molecular detection of foodborne pathogens, highlighting the potential of culture-independent detection methods. [Extracted from the article]

This article discusses a research study on Escherichia coli O157:H7, a strain of bacteria that can cause foodborne illnesses. The study focuses on two patients with acute gastroenteritis who tested positive for Shiga toxin-producing E. coli (STEC). The researchers used immunomagnetic separation (IMS) to isolate the STEC strains from the patients' stools, as routine culture methods failed. The strains were identified as O166:H15 STEC and were found to carry the Shiga toxin 2 encoding gene. The study highlights the challenges in isolating this strain and emphasizes the importance of characterizing virulence genes in these isolates. [Extracted from the article]

Researchers from the Technical University of Munich (TUM) have developed a culture-independent method for quantifying Legionella pneumophila, the bacteria responsible for Legionnaires' disease, in evaporative cooling systems (ECS). The traditional cultivation method for detecting Legionella spp. in water samples is time-consuming and may underestimate the total count of viable L. pneumophila. The researchers used cartridge-based immunomagnetic separation (IMS) coupled with flow cytometry (FCM) to achieve rapid and accurate quantification of L. pneumophila in ECS samples. This culture-independent method showed positive results for L. pneumophila, while cultivation did not. The study concludes that IMS-FCM is a suitable and efficient method for monitoring L. pneumophila in ECS. [Extracted from the article]

A report from Nanjing Medical University in China discusses a new microfluidic platform that integrates optical detection to rapidly detect the presence of Pseudomonas aeruginosa and Escherichia coli, two types of Gram-negative bacteria. The platform uses immunomagnetic separation to isolate the pathogens from a testing sample, and then passes the separated sample through a microfluidic chip embedded with fiber optics and photosensors. The scattered light signals from the passing magnetic beads are collected and analyzed using a calibration model, resulting in high classification accuracy for both P. aeruginosa and E. coli. The technique has a 15-minute detection time and does not require complex sample preparation or laboratory tools. [Extracted from the article]

Researchers at Autonomous University Barcelona have developed a new method for detecting Mycobacterium fortuitum, a type of Gram-Positive Bacteria. The method involves a combination of filtration and direct immunomagnetic separation to isolate the bacteria, which is then analyzed using electrochemical magneto immunosensing in a handheld device. This approach offers a simplified and highly sensitive alternative to traditional methods of culturing and isolating mycobacteria, with a detection limit of 5 CFU mL-1 in hemodialysis water. The research has been peer-reviewed and funded by the Spanish Government, Generalitat de Catalunya, and Ministry of Universities. [Extracted from the article]

A recent report from Yerevan, Armenia highlights the need for more data on parasite contamination of water sources in the region. The study focused on the presence of intestinal protozoan parasites in raw water samples and sediment. The results indicate significant contamination of these water sources, emphasizing the importance of further targeted studies and data collection on host infections in catchment areas. This research provides valuable insights into the prevalence of food and waterborne parasitology in Armenia, an area where data is currently limited. [Extracted from the article]

A recent study conducted by Atma Jaya Catholic University in Jakarta, Indonesia, explores the use of magnetic nanomaterials (MNMs) in the fabrication of lateral flow assays (LFAs) to improve food safety analysis. LFAs are portable sensing platforms commonly used in biosensors. The study suggests that substituting gold nanoparticles (AuNPs) with MNMs can enhance the performance of LFAs, particularly in the presence of NaCl in real samples. MNMs not only enable quantitative measurements but also act as immunomagnetic separation agents. The research highlights the potential of MNMs in improving the limit of detection (LOD) of analytes in food safety analysis. [Extracted from the article]

Keywords: Garching; Germany; Europe; Cytometry; Gammaproteobacteria; Gram-Negative Aerobic Bacteria; Gram-Negative Aerobic Rods and Cocci; Gram-Negative Bacteria; Health and Medicine; Legionella pneumophila; Legionellaceae; Legionellosis; Legionnaires' Disease; Lung Diseases and Conditions; Proteobacteria EN Garching Germany Europe Cytometry Gammaproteobacteria Gram-Negative Aerobic Bacteria Gram-Negative Aerobic Rods and Cocci Gram-Negative Bacteria Health and Medicine Legionella pneumophila Legionellaceae Legionellosis Legionnaires' Disease Lung Diseases and Conditions Proteobacteria 398 398 1 07/17/23 20230721 NES 230721 2023 JUL 18 (NewsRx) -- By a News Reporter-Staff News Editor at TB & Outbreaks Week -- Current study results on Lung Diseases and Conditions - Legionnaires' Disease have been published. Garching, Germany, Europe, Cytometry, Gammaproteobacteria, Gram-Negative Aerobic Bacteria, Gram-Negative Aerobic Rods and Cocci, Gram-Negative Bacteria, Health and Medicine, Legionella pneumophila, Legionellaceae, Legionellosis, Legionnaires' Disease, Lung Diseases and Conditions, Proteobacteria. [Extracted from the article]

Keywords for this news article include: Lyon, France, Europe, Genomics and Genetics, Bacterial Toxins, Biological Factors, Enterotoxins, Shiga Toxins, University of Lyon. Lyon, France, Europe, Genomics and Genetics, Bacterial Toxins, Biological Factors, Enterotoxins, Shiga Toxins Keywords: Lyon; France; Europe; Genomics and Genetics; Bacterial Toxins; Biological Factors; Enterotoxins; Shiga Toxins EN Lyon France Europe Genomics and Genetics Bacterial Toxins Biological Factors Enterotoxins Shiga Toxins 1943 1943 1 07/17/23 20230721 NES 230721 2023 JUL 21 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- Research findings on Genomics and Genetics are discussed in a new report. [Extracted from the article]

Keywords: Shaanxi; People's Republic of China; Asia; Emerging Technologies; Enterobacteriaceae; Foodborne Diseases and Conditions; Gammaproteobacteria; Gram-Negative Bacteria; Gram-Negative Facultatively Anaerobic Rods; Nanobodies; Nanotechnology; Proteobacteria; Salmonella; Salmonella enterica; Salmonella enteritidis EN Shaanxi People's Republic of China Asia Emerging Technologies Enterobacteriaceae Foodborne Diseases and Conditions Gammaproteobacteria Gram-Negative Bacteria Gram-Negative Facultatively Anaerobic Rods Nanobodies Nanotechnology Proteobacteria Salmonella Salmonella enterica Salmonella enteritidis 170 170 1 06/12/23 20230615 NES 230615 2023 JUN 15 (NewsRx) -- By a News Reporter-Staff News Editor at Food Weekly News -- New research on Gram-Negative Bacteria - Salmonella enteritidis is the subject of a report. Keywords for this news article include: Asia, Shaanxi, Nanobodies, Nanotechnology, Enterobacteriaceae, Gammaproteobacteria, Salmonella enterica, Emerging Technologies, Gram-Negative Bacteria, Salmonella enteritidis, People's Republic of China, Foodborne Diseases and Conditions, Gram-Negative Facultatively Anaerobic Rods. [Extracted from the article]

Keywords: Ahvaz; Iran; Asia; Diseases and Conditions; Enterobacteriaceae; Foodborne Diseases and Conditions; Gammaproteobacteria; Gram-Negative Bacteria; Gram-Negative Facultatively Anaerobic Rods; Proteobacteria; Risk and Prevention; Salmonella; Salmonella enterica; Salmonella typhimurium; Salmonellosis EN Ahvaz Iran Asia Diseases and Conditions Enterobacteriaceae Foodborne Diseases and Conditions Gammaproteobacteria Gram-Negative Bacteria Gram-Negative Facultatively Anaerobic Rods Proteobacteria Risk and Prevention Salmonella Salmonella enterica Salmonella typhimurium Salmonellosis 175 175 1 05/15/23 20230518 NES 230518 2023 MAY 18 (NewsRx) -- By a News Reporter-Staff News Editor at Food Weekly News -- New research on Gram-Negative Bacteria - Salmonella typhimurium is the subject of a report. Ahvaz, Iran, Asia, Diseases and Conditions, Enterobacteriaceae, Foodborne Diseases and Conditions, Gammaproteobacteria, Gram-Negative Bacteria, Gram-Negative Facultatively Anaerobic Rods, Proteobacteria, Risk and Prevention, Salmonella, Salmonella enterica, Salmonella typhimurium, Salmonellosis. [Extracted from the article]

Keywords: Chongqing; People's Republic of China; Asia; Fusobacterium; Fusobacterium nucleatum; Gram-Negative Anaerobic Bacteria; Gram-Negative Bacteria; Health and Medicine EN Chongqing People's Republic of China Asia Fusobacterium Fusobacterium nucleatum Gram-Negative Anaerobic Bacteria Gram-Negative Bacteria Health and Medicine 3336 3336 1 03/23/23 20230317 NES 230317 2023 MAR 17 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Gram-Negative Bacteria - Fusobacterium nucleatum have been published. Chongqing, People's Republic of China, Asia, Fusobacterium, Fusobacterium nucleatum, Gram-Negative Anaerobic Bacteria, Gram-Negative Bacteria, Health and Medicine. [Extracted from the article]

Keywords: Giresun; Turkey; Eurasia; Bacillales; Foodborne Diseases and Conditions; Gram-Positive Asporogenous Rods; Gram-Positive Bacteria; Gram-Positive Rods; Listeria; Listeria monocytogenes; Regular Gram-Positive Asporogenous Rods; Risk and Prevention EN Giresun Turkey Eurasia Bacillales Foodborne Diseases and Conditions Gram-Positive Asporogenous Rods Gram-Positive Bacteria Gram-Positive Rods Listeria Listeria monocytogenes Regular Gram-Positive Asporogenous Rods Risk and Prevention 2023 MAR 2 (NewsRx) -- By a News Reporter-Staff News Editor at Food Weekly News -- A new study on Gram-Positive Bacteria - Listeria monocytogenes is now available. Giresun, Turkey, Eurasia, Bacillales, Foodborne Diseases and Conditions, Gram-Positive Asporogenous Rods, Gram-Positive Bacteria, Gram-Positive Rods, Listeria, Listeria monocytogenes, Regular Gram-Positive Asporogenous Rods, Risk and Prevention. [Extracted from the article]

Heilongjiang, People's Republic of China, Asia, Biomarkers, Cancer, Diagnostics and Screening, Esophageal Cancer, Gastroenterology, Health and Medicine, Oncology, Stem Cell Research Keywords: Heilongjiang; People's Republic of China; Asia; Biomarkers; Cancer; Diagnostics and Screening; Esophageal Cancer; Gastroenterology; Health and Medicine; Oncology; Stem Cell Research EN Heilongjiang People's Republic of China Asia Biomarkers Cancer Diagnostics and Screening Esophageal Cancer Gastroenterology Health and Medicine Oncology Stem Cell Research 2023 FEB 7 (NewsRx) -- By a News Reporter-Staff News Editor at Stem Cell Week -- Investigators publish new report on Oncology - Esophageal Cancer. [Extracted from the article]

Herein, due to the controllablerelease amplification strategy of liposomes, a reliable androbust single-particle collision electrochemical (SPCE) biosensorwas constructed for H9N2 avian influenza virus (H9N2 AIV)detection by combining liposome encapsulation-release strategywith immunomagnetic separation." Our news editors obtained a quote from the research from HubeiUniversity, "The liposomes modified with biotin and loaded withplatinum nanoparticles (Pt NPs) were used as signal probes forthe first time. [Extracted from the article]

The article focuses on the immunomagnetic separation technique invented to determine allergy-provoking proteins by Bi Hongyan of Shanghai Ocean University of China and colleagues and published in the "Journal of Agriculture and Food Chemistry" in 2021. Topics discussed include the use of antibodies from people with allergies in the technique, role of mass spectrometry and liquid chromatography in studying the antibodies, and potential of the technique to identify lethal allergens.

The article informs that RapidChek CONFIRM nonO157 STEC Immunomagnetic Separation (IMS) test kit from the company SDIX has been reviewed by the U.S. Department of Agriculture (USDA) and has been listed in the USDA Microbiological Laboratory Guidebook (MLG) 5B.02 as the IMS reagents to be used in E. coli testing. SDIX is a biotechnology company that develops antigens, antibodies and assays for the pharmaceutical, biotechnology and food safety markets.

The article offers brief information on Captivate O45 immunomagnetic separation (IMS) product from Lab M Ltd.