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A study conducted at Children's Hospital Colorado focused on the complications of intrathecal baclofen therapy in children and young adults. The research analyzed patient demographics, improvements in tone, and clinical complications associated with ITB therapy. Complications such as catheter issues and pseudomeningoceles were common, with newer catheter models showing fewer complications. The study concluded that ventriculoperitoneal shunts and gastrostomy tubes did not significantly increase complication rates, and patients with preexisting VP shunts showed greater improvement in MAS scores. [Extracted from the article]

A recent study from Southern Medical University in Guangzhou, China, explores the use of hypophysectomy, pituitary neuroadenolysis, and pituitary radiosurgery as alternative treatments for refractory cancer pain. The research highlights the historical evolution, clinical outcomes, and hypothesized mechanisms of these procedures, emphasizing the potential for improved palliative care in oncology. Despite promising results, unresolved issues such as optimal radiation dose and precise mechanisms limit widespread adoption, underscoring the need for further research in this area. [Extracted from the article]

Researchers at the University of California San Diego (UCSD) conducted a study on a case involving a 66-year-old woman with persistent spinal pain syndrome who developed an intrathecal mass after receiving intrathecal infusions of sufentanil for approximately ten years. The mass, composed mainly of fibroblasts and inflammatory cells, was surgically removed. This case report is the first to document sufentanil causing this complication, highlighting the need for further research on intrathecal catheter tip-associated mass formation. The study was published in Neuromodulation: Technology at the Neural Interface and can be accessed online for more information. [Extracted from the article]

A patient in their 70s with advanced esophageal cancer experienced lack of efficacy with oxycodone and developed vomiting and urinary retention with morphine treatment for pain. Despite severe pain in the upper chest and other areas, the patient's condition deteriorated, leading to the implantation of an intrathecal morphine delivery system for pain relief. After adjusting the morphine concentration and pumping speed, the patient experienced relief from vomiting and urinary retention, ultimately passing away three months post-implantation due to advanced esophageal cancer. [Extracted from the article]

A clinical trial, NCT06552000, is being conducted to study the effects of Tumor Treatment Fields (TTFields) on patients with stage I-IIIA Non-Small Cell Lung Cancer (NSCLC) who are undergoing resection. TTFields is a non-invasive treatment that uses low-intensity electrical fields to treat cancer. The trial aims to assess the safety of administering TTFields before lung cancer resection and determine its effect on the expression of Fanconi anemia pathway-associated genes in NSCLC. The trial is not yet recruiting and aims to enroll 18 participants, with a primary completion date of December 1, 2027. The study is being conducted in the United States and is sponsored by NovoCure Ltd, with Dr. John Waters from UT Southwestern Medical Center as the principal investigator. [Extracted from the article]

A 38-year-old man with signet ring cell adenocarcinoma (SRCA) exhibited lack of efficacy during treatment with oxaliplatin, fluorouracil, and capecitabine. The patient had a significant medical history of deep vein thrombosis (DVT), alcohol use, and tobacco use. He initially presented with symptoms of recurrent DVT and was later diagnosed with gastric SRCA. Despite receiving chemotherapy for 10 months, the patient developed leptomeningeal metastasis and eventually passed away. [Extracted from the article]

A case report published in Reactions Weekly describes the development of prolonged pancytopenia in a 2-month-old girl undergoing treatment for aleukaemic leukaemia cutis. The girl initially presented with a blueberry muffin rash and underwent biopsy and bone marrow examination. Despite an initial misdiagnosis, a final diagnosis of juvenile xanthogranuloma (JXG) was made. The pancytopenia improved after chemotherapy was discontinued and the nodules regressed over time. [Extracted from the article]

Researchers at the University of Ulsan College of Medicine in South Korea have conducted a study on the relationship between neuropathic pain and the expression levels of CREB-binding protein (CBP) and methyl-CpG-binding protein 2 (MeCP2) in a rat model with spared nerve injury (SNI). The study found that SNI led to an increase in CBP levels and a decrease in MeCP2 levels in certain areas of the rats' spinal cord and dorsal root ganglion. The researchers also discovered that intrathecal injection of CBP small interference RNA (siRNA) inhibited mechanical allodynia induced by SNI. The study suggests that CBP and MeCP2 may play a role in the development of neuropathic pain following peripheral nerve injury. [Extracted from the article]

A new report discusses research on the use of intrathecal dexamethasone during subarachnoid block (SAB) for various surgical procedures. The research aimed to evaluate the effectiveness and safety of using intrathecal dexamethasone as an adjuvant to spinal local anesthetics. The meta-analysis of 18 studies found that the addition of intrathecal dexamethasone effectively prolonged the duration of sensory blockade, two-segment regression time, and first rescue analgesic time. It also showed lower risk ratios for SAB-induced hypotension and nausea/vomiting. However, further studies are needed to draw meaningful conclusions on its safety profile. [Extracted from the article]

A recent study conducted in Chicago, Illinois, explored the safety and efficacy of using a cervical catheter tip for the continuous intrathecal baclofen (ITB) treatment of hypertonia in children. Traditionally, the cervical tip location has been avoided due to concerns of hypoventilation and pneumonia, but this study found that these complications were not reliably proven. The study included 25 patients, and the results showed that the cervical catheter tip location for ITB is safe and effective in controlling tone. However, larger studies with longer follow-up are needed to determine upper-limit dosing safety and long-term functional benefits. [Extracted from the article]

Researchers from Niigata University Graduate School of Medical and Dental Sciences have conducted a study on the analgesic effects of Yokukansan, a traditional Japanese medicine, on acute postoperative pain. The study found that oral administration of Yokukansan increased the pain threshold in mice with postoperative pain. The researchers suggest that Yokukansan acts as an agonist at the 5-HT1A receptor, a serotonin receptor, to produce analgesia. This research provides insight into the potential effectiveness of Yokukansan in treating postoperative pain. [Extracted from the article]

A new report discusses research findings on prostatitis, a condition characterized by inflammation of the prostate gland. The study, conducted by researchers at Nanchang University in China, focused on the role of spinal cord glial cells in relation to pain. The researchers found that intrathecal injection of BNP (brain natriuretic peptide) can down-regulate the expression of certain proteins associated with chronic pain in rats with nonbacterial prostatitis. This research provides insights into potential therapeutic approaches for managing pain in individuals with prostatitis. [Extracted from the article]

A recent study conducted by the All India Institute of Medical Sciences (AIIMS) compared the use of intrathecal morphine and bupivacaine with caudal morphine and bupivacaine in pediatric patients undergoing lower abdominal surgeries. The study found that intrathecal morphine and bupivacaine resulted in longer duration of analgesia, lower analgesic consumption, prevention of surgical-stress-related elevation of serum cortisol, and improved parent satisfaction compared to caudal morphine with bupivacaine. The research concluded that intrathecal morphine and bupivacaine is more effective in providing postoperative analgesia in pediatric patients. [Extracted from the article]

This document provides information about a clinical trial that is currently recruiting participants. The trial aims to compare the effectiveness of two different drugs, chloroprocaine and ropivacaine, for spinal anesthesia during cesarean section surgeries. The trial is open to adult female participants who meet certain criteria, and the estimated completion date is January 10, 2026. The document also includes contact information for the primary investigator and the location of the trial, which is in Greece. [Extracted from the article]

The article discusses a clinical trial in Taiwan, NCT06344169, that is investigating a new pain management strategy for patients who have had a cesarean section. Inadequate pain management after surgery can cause physical and psychological distress. The trial will test the use of a prodrug called Naldebain(R), which releases an analgesic called nalbuphine. The goal is to provide long-lasting pain relief and prevent chronic post-surgical pain. The trial will compare the effectiveness of Naldebain(R) to the standard treatment of intrathecal morphine injection. The study aims to enroll 120 participants and is estimated to be completed by June 2026. [Extracted from the article]

A recent study conducted by researchers at the University College of Medical Sciences and GTB Hospital in Delhi, India, aimed to determine the minimum effective dose of intrathecal hyperbaric bupivacaine for cesarean section with and without prophylactic norepinephrine infusion. The study found that the use of prophylactic norepinephrine during cesarean delivery does not require adjustment of intrathecal hyperbaric bupivacaine. The researchers also observed that the block characteristics and neonatal outcomes were similar between the groups, but the umbilical artery base excess was greater in the norepinephrine group. This information may be useful for healthcare professionals involved in cesarean section procedures. [Extracted from the article]

A pilot study discussed in Medical Devices & Surgical Technology Week explores the use of ultrasound as a guide for lumbar intrathecal injection in rats. Lumbar intrathecal administration is a method of drug delivery into the central nervous system, particularly for treating chronic pain in rat models. The study found that ultrasound-guided acute needle puncture intrathecal administration was successful in six male Sprague Dawley rat cadavers, confirming the usefulness of ultrasound as a tool for this procedure. However, it should be noted that this preprint has not yet undergone peer review. [Extracted from the article]

This document provides information about a clinical trial conducted by Ain Shams University. The trial aims to compare the effectiveness of two drugs, fentanyl and dexmedetomidine, as adjuvants to intrathecal bupivacaine in patients undergoing spinal anesthesia for cesarean section. The trial is not yet recruiting and is expected to be completed by November 2024. The eligibility criteria include female patients aged 20-35 years who are scheduled for cesarean section under spinal anesthesia. The study will be monitored by a data monitoring committee, and the data will be shared once the study is completed. [Extracted from the article]

A report from Georgetown University discusses the challenges of treating neurological disorders and the potential for a new method of therapeutic delivery to the brain. The researchers propose using the ventricular system as an anatomical pathway for delivering therapies to the deep brain. They have tested a narrow self-expanding electrical recording device on human brain samples and found that it can navigate the ventricular system. While more research is needed, this study identifies a minimally invasive and effective pathway for delivering therapeutic and diagnostic tools to the brain. [Extracted from the article]

A study conducted by researchers from Binzhou Medical University compared the effects of intrathecal dexmedetomidine (administered through the spinal cord) and intravenous infusion on subarachnoid blockade during knee arthroscopy procedures. The study involved 90 patients who were randomized into intrathecal, intravenous, and control groups. The results showed that intrathecal administration of dexmedetomidine prolonged the duration of analgesia and accelerated the onset of sensory-motor blockade compared to intravenous infusion. No adverse events or hemodynamic instability were observed. The study was registered with the Chinese Clinical Trial Center. [Extracted from the article]

A patent has been issued for a therapy-specific, pre-programmed auto-injection device developed by Alcyone Therapeutics Inc. The device is designed to deliver drugs to patients in a controlled manner, addressing the challenges associated with manual drug delivery. It includes a housing, multiple syringes, actuators, and a controller. The device can be programmed with an infusion and aspiration protocol and can be adapted for different anatomical sites and specific treatments. The patent also mentions the use of the device for delivering antisense oligonucleotides and other therapeutic substances. [Extracted from the article]

Alcyone Therapeutics has announced the first patient implanted in the PIERRE clinical study, which aims to evaluate the safety and performance of the ThecaFlex DRx System for the delivery of SPINRAZA in spinal muscular atrophy (SMA) patients. The ThecaFlex device has the potential to reduce the need for lumbar punctures and improve the overall administration experience of SPINRAZA. The study will enroll up to 90 patients in two stages and is part of a collaboration between Alcyone and Biogen Inc. ThecaFlex has received CE Mark in Europe and IDE approval from the FDA for clinical investigation. [Extracted from the article]

A recent study conducted at Conquest Hospital examined the use of ondansetron for the prevention of pruritus (itching) in women undergoing cesarean delivery with intrathecal opioid. The researchers conducted a systematic review of 23 randomized controlled trials involving 2,586 patients. The results showed that patients who received ondansetron had a significantly lower incidence of pruritus compared to the control group. However, the quality of evidence was assessed as low, and further high-quality studies are needed to confirm these findings. [Extracted from the article]

A recent study conducted at Sun Yat-sen University Cancer Center in Guangzhou, China, explored the treatment of leptomeningeal metastasis (LM) in patients with advanced nasopharyngeal carcinoma (NPC). The study focused on a 38-year-old man who received first-line chemoimmunotherapy for his condition. Despite initial positive response, the patient developed neurological symptoms and was diagnosed with LM. The study concluded that while immunotherapy has shown significant benefits for advanced NPC patients, it may not be effective in treating LM. Further research is needed to explore alternative treatment options such as radiation therapy and intrathecal therapy. [Extracted from the article]

A recent study conducted at Bharti Vidyapeeth Deemed University Medical College in India compared the efficacy of intrathecal buprenorphine and intrathecal fentanyl as adjuvants to hyperbaric bupivacaine in spinal anesthesia for lower segment caesarean sections (LSCS). The study found that both drugs were safe and effective as adjuvants, but intrathecal buprenorphine provided a more promising postoperative analgesic effect compared to intrathecal fentanyl. The addition of intrathecal buprenorphine also resulted in a longer duration of sensory and motor block. The study concluded that intrathecal buprenorphine is a suitable option for achieving intra/postoperative analgesia in LSCS without significant side effects. [Extracted from the article]

A recent study conducted at the Affiliated Hospital of Yangzhou University aimed to evaluate the differences in postoperative pain and recovery between patients receiving intrathecal morphine paired with low-dose bupivacaine and those administered general anesthesia exclusively for thoracoscopic surgery. The study enrolled 100 patients and found that postoperative pain scores were significantly lower in the morphine and bupivacaine group compared to the control group. Additionally, patients in the morphine and bupivacaine group had delayed analgesic requests and lower postoperative opioid use. The study concluded that intrathecal administration of morphine combined with bupivacaine effectively alleviates acute pain in patients undergoing thoracoscopic surgery. [Extracted from the article]

This document provides information about a clinical trial for the treatment of Pelizaeus-Merzbacher Disease (PMD). The trial is testing a drug called ION356, which is administered through intrathecal injection. The trial has two experimental cohorts, each receiving a different dose of ION356. The study aims to enroll 24 male participants between the ages of 2 and 17 years. The estimated completion date for the trial is June 2028. The document also includes eligibility criteria and contact information for the study. [Extracted from the article]

A recent study conducted at the University Hospital Hamburg-Eppendorf in Germany focused on meningeal neoplasms, specifically meningeal carcinomatosis, which occurs in around 5% of patients with metastatic breast cancer. The study examined various intrathecal therapy options for treating this condition, including methotrexate, liposomal cytarabine, and trastuzumab. The researchers found that intrathecal therapy has a tolerable side-effects profile and shows promising results, particularly with trastuzumab for HER2-positive primary tumors. However, more comprehensive studies comparing the efficacy and side effects of different pharmaceuticals are needed. The study emphasizes the importance of a multimodal individual therapeutic approach and considering best supportive care for patients with meningeal carcinomatosis due to its poor prognosis. [Extracted from the article]

A study conducted at King Fahad Medical City in Saudi Arabia examined the complications of intrathecal baclofen pump therapy (ITB) for the management of spasticity. The study analyzed various demographic and technical factors and found that catheter-related complications were the most common, followed by loss of efficacy and baclofen withdrawal. The study did not find significant associations between complications and gender, rehabilitation diagnosis, patients' residence, facility of ITB placement, age, distance from hospital, disease onset, ITB therapy duration, or baclofen dose. This research provides valuable insights into the complications associated with ITB treatment. [Extracted from the article]

Keywords: Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Cerebral Palsy; Chronic Brain Damage; Clinical Research; Clinical Trials and Studies; Health and Medicine EN Brain Diseases and Conditions Central Nervous System Diseases and Conditions Cerebral Palsy Chronic Brain Damage Clinical Research Clinical Trials and Studies Health and Medicine 1571 1571 1 10/03/23 20231006 NES 231006 2023 OCT 2 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Investigators publish new report on cerebral palsy. Keywords for this news article include: University of Modena and Reggio Emilia, Cerebral Palsy, Clinical Research, Health and Medicine, Chronic Brain Damage, Clinical Trials and Studies, Brain Diseases and Conditions, Central Nervous System Diseases and Conditions. [Extracted from the article]

Keywords: Winston-Salem; State:North Carolina; United States; North and Central America; Arthroplasty; Cardiovascular Diseases and Conditions; Clinical Research; Clinical Trials and Studies; Drugs and Therapies; Genitourinary Tract Agents; Health and Medicine; Hypotension; Opioids; Orthopedic Procedures; Oxytocin Therapy; Pharmaceuticals; Physical Therapy; Physical Therapy and Rehabilitation Medicine; Placebos; Surgery; Uterotonic Agents EN Winston-Salem State:North Carolina United States North and Central America Arthroplasty Cardiovascular Diseases and Conditions Clinical Research Clinical Trials and Studies Drugs and Therapies Genitourinary Tract Agents Health and Medicine Hypotension Opioids Orthopedic Procedures Oxytocin Therapy Pharmaceuticals Physical Therapy Physical Therapy and Rehabilitation Medicine Placebos Surgery Uterotonic Agents 972 972 1 10/03/23 20231006 NES 231006 2023 OCT 2 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Investigators publish new report on Opioids. Winston-Salem, State:North Carolina, United States, North and Central America, Arthroplasty, Cardiovascular Diseases and Conditions, Clinical Research, Clinical Trials and Studies, Drugs and Therapies, Genitourinary Tract Agents, Health and Medicine, Hypotension, Opioids, Orthopedic Procedures, Oxytocin Therapy, Pharmaceuticals, Physical Therapy, Physical Therapy and Rehabilitation Medicine, Placebos, Surgery, Uterotonic Agents. [Extracted from the article]

For more information on this research see: Vomiting after intrathecal chemotherapy under anesthesia in pediatric patients with hematologic cancers: A cohort study. Keywords: Recife; Brazil; South America; Anesthesia; Cancer; Chemotherapy; Clinical Research; Clinical Trials and Studies; Drugs and Therapies; Health and Medicine; Oncology; Pain Medicine; Pediatrics; Risk and Prevention EN Recife Brazil South America Anesthesia Cancer Chemotherapy Clinical Research Clinical Trials and Studies Drugs and Therapies Health and Medicine Oncology Pain Medicine Pediatrics Risk and Prevention 236 236 1 10/03/23 20231006 NES 231006 2023 OCT 7 (NewsRx) -- By a News Reporter-Staff News Editor at Pediatrics Week -- New research on Drugs and Therapies - Chemotherapy is the subject of a report. [Extracted from the article]

The top five cancers in patients receiving IDDS were lung (27.15%), colorectal (24.9%), liver (16.44%), bone (8.01%), and liver (7.99%) cancer. Keywords: Minneapolis; State:Minnesota; United States; North and Central America; Bone Research; Cancer; Drug Delivery; Drug Delivery Systems; Drugs and Therapies; Health and Medicine; Hospitals; Oncology EN Minneapolis State:Minnesota United States North and Central America Bone Research Cancer Drug Delivery Drug Delivery Systems Drugs and Therapies Health and Medicine Hospitals Oncology 982 982 1 09/25/23 20230929 NES 230929 2023 SEP 26 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- New research on Cancer is the subject of a report. [Extracted from the article]

The implantable medical pump of claim 1, wherein the at least one catheter comprises: a first catheter configured to deliver the medicament and the fluid from the medicament reservoir to the target location; and a second catheter configured to aspirate the fluid from the target location into the medicament reservoir. The implantable medical pump of claim 8, wherein the processor is configured to cause the pump mechanism to aspirate the fluid from the target location into the medicament reservoir when the medicament reservoir does not contain the medicament. The implantable medical pump of claim 15, wherein the processor is configured to provide a generally continuous fluid flow through the at least one catheter by causing the pump mechanism to aspirate the fluid from the target location into the medicament reservoir when the medicament reservoir does not contain the medicament. [Extracted from the article]

Keywords: Amides; Anesthesia; Anilides; Bupivacaine; Health and Medicine; Medical Science; Pain Medicine; Surgery EN Amides Anesthesia Anilides Bupivacaine Health and Medicine Medical Science Pain Medicine Surgery 367 367 1 09/19/23 20230923 NES 230923 2023 SEP 24 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Investigators discuss new findings in medical science. Amides, Anesthesia, Anilides, Bupivacaine, Health and Medicine, Medical Science, Pain Medicine, Surgery. [Extracted from the article]

The news editors obtained a quote from the research from Sungkyunkwan University School of Medicine: "This study aimed to compare the analgesic effects and safety of ITM between laparoscopic and open donor hepatectomy. Keywords: Health and Medicine; Hepatectomy; Surgery EN Health and Medicine Hepatectomy Surgery 909 909 1 09/19/23 20230924 NES 230924 2023 SEP 24 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Researchers detail new data in hepatectomy. [Extracted from the article]

Four time points were established for data collection and, in addition to demographic and anthropometric data, variables related to oncologic pain pathology, initiation of therapy, pain control and complications were collected. Keywords: Pain Medicine EN Pain Medicine 3240 3240 1 09/11/23 20230915 NES 230915 2023 SEP 15 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Researchers detail new data in pain medicine. [Extracted from the article]

Pain and opioid consumption are modifiable factors that may influence the incidence of delirium.1 An intrathecal injection of morphine may lead to a reduction in postoperative pain and reduced systemic opioid consumption." Keywords: Amides; Anesthesia; Anilides; Bupivacaine; Clinical Research; Clinical Trials and Studies; Delirium; Health and Medicine; Hip Fracture; Mental Health; Nervous System Diseases and Conditions; Neurobehavioral Manifestations; Neurologic Manifestations; Opioids; Pain; Pain Medicine EN Amides Anesthesia Anilides Bupivacaine Clinical Research Clinical Trials and Studies Delirium Health and Medicine Hip Fracture Mental Health Nervous System Diseases and Conditions Neurobehavioral Manifestations Neurologic Manifestations Opioids Pain Pain Medicine 1726 1726 1 09/11/23 20230915 NES 230915 2023 SEP 11 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Investigators publish new report on opioids. [Extracted from the article]

According to the news reporters, the research concluded: "Therefore, no superiority of one drug over the other was observed for intrathecal administration with bupivacaine in CS." Keywords: Kermanshah; Iran; Amides; Anesthesia; Anilides; Anxiolytics Sedatives and Hypnotics; Bupivacaine; Bupivacaine Therapy; Central Nervous System Agents; Cesarean Section; Clinical Research; Clinical Trials and Studies; Dexmedetomidine Therapy; Drugs and Therapies; Headache; Health and Medicine; Local Injectable Anesthetics; Narcotic Analgesics; Nervous System Diseases and Conditions; Neurologic Manifestations; Obstetrics; Pain; Pain Medicine; Pharmaceuticals; Pregnancy; Sufentanil Therapy; Surgery; Women's Health EN Kermanshah Iran Amides Anesthesia Anilides Anxiolytics Sedatives and Hypnotics Bupivacaine Bupivacaine Therapy Central Nervous System Agents Cesarean Section Clinical Research Clinical Trials and Studies Dexmedetomidine Therapy Drugs and Therapies Headache Health and Medicine Local Injectable Anesthetics Narcotic Analgesics Nervous System Diseases and Conditions Neurologic Manifestations Obstetrics Pain Pain Medicine Pharmaceuticals Pregnancy Sufentanil Therapy Surgery Women's Health 1028 1028 1 09/11/23 20230912 NES 230912 2023 SEP 11 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Investigators publish new report on Nervous System Diseases and Conditions - Headache. On days 3, 4, and 5, none of the patients in the sufentanil and bupivacaine group had headaches (VAS=0), but patients in the dexmedetomidine and bupivacaine group had some degree of headache (P=0.040). [Extracted from the article]

Keywords: Amides; Anesthesia; Anilides; Bupivacaine; Obstetrics and Gynecology; Pain Medicine EN Amides Anesthesia Anilides Bupivacaine Obstetrics and Gynecology Pain Medicine 1051 1051 1 08/21/23 20230825 NES 230825 2023 AUG 21 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Investigators discuss new findings in obstetrics and gynecology. Amides, Anesthesia, Anilides, Bupivacaine, Obstetrics and Gynecology, Pain Medicine Low dose hyperbaric bupivacaine L-DG group (n=30) received 7.5 mg hyperbaric bupivacaine with 5gm dexmedetomidine and control group S-CG (n=30) received standard dose of hyperbaric bupivacaine of 12.5mg. [Extracted from the article]

Keywords: Spine Pain EN Spine Pain 260 260 1 08/21/23 20230825 NES 230825 2023 AUG 21 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- A new study on spine pain is now available. Keywords for this news article include: Brown University Warren Alpert Medical School, Providence, Rhode Island, United States, North and Central America, Spine Pain. [Extracted from the article]

Keywords: Cancer; Health and Medicine; Oncology; Pain Management; Therapy EN Cancer Health and Medicine Oncology Pain Management Therapy 204 204 1 08/21/23 20230825 NES 230825 2023 AUG 22 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Current study results on cancer have been published. For more information on this research see: Cancer-Related Pain Management in Suitable Intrathecal Therapy Candidates: A Spanish Multidisciplinary Expert Consensus. [Extracted from the article]

The fluid transport system according to claim 14, wherein the pump includes a pressure measuring portion measuring a pressure of the monitoring chamber. Field of the Invention "The present invention relates to a pump for measuring a pressure of fluid to be transferred, a fluid transport system using the same, and a method for operating the system. [Extracted from the article]

Keywords: Surgery EN Surgery 914 914 1 08/14/23 20230818 NES 230818 2023 AUG 20 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Research findings on surgery are discussed in a new report. For more information on this research see: An E-survey study protocol for the perception of African healthcare professionals on the intrathecal injection of antitetanic serum for the treatment of tetanus. For the past two decades, intrathecal injection of antitetanic serum has been described by several meta-analyses as the therapy for the treatment of tetanus with the best outcome.". [Extracted from the article]

Hangzhou, People's Republic of China, Asia, Bone Diseases and Conditions, Health and Medicine, Muscular Atrophy, Musculoskeletal Diseases and Conditions, Neurologic Manifestations, Neuromuscular Diseases and Conditions, Neuromuscular Manifestations, Orthopedics, Pediatrics, Scoliosis, Spinal Curvatures, Spinal Diseases and Conditions, Spinal Muscular Atrophy Keywords: Hangzhou; People's Republic of China; Asia; Bone Diseases and Conditions; Health and Medicine; Muscular Atrophy; Musculoskeletal Diseases and Conditions; Neurologic Manifestations; Neuromuscular Diseases and Conditions; Neuromuscular Manifestations; Orthopedics; Pediatrics; Scoliosis; Spinal Curvatures; Spinal Diseases and Conditions; Spinal Muscular Atrophy EN Hangzhou People's Republic of China Asia Bone Diseases and Conditions Health and Medicine Muscular Atrophy Musculoskeletal Diseases and Conditions Neurologic Manifestations Neuromuscular Diseases and Conditions Neuromuscular Manifestations Orthopedics Pediatrics Scoliosis Spinal Curvatures Spinal Diseases and Conditions Spinal Muscular Atrophy 566 566 1 07/31/23 20230804 NES 230804 2023 AUG 5 (NewsRx) -- By a News Reporter-Staff News Editor at Pediatrics Week -- New research on Neuromuscular Diseases and Conditions - Spinal Muscular Atrophy is the subject of a report. [Extracted from the article]

Keywords: Anesthesia; Health and Medicine; Medical Science; Pain Medicine EN Anesthesia Health and Medicine Medical Science Pain Medicine 1034 1034 1 07/17/23 20230721 NES 230721 2023 JUL 17 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Current study results on medical science have been published. Anesthesia, Health and Medicine, Medical Science, Pain Medicine. [Extracted from the article]

According to news reporting originating from Ningxia, People's Republic of China, by NewsRx correspondents, research stated, "Objective:To investigate the risk factor associated with central nervous system infection, a rare and dire complication after spinal surgery. Keywords: Ningxia; People's Republic of China; Asia; Cell Research; Central Nervous System Diseases and Conditions; Health and Medicine; Leukocytes; Risk and Prevention; Surgery EN Ningxia People's Republic of China Asia Cell Research Central Nervous System Diseases and Conditions Health and Medicine Leukocytes Risk and Prevention Surgery 222 222 1 07/03/23 20230703 NES 230703 2023 JUL 3 (NewsRx) -- By a News Reporter-Staff News Editor at Hematology Week -- Research findings on Central Nervous System Diseases and Conditions are discussed in a new report. [Extracted from the article]

Amides, Analgesic Therapy, Analgesics, Anilides, Bupivacaine, Bupivacaine Therapy, Central Nervous System Agents, Drugs and Therapies, Fentanyl Therapy, Health and Medicine, Local Injectable Anesthetics, Narcotic Analgesics, Orthopedics, Pain Medicine, Pharmaceuticals Keywords: Amides; Analgesic Therapy; Analgesics; Anilides; Bupivacaine; Bupivacaine Therapy; Central Nervous System Agents; Drugs and Therapies; Fentanyl Therapy; Health and Medicine; Local Injectable Anesthetics; Narcotic Analgesics; Orthopedics; Pain Medicine; Pharmaceuticals EN Amides Analgesic Therapy Analgesics Anilides Bupivacaine Bupivacaine Therapy Central Nervous System Agents Drugs and Therapies Fentanyl Therapy Health and Medicine Local Injectable Anesthetics Narcotic Analgesics Orthopedics Pain Medicine Pharmaceuticals 1952 1952 1 07/03/23 20230703 NES 230703 2023 JUL 7 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Investigators publish new report on central nervous system agents. For more information on this research see: Post Operative Analgesic Effect of Intrathecal Fentanyl As An Adjuvant To 0.5% Hyperbaric Bupivacaine Compared To 0.5% Hyperbaric Bupivacaine in Subarachnoid Block in Lower Limb Orthopaedic Surgeries: An Observational Study. [Extracted from the article]

The medical device of claim 10, wherein the at least one temperature sensor comprises a first temperature sensor and a second temperature sensor positioned on opposite sides of the infusion port, and wherein the processor is further configured to determine a flow direction of the cerebrospinal fluid based on the temperature data. Keywords: Business; Drugs and Therapies; Health and Medicine; Healthcare Technology Companies; Medical Device Companies; Medtronic Inc EN Business Drugs and Therapies Health and Medicine Healthcare Technology Companies Medical Device Companies Medtronic Inc 3766 3766 1 07/03/23 20230703 NES 230703 2023 JUL 7 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- A patent by the inventors Bodner, Jeffrey (Plymouth, MN, US), filed on September 17, 2019, was published online on June 13, 2023, according to news reporting originating from Alexandria, Virginia, by NewsRx correspondents. [Extracted from the article]

Mortality at follow-up was significantly lower among patients receiving additional IT therapy (4/30, 13.3%) compared with matched patients receiving systemic anti-TB therapy alone (11/30, 36.7%, P value =0.037). In this retrospective study, patients were categorized into two groups: Group A patients received systematic anti-TB therapy alone, Group B patients received IT INH (50 mg) and prednisolone (25 mg) twice a week together with the same standard systemic anti-TB therapy as Group A, in addition to the standard systemic anti-TB therapy." Keywords: Sichuan; People's Republic of China; Asia; Adrenal Cortical Steroids; Central Nervous System Diseases and Conditions; Central Nervous System Infections; Clinical Research; Clinical Trials and Studies; Drugs and Therapies; Glucocorticoids; Health and Medicine; Hormones; Meningitis; Ophthalmic Preparations; Ophthalmic Steroids; Pharmaceuticals; Prednisolone Therapy EN Sichuan People's Republic of China Asia Adrenal Cortical Steroids Central Nervous System Diseases and Conditions Central Nervous System Infections Clinical Research Clinical Trials and Studies Drugs and Therapies Glucocorticoids Health and Medicine Hormones Meningitis Ophthalmic Preparations Ophthalmic Steroids Pharmaceuticals Prednisolone Therapy 517 517 1 06/26/23 20230626 NES 230626 2023 JUN 26 (NewsRx) -- By a News Reporter-Staff News Editor at TB & Outbreaks Week -- Investigators publish new report on Central Nervous System Diseases and Conditions - Meningitis. [Extracted from the article]