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A study published in The Lancet Gastroenterology & Hepatology found that linaclotide, a medication approved for adults with chronic constipation, was effective in treating functional constipation in children and adolescents. The study involved 330 individuals and showed that those who took linaclotide had significantly more spontaneous bowel movements compared to those who took a placebo. The medication was well-tolerated overall, with diarrhea being the most frequently reported side effect. However, further research is needed to address limitations in the study and determine the long-term safety and efficacy of linaclotide in pediatric patients. [Extracted from the article]

Dr. Sarah Cigna, an ob.gyn. specializing in sexual health, emphasizes the importance of collaboration between ob.gyns and dermatologists in managing vulvar pain and dermatoses. She highlights the need for increased training in vulvar dermatology for both specialties and announces the launch of a joint Vulvar Dermatology Clinic at The George Washington University in 2025. Dr. Cigna provides insights on approaching patient history and exams, diagnosing and treating various vulvar issues, and the significance of considering autoimmune, infectious, and noninfectious causes of vulvar itch. She also discusses the role of mast cell proliferation in vulvar and vestibular pain and itching. [Extracted from the article]

The article discusses the importance of collaboration between obstetricians/gynecologists and dermatologists in managing vulvar dermatoses, highlighting the need for specialized care in this often overlooked area of medicine. The joint Vulvar Dermatology Clinic at The George Washington University will provide monthly clinics for complex cases. The article also covers various causes of vulvar pain and itch, emphasizing the significance of a comprehensive history and examination to determine appropriate treatment. [Extracted from the article]

A randomized clinical trial conducted in the United States found that various surgical approaches to treat vaginal vault prolapse are similarly safe and effective, with high rates of patient satisfaction. The trial included 360 women with vaginal vault prolapse after hysterectomy, who were randomly assigned to undergo different surgical procedures. At 36 months, sacrocolpopexy was found to be superior to native tissue repair for treatment success, while transvaginal mesh repair was noninferior to sacrocolpopexy. All surgical approaches were associated with high treatment satisfaction, improved quality of life, and sexual function. The study suggests that clinicians can discuss the different surgical options with patients and engage in shared decision-making. [Extracted from the article]

Accurately diagnosing recurrent urinary tract infections (rUTIs) in older women is challenging due to age-related conditions and the potential risks of overusing antibiotics. Women aged over 65 have double the rUTI rates compared to younger women, but up to 20% of older women may have bacteria in their urine without it necessarily indicating a rUTI. Clinicians should only test older female patients for rUTIs when symptoms are present and consider alternative treatments such as vaginal estrogen or the drug methenamine. Cranberry supplements and behavioral changes may also be helpful, although evidence is limited. Shared decision-making between clinicians and patients is crucial in cases where the diagnosis is unclear. [Extracted from the article]

The article focuses on vulvodynia, a little-known condition that causes chronic pain in the vulva. The condition is treatable through a personalized therapeutic approach, including accurate diagnosis, CNS dysfunction management, low-dose medication, pelvic floor rehabilitation, psychotherapy, and hygienic measures. Proper understanding and empathy are essential in addressing this condition and improving patients' quality of life.

Latest News FROM JAMA For patients with uterine prolapse, a traditionaltechnique showed superiority, while vaginal estrogencream failed to improve outcomes for vaginal apicalprolapse repair in two new studies published in JAMA. The study findings were limited by several factorsincluding the lack of blinding and the applicability ofthe results only to women without uterine prolapse pastthe hymen, as well as the exclusion of patients withhigher-stage prolapse, the researchers said. [Extracted from the article]

The article reports that City of Hope Orange County is offering new hope for women with cervical, ovarian, uterine, vaginal and vulvar cancer along with world-renowned expertise in gynecologic cancer prevent urogynecology and gynecologic specialty services. It mentions about prevalence of gynecologic cancer is a remainder for women to make their health a priority and consider gynecologic cancer prevention and early detection as important as hear health and bone health.