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Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To investigate the effect of betaine ( TCJ ) on bone loss in type 2 diabetic rats and explore the possible mechanisms. Methods Thirty rats were randomly divided into a control group (CON), a model group (MOD), and a betaine group ( TCJ ), 10 in each group. Among them, type 2 diabetes models were established for MOD and TCJ group. Then TCJ group rats received 50 mg per day I kg betaine treatment for 12 weeks; after the treatment, they were detected by Micro-CT, HE stained sections and Western blot. Results After 12 weeks of treatment, compared with the MOD group, the result of the three-point bending test, Micro-CT and HE staining showed that the number of trabeculae, bone strength and bone density of the TCJ group were significantly improved(P<0.05).The maximum load and elastic modulus, BMD, TV/BV, Th.N, Tb.Th and Tb.Sp of the TCJ group were significantly improved compared with the MOD group ( P-catenin in the TCJ group was significantly increased, while the expression levels ofp-IGF-lR, p-GSK-3r1>, p-r1>-catenin, IGF-lR and GSK-3~ were significantly reduced ( P

Osteoporotic fracture is one of the most common skeletal system diseases in the elderly, which has the characteristics of high incidence, high disability rate, high mortality, and high medical cost. Because of the poor bone quality, comminuted fractures occur frequently, the stability of internal fixation is poor, bed stay time is long, and incidence of refracture is high. Therefore, the surgical treatment of osteoporotic fractures continues to challenge orthopedic surgeon. This paper reviews and summarizes the principles and techniques of surgical treatment for osteoporotic fractures in recent years. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)