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Background: Little is known about patients' or carers' reported experiences of dental care provided using dental behaviour support (DBS) techniques. Qualitative literature can provide unique insight into these experiences. Aim: To explore and synthesize qualitative literature related to patient experience of dental behaviour support. Methods: A PROSPERO‐registered systematic review of qualitative articles was undertaken. Studies were identified through MEDLINE, Embase and PsycINFO. Abstracts were screened by two reviewers and data were extracted to summarize the qualitative findings included within them. A thematic summary approach was used to synthesize the qualitative data identified. Results: Twenty‐three studies were included. Studies primarily explored experiences of dental care of children by speaking to their parents (n = 16), particularly regarding paediatric dental general anaesthesia (DGA) (n = 8). Studies of adults' experiences of DBS (n = 7) covered a range of techniques. Nine studies explored broader dental care experiences and did not study specific DBS approaches. A thematic synthesis identified five themes applicable across the studies identified: Trust and the therapeutic alliance supporting effective care delivery; considered information sharing often alleviated anticipatory anxiety; control and autonomy‐reduced anxieties; variations in the perceived treatment successes and failures of DBS techniques; and DBS techniques produced longer positive and negative impacts on patients beyond direct care provision. Conclusion: Qualitative research has been under‐utilized in research on DBS techniques. Care experiences of most DBS techniques outside of paediatric DGA are poorly understood. Building trust with patients and enabling autonomy appear to support positive patient‐reported experiences of care. [ABSTRACT FROM AUTHOR]

Bursting bubbles transport bacteria, viruses, and other marine particles across the air‐sea interface. This effect is enhanced when particles are hydrophobic and cling to the bubbles as they rise. Recent studies suggest that plastic particles, a major ocean pollutant, can also be transported by sea spray. However, estimates of plastic transport via this pathway have large uncertainties due to limited size detection techniques in field studies and few lab studies. An understanding of the number and size of particles carried in the smallest drops, which have the longest residence time in the atmosphere, is missing from current literature. Here, we develop a modeling framework to provide bounds on the number, area, and volume transport of non‐scavenged hydrophilic and fully‐scavenged hydrophobic particles of radii between 0.1 and 100 μm for a range of jet and film drops. For droplets containing plastic particulates, we predict particle enrichment is significantly higher in jet drops than film drops. For particles in these jet drops, our results suggest that in the absence of bubble scavenging, the number distribution is dominated by smaller plastics, the mass/volume distribution by larger plastics, and surface area distribution is balanced across plastic size. Whereas for hydrophobic particles, scavenging dramatically modifies these distributions, enhancing certain particle–droplet size combinations by over four orders of magnitude. Our predictions suggest critical effects of enrichment in air‐sea particle transport and highlight the variable dependencies on bubble and particle size, improving our theoretical understanding of plastic and marine particle transport and identifying modeling assumptions to refine with experimental measurements. Plain Language Summary: Plastic particles in the oceans are a topic of growing concern due to their spread throughout the environment. The oceans are a reservoir of plastics, however recent studies have found that bursting bubbles can eject the plastic into the atmosphere, where it has the potential to be transported much further. We create a first‐principles modeling framework to estimate the expected effects of particle and bubble size on the transport of hydrophobic and hydrophilic particles. We predict bounds on the extent that hydrophobic particles, like some plastics, may be highly selected to become airborne compared to hydrophilic particles. Selectivity effects are especially significant for the small airborne drops, which is important if it is the size of the drops rather than the size of the particle that influences the time they remain suspended in the atmosphere. This model provides a means to untangle the effects of bubble and particle size, as well as provide theoretical predictions to test against experimental data. This generic framework can be applied to the air‐sea transport of particles beyond plastics, with important implications to the selective aerosolization of other particles such as viruses or bacteria. Key Points: Modeling reveals how the air‐sea transfer of hydrophilic/phobic particles between 0.1 and 100 μm in radius varies with particle and bubble sizeParticle hydrophobicity may be key to air‐sea transport as particles are selectively aerosolized up to 300,000x under the conditions modeledFor drops containing plastic particulates, model predicts particle enrichment is significantly higher in jet drops than film drops [ABSTRACT FROM AUTHOR]

Background: Dental behavior support (DBS) describes all techniques used by dental professionals to ensure that dental care is safe, effective, and acceptable. There is a need to standardize outcome measures across DBS techniques to reduce heterogeneity, limit selective reporting, promote consistency, and optimize outcomes across DBS research. A comprehensive review of existing measures is a prerequisite to understanding potential outcomes related to the area of interest. Aim: This review had three aims: first, to identify the outcome measures (OMs) reported in trials of dental behavior support; second, to categorize the component DBS techniques reported within interventions according to emerging agreed terminology; and, third, to map outcome measures to intervention type. Methods: A scoping review of trials evaluating DBS techniques was undertaken from 2012 to 2022. The review was prospectively registered. Studies were identified through Medline, Embase, and PsycINFO. Study abstracts were screened by two reviewers. Data were extracted by single selector. Outcome measures were sorted according to measurement domains (physiological, behavioral, psychological, and treatment). Responses were assimilated and summed to produce a refined list of distinguishable outcome measures. Intervention types were categorized according to accepted descriptors. Frequencies were presented; associations between outcome domain and DBS type were also reported (Chi‐square test of independence). Results: A total of 344 trials were included in the review from an initial 14,793 titles / title and abstracts screened. Most involved children (n = 215), most were from India (n = 104), involving basic dental care (n = 117). The median number of outcome measures per trial was four (range = 1–12); 1,317 individual outcomes were reported, categorized as: psychological (n = 501, 38.0%); physiological (n = 491, 37.3%), behavioral (n = 123, 9.3%) or, treatment‐related (n = 202, 15.3%). DBS interventions were split between 239 (45.7%) pharmacological and 283 (54.1%) non‐pharmacological; 96.6% of interventions mapped to accepted descriptors. A significant relationship was noted between the type of intervention and the outcome domain reported. Conclusion: The findings demonstrate massive variation in outcome measures of DBS interventions that likely lead to unnecessary heterogeneity, selective reporting, and questionable relevance in the literature. A large range of DBS interventions were mapped according to BeSiDe list. There is a need for consensus on a core outcome set across the spectrum of DBS techniques. [ABSTRACT FROM AUTHOR]

In the biotechnology industry, ensuring the health and viability of mammalian cells, especially Chinese Hamster Ovary (CHO) cells, plays a significant role in the successful production of therapeutic agents. These cells are typically cultivated in aerated bioreactors, where they encounter fluid stressors from rapidly deforming bubbles. These stressors can disrupt essential biological processes and potentially lead to cell death. However, the impact of these transient, elevated stressors on cell viability remains elusive. In this study, we first employ /cgqamicrofluidics to expose CHO cells near to bubbles undergoing pinch‐off, subsequently collecting and assaying the cells to quantify the reduction in viability. Observing a significant impact, we set out to understand this phenomenon. We leverage computational fluid dynamics and numerical particle tracking to map the stressor field history surrounding a rapidly deforming bubble. Separately, we expose CHO cells to a known stressor level in a flow constriction device, collecting and assaying the cells to quantify the reduction in viability. By integrating the numerical data and results from the flow constriction device experiments, we develop a predictive model for cell viability reduction. We validate this model by comparing its predictions to the earlier microfluidic results, observing good agreement. Our findings provide critical insights into the relationship between bubble‐induced fluid stressors and mammalian cell viability, with implications for bioreactor design and cell culture protocol optimization in the biotechnology sector. [ABSTRACT FROM AUTHOR]

Objective To examine the impact of nursing team size and composition on inpatient hospital mortality. Design A retrospective longitudinal study using linked nursing staff rostering and patient data. Multilevel conditional logistic regression models with adjustment for patient characteristics, day and time-invariant ward differences estimated the association between inpatient mortality and staffing at the ward-day level. Two staffing measures were constructed: the fraction of target hours worked (fill-rate) and the absolute difference from target hours. Setting Three hospitals within a single National Health Service Trust in England. Participants 19 287 ward-day observations with information on 4498 nurses and 66 923 hospital admissions in 53 inpatient hospital wards for acutely ill adult patients for calendar year 2017. Main outcome measure In-hospital deaths. Results A statistically significant association between the fill-rate for registered nurses (RNs) and inpatient mortality (OR 0.9883, 95% CI 0.9773 to 0.9996, p=0.0416) was found only for RNs hospital employees. There was no association for healthcare support workers (HCSWs) or agency workers. On average, an extra 12- hour shift by an RN was associated with a reduction in the odds of a patient death of 9.6% (OR 0.9044, 95% CI 0.8219 to 0.9966, p=0.0416). An additional senior RN (in NHS pay band 7 or 8) had 2.2 times the impact of an additional band 5 RN (fill-rate for bands 7 and 8: OR 0.9760, 95% CI 0.9551 to 0.9973, p=0.0275; band 5: OR 0.9893, 95% CI 0.9771 to 1.0017, p=0.0907). Conclusions RN staffing and seniority levels were associated with patient mortality. The lack of association for HCSWs and agency nurses indicates they are not effective substitutes for RNs who regularly work on the ward. [ABSTRACT FROM AUTHOR]

This article describes a recent Oxfordshire Big Science Event (BSE), which was combined with Science Week in Bure Park Primary School and involved a competition in which primary school children throughout Oxfordshire devised, carried out, and recorded data from science investigations to answer questions that interested them. Teams of children needed to come up with their own open-ended science investigation (whether a fair test, survey, observation over time, or secondary research approach). They then had to present their work on a large poster for other children and teachers to judge. To enable the children to generate their own investigations, they were presented with an open question: "Does the same thing happen each time a solid is mixed with a liquid?" The children were invited to move around a carousel of various materials placed at stations around the room and to use iPads to aid their recording. The authors report that using the iPads to video and review events more closely helped to develop observational skills and discussion as well as stimulate curiosity. They also observed that using the multimodality of the iPad to record worked particularly well for very rapid or very slow reactions. They found that the process of capturing experimental reactions with iPads and reviewing recordings allowed students to become more reflective and constructively self-critical in science investigations.