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Your search keyword '"Sota, Masahiro"' showing total 21 results
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21 results on '"Sota, Masahiro"'

15. MOESM3 of Development of a strictly regulated xylose-induced expression system in Streptomyces

Author

Noguchi, Yuji, Kashiwagi, Norimasa, Uzura, Atsuko, Ogino, Chiaki, Kondo, Akihiko, Ikeda, Haruo, and Sota, Masahiro

Abstract

Additional file 3: Figure S3. (A) Chitobiase activity and (B) optical density (600 nm) of S. lividans XCPR after 48, 72, and 96 h cultivation. After 48 h, D-xylose was added to a final concentration of 0.0, 0.5, 1.0, and 2.0%. Cultivation was continued for 24 and 48 h (72 and 96 h total).

Published
2018
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20. Metabolic engineering of Corynebacterium glutamicumfor production of sunscreen shinorine

Author

Tsuge, Yota, Kawaguchi, Hideo, Yamamoto, Shogo, Nishigami, Yoshiko, Sota, Masahiro, Ogino, Chiaki, and Kondo, Akihiko

Abstract

AbstractUltraviolet-absorbing chemicals are useful in cosmetics and skin care to prevent UV-induced skin damage. We demonstrate here that heterologous production of shinorine, which shows broad absorption maxima in the UV-A and UV-B region. A shinorine producing Corynebacterium glutamicumstrain was constructed by expressing four genes from Actinosynnema mirumDSM 43827, which are responsible for the biosynthesis of shinorine from sedoheptulose-7-phosphate in the pentose phosphate pathway. Deletion of transaldolase encoding gene improved shinorine production by 5.2-fold. Among the other genes in pentose phosphate pathway, overexpression of 6-phosphogluconate dehydrogenase encoding gene further increased shinorine production by 60% (19.1 mg/L). The genetic engineering of the pentose phosphate pathway in C. glutamicumimproved shinorine production by 8.3-fold in total, and could be applied to produce the other chemicals derived from sedoheptulose-7-phosphate.

Published
2018
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21. Evaluation of radiation dose to the lens in interventional cardiology physicians before and after dose limit regulation changes.

Author

Sagehashi K, Haga Y, Takahira S, Tanabe M, Nakamura M, Sota M, Kaga Y, Abe M, Tada N, and Chida K

Abstract

In response to the International Commission on Radiological Protection (ICRP), which lowered the lens equivalent dose limit, Japan lowered the lens dose limit from 150 mSv/year to 100 mSv/5 years and 50 mSv/year, with this new rule taking effect on April 1, 2021. DOSIRIS® is a dosimeter that can accurately measure lens dose. Herein, we investigated lens dose in interventional cardiology physicians one year before and after the reduction of the lens dose limit using a neck dosimeter and lens dosimeter measurements. With an increase in the number of cases, both personal dose equivalent at 0.07 mm [Hp(0.07), neck dosimeter] and personal dose equivalent at 3 mm depth [Hp(3), lens dosimeter] increased for most of the physicians. The Hp(3) of the lens considering the shielding effect of the Pb glasses using lens dosimeter exceeded 20 mSv/year for two of the 14 physicians. Protection from radiation dose will become even more important in the future, as these two physicians may experience radiation dose exceeding 100 mSv/5 years. The average dose per procedure increased, but not significantly. There was a strong correlation between the neck dosimeter and lens dosimeter scores, although there was no significant change before and after the lens dose limit was lowered. This correlation was particularly strong for physicians who primarily treated patients. As such, it is possible to infer accurate lens doses from neck doses in physicians who primarily perform diagnostics. However, it is desirable to use a dosimeter that can directly measure Hp(3) because of the high lens dose., (© 2024 Society for Radiological Protection. Published on behalf of SRP by IOP Publishing Limited. All rights, including for text and data mining, AI training, and similar technologies, are reserved.)

Published
2024
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